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Select item 111592041.

Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [¹⁸F]‐2‐fluro‐2‐deoxy‐d‐glucose positron emission tomography

Bishnuhari Paudyal, Noboru Oriuchi, Pramila Paudyal, Tetsuya Higuchi, Takashi Nakajima, Keigo Endo

Cancer Sci. 2008 Feb; 99(2): 260–266. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2007.00683.x

PMCID:: PMC11159204

Abstract Article PDF–185K

Select item 110949512.

CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis

Shao-Kun Yu, Tao Yu, Yu-Ming Wang, Ao Sun, Jia Liu, Kai-Hua Lu

J Transl Med. 2024; 22: 460. Published online 2024 May 15. doi: 10.1186/s12967-024-05284-7

PMCID:: PMC11094951

Abstract Article PDF–4.6M

Select item 107280033.

The knockdown of lncRNA DLGAP1‐AS2 suppresses osteosarcoma progression by inhibiting aerobic glycolysis via the miR‐451a/HK2 axis

Changjun Zheng, Ronghang Li, Shuang Zheng, Hongjuan Fang, Meng Xu, Lei Zhong

Cancer Sci. 2023 Dec; 114(12): 4747–4762. Published online 2023 Oct 10. doi: 10.1111/cas.15989

PMCID:: PMC10728003

Abstract Article PDF–10M

Select item 106176734.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 103904955.

Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2

Yilin Zheng, Yizhi Zhan, Yuqin Zhang, Yaowei Zhang, Yang Liu, Yuwen Xie, Yining Sun, Junying Qian, Yanqing Ding, Yi Ding, Yuan Fang

Cell Death Dis. 2023 Aug; 14(8): 488. Published online 2023 Aug 1. doi: 10.1038/s41419-023-06009-2

PMCID:: PMC10390495

Abstract Article PDF–7.0M

Select item 102911846.

Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion

Jichun Lin, Wenshuo Fang, Zhuo Xiang, Qingqing Wang, Huapeng Cheng, Shimin Chen, Jing Fang, Jia Liu, Qiang Wang, Zhimin Lu, Leina Ma

Front Immunol. 2023; 14: 1189953. Published online 2023 Jun 12. doi: 10.3389/fimmu.2023.1189953

PMCID:: PMC10291184

Abstract Article PDF–6.5M

Select item 102447037.

The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes

Haixia Ma, Valentina Sukonina, Wei Zhang, Fang Meng, Santhilal Subhash, Henrik Palmgren, Ida Alexandersson, Huiming Han, Shuping Zhou, Stefano Bartesaghi, Chandrasekhar Kanduri, Sven Enerbäck

J Biol Chem. 2023 Jun; 299(6): 104795. Published online 2023 May 5. doi: 10.1016/j.jbc.2023.104795

PMCID:: PMC10244703

Abstract Article PDF–3.8M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102367009.

Trigred motif 36 regulates neuroendocrine differentiation of prostate cancer via HK2 ubiquitination and GPx4 deficiency

Xusong Zhao, Tianren Zhou, Yuhao Wang, Meiling Bao, Chenbo Ni, Lei Ding, Shengjie Sun, Huiyu Dong, Jie Li, Chao Liang

Cancer Sci. 2023 Jun; 114(6): 2445–2459. Published online 2023 Mar 6. doi: 10.1111/cas.15763

PMCID:: PMC10236700

Abstract Article PDF–19M

Select item 1014884310.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 1008656211.

High‑risk pathological subtype associated FAM83A‑AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR‑202‑3p/HK2 axis

Xinkui Xiong, Lei Zhang, Bao Zang, Dafu Xu, Chen Chen, Gaochao Dong, Wenjie Xia, Yanhu Wu

Oncol Rep. 2023 May; 49(5): 95. Published online 2023 Mar 22. doi: 10.3892/or.2023.8532

PMCID:: PMC10086562

Abstract Article PDF–5.7M

Select item 1006129212.

L1CAM promotes vasculogenic mimicry formation by miR‐143‐3p‐induced expression of hexokinase 2 in glioma

Yishan Huang, Chenchen Zhu, Pei Liu, Fan Ouyang, Juanjuan Luo, Chunjiao Lu, Bo Tang, Xiaojun Yang

Mol Oncol. 2023 Apr; 17(4): 664–685. Published online 2023 Feb 8. doi: 10.1002/1878-0261.13384

PMCID:: PMC10061292

Abstract Article PDF–14M

Select item 995018313.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 993326914.

Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts

Wenqi Su, Jingwen Li, Lishan Jiang, Lang Lei, Houxuan Li

BMC Oral Health. 2023; 23: 103. Published online 2023 Feb 15. doi: 10.1186/s12903-023-02807-4

PMCID:: PMC9933269

Abstract Article PDF–3.9M

Select item 966287415.

Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer

Jiao Wang, Qiong Huang, Xingbin Hu, Shuyi Zhang, Yu Jiang, Guangyu Yao, Kongzhen Hu, Xin Xu, Bishan Liang, Qijing Wu, Zhenfeng Ma, Yawen Wang, Chunlin Wang, Zhenzhen Wu, Xiaoxiang Rong, Wangjun Liao, Min Shi

Cancer Res. 2022 Apr 15; 82(8): 1503–1517. Published online 2022 Mar 7. doi: 10.1158/0008-5472.CAN-21-1820