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Select item 110826411.

An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation

Chunlin Wang, Maoting Hu, Kunlin Yu, Wuling Liu, Anling Hu, Yi Kuang, Lei Huang, Babu Gajendran, Eldad Zacksenhaus, Xiao Xiao, Yaacov Ben-David

Mol Med Rep. 2024 Jun; 29(6): 107. Published online 2024 Apr 26. doi: 10.3892/mmr.2024.13231

PMCID:: PMC11082641

Abstract Article PDF–4.3M

Select item 109235172.

ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia

Kira Behrens, Natalie Brajanovski, Zhen Xu, Elizabeth M. Viney, Ladina DiRago, Soroor Hediyeh-Zadeh, Melissa J. Davis, Richard B. Pearson, Elaine Sanij, Warren S. Alexander, Ashley P. Ng

Sci Adv. 2024 Mar 8; 10(10): eadj8803. Published online 2024 Mar 8. doi: 10.1126/sciadv.adj8803

PMCID:: PMC10923517

Abstract Article PDF–2.1M

Select item 107044313.

A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells

Benjamin M. Greulich, Saranya Rajendran, Nicholas F. Downing, Taylor R. Nicholas, Peter C. Hollenhorst

J Biol Chem. 2023 Dec; 299(12): 105453. Published online 2023 Nov 11. doi: 10.1016/j.jbc.2023.105453

PMCID:: PMC10704431

Abstract Article PDF–1.3M

Select item 106947804.

V-ets erythroblastosis virus E26 oncogene homolog (avian)/Trefoil factor 3/high-molecular-weight cytokeratin triple immunostain: a novel tissue-based biomarker in prostate cancer with potential clinical application

Kyung Park, Ya-Lin Chiu, Mark A. Rubin, Francesca Demichelis, Juan Miguel Mosquera

Hum Pathol. Author manuscript; available in PMC 2023 Dec 4.

Published in final edited form as: Hum Pathol. 2013 Oct; 44(10): 2282–2292. Published online 2013 Jul 12. doi: 10.1016/j.humpath.2013.05.010

PMCID:: PMC10694780

Abstract Article PDF–3.9M

Select item 105367275.

Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis

Xiaocheng Tang, Jintuan Huang, Yingming Jiang, Jun Qiu, Tuoyang Li, Weiyao Li, Zijian Chen, Zhenze Huang, Xihu Yu, Tao Yang, Xiang Ji, Rongchang Tan, Li lv, Zuli Yang, Hao Chen

J Transl Med. 2023; 21: 670. Published online 2023 Sep 27. doi: 10.1186/s12967-023-04536-2

PMCID:: PMC10536727

Abstract Article PDF–7.9M

Select item 104424586.

ERG Status at the Margin is Associated with Biochemical Recurrence after Radical Prostatectomy with Positive Surgical Margins

Daniela C. Salles, Adrianna A. Mendes, Misop Han, Alan W. Partin, Bruce J. Trock, Yuezhou Jing, Tamara L. Lotan

Mod Pathol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Mod Pathol. 2023 Jul; 36(7): 100147. Published online 2023 Feb 22. doi: 10.1016/j.modpat.2023.100147

PMCID:: PMC10442458

Abstract Article PDF–764K

Select item 104006517.

Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis

Donglin Ding, Alexandra M. Blee, Jianong Zhang, Yunqian Pan, Nicole A. Becker, L. James Maher, 3rd, Rafael Jimenez, Liguo Wang, Haojie Huang

Nat Commun. 2023; 14: 4671. Published online 2023 Aug 3. doi: 10.1038/s41467-023-40352-4

PMCID:: PMC10400651

Abstract Article PDF–3.5M

Select item 103649648.

Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge

Christopher M. Schafer, Silvia Martin-Almedina, Katarzyna Kurylowicz, Neil Dufton, Lourdes Osuna-Almagro, Meng-Ling Wu, Charmain F. Johnson, Aarti V. Shah, Dorian O. Haskard, Andrianna Buxton, Erika Willis, Kate Wheeler, Sean Turner, Magdalena Chlebicz, Rizaldy P. Scott, Susan Kovats, Audrey Cleuren, Graeme M. Birdsey, Anna M. Randi, Courtney T. Griffin

Arterioscler Thromb Vasc Biol. 2023 Aug; 43(8): 1412–1428. Published online 2023 Jun 15. doi: 10.1161/ATVBAHA.123.318926

PMCID:: PMC10364964

Abstract Article PDF–2.7M

Select item 103559459.

Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer

Krassimira Todorova, Metodi V. Metodiev, Gergana Metodieva, Milcho Mincheff, Nelson Fernández, Soren Hayrabedyan

Horm Cancer. 2017 Feb; 8(1): 28–48. Published online 2017 Jan 3. doi: 10.1007/s12672-016-0279-9

PMCID:: PMC10355945

Abstract Article PDF–3.4M

Select item 1023058910.

ERG functionally overlaps with other Ets proteins in promoting T_H9 cell expression of Il9 during allergic lung inflammation

Rakshin Kharwadkar, Benjamin J. Ulrich, Michelle Chu, Byunghee Koh, Matthew M. Hufford, Yongyao Fu, Graeme M. Birdsey, Bo T. Porse, Anna M. Randi, Mark H. Kaplan

J Immunol. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: J Immunol. 2023 Mar 1; 210(5): 537–546. doi: 10.4049/jimmunol.2200113

PMCID:: PMC10230589

Abstract Article PDF–1.6M

Select item 1013986711.

EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment

Yosuke Masamoto, Akira Chiba, Hideaki Mizuno, Toshiya Hino, Hiroki Hayashida, Tomohiko Sato, Masashige Bando, Katsuhiko Shirahige, Mineo Kurokawa

Blood Adv. 2023 Apr 25; 7(8): 1577–1593. Published online 2022 Oct 27. doi: 10.1182/bloodadvances.2022008018

PMCID:: PMC10139867

Abstract Article PDF–1.9M

Select item 934859912.

In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis

Susanne G. Kidd, Mari Bogaard, Kristina T. Carm, Anne Cathrine Bakken, Aase M. V. Maltau, Marthe Løvf, Ragnhild A. Lothe, Karol Axcrona, Ulrika Axcrona, Rolf I. Skotheim

Mol Oncol. 2022 Aug; 16(15): 2810–2822. Published online 2022 Jun 18. doi: 10.1002/1878-0261.13225

PMCID:: PMC9348599

Abstract Article PDF–1.9M

Select item 934857613.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 934647114.

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2‐mediated degradation

Mi Chen, Shreyas Lingadahalli, Nitin Narwade, Kate Man Kei Lei, Shanshan Liu, Zuxianglan Zhao, Yimin Zheng, Qian Lu, Alexander Hin Ning Tang, Terence Chuen Wai Poon, Edwin Cheung

EMBO Rep. 2022 Aug; 23(8): e53468. Published online 2022 Jul 4. doi: 10.15252/embr.202153468

PMCID:: PMC9346471

Abstract Article PDF–5.2M

Select item 910536915.

The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer

Ealia Khosh Kish, Muhammad Choudhry, Yaser Gamallat, Sabrina Marsha Buharideen, Dhananjaya D, Tarek A. Bismar

Int J Mol Sci. 2022 May; 23(9): 4772. Published online 2022 Apr 26. doi: 10.3390/ijms23094772

PMCID:: PMC9105369

Abstract Article PDF–1.0M

Select item 906861116.

PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress

Aiindrila Dhara, Imlimaong Aier, Ankush Paladhi, Pritish Kumar Varadwaj, Sumit Kumar Hira, Nirmalya Sen

Commun Biol. 2022; 5: 416. Published online 2022 May 4. doi: 10.1038/s42003-022-03385-x

PMCID:: PMC9068611

Abstract Article PDF–2.2M

Select item 882889517.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 881540718.

Splice variants denote differences between a cancer stem cell side population of EWSR1-ERG-based Ewing sarcoma cells, its main population and EWSR1-FLI-based cells

Eberhard Korsching, Julian Matschke, Marc Hotfilder

Int J Mol Med. 2022 Mar; 49(3): 39. Published online 2022 Jan 28. doi: 10.3892/ijmm.2022.5094

PMCID:: PMC8815407

Abstract Article PDF–2.8M

Select item 874867519.

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

Hanbing Song, Hannah N. W. Weinstein, Paul Allegakoen, Marc H. Wadsworth, II, Jamie Xie, Heiko Yang, Ethan A. Castro, Kevin L. Lu, Bradley A. Stohr, Felix Y. Feng, Peter R. Carroll, Bruce Wang, Matthew R. Cooperberg, Alex K. Shalek, Franklin W. Huang

Nat Commun. 2022; 13: 141. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27322-4

PMCID:: PMC8748675

Abstract Article PDF–12M

Select item 852943020.

Destruction of DNA‐Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG

Jingwei Shao, Yuqian Yan, Donglin Ding, Dejie Wang, Yundong He, Yunqian Pan, Wei Yan, Anupreet Kharbanda, Hong‐yu Li, Haojie Huang

Adv Sci (Weinh) 2021 Oct; 8(20): 2102555. Published online 2021 Aug 16. doi: 10.1002/advs.202102555

PMCID:: PMC8529430

Abstract Article PDF–5.9M

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