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Items: 1 to 20 of 72

1.
Seipin overexpression attenuates cerebral ischemia‐reperfusion injury via preventing apoptosis and autophagy
Xiaoxi Zhu, Xiaoqiong An, Ming Chen, Dongfen Guo, Peng Xie, Bi Wang, Zhi Huang, Wenfeng Yu
Brain Behav. 2023 Dec; 13(12): e3195. Published online 2023 Oct 27. doi: 10.1002/brb3.3195
PMCID:
PMC10726895
AbstractArticlePDF–1.8M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b
Shunsuke Saito, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Kazutoshi Mori
eLife. 2022; 11: e74805. Published online 2022 Nov 29. doi: 10.7554/eLife.74805
PMCID:
PMC9708084
AbstractArticlePDF–12M
4.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
5.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
6.
Retinyl esters form lipid droplets independently of triacylglycerol and seipin
Martijn R. Molenaar, Kamlesh K. Yadav, Alexandre Toulmay, Tsjerk A. Wassenaar, Muriel C. Mari, Lucie Caillon, Aymeric Chorlay, Ivan E. Lukmantara, Maya W. Haaker, Richard W. Wubbolts, Martin Houweling, Arie Bas Vaandrager, Xavier Prieur, Fulvio Reggiori, Vineet Choudhary, Hongyuan Yang, Roger Schneiter, Abdou Rachid Thiam, William A. Prinz, J. Bernd Helms
J Cell Biol. 2021 Oct 4; 220(10): e202011071. Published online 2021 Jul 29. doi: 10.1083/jcb.202011071
PMCID:
PMC8327380
AbstractArticlePDF–5.3M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
Seipin accumulates and traps diacylglycerols and triglycerides in its ring-like structure
Valeria Zoni, Rasha Khaddaj, Ivan Lukmantara, Wataru Shinoda, Hongyuan Yang, Roger Schneiter, Stefano Vanni
Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2017205118. Published online 2021 Mar 5. doi: 10.1073/pnas.2017205118
PMCID:
PMC7958289
AbstractArticlePDF–2.4M
9.
Seipin traps triacylglycerols to facilitate their nanoscale clustering in the endoplasmic reticulum membrane
Xavier Prasanna, Veijo T. Salo, Shiqian Li, Katharina Ven, Helena Vihinen, Eija Jokitalo, Ilpo Vattulainen, Elina Ikonen
PLoS Biol. 2021 Jan; 19(1): e3000998. Published online 2021 Jan 22. doi: 10.1371/journal.pbio.3000998
PMCID:
PMC7857593
AbstractArticlePDF–4.6M
10.
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner
Kamil Sołtysik, Yuki Ohsaki, Tsuyako Tatematsu, Jinglei Cheng, Asami Maeda, Shin-ya Morita, Toyoshi Fujimoto
J Cell Biol. 2021 Jan 4; 220(1): e202005026. Published online 2020 Dec 14. doi: 10.1083/jcb.202005026
PMCID:
PMC7737703
AbstractArticlePDF–4.4M
11.
The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
Kaushik Bhattacharya, Lorenz Weidenauer, Tania Morán Luengo, Ellis C. Pieters, Pablo C. Echeverría, Lilia Bernasconi, Diana Wider, Yashar Sadian, Margreet B. Koopman, Matthieu Villemin, Christoph Bauer, Stefan G. D. Rüdiger, Manfredo Quadroni, Didier Picard
Nat Commun. 2020; 11: 5975. Published online 2020 Nov 25. doi: 10.1038/s41467-020-19783-w
PMCID:
PMC7688965
AbstractArticlePDF–13M
12.
SEIPIN: A Key Factor for Nuclear Lipid Droplet Generation and Lipid Homeostasis
Yi Jin, Yanjie Tan, Pengxiang Zhao, Zhuqing Ren
Int J Mol Sci. 2020 Nov; 21(21): 8208. Published online 2020 Nov 2. doi: 10.3390/ijms21218208
PMCID:
PMC7663086
AbstractArticlePDF–1.9M
13.
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani
Oncogene. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9
PMCID:
PMC7523706
AbstractArticlePDF–2.3M
14.
Celia’s encephalopathy and c.974dupG in BSCL2 gene: a hidden change in a known variant
Sofía Sánchez-Iglesias, Melissa Crocker, Mar O’Callaghan, Alejandra Darling, Angels García-Cazorla, Rosario Domingo-Jiménez, Ana Castro, Antía Fernández-Pombo, Álvaro Ruibal, Pablo Aguiar, Miguel Garrido-Pumar, Antonio Rodríguez-Núñez, Julián Álvarez-Escudero, Rebecca J. Brown, David Araújo-Vilar
Neurogenetics. Author manuscript; available in PMC 2020 Jun 11.
Published in final edited form as: Neurogenetics. 2019 May; 20(2): 73–82. Published online 2019 Mar 23. doi: 10.1007/s10048-019-00574-5
PMCID:
PMC7288395
AbstractArticlePDF–492K
15.
Lipid droplet assembly factor-1 and seipin form a lipid droplet assembly complex
Jeeyun Chung, Xudong Wu, Talley J. Lambert, Zon Weng Lai, Tobias C. Walther, Robert V. Farese, Jr.
Dev Cell. Author manuscript; available in PMC 2020 Dec 2.
Published in final edited form as: Dev Cell. 2019 Dec 2; 51(5): 551–563.e7. Published online 2019 Nov 7. doi: 10.1016/j.devcel.2019.10.006
PMCID:
PMC7235935
AbstractArticlePDF–1.7M
16.
Novel compound heterozygous variant of BSCL2 identified by whole exome sequencing and multiplex ligation-dependent probe amplification in an infant with congenital generalized lipodystrophy
Bobo Xie, Xin Fan, Yaqin Lei, Shang Yi, Qi Yang, Jin Wang, Zailong Qin, Fei Shen, Jingsi Luo, Yiping Shen
Mol Med Rep. 2020 Jun; 21(6): 2296–2302. Published online 2020 Mar 23. doi: 10.3892/mmr.2020.11036
PMCID:
PMC7185175
AbstractArticlePDF–709K
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation
M. F. Michelle Sim, Elisa Persiani, Md. Mesbah Uddin Talukder, George D. Mcilroy, Ahlima Roumane, J. Michael Edwardson, Justin J. Rochford
Sci Rep. 2020; 10: 3259. Published online 2020 Feb 24. doi: 10.1038/s41598-020-59982-5
PMCID:
PMC7039881
AbstractArticlePDF–1.9M
19.
Discovering metabolic disease gene interactions by correlated effects on cellular morphology
Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia
Mol Metab. 2019 Jun; 24: 108–119. Published online 2019 Mar 13. doi: 10.1016/j.molmet.2019.03.001
PMCID:
PMC6531784
AbstractArticlePDF–2.4M
20.
Promethin Is a Conserved Seipin Partner Protein
Inês G. Castro, Michal Eisenberg-Bord, Elisa Persiani, Justin J. Rochford, Maya Schuldiner, Maria Bohnert
Cells. 2019 Mar; 8(3): 268. Published online 2019 Mar 21. doi: 10.3390/cells8030268
PMCID:
PMC6468817
AbstractArticlePDF–3.7M

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