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Select item 111141141.

USP22 as a key regulator of glycolysis pathway in osteosarcoma: insights from bioinformatics and experimental approaches

Qiao Zhang, Jinwei Zhu, Jian Xie, Yurong Gu, Lu Chen

PeerJ. 2024; 12: e17397. Published online 2024 May 20. doi: 10.7717/peerj.17397

PMCID:: PMC11114114

Abstract Article PDF–23M

Select item 108631692.

USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

Evangelos Prokakis, Husam Bamahmoud, Shaishavi Jansari, Lena Fritsche, Alexander Dietz, Angela Boshnakovska, Peter Rehling, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz

Cell Commun Signal. 2024; 22: 120. Published online 2024 Feb 12. doi: 10.1186/s12964-023-01441-5

PMCID:: PMC10863169

Abstract Article PDF–12M

Select item 105918363.

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113099. Published online 2023 Sep 8. doi: 10.1016/j.celrep.2023.113099

PMCID:: PMC10591836

Abstract Article PDF–2.6M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729065.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100085836.

USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma

Kai Zeng, Weiwen Xie, Chunyu Wang, Shengli Wang, Wei Liu, Yingjie Su, Lin Lin, Renlong Zou, Ge Sun, Baosheng Zhou, Manlin Wang, Ruina Luan, Yu Bai, Yunlong Huo, Shigeaki Kato, Xinping Zhong, Yue Zhao

Cell Death Dis. 2023 Mar; 14(3): 194. Published online 2023 Mar 11. doi: 10.1038/s41419-023-05699-y

PMCID:: PMC10008583

Abstract Article PDF–5.6M

Select item 98270937.

The ubiquitin-specific peptidase 22 is a deubiquitinase of CD73 in breast cancer cells

Shana Gregory, Yanan Xu, Ping Xie, Jie Fan, Beixue Gao, Nikita Mani, Radhika Iyer, Amy Tang, Juncheng Wei, Shuvam Mohan Chaudhuri, Shengnan Wang, Huiping Liu, Bin Zhang, Deyu Fang

Am J Cancer Res. 2022; 12(12): 5564–5575. Published online 2022 Dec 15.

PMCID:: PMC9827093

Abstract Article PDF–1.4M

Select item 97448968.

PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells

Qing Li, Liren Zhang, Wenhua You, Jiali Xu, Jingjing Dai, Dongxu Hua, Ruizhi Zhang, Feifan Yao, Suiqing Zhou, Wei Huang, Yongjiu Dai, Yu Zhang, Tasiken Baheti, Xiaofeng Qian, Liyong Pu, Jing Xu, Yongxiang Xia, Chuanyong Zhang, Jinhai Tang, Xuehao Wang

Nat Commun. 2022; 13: 7677. Published online 2022 Dec 12. doi: 10.1038/s41467-022-35469-x

PMCID:: PMC9744896

Abstract Article PDF–11M

Select item 96361329.

Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis

Zelong Han, Ming Liu, Yuxin Xie, Kunlin Zeng, Ziling Zhan, Yanwen Chen, Li Wang, Xiaoxia Chen, Yaxin Luo, Yu Zeng, Hongchao Zhan, Yingzhuo Lin, Keqin Zhang, Xiaoxia Zhu, Side Liu, Xiaobei Luo, Aidong Zhou

Cell Death Discov. 2022; 8: 445. Published online 2022 Nov 4. doi: 10.1038/s41420-022-01241-9

PMCID:: PMC9636132

Abstract Article PDF–5.6M

Select item 948418610.

Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression

Ting Sun, Keqiang Zhang, Wendong Li, Yunze Liu, Rajendra P. Pangeni, Aimin Li, Leonidas Arvanitis, Dan J. Raz

Cell Commun Signal. 2022; 20: 147. Published online 2022 Sep 19. doi: 10.1186/s12964-022-00946-9

PMCID:: PMC9484186

Abstract Article PDF–2.4M

Select item 937779711.

Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression

Qiangqiang Liu, Qian Luo, Jianyu Feng, Yanping Zhao, Biao Ma, Hongcheng Cheng, Tian Zhao, Hong Lei, Chenglong Mu, Linbo Chen, Yuanyuan Meng, Jiaojiao Zhang, Yijia Long, Jingyi Su, Guo Chen, Yanjun Li, Gang Hu, Xudong Liao, Quan Chen, Yushan Zhu

eLife. 2022; 11: e81247. Published online 2022 Aug 1. doi: 10.7554/eLife.81247

PMCID:: PMC9377797

Abstract Article PDF–4.9M

Select item 935702312.

USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING

Rebekka Karlowitz, Megan L. Stanifer, Jens Roedig, Geoffroy Andrieux, Denisa Bojkova, Marco Bechtel, Sonja Smith, Lisa Kowald, Ralf Schubert, Melanie Boerries, Jindrich Cinatl, Jr., Steeve Boulant, Sjoerd J. L. van Wijk

Cell Death Dis. 2022 Aug; 13(8): 684. Published online 2022 Aug 6. doi: 10.1038/s41419-022-05124-w

PMCID:: PMC9357023

Abstract Article PDF–3.1M

Select item 934722213.

Immune Evasion and Drug Resistance Mediated by USP22 in Cancer: Novel Targets and Mechanisms

Jinhui Guo, Jie Zhao, Wen Fu, Qiuran Xu, Dongsheng Huang

Front Immunol. 2022; 13: 918314. Published online 2022 Jul 20. doi: 10.3389/fimmu.2022.918314

PMCID:: PMC9347222

Abstract Article PDF–2.6M

Select item 928563714.

USP22 interacts with PALB2 and promotes chemotherapy resistance via homologous recombination of DNA double strand breaks

Isaac K. Nardi, Jeremy M. Stark, Adrien Larsen, Ravi Salgia, Dan J. Raz

Mol Cancer Res. Author manuscript; available in PMC 2022 Jul 15.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 424–435. Published online 2019 Nov 4. doi: 10.1158/1541-7786.MCR-19-0053

PMCID:: PMC9285637

Abstract Article PDF–2.2M

Select item 911973615.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523516.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 902346717.

USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma

Zhen Ning, Xin Guo, Xiaolong Liu, Chang Lu, Aman Wang, Xiaolin Wang, Wen Wang, Huan Chen, Wangshu Qin, Xinyu Liu, Lina Zhou, Chi Ma, Jian Du, Zhikun Lin, Haifeng Luo, Wuxiyar Otkur, Huan Qi, Di Chen, Tian Xia, Jiwei Liu, Guang Tan, Guowang Xu, Hai-long Piao

Nat Commun. 2022; 13: 2187. Published online 2022 Apr 21. doi: 10.1038/s41467-022-29846-9