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Items: 1 to 20 of 107

1.
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Madeline B. Searcy, Randolph K. Larsen, IV, Bradley T. Stevens, Yang Zhang, Hongjian Jin, Catherine J. Drummond, Casey G. Langdon, Katherine E. Gadek, Kyna Vuong, Kristin B. Reed, Matthew R. Garcia, Beisi Xu, Darden W. Kimbrough, Grace E. Adkins, Nadhir Djekidel, Shaina N. Porter, Patrick A. Schreiner, Shondra M. Pruett-Miller, Brian J. Abraham, Jerold E. Rehg, Mark E. Hatley
Nat Commun. 2023; 14: 7291. Published online 2023 Nov 15. doi: 10.1038/s41467-023-43044-1
PMCID:
PMC10651858
AbstractArticlePDF–7.8M
2.
PAX3 基因新突变致Ⅰ型Waardenburg综合征家系基因型与表型特征分析
李 霞, 赵 声波, 毕 先云, 娄 凡, 曾 文娟, 高 燕, 毛 志勇, 马 静
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Jul 5; 35(7): 621–626. Chinese. doi: 10.13201/j.issn.2096-7993.2021.07.010
PMCID:
PMC10127909
AbstractArticlePDF–6.1M
3.
Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next‐generation sequencing
Chen‐Yu Lee, Ming‐Yu Lo, You‐Mei Chen, Pei‐Hsuan Lin, Chuan‐Jen Hsu, Pei‐Lung Chen, Chen‐Chi Wu, Jacob Shujui Hsu
Mol Genet Genomic Med. 2022 Dec; 10(12): e2082. Published online 2022 Nov 4. doi: 10.1002/mgg3.2082
PMCID:
PMC9747560
AbstractArticlePDF–1009K
4.
The Relationship Between Chimeric RNAs and Gene Fusions; Potential Implications of Reciprocity in Cancer
Justin Elfman, Lam-Phong Pham, Hui Li
J Genet Genomics. Author manuscript; available in PMC 2022 Jul 29.
Published in final edited form as: J Genet Genomics. 2020 Jul 20; 47(7): 341–348. Published online 2020 Jun 14. doi: 10.1016/j.jgg.2020.04.005
PMCID:
PMC9335605
AbstractArticlePDF–790K
5.
Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs
Line Manceau, Julien Richard Albert, Pier-Luigi Lollini, Maxim V. C. Greenberg, Pascale Gilardi-Hebenstreit, Vanessa Ribes
PLoS Genet. 2022 May; 18(5): e1009782. Published online 2022 May 23. doi: 10.1371/journal.pgen.1009782
PMCID:
PMC9166405
AbstractArticlePDF–3.0M
6.
Reduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma
Takuyo Kanayama, Mitsuru Miyachi, Yohei Sugimoto, Shigeki Yagyu, Ken Kikuchi, Kunihiko Tsuchiya, Tomoko Iehara, Hajime Hosoi
Sci Rep. 2021; 11: 18802. Published online 2021 Sep 22. doi: 10.1038/s41598-021-98322-z
PMCID:
PMC8458399
AbstractArticlePDF–1.7M
7.
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Carla Regina, Ebrahem Hamed, Geoffroy Andrieux, Sina Angenendt, Michaela Schneider, Manching Ku, Marie Follo, Marco Wachtel, Eugene Ke, Ken Kikuchi, Anton G Henssen, Beat W Schäfer, Melanie Boerries, Amy J Wagers, Charles Keller, Simone Hettmer
Life Sci Alliance. 2021 Sep; 4(9): e202001002. Published online 2021 Jun 29. doi: 10.26508/lsa.202001002
PMCID:
PMC8321661
AbstractArticlePDF–3.4M
8.
Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer
Doo Byung Chay, Gwan Hee Han, Sanghee Nam, Hanbyoul Cho, Joon-Yong Chung, Stephen M. Hewitt
Int J Clin Oncol. Author manuscript; available in PMC 2021 Jun 7.
Published in final edited form as: Int J Clin Oncol. 2019 Nov; 24(11): 1429–1439. Published online 2019 Jul 13. doi: 10.1007/s10147-019-01507-w
PMCID:
PMC8183735
AbstractArticlePDF–1.3M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
11.
FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.
David Milewski, Samriddhi Shukla, Berkley E. Gryder, Arun Pradhan, Johnny Donovan, Parvathi Sudha, Sushmitha Vallabh, Athena Pyros, Yan Xu, Artem Barski, Sara Szabo, Brian Turpin, Joseph G. Pressey, Douglas P. Millay, Javed Khan, Vladimir V. Kalinichenko, Tanya V. Kalin
Oncogene. Author manuscript; available in PMC 2021 Aug 24.
Published in final edited form as: Oncogene. 2021 Mar; 40(12): 2182–2199. Published online 2021 Feb 24. doi: 10.1038/s41388-021-01694-9
PMCID:
PMC8005492
AbstractArticlePDF–2.8M
12.
PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
Berkley E. Gryder, Marielle E. Yohe, Hsien-Chao Chou, Xiaohu Zhang, Joana Marques, Marco Wachtel, Beat Schaefer, Nirmalya Sen, Young Song, Alberto Gualtieri, Silvia Pomella, Rossella Rota, Abigail Cleveland, Xinyu Wen, Sivasish Sindiri, Jun S. Wei, Frederic G. Barr, Sudipto Das, Thorkell Andresson, Rajarshi Guha, Madhu Lal-Nag, Marc Ferrer, Jack F. Shern, Keji Zhao, Craig J. Thomas, Javed Khan
Cancer Discov. Author manuscript; available in PMC 2021 Jan 12.
Published in final edited form as: Cancer Discov. 2017 Aug; 7(8): 884–899. Published online 2017 Apr 26. doi: 10.1158/2159-8290.CD-16-1297
PMCID:
PMC7802885
AbstractArticlePDF–1.2M
13.
KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma
Lays M. Sobral, Hannah M. Hicks, Janet K. Parrish, Tyler S. McCann, Joseph Hsieh, Andrew Goodspeed, James C. Costello, Joshua C. Black, Paul Jedlicka
Mol Oncol. 2020 Oct; 14(10): 2471–2486. Published online 2020 Aug 5. doi: 10.1002/1878-0261.12769
PMCID:
PMC7530783
AbstractArticlePDF–2.6M
14.
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate
Jamie Zagozewski, Ghazaleh M. Shahriary, Ludivine Coudière Morrison, Olivier Saulnier, Margaret Stromecki, Agnes Fresnoza, Gareth Palidwor, Christopher J. Porter, Antoine Forget, Olivier Ayrault, Cynthia Hawkins, Jennifer A. Chan, Maria C. Vladoiu, Lakshmikirupa Sundaresan, Janilyn Arsenio, Michael D. Taylor, Vijay Ramaswamy, Tamra E. Werbowetski-Ogilvie
Nat Commun. 2020; 11: 3627. Published online 2020 Jul 20. doi: 10.1038/s41467-020-17357-4
PMCID:
PMC7371715
AbstractArticlePDF–10M
15.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
16.
Prognostic implications of forkhead box protein O1 (FOXO1) and paired box 3 (PAX3) in epithelial ovarian cancer
Gwan Hee Han, Doo Byung Chay, Sanghee Nam, Hanbyoul Cho, Joon-Yong Chung, Jae-Hoon Kim
BMC Cancer. 2019; 19: 1202. Published online 2019 Dec 10. doi: 10.1186/s12885-019-6406-6
PMCID:
PMC6905044
AbstractArticlePDF–1.9M
17.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
18.
The PAX3-FOXO1 oncogene alters exosome miRNA content and leads to paracrine effects mediated by exosomal miR-486
Farah Ghamloush, Sandra E. Ghayad, Ghina Rammal, Assil Fahs, Abeer J. Ayoub, Zeina Merabi, Mohamad Harajly, Hassan Zalzali, Raya Saab
Sci Rep. 2019; 9: 14242. Published online 2019 Oct 2. doi: 10.1038/s41598-019-50592-4
PMCID:
PMC6775163
AbstractArticlePDF–4.6M
19.
A novel mutation of the PAX3 gene in a Chinese family with Waardenburg syndrome type I
Jing Ma, Ken Lin, Hong‐chao Jiang, Yanli Yang, Yu Zhang, Guilian Yang, Hao Sun, Cheng Ming, Xianyun Bi, Tiesong Zhang, Biao Ruan
Mol Genet Genomic Med. 2019 Jul; 7(7): e00798. Published online 2019 Jun 12. doi: 10.1002/mgg3.798
PMCID:
PMC6625151
AbstractArticlePDF–1015K
20.
The expression and function of PAX3 in development and disease
Salah Boudjadi, Bishwanath Chatterjee, Wenyue Sun, Prasantha Vemu, Frederic G. Barr
Gene. Author manuscript; available in PMC 2019 Aug 5.
Published in final edited form as: Gene. 2018 Aug 5; 666: 145–157. Published online 2018 May 4. doi: 10.1016/j.gene.2018.04.087
PMCID:
PMC6624083
AbstractArticlePDF–773K

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