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Select item 109846621.

FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathways

Fung-Yu Huang, Danny Ka-Ho Wong, Lung-Yi Mak, Tan-To Cheung, Sai-Sai Zhang, Hau-Tak Chau, Rex Wan-Hin Hui, Wai-Kay Seto, Man-Fung Yuen

Hepatol Commun. 2023 Dec; 7(12): e0338. Published online 2023 Dec 7. doi: 10.1097/HC9.0000000000000338

PMCID:: PMC10984662

Abstract Article PDF–1.9M

Select item 105431452.

Identification of FAT4 as a positive prognostic biomarker in DLBCL by comprehensive genomic analysis

Liyang Lv, Xiaolong Qi, Chun Wang, Yutong Ma, Yuling Nie, Renaguli Abulaiti, Fang Zhang, Qiping Shi, Zhen Kou, Muhebaier Abuduer, Shunsheng Zhai, Li An, Qin Huang, Zailinuer Gu, Qiuxiang Ou, Hong Liu, Zengsheng Wang, Yang Shao, Zhenzhu Sun, Ling Fu, Xiaomin Wang, Min Mao, Yan Li

Clin Exp Med. 2023; 23(6): 2675–2685. Published online 2023 Feb 22. doi: 10.1007/s10238-023-01018-z

PMCID:: PMC10543145

Abstract Article PDF–4.3M

Select item 99358763.

Structure of the planar cell polarity cadherins Fat4 and Dachsous1

Elliot Medina, Yathreb Easa, Daniel K. Lester, Eric K. Lau, David Sprinzak, Vincent C. Luca

Nat Commun. 2023; 14: 891. Published online 2023 Feb 16. doi: 10.1038/s41467-023-36435-x

PMCID:: PMC9935876

Abstract Article PDF–2.8M

Select item 98834284.

Increased expression of FAT4 suppress metastasis of lung adenocarcinoma through regulating MAPK pathway and associated with immune cells infiltration

Yue Ning, Yang Yang, Hongmei Zheng, Yuting Zhan, Hongjing Zang, Qiuyuan Wen, Jinwu Peng, Songqing Fan

Cancer Med. 2023 Jan; 12(2): 1616–1629. Published online 2022 Jun 30. doi: 10.1002/cam4.4977

PMCID:: PMC9883428

Abstract Article PDF–26M

Select item 94339385.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 94245486.

A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors

Weili Mao, Jiajing Zhou, Jie Hu, Kui Zhao, Zhenling Fu, Jun Wang, Kaili Mao

Front Public Health. 2022; 10: 969070. Published online 2022 Aug 16. doi: 10.3389/fpubh.2022.969070

PMCID:: PMC9424548

Abstract Article PDF–6.2M

Select item 93383137.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 92316238.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 86308279.

FAT4 Identified as a Potential Modifier of Orofacial Cleft Laterality

Sarah W. Curtis, Daniel Chang, Miranda R. Sun, Michael P. Epstein, Jeffrey C. Murray, Eleanor Feingold, Terri H. Beaty, Seth M. Weinberg, Mary L. Marazita, Robert J. Lipinski, Jenna C. Carlson, Elizabeth J. Leslie

Genet Epidemiol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Genet Epidemiol. 2021 Oct; 45(7): 721–735. Published online 2021 Jun 15. doi: 10.1002/gepi.22420

PMCID:: PMC8630827

Abstract Article PDF–1.2M

Select item 836418110.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 760719212.

MiR-106b-5p regulates the migration and invasion of colorectal cancer cells by targeting FAT4

Min Pan, Qiuqiu Chen, Yusong Lu, Feifei Wei, Chunqiao Chen, Guiyan Tang, Hui Huang

Biosci Rep. 2020 Nov 27; 40(11): BSR20200098. Published online 2020 Nov 2. doi: 10.1042/BSR20200098

Expression of Concern in:: Biosci Rep. 2021 Apr 30; 41(4): BSR-20200098_EOC.

PMCID:: PMC7607192

Abstract Article PDF–4.3M

Select item 737678813.

Dchs1-Fat4 regulation of osteogenic differentiation in mouse

Ivan Crespo-Enriquez, Tina Hodgson, Sana Zakaria, Erika Cadoni, Mittal Shah, Stephen Allen, Ayman Al-Khishali, Yaopan Mao, Angela Yiu, Jonna Petzold, Guillermo Villagomez-Olea, Andrew A. Pitsillides, Kenneth D. Irvine, Philippa Francis-West

Development. 2019 Jul 15; 146(14): dev176776. Published online 2019 Jul 29. doi: 10.1242/dev.176776

PMCID:: PMC7376788

Abstract Article

Select item 719712814.

FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

Shika Hanif Malgundkar, Ikram Burney, Mansour Al Moundhri, Moza Al Kalbani, Ritu Lakhtakia, Aikou Okamoto, Yahya Tamimi

BMC Cancer. 2020; 20: 374. Published online 2020 May 4. doi: 10.1186/s12885-020-06900-7

PMCID:: PMC7197128

Abstract Article PDF–1.2M

Select item 668655515.

Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma

Fung-Yu Huang, Danny Ka-Ho Wong, Vivien Wai-Man Tsui, Wai-Kay Seto, Lung-Yi Mak, Tan-To Cheung, Keane K.-Y. Lai, Man-Fung Yuen

BMC Cancer. 2019; 19: 789. Published online 2019 Aug 8. doi: 10.1186/s12885-019-6002-9

PMCID:: PMC6686555

Abstract Article PDF–2.6M

Select item 660091516.

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116

Correction in:: Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.

PMCID:: PMC6600915

Abstract Article PDF–1.7M

Select item 655664117.

FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway

Xiaoxia Che, Fangfang Jian, Nan Jia, Ya Zheng, Yahui Jiang, Weiwei Feng

Am J Transl Res. 2019; 11(5): 2784–2800. Published online 2019 May 15.

PMCID:: PMC6556641

Abstract Article PDF–9.5M

Select item 639996418.

FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

Ran Wei, Yuhong Xiao, Yi Song, Huiping Yuan, Jun Luo, Wei Xu

J Exp Clin Cancer Res. 2019; 38: 112. Published online 2019 Mar 4. doi: 10.1186/s13046-019-1043-0

PMCID:: PMC6399964

Abstract Article PDF–6.3M

Select item 616668219.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 582692620.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

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