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Items: 1 to 20 of 298

1.
The Combined Immunohistochemical Expression of GLI1 and BCOR in Synovial Sarcomas for the Identification of Three Risk Groups and Their Prognostic Outcomes: A Study of 52 Patients
Francisco Giner, Emilio Medina-Ceballos, Raquel López-Reig, Isidro Machado, José Antonio López-Guerrero, Samuel Navarro, Luis Alberto Rubio-Martínez, Mónica Espino, Empar Mayordomo-Aranda, Antonio Llombart-Bosch
Int J Mol Sci. 2024 Jul; 25(14): 7615. Published online 2024 Jul 11. doi: 10.3390/ijms25147615
PMCID:
PMC11276717
AbstractArticlePDF–4.1M
2.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
3.
PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As2O3 by stabilizing oncoprotein PML-RARα
Xinping Huang, Yongfeng Yang, Dan Zhu, Yan Zhao, Min Wei, Ke Li, Hong-hu Zhu, Xiaofeng Zheng
Cell Mol Life Sci. 2022 Jun; 79(6): 319. Published online 2022 May 27. doi: 10.1007/s00018-022-04358-3
PMCID:
PMC11072021
AbstractArticlePDF–9.5M
4.
PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells
Casey D. S. Katerndahl, Olivia R. S. Rogers, Ryan B. Day, Ziheng Xu, Nichole M. Helton, Sai Mukund Ramakrishnan, Christopher A. Miller, Timothy J. Ley
Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2317690121. Published online 2024 Apr 22. doi: 10.1073/pnas.2317690121
PMCID:
PMC11067031
AbstractArticlePDF–7.2M
5.
BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion
Azadeh Ebrahimi, Andreas Waha, Jens Schittenhelm, Georg Gohla, Martin U Schuhmann, Torsten Pietsch
Acta Neuropathol Commun. 2024; 12: 60. Published online 2024 Apr 18. doi: 10.1186/s40478-024-01780-5
PMCID:
PMC11025138
AbstractArticlePDF–6.3M
6.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
7.
Clinical Relevance of Differential RARα and PPARβ/δ Expression in Myelodysplastic Syndromes
NIKOLAY KALITIN, GALINA DUDINA, NATALIA KOSTRITSA, ANASTASIYA SIVIRINOVA, ANDREY VAIMAN, AIDA KARAMYSHEVA
In Vivo. 2024 Mar-Apr; 38(2): 657–664. Published online 2024 Mar 3. doi: 10.21873/invivo.13486
PMCID:
PMC10905464
AbstractArticlePDF–417K
8.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
AbstractArticlePDF–9.3M
9.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
10.
BCOR Expression in Mullerian Adenosarcoma: A Potential Diagnostic Pitfall
Vidarshi Muthukumarana, Daniel J. Fix, Simona Stolnicu, Kay J. Park, Robert A. Soslow, Ryma Benayed, Marc Ladanyi, Cristina R. Antonescu, Sarah Chiang
Am J Surg Pathol. Author manuscript; available in PMC 2023 May 17.
Published in final edited form as: Am J Surg Pathol. 2020 Jun; 44(6): 765–770. doi: 10.1097/PAS.0000000000001445
PMCID:
PMC10189887
AbstractArticlePDF–1.8M
11.
Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα
Qian-qian Wang, Liaqat Hussain, Pei-han Yu, Chang Yang, Chen-ying Zhu, Ya-fang Ma, Si-chun Wang, Tao Yang, Yuan-yuan Kang, Wen-juan Yu, Yasen Maimaitiyiming, Hua Naranmandura
Acta Pharmacol Sin. 2023 Apr; 44(4): 822–831. Published online 2022 Oct 10. doi: 10.1038/s41401-022-01001-6
PMCID:
PMC10042863
AbstractArticlePDF–3.7M
12.
Soft Tissue and Visceral Organ Sarcomas With BCOR Alterations
Sarah B. Whittle, Stephanie Fetzko, Angshumoy Roy, Rajkumar Venkatramani
J Pediatr Hematol Oncol. Author manuscript; available in PMC 2023 Mar 20.
Published in final edited form as: J Pediatr Hematol Oncol. 2022 Jul 1; 44(5): 195–200. Published online 2022 May 4. doi: 10.1097/MPH.0000000000002480
PMCID:
PMC10026688
AbstractArticlePDF–613K
13.
Multi-omics and machine learning reveal context-specific gene regulatory activities of PML::RARA in acute promyelocytic leukemia
William Villiers, Audrey Kelly, Xiaohan He, James Kaufman-Cook, Abdurrahman Elbasir, Halima Bensmail, Paul Lavender, Richard Dillon, Borbála Mifsud, Cameron S. Osborne
Nat Commun. 2023; 14: 724. Published online 2023 Feb 9. doi: 10.1038/s41467-023-36262-0
PMCID:
PMC9911410
AbstractArticlePDF–3.7M
14.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
15.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M
16.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
17.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
AbstractArticlePDF–2.7M
18.
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
Eva J. Schaefer, Helen C. Wang, Hannah Q. Karp, Clifford A. Meyer, Paloma Cejas, Micah D. Gearhart, Emmalee R. Adelman, Iman Fares, Annie Apffel, Klothilda Lim, Yingtian Xie, Christopher J. Gibson, Monica Schenone, H. Moses Murdock, Eunice S. Wang, Lukasz P. Gondek, Martin P. Carroll, Rahul S. Vedula, Eric S. Winer, Jacqueline S. Garcia, Richard M. Stone, Marlise R. Luskin, Steven A. Carr, Henry W. Long, Vivian J. Bardwell, Maria E. Figueroa, R. Coleman Lindsley
Blood Cancer Discov. 2022 Mar 1; 3(2): 116–135. Published online 2022 Mar 4. doi: 10.1158/2643-3230.BCD-21-0115
PMCID:
PMC9414116
AbstractArticlePDF–11M
19.
Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling
Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li
Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z
PMCID:
PMC9392063
AbstractArticlePDF–2.0M
20.
Paediatric BCOR‐associated sarcomas with a novel long spliced internal tandem duplication of BCOR exon 15
Jian Yuan Goh, Chik Hong Kuick, Masahiro Sugiura, Sze Jet Aw, Manli Zhao, Hongfeng Tang, Sandini Gunaratne, Fucun Zhu, Lin Cai, Bin Tean Teh, Paul S Thorner, Kenneth Tou En Chang
J Pathol Clin Res. 2022 Sep; 8(5): 470–480. Published online 2022 Jul 14. doi: 10.1002/cjp2.287
PMCID:
PMC9353662
AbstractArticlePDF–2.3M

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