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Select item 109168661.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101838323.

The EGFR phosphatase RPTPγ is a redox‐regulated suppressor of promigratory signaling

Maitreyi S Joshi, Angel Stanoev, Jan Huebinger, Birga Soetje, Veronika Zorina, Lisaweta Roßmannek, Kirsten Michel, Sven AH Müller, Philippe IH Bastiaens

EMBO J. 2023 May; 42(10): e111806. Published online 2023 Mar 29. doi: 10.15252/embj.2022111806

PMCID:: PMC10183832

Abstract Article PDF–3.0M

Select item 95199794.

Loss of RPTPγ primes breast tissue for acid extrusion, promotes malignant transformation and results in early tumour recurrence and shortened survival

Rasmus A. Sloth, Trine V. Axelsen, Maria Sofia Espejo, Nicolai J. Toft, Ninna C. S. Voss, Mark Burton, Mads Thomassen, Pernille Vahl, Ebbe Boedtkjer

Br J Cancer. 2022 Oct 19; 127(7): 1226–1238. Published online 2022 Jul 11. doi: 10.1038/s41416-022-01911-6

PMCID:: PMC9519979

Abstract Article PDF–2.0M

Select item 94564695.

Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG

Giulia Lombardi, Roberta Valeria Latorre, Alessandro Mosca, Diego Calvanese, Luisa Tomasello, Christian Boni, Manuela Ferracin, Massimo Negrini, Nader Al Dewik, Mohamed Yassin, Mohamed A. Ismail, Bruno Carpentieri, Claudio Sorio, Paola Lecca

Int J Mol Sci. 2022 Sep; 23(17): 9899. Published online 2022 Aug 31. doi: 10.3390/ijms23179899

PMCID:: PMC9456469

Abstract Article PDF–4.7M

Select item 87738356.

A Comprehensive Review of Receptor-Type Tyrosine-Protein Phosphatase Gamma (PTPRG) Role in Health and Non-Neoplastic Disease

Christian Boni, Carlo Laudanna, Claudio Sorio

Biomolecules. 2022 Jan; 12(1): 84. Published online 2022 Jan 6. doi: 10.3390/biom12010084

PMCID:: PMC8773835

Abstract Article PDF–1.6M

Select item 87501867.

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells

David A. Merle, Francesca Provenzano, Mohamed Ali Jarboui, Ellen Kilger, Simon J. Clark, Michela Deleidi, Angela Armento, Marius Ueffing

Antioxidants (Basel) 2021 Dec; 10(12): 1944. Published online 2021 Dec 3. doi: 10.3390/antiox10121944

PMCID:: PMC8750186

Abstract Article PDF–2.7M

Select item 85529078.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 83641819.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806510611.

Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients

Mohamed A. Ismail, Marzia Vezzalini, Hisham Morsi, Ahmad Abujaber, Ali Al Sayab, Kodappully Siveen, Mohamed A. Yassin, Maria Monne, Muthanna Samara, Richard Cook, Claudio Sorio, Helmout Modjtahedi, Nader I. Al-Dewik

Sci Rep. 2021; 11: 8833. Published online 2021 Apr 23. doi: 10.1038/s41598-021-86875-y

PMCID:: PMC8065106

Abstract Article PDF–1.9M

Select item 754957412.

Aberrant DNA methylation of PTPRG as one possible mechanism of its under‐expression in CML patients in the State of Qatar

Mohamed A. Ismail, Muthanna Samara, Ali Al Sayab, Mohamed Alsharshani, Mohamed A. Yassin, Govindarajulu Varadharaj, Marzia Vezzalini, Luisa Tomasello, Maria Monne, Hisham Morsi, M. Walid Qoronfleh, Hatem Zayed, Richard Cook, Claudio Sorio, Helmout Modjtahedi, Nader I. Al‐Dewik

Mol Genet Genomic Med. 2020 Oct; 8(10): e1319. Published online 2020 Jul 23. doi: 10.1002/mgg3.1319

PMCID:: PMC7549574

Abstract Article PDF–890K

Select item 754108413.

PTPRG is an ischemia risk locus essential for HCO₃^–-dependent regulation of endothelial function and tissue perfusion

Kristoffer B Hansen, Christian Staehr, Palle D Rohde, Casper Homilius, Sukhan Kim, Mette Nyegaard, Vladimir V Matchkov, Ebbe Boedtkjer

eLife. 2020; 9: e57553. Published online 2020 Sep 21. doi: 10.7554/eLife.57553

PMCID:: PMC7541084

Abstract Article PDF–4.9M

Select item 717763714.

Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia

Luisa Tomasello, Marzia Vezzalini, Christian Boni, Massimiliano Bonifacio, Luigi Scaffidi, Mohamed Yassin, Nader Al-Dewik, Paul Takam Kamga, Mauro Krampera, Claudio Sorio

Int J Mol Sci. 2020 Apr; 21(7): 2298. Published online 2020 Mar 26. doi: 10.3390/ijms21072298

PMCID:: PMC7177637

Abstract Article PDF–2.2M

Select item 698120615.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 653640216.

Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR‐567/PTPRG regulatory pathway

Chengtao Yu, Fang Tian, Jun Liu, Minhui Su, Min Wu, Xuejun Zhu, Wang Qian

Cell Prolif. 2019 May; 52(3): e12610. Published online 2019 Apr 22. doi: 10.1111/cpr.12610

PMCID:: PMC6536402

Abstract Article PDF–2.5M

Select item 648640017.

Genome-wide association study of recurrent early-onset major depressive disorder

J Shi, JB Potash, JA Knowles, MM Weissman, W Coryell, WA Scheftner, WB Lawson, JR DePaulo, Jr., PV Gejman, AR Sanders, JK Johnson, P Adams, S Chaudhury, D Jancic, O Evgrafov, A Zvinyatskovskiy, N Ertman, M Gladis, K Neimanas, M Goodell, N Hale, N Ney, R Verma, D Mirel, P Holmans, DF Levinson

Mol Psychiatry. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Mol Psychiatry. 2011 Feb; 16(2): 193–201. Published online 2010 Feb 2. doi: 10.1038/mp.2009.124

PMCID:: PMC6486400

Abstract Article PDF–1.0M

Select item 638658818.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 616668219.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 607321720.

The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer

Jane Antony, Elisa Zanini, Zoe Kelly, Tuan Zea Tan, Evdoxia Karali, Mohammad Alomary, Youngrock Jung, Katherine Nixon, Paula Cunnea, Christina Fotopoulou, Andrew Paterson, Sushmita Roy‐Nawathe, Gordon B Mills, Ruby Yun‐Ju Huang, Jean Paul Thiery, Hani Gabra, Chiara Recchi

EMBO Rep. 2018 Aug; 19(8): e45670. Published online 2018 Jun 15. doi: 10.15252/embr.201745670

PMCID:: PMC6073217

Abstract Article PDF–7.1M

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