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Items: 1 to 20 of 74

1.
Loss of Uncoupling Protein 1 Expression in the Subcutaneous Adipose Tissue Predicts Childhood Obesity
Katalin Gyurina, Mariia Yarmak, László Sasi-Szabó, Sarolta Molnár, Gábor Méhes, Tamás Röszer
Int J Mol Sci. 2023 Dec; 24(23): 16706. Published online 2023 Nov 24. doi: 10.3390/ijms242316706
PMCID:
PMC10706300
AbstractArticlePDF–22M
2.
Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease
Claudia Huesca-Gómez, Yazmín Estela Torres-Paz, Giovanny Fuentevilla-Álvarez, Nadia Janet González-Moyotl, Edgar Samuel Ramírez-Marroquín, Xicótencatl Vásquez-Jiménez, Víctor Sainz-Escarrega, María Elena Soto, Reyna Samano, Ricardo Gamboa
Arch Endocrinol Metab. 2023 Mar-Apr; 67(2): 214–223. Published online 2023 Jan 17. doi: 10.20945/2359-3997000000582
PMCID:
PMC10689038
AbstractArticlePDF–311K
3.
Structural basis of purine nucleotide inhibition of human uncoupling protein 1
Scott A. Jones, Prerana Gogoi, Jonathan J. Ruprecht, Martin S. King, Yang Lee, Thomas Zögg, Els Pardon, Deepak Chand, Stefan Steimle, Danielle M. Copeman, Camila A. Cotrim, Jan Steyaert, Paul G. Crichton, Vera Moiseenkova-Bell, Edmund R. S. Kunji
Sci Adv. 2023 Jun 2; 9(22): eadh4251. Published online 2023 May 31. doi: 10.1126/sciadv.adh4251
PMCID:
PMC10413660
AbstractArticlePDF–1.1M
4.
Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia
Alena A. Nikanorova, Nikolay A. Barashkov, Vera G. Pshennikova, Nyurgun N. Gotovtsev, Georgii P. Romanov, Aisen V. Solovyev, Sargylana S. Kuzmina, Nikolay N. Sazonov, Sardana A. Fedorova
Genes (Basel) 2022 Sep; 13(9): 1612. Published online 2022 Sep 8. doi: 10.3390/genes13091612
PMCID:
PMC9498418
AbstractArticlePDF–1.8M
5.
Chronic Fatty Acid Depletion Induces Uncoupling Protein 1 (UCP1) Expression to Coordinate Mitochondrial Inducible Proton Leak in a Human-Brown-Adipocyte Model
Yukimasa Takeda, Ping Dai
Cells. 2022 Jul; 11(13): 2038. Published online 2022 Jun 27. doi: 10.3390/cells11132038
PMCID:
PMC9265531
AbstractArticlePDF–6.6M
6.
Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis
Riccardo Cavalieri, Marlou Klein Hazebroek, Camila A. Cotrim, Yang Lee, Edmund R.S. Kunji, Martin Jastroch, Susanne Keipert, Paul G. Crichton
Mol Metab. 2022 Aug; 62: 101526. Published online 2022 Jun 9. doi: 10.1016/j.molmet.2022.101526
PMCID:
PMC9243162
AbstractArticlePDF–1.4M
7.
Mitochondrial Protein UCP1 Inhibits the Malignant Behaviors of Triple-negative Breast Cancer through Activation of Mitophagy and Pyroptosis
Jing Xia, Changbin Chu, Wanqing Li, Hong Chen, Wenhua Xie, Rui Cheng, Kai Hu, Xi Li
Int J Biol Sci. 2022; 18(7): 2949–2961. Published online 2022 Apr 18. doi: 10.7150/ijbs.68438
PMCID:
PMC9066108
AbstractArticlePDF–3.2M
8.
UCP1 modulates immune infiltration level and survival outcome in ovarian cancer patients
Jinfa Huang, Guilian Wang, Kedan Liao, Ning Xie, Kaixian Deng
J Ovarian Res. 2022; 15: 16. Published online 2022 Jan 28. doi: 10.1186/s13048-022-00951-z
PMCID:
PMC8800348
AbstractArticlePDF–2.2M
9.
Macrophages expressing uncoupling protein 1 increase in adipose tissue in response to cold in humans
Brian S. Finlin, Hasiyet Memetimin, Amy L. Confides, Beibei Zhu, Philip M. Westgate, Esther E. Dupont-Versteegden, Philip A. Kern
Sci Rep. 2021; 11: 23598. Published online 2021 Dec 8. doi: 10.1038/s41598-021-03014-3
PMCID:
PMC8655049
AbstractArticlePDF–2.2M
10.
Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis
Rong Huang, Tingting Cai, Yunting Zhou, Yuming Wang, Huiying Wang, Ziyang Shen, Wenqing Xia, Xiaomei Liu, Bo Ding, Yong Luo, Rengna Yan, Huiqin Li, Jindan Wu, Jianhua Ma
Biomed Res Int. 2021; 2021: 3482879. Published online 2021 Oct 19. doi: 10.1155/2021/3482879
PMCID:
PMC8548105
AbstractArticlePDF–748K
11.
Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2
D. Halbgebauer, J. Roos, J.B. Funcke, H. Neubauer, B.S. Hamilton, E. Simon, E.Z. Amri, K.M. Debatin, M. Wabitsch, P. Fischer-Posovszky, D. Tews
Mol Metab. 2021 Nov; 53: 101336. Published online 2021 Sep 1. doi: 10.1016/j.molmet.2021.101336
PMCID:
PMC8456047
AbstractArticlePDF–2.0M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
The Role of Nonshivering Thermogenesis Genes on Leptin Levels Regulation in Residents of the Coldest Region of Siberia
Alena A. Nikanorova, Nikolay A. Barashkov, Vera G. Pshennikova, Sergey S. Nakhodkin, Nyurgun N. Gotovtsev, Georgii P. Romanov, Aisen V. Solovyev, Sargylana S. Kuzmina, Nikolay N. Sazonov, Sardana A. Fedorova
Int J Mol Sci. 2021 May; 22(9): 4657. Published online 2021 Apr 28. doi: 10.3390/ijms22094657
PMCID:
PMC8124869
AbstractArticlePDF–1.8M
14.
NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue
María Bové, Fermi Monto, Paloma Guillem-Llobat, M Dolores Ivorra, M Antonia Noguera, Andrea Zambrano, M Salome Sirerol-Piquer, Ana Cristina Requena, Mauricio García-Alonso, Teresa Tejerina, José T. Real, Isabel Fariñas, Pilar D’Ocon
Front Endocrinol (Lausanne) 2021; 12: 630097. Published online 2021 Mar 18. doi: 10.3389/fendo.2021.630097
PMCID:
PMC8015941
AbstractArticlePDF–6.5M
15.
IRX3 Overexpression Enhances Ucp1 Expression In Vivo
Zhiyin Zhang, Qihan Wu, Yang He, Peng Lu, Danjie Li, Minglan Yang, Weiqiong Gu, Ruixin Liu, Jie Hong, Jiqiu Wang
Front Endocrinol (Lausanne) 2021; 12: 634191. Published online 2021 Mar 10. doi: 10.3389/fendo.2021.634191
PMCID:
PMC7988233
AbstractArticlePDF–3.0M
16.
Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis
Xujia Liu, Zehua Jiang, Guihua Zhang, Tsz Kin Ng, Zhenggen Wu
BMC Ophthalmol. 2021; 21: 81. Published online 2021 Feb 12. doi: 10.1186/s12886-021-01838-1
PMCID:
PMC7881628
AbstractArticlePDF–1.9M
17.
Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation
Laurent Vergnes, Jason Y. Lin, Graeme R. Davies, Christopher D. Church, Karen Reue
J Biol Chem. 2020 Oct 30; 295(44): 15054–15069. Published online 2020 Aug 27. doi: 10.1074/jbc.RA120.013322
PMCID:
PMC7606676
AbstractArticlePDF–4.4M
18.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
19.
Increased Risk of High Body Fat and Altered Lipid Metabolism Associated to Suboptimal Consumption of Vitamin A Is Modulated by Genetic Variants rs5888 (SCARB1), rs1800629 (UCP1) and rs659366 (UCP2)
Sebastià Galmés, Andreu Palou, Francisca Serra
Nutrients. 2020 Sep; 12(9): 2588. Published online 2020 Aug 26. doi: 10.3390/nu12092588
PMCID:
PMC7551832
AbstractArticlePDF–2.0M
20.
Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases
Anna E. Pravednikova, Sergey Y. Shevchenko, Victor V. Kerchev, Manana R. Skhirtladze, Svetlana N. Larina, Zaur M. Kachaev, Alexander D. Egorov, Yulii V. Shidlovskii
Mol Med. 2020; 26: 51. Published online 2020 May 25. doi: 10.1186/s10020-020-00180-4
PMCID:
PMC7249395
AbstractArticlePDF–1.3M

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