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Select item 110752181.

UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells

Bo Yang, Weihua Chen, Tianyi Tao, Jun Zhang, Dehui Kong, Jidong Hao, Chao Yu, Guoqiang Liao, Hua Gong

Biol Direct. 2024; 19: 35. Published online 2024 May 7. doi: 10.1186/s13062-024-00469-y

PMCID:: PMC11075218

Abstract Article PDF–7.5M

Select item 107682842.

R-spondin-1 induces Axin degradation via the LRP6-CK1ε axis

Lifeng Tan, Mengfang Yan, Zijie Su, Hanbin Wang, Huan Li, Xibao Zhao, Shanshan Liu, Long Zhang, Qi Sun, Desheng Lu

Cell Commun Signal. 2024; 22: 14. Published online 2024 Jan 5. doi: 10.1186/s12964-023-01456-y

PMCID:: PMC10768284

Abstract Article PDF–5.7M

Select item 105027353.

AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia

Paulien Terhal, Anton J. Venhuizen, Davor Lessel, Wen-Hann Tan, Abdulrahman Alswaid, Regina Grün, Hamad I. Alzaidan, Simon von Kroge, Nada Ragab, Maja Hempel, Christian Kubisch, Eduardo Novais, Alba Cristobal, Kornelia Tripolszki, Peter Bauer, Björn Fischer-Zirnsak, Rutger A.J. Nievelstein, Atty van Dijk, Peter Nikkels, Ralf Oheim, Heidi Hahn, Aida Bertoli-Avella, Madelon M. Maurice, Uwe Kornak

Am J Hum Genet. 2023 Sep 7; 110(9): 1470–1481. Published online 2023 Aug 14. doi: 10.1016/j.ajhg.2023.07.011

PMCID:: PMC10502735

Abstract Article PDF–2.9M

Select item 104998214.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 104457385.

An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity

Stephanie M. Almeida, Sofiia Ivantsiv, Rieko Niibori, Wade H. Dunham, Brooke A. Green, Liang Zhao, Anne-Claude Gingras, Sabine P. Cordes

Dis Model Mech. 2023 Aug 1; 16(8): dmm049762. Published online 2023 Aug 17. doi: 10.1242/dmm.049762

PMCID:: PMC10445738

Abstract Article

Select item 104420756.

The Axin scaffold protects the kinase GSK3β from cross-pathway inhibition

Maire Gavagan, Noel Jameson, Jesse G Zalatan

eLife. 2023; 12: e85444. Published online 2023 Aug 7. doi: 10.7554/eLife.85444

PMCID:: PMC10442075

Abstract Article PDF–1.9M

Select item 103038657.

Association between AXIN1 gene polymorphism (rs9921222) of WNT signaling pathway and susceptibility to osteoporosis in Egyptian patients: a case-control study

Eman Saad Nassar, Rehab Elnemr, Ahmed Shaaban, Asmaa Abd Elhameed, Raghda Saad Zaghloul Taleb

BMC Musculoskelet Disord. 2023; 24: 527. Published online 2023 Jun 28. doi: 10.1186/s12891-023-06644-y

PMCID:: PMC10303865

Abstract Article PDF–1.1M

Select item 101516158.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100729069.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 999012010.

Interactomes of Glycogen Synthase Kinase-3 Isoforms

Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett

J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825

PMCID:: PMC9990120

Abstract Article PDF–3.7M

Select item 983398511.

Association of AXIN1 rs12921862 C/A and rs1805105 G/A and CTSB rs12898 G/A polymorphisms with papillary thyroid carcinoma: A case–control study

Shaghayegh Saljooghi, Zahra Heidari, Mohsen Saravani, Mahnaz Rezaei, Saeedeh Salimi

J Clin Lab Anal. 2023 Jan; 37(1): e24804. Published online 2022 Dec 12. doi: 10.1002/jcla.24804

PMCID:: PMC9833985

Abstract Article PDF–535K

Select item 978918212.

Axin1: a novel scaffold protein joins the antiviral network of interferon

Yujie Guo, Gayan Bamunuarachchi, Kishore Vaddadi, Zhengyu Zhu, Chaitanya Gandikota, Kainat Ahmed, Samuel Pushparaj, Sunil More, Xiao Xiao, Xiaoyun Yang, Yurong Liang, Sanjay Mukherjee, Pradyumna Baviskar, Chaoqun Huang, Shitao Li, Antonius G. P. Oomens, Jordan Patrick Metcalf, Lin Liu

Mol Microbiol. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Mol Microbiol. 2022 Oct 29 : 10.1111/mmi.14995. Published online 2022 Oct 29. doi: 10.1111/mmi.14995

PMCID:: PMC9789182

Abstract Article PDF–803K

Select item 955841913.

Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery

Menghan Wang, Xing Ma, Guoyu Wang, Yanan Song, Miao Zhang, Zhongchao Mai, Borong Zhou, Ying Ye, Wei Xia

Cell Mol Biol Lett. 2022; 27: 92. Published online 2022 Oct 12. doi: 10.1186/s11658-022-00394-w

PMCID:: PMC9558419

Abstract Article PDF–4.5M

Select item 929844914.

ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation

Dongsheng Bai, Jiaying Du, Xiumin Bu, Wangjia Cao, Tifan Sun, Jiawei Zhao, Yue Zhao, Na Lu

Autophagy. 2022; 18(7): 1673–1693. Published online 2021 Nov 25. doi: 10.1080/15548627.2021.1997051

PMCID:: PMC9298449

Abstract Article PDF–7.7M

Select item 911973615.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 907223116.

WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit

Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao

Acta Pharm Sin B. 2022 Mar; 12(3): 1225–1239. Published online 2021 Oct 26. doi: 10.1016/j.apsb.2021.10.021

PMCID:: PMC9072231

Abstract Article PDF–2.9M

Select item 905602617.

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis

Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485

PMCID:: PMC9056026

Abstract Article PDF–1.0M

Select item 890518918.

Metformin Combining PD-1 Inhibitor Enhanced Anti-Tumor Efficacy in STK11 Mutant Lung Cancer Through AXIN-1-Dependent Inhibition of STING Ubiquitination

Zhiguo Wang, Conghua Lu, Kejun Zhang, Caiyu Lin, Fang Wu, Xiaolin Tang, Di Wu, Yuanyao Dou, Rui Han, Yubo Wang, Chao Hou, Qin Ouyang, Mingxia Feng, Yong He, Li Li

Front Mol Biosci. 2022; 9: 780200. Published online 2022 Feb 23. doi: 10.3389/fmolb.2022.780200