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Select item 109238671.

Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo

Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis, Jr

Nat Commun. 2024; 15: 2142. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46463-w

PMCID:: PMC10923867

Abstract Article PDF–7.3M

Select item 107281942.

Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice

Min Chen, Jie-Ying Zhu, Wang-Jing Mu, Hong-Yang Luo, Yang Li, Shan Li, Lin-Jing Yan, Ruo-Ying Li, Liang Guo

Nat Commun. 2023; 14: 8391. Published online 2023 Dec 18. doi: 10.1038/s41467-023-44242-7

PMCID:: PMC10728194

Abstract Article PDF–8.0M

Select item 103623673.

CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

Florentina Negoita, Alex B. Addinsall, Kristina Hellberg, Conchita Fraguas Bringas, Paul S. Hafen, Tyler J. Sermersheim, Marianne Agerholm, Christopher T.A. Lewis, Danial Ahwazi, Naomi X.Y. Ling, Jeppe K. Larsen, Atul S. Deshmukh, Mohammad A. Hossain, Jonathan S. Oakhill, Julien Ochala, Jeffrey J. Brault, Uma Sankar, David H. Drewry, John W. Scott, Carol A. Witczak, Kei Sakamoto

Mol Metab. 2023 Sep; 75: 101761. Published online 2023 Jun 26. doi: 10.1016/j.molmet.2023.101761

PMCID:: PMC10362367

Abstract Article PDF–3.0M

Select item 102047774.

Calcium/Calmodulin-Dependent Protein Kinase Kinase β (CaMKK β) is Neuroprotective in Stroke in Aged Mice

Lin Liu, Hui Yuan, Kyle Denton, Xue-jun Li, Louise McCullough, Jun Li

Eur J Neurosci. Author manuscript; available in PMC 2023 May 23.

Published in final edited form as: Eur J Neurosci. 2016 Aug; 44(4): 2139–2146. doi: 10.1111/ejn.13299

PMCID:: PMC10204777

Abstract Article PDF–1.2M

Select item 100721815.

CaMKK2 Knockout Bone Marrow Cells Collected/Processed in Low Oxygen (Physioxia) Suggests CaMKK2 as a Hematopoietic Stem to Progenitor Differentiation Fate Determinant

Hal E. Broxmeyer, James Ropa, Maegan L. Capitano, Scott Cooper, Luigi Racioppi, Uma Sankar

Stem Cell Rev Rep. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Stem Cell Rev Rep. 2022 Oct; 18(7): 2513–2521. Published online 2022 Mar 9. doi: 10.1007/s12015-021-10306-8

PMCID:: PMC10072181

Abstract Article PDF–800K

Select item 100031516.

Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin

Justin N. Williams, Mavis Irwin, Yong Li, Anuradha Valiya Kambrath, Brett T. Mattingly, Sheel Patel, Mizuho Kittaka, Rebecca N. Collins, Nicholas A. Clough, Emma H. Doud, Amber L. Mosley, Teresita Bellido, Angela Bruzzaniti, Lilian I. Plotkin, Jonathan C. Trinidad, William R. Thompson, Lynda F. Bonewald, Uma Sankar

Int J Mol Sci. 2023 Mar; 24(5): 4718. Published online 2023 Mar 1. doi: 10.3390/ijms24054718

PMCID:: PMC10003151

Abstract Article PDF–9.4M

Select item 98129067.

Increased CaMKK2 expression is an adaptive response that maintains the fitness of tumor-infiltrating natural killer cells

Patrick K. Juras, Luigi Racioppi, Debarati Mukherjee, Sandeep Artham, Xia Gao, Laura Akullian D’Agostino, Ching-Yi Chang, Donald P. McDonnell

Cancer Immunol Res. Author manuscript; available in PMC 2023 Jul 3.

Published in final edited form as: Cancer Immunol Res. 2023 Jan 3; 11(1): 109–122. doi: 10.1158/2326-6066.CIR-22-0391

PMCID:: PMC9812906

Abstract Article PDF–1.0M

Select item 95848158.

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin

Nat Metab. 2022; 4(10): 1369–1401. Published online 2022 Oct 10. doi: 10.1038/s42255-022-00640-7

PMCID:: PMC9584815

Abstract Article PDF–9.0M

Select item 93433549.

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis, Jr, So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Marc Foretz, Benoit Viollet, Reuben Shaw, Andrew Sproul, Franck Polleux

Nat Commun. 2022; 13: 4444. Published online 2022 Aug 1. doi: 10.1038/s41467-022-32130-5

PMCID:: PMC9343354

Abstract Article PDF–8.1M

Select item 924302810.

LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response

Sandy MacMillan, Andrew P. Holmes, Mark L. Dallas, Amira D. Mahmoud, Michael J. Shipston, Chris Peers, D. Grahame Hardie, Prem Kumar, A. Mark Evans

Commun Biol. 2022; 5: 642. Published online 2022 Jun 29. doi: 10.1038/s42003-022-03583-7

Correction in:: Commun Biol. 2022; 5: 765.

PMCID:: PMC9243028

Abstract Article PDF–2.4M

Select item 922154511.

Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer

Thomas L. Pulliam, Dominik Awad, Jenny J. Han, Mollianne M. Murray, Jeffrey J. Ackroyd, Pavithr Goli, Jonathan S. Oakhill, John W. Scott, Michael M. Ittmann, Daniel E. Frigo

Cells. 2022 Jun; 11(12): 1890. Published online 2022 Jun 10. doi: 10.3390/cells11121890

PMCID:: PMC9221545

Abstract Article PDF–4.7M

Select item 916979812.

A molecular complex of Ca_v1.2/CaMKK2/CaMK1a in caveolae is responsible for vascular remodeling via excitation–transcription coupling

Yoshiaki Suzuki, Takumi Ozawa, Tomo Kurata, Nanami Nakajima, Gerald W. Zamponi, Wayne R. Giles, Yuji Imaizumi, Hisao Yamamura

Proc Natl Acad Sci U S A. 2022 Apr 19; 119(16): e2117435119. Published online 2022 Apr 11. doi: 10.1073/pnas.2117435119

PMCID:: PMC9169798

Abstract Article PDF–2.8M

Select item 915756113.

Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism

Brittany A. Stork, Adam Dean, Andrea R. Ortiz, Pradip Saha, Nagireddy Putluri, Maricarmen D. Planas-Silva, Iqbal Mahmud, Kimal Rajapakshe, Cristian Coarfa, Stefan Knapp, Philip L. Lorenzi, Bruce E. Kemp, Benjamin E. Turk, John W. Scott, Anthony R. Means, Brian York

Mol Metab. 2022 Aug; 62: 101513. Published online 2022 May 11. doi: 10.1016/j.molmet.2022.101513

PMCID:: PMC9157561

Abstract Article PDF–3.0M

Select item 901569914.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 881003915.

microRNA-378b regulates ethanol-induced hepatic steatosis by targeting CaMKK2 to mediate lipid metabolism

Ying-Zhao Wang, Jun Lu, Yuan-Yuan Li, Yu-Juan Zhong, Cheng-Fang Yang, Yan Zhang, Li-Hua Huang, Su-Mei Huang, Qi-Ran Li, Dan Wu, Meng-Wei Song, Lin Shi, Li Li, Yong-Wen Li

Bioengineered. 2021; 12(2): 12659–12676. Published online 2021 Dec 20. doi: 10.1080/21655979.2021.2003677

PMCID:: PMC8810039

Abstract Article PDF–4.8M

Select item 879060016.

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

Jun Seok Son, Song Ah Chae, Liang Zhao, Hongyang Wang, Jeanene M. de Avila, Mei-Jun Zhu, Zhihua Jiang, Min Du

EBioMedicine. 2022 Feb; 76: 103842. Published online 2022 Jan 23. doi: 10.1016/j.ebiom.2022.103842

PMCID:: PMC8790600

Abstract Article PDF–4.3M

Select item 854626617.

Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells

Wei Huang, Yaping Liu, Anthony Luz, Mark Berrong, Joel N. Meyer, Yujing Zou, Excel Swann, Pasupathi Sundaramoorthy, Yubin Kang, Shekeab Jauhari, William Lento, Nelson Chao, Luigi Racioppi

Front Immunol. 2021; 12: 754083. Published online 2021 Oct 12. doi: 10.3389/fimmu.2021.754083

PMCID:: PMC8546266

Abstract Article PDF–6.0M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 725191320.

CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis

Mohammad Golam Sabbir

Cell Commun Signal. 2020; 18: 80. Published online 2020 May 27. doi: 10.1186/s12964-020-00575-0

PMCID:: PMC7251913

Abstract Article PDF–8.0M

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PMC Links for GEO Profiles (Select 89521781) (64)
PMC
Conserved Domain Links for Protein (Select 1827361142) (1)
Conserved Domains
PREDICTED: Mus musculus N-deacetylase/N-sulfotransferase (heparan glucosaminyl) ...
PREDICTED: Mus musculus N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 (Ndst3), transcript variant X6, mRNA
gi|1907152647|ref|XM_036163424.1|

Nucleotide
PREDICTED: Mus musculus N-deacetylase/N-sulfotransferase (heparan glucosaminyl) ...
PREDICTED: Mus musculus N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 (Ndst3), transcript variant X7, mRNA
gi|1039765490|ref|XM_006502376.3|

Nucleotide
PREDICTED: Mus musculus protein kinase inhibitor beta, cAMP dependent, testis sp...
PREDICTED: Mus musculus protein kinase inhibitor beta, cAMP dependent, testis specific (Pkib), transcript variant X4, mRNA
gi|1907074009|ref|XM_006512605.5|

Nucleotide

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