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Select item 112100801.

PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis

Cheng-Qing Hu, Tao Hou, Rui Xiang, Xin Li, Jing Li, Tian-Tian Wang, Wen-Jun Liu, Song Hou, Di Wang, Qing-He Zhao, Xiao-Xing Yu, Ming Xu, Xing-Kai Liu, Yu-Jing Chi, Ji-Chun Yang

Mil Med Res. 2024; 11: 41. Published online 2024 Jun 27. doi: 10.1186/s40779-024-00543-6

PMCID:: PMC11210080

Abstract Article PDF–25M

Select item 109168662.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 107237363.

Differential activation of mouse and human Panx1 channel variants

Antonio Cibelli, Preeti Dohare, David C. Spray, Eliana Scemes

PLoS One. 2023; 18(12): e0295710. Published online 2023 Dec 15. doi: 10.1371/journal.pone.0295710

PMCID:: PMC10723736

Abstract Article PDF–2.5M

Select item 103804884.

Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and ¹⁰Panx1 Peptides

Alessio Lissoni, Siyu Tao, Rosalie Allewaert, Katja Witschas, Luc Leybaert

Int J Mol Sci. 2023 Jul; 24(14): 11612. Published online 2023 Jul 18. doi: 10.3390/ijms241411612

PMCID:: PMC10380488

Abstract Article PDF–1.4M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 98414456.

Gasdermins and pannexin-1 mediate pathways of chemotherapeutic-induced cell lysis in hematopoietic malignancies

Bowen Zhou, Christopher B. Ryder, George R. Dubyak, Derek W. Abbott

Sci Signal. Author manuscript; available in PMC 2023 Jan 16.

Published in final edited form as: Sci Signal. 2022 Dec 20; 15(765): eabl6781. Published online 2022 Dec 20. doi: 10.1126/scisignal.abl6781

PMCID:: PMC9841445

Abstract Article PDF–1.1M

Select item 98407237.

A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death

Juepu Zhou, Meng Wang, Juan Hu, Zhou Li, Lixia Zhu, Lei Jin

J Assist Reprod Genet. 2023 Jan; 40(1): 65–73. Published online 2022 Dec 5. doi: 10.1007/s10815-022-02666-y

PMCID:: PMC9840723

Abstract Article PDF–1.9M

Select item 96001608.

Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion

Antonio Cibelli, Eliana Scemes, David C. Spray

Cells. 2022 Oct; 11(20): 3219. Published online 2022 Oct 14. doi: 10.3390/cells11203219

PMCID:: PMC9600160

Abstract Article PDF–5.1M

Select item 94567619.

ER-resident STIM1/2 couples Ca²⁺ entry by NMDA receptors to pannexin-1 activation

Chetan S. Patil, Hongbin Li, Natalie E. Lavine, Ruoyang Shi, Ankur Bodalia, Tabrez J. Siddiqui, Michael F. Jackson

Proc Natl Acad Sci U S A. 2022 Sep 6; 119(36): e2112870119. Published online 2022 Aug 29. doi: 10.1073/pnas.2112870119

PMCID:: PMC9456761

Abstract Article PDF–2.2M

Select item 942807210.

A novel heterozygous variant in PANX1 is associated with oocyte death and female infertility

Xing-Wu Wu, Pei-Pei Liu, Yang Zou, Ding-Fei Xu, Zhi-Qin Zhang, Li-Yun Cao, Lu-Fan, Lei-Zhen Xia, Jia-lv Huang, Jia Chen, Cai-Lin Xin, Zhi-Hui Huang, Jun Tan, Qiong-Fang Wu, Zeng-Ming Li

J Assist Reprod Genet. 2022 Aug; 39(8): 1901–1908. Published online 2022 Jul 14. doi: 10.1007/s10815-022-02566-1

PMCID:: PMC9428072

Abstract Article PDF–1.9M

Select item 940920911.

Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells

Sarah Rougé, Sandrine Genetet, Maria Florencia Leal Denis, Michael Dussiot, Pablo Julio Schwarzbaum, Mariano Anibal Ostuni, Isabelle Mouro-Chanteloup

Int J Mol Sci. 2022 Aug; 23(16): 9401. Published online 2022 Aug 20. doi: 10.3390/ijms23169401

PMCID:: PMC9409209

Abstract Article PDF–2.7M

Select item 929169012.

Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release

Min Yuan, Yanxue Yao, Dandan Wu, Chenlu Zhu, Shuying Dong, Xuhui Tong

Cell Cycle. 2022; 21(15): 1651–1661. Published online 2022 Apr 3. doi: 10.1080/15384101.2022.2060655

PMCID:: PMC9291690

Abstract Article PDF–2.8M

Select item 926261413.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 917136114.

Endogenous pannexin1 channels form functional intercellular cell–cell channels with characteristic voltage-dependent properties

Nicolás Palacios-Prado, Paola A. Soto, Ximena López, Eun Ju Choi, Valeria Marquez-Miranda, Maximiliano Rojas, Yorley Duarte, Jinu Lee, Fernando D. González-Nilo, Juan C. Sáez

Proc Natl Acad Sci U S A. 2022 May 3; 119(18): e2202104119. Published online 2022 Apr 29. doi: 10.1073/pnas.2202104119

PMCID:: PMC9171361

Abstract Article PDF–1.7M

Select item 910756715.

Novel insights into the SLC7A11-mediated ferroptosis signaling pathways in preeclampsia patients: identifying pannexin 1 and toll-like receptor 4 as innovative prospective diagnostic biomarkers

Sarah Ragab Abd El-Khalik, Rowida Raafat Ibrahim, Muhammad Tarek Abdel Ghafar, Doaa Shatat, Omnia Safwat El-Deeb

J Assist Reprod Genet. 2022 May; 39(5): 1115–1124. Published online 2022 Mar 24. doi: 10.1007/s10815-022-02443-x

PMCID:: PMC9107567

Abstract Article PDF–905K

Select item 910047116.

Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation

Lisa Maria Metz, Margitta Elvers

Int J Mol Sci. 2022 May; 23(9): 5059. Published online 2022 May 2. doi: 10.3390/ijms23095059

PMCID:: PMC9100471

Abstract Article PDF–4.8M

Select item 893851717.

Endothelial pannexin-1 channels modulate macrophage and smooth muscle cell activation in abdominal aortic aneurysm formation

Amanda C. Filiberto, Michael D. Spinosa, Craig T. Elder, Gang Su, Victoria Leroy, Zachary Ladd, Guanyi Lu, J. Hunter Mehaffey, Morgan D. Salmon, Robert B. Hawkins, Kodi S. Ravichandran, Brant E. Isakson, Gilbert R. Upchurch, Jr, Ashish K. Sharma

Nat Commun. 2022; 13: 1521. Published online 2022 Mar 21. doi: 10.1038/s41467-022-29233-4

PMCID:: PMC8938517

Abstract Article PDF–2.3M

Select item 863229318.

PANX1 is a potential prognostic biomarker associated with immune infiltration in pancreatic adenocarcinoma: A pan-cancer analysis

Lingling Bao, Kai Sun, Xuede Zhang

Channels (Austin) 2021; 15(1): 680–696. Published online 2021 Nov 19. doi: 10.1080/19336950.2021.2004758

PMCID:: PMC8632293

Abstract Article PDF–3.9M

Select item 855290719.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 844067920.

Homozygous variants in PANX1 cause human oocyte death and female infertility

Weijie Wang, Ronggui Qu, Qian Dou, Fengyan Wu, Wenjing Wang, Biaobang Chen, Jian Mu, Zhihua Zhang, Lin Zhao, Zhou Zhou, Jie Dong, Yang Zeng, Ruyi Liu, Jing Du, Shujia Zhu, Qiaoli Li, Lin He, Li Jin, Lei Wang, Qing Sang

Eur J Hum Genet. 2021 Sep; 29(9): 1396–1404. Published online 2021 Jan 25. doi: 10.1038/s41431-020-00807-4