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Items: 1 to 20 of 153

1.
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia
Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Mark W. Zimmerman, Thomas Eder, Diaaeldin I. Abdallah, Barbara Maurer, Christina Wagner, Susann Schönefeldt, Katrin Spirk, Alexander Pichler, Tea Pemovska, Carmen Schweicker, Daniel Pölöske, Emina Hubanic, Dennis Jungherz, Tony Andreas Müller, Myint Myat Khine Aung, Anna Orlova, Ha Thi Thanh Pham, Kerstin Zimmel, Thomas Krausgruber, Christoph Bock, Mathias Müller, Maik Dahlhoff, Auke Boersma, Thomas Rülicke, Roman Fleck, Elvin Dominic de Araujo, Patrick Thomas Gunning, Tero Aittokallio, Satu Mustjoki, Takaomi Sanda, Sylvia Hartmann, Florian Grebien, Gregor Hoermann, Torsten Haferlach, Philipp Bernhard Staber, Heidi Anne Neubauer, Alfred Thomas Look, Marco Herling, Richard Moriggl
J Clin Invest. 2024 Apr 15; 134(8): e168536. Published online 2024 Apr 15. doi: 10.1172/JCI168536
PMCID:
PMC11014662
AbstractArticlePDF–9.6M
2.
PAK1 overexpression promotes myxofibrosarcoma angiogenesis through STAT5B-mediated CSF2 transactivation: clinical and therapeutic relevance of amplification and nuclear entry
Chien-Feng Li, Ti-Chun Chan, Fu-Min Fang, Shih-Chen Yu, Hsuan-Ying Huang
Int J Biol Sci. 2023; 19(12): 3920–3936. Published online 2023 Jul 31. doi: 10.7150/ijbs.83467
PMCID:
PMC10411477
AbstractArticlePDF–6.3M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Identification of STAT5B as a biomarker associated with prognosis and immune infiltration in breast cancer
Jiaying Li, Li Li, Gulijiang Mahesutihan, Juanjuan Meng, Yuan Chen, Jingsen Lv
Medicine (Baltimore) 2023 Mar 3; 102(9): e32972. Published online 2023 Mar 3. doi: 10.1097/MD.0000000000032972
PMCID:
PMC9981440
AbstractArticlePDF–1.4M
5.
STAT5b: A master regulator of key biological pathways
Madison R. Smith, Lisa R. Forbes Satter, Alexander Vargas-Hernández
Front Immunol. 2022; 13: 1025373. Published online 2023 Jan 23. doi: 10.3389/fimmu.2022.1025373
PMCID:
PMC9899847
AbstractArticlePDF–1.1M
6.
The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2
Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue
Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600
PMCID:
PMC9475453
AbstractArticlePDF–4.4M
7.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
8.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
9.
STAT3 and STAT5B mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms
Shiqiang Qu, Yujiao Jia, Huijun Wang, Xiaofei Ai, Zefeng Xu, Tiejun Qin, Lijuan Pan, Bing Li, Gang Huang, Robert Peter Gale, Zhijian Xiao
Leuk Lymphoma. Author manuscript; available in PMC 2022 Jun 17.
Published in final edited form as: Leuk Lymphoma. 2021 Jun; 62(6): 1506–1509. Published online 2021 Jan 7. doi: 10.1080/10428194.2020.1869964
PMCID:
PMC9204507
ArticlePDF–527K
10.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
11.
Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia
Dipabarna Bhattacharya, Antonella Teramo, Vanessa Rebecca Gasparini, Jani Huuhtanen, Daehong Kim, Jason Theodoropoulos, Gianluca Schiavoni, Gregorio Barilà, Cristina Vicenzetto, Giulia Calabretto, Monica Facco, Toru Kawakami, Hideyuki Nakazawa, Brunangelo Falini, Enrico Tiacci, Fumihiro Ishida, Gianpietro Semenzato, Tiina Kelkka, Renato Zambello, Satu Mustjoki
Blood Cancer J. 2022 Feb; 12(2): 31. Published online 2022 Feb 24. doi: 10.1038/s41408-022-00630-8
PMCID:
PMC8873566
AbstractArticlePDF–2.4M
12.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
Global proteomics of Ubqln2-based murine models of ALS
Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley
J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960
PMCID:
PMC7873701
AbstractArticlePDF–3.0M
15.
Developmental adaptive immune defects associated with STAT5B deficiency in three young siblings
Corinne L. Foley, Sareea S. Al Remeithi, Christopher T. Towe, Andrew Dauber, Philippe F Backeljauw, Leah Tyzinski, Ashish R. Kumar, Vivian Hwa
J Clin Immunol. Author manuscript; available in PMC 2021 Feb 3.
Published in final edited form as: J Clin Immunol. 2021 Jan; 41(1): 136–146. Published online 2020 Oct 22. doi: 10.1007/s10875-020-00884-6
PMCID:
PMC7854992
AbstractArticlePDF–1.0M
16.
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
Can Küçük, Bei Jiang, Xiaozhou Hu, Wenyan Zhang, John K.C. Chan, Wenming Xiao, Nathan Lack, Can Alkan, John C. Williams, Kendra N. Avery, Pınar Kavak, Anna Scuto, Emel Sen, Philippe Gaulard, Lou Staudt, Javeed Iqbal, Weiwei Zhang, Adam Cornish, Qiang Gong, Qunpei Yang, Hong Sun, Francesco d’Amore, Sirpa Leppä, Weiping Liu, Kai Fu, Laurence de Leval, Timothy McKeithan, Wing C. Chan
Nat Commun. Author manuscript; available in PMC 2020 Dec 16.
Published in final edited form as: Nat Commun. 2015 Jan 14; 6: 6025. Published online 2015 Jan 14. doi: 10.1038/ncomms7025
PMCID:
PMC7743911
AbstractArticlePDF–1.2M
17.
Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker
EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948
PMCID:
PMC7737610
AbstractArticlePDF–3.7M
18.
Human Growth Disorders Associated with Impaired GH action: Defects in STAT5B and JAK2
Vivian Hwa
Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Mol Cell Endocrinol. 2021 Jan 1; 519: 111063. Published online 2020 Oct 27. doi: 10.1016/j.mce.2020.111063
PMCID:
PMC7736371
AbstractArticlePDF–1.0M
19.
Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas
A Nicolae, L Xi, S Pittaluga, Z Abdullaev, SD Pack, J Chen, TA Waldmann, ES Jaffe, M Raffeld
Leukemia. Author manuscript; available in PMC 2020 Nov 30.
Published in final edited form as: Leukemia. 2014 Nov; 28(11): 2244–2248. Published online 2014 Jun 20. doi: 10.1038/leu.2014.200
PMCID:
PMC7701980
ArticlePDF–1.3M
20.
Does acute promyelocytic leukemia patient with the STAT5B/RARa fusion gene respond well to decitabine?: A case report and literature review
Lei Wang, Xiaojing Yan, Juan He
Medicine (Baltimore) 2020 Oct 23; 99(43): e22923. Published online 2020 Oct 23. doi: 10.1097/MD.0000000000022923
PMCID:
PMC7581092
AbstractArticlePDF–322K

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