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Items: 1 to 20 of 40

1.
ATG16L1 WD40 domain-dependent IL10R (interleukin 10 receptor) signaling is insensitive to the T300A Crohn disease risk polymorphism
Inmaculada Serramito-Gómez, Elena Terraza-Silvestre, Álvaro Fernández-Cabrera, Raquel Villamuera, Felipe X. Pimentel-Muiños
Autophagy. 2022; 18(12): 3023–3030. Published online 2022 Mar 29. doi: 10.1080/15548627.2022.2054241
PMCID:
PMC9673950
AbstractArticlePDF–1.4M
2.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
3.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
4.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
5.
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity
Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang
Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8
PMCID:
PMC8956604
AbstractArticlePDF–3.9M
6.
Dcf1 induces glioblastoma cells apoptosis by blocking autophagy
Guanghong Luo, Ruili Feng, Wengang Li, Yanlu Chen, Yangyang Sun, Junfeng Ma, Yanhong Duo, Tieqiao Wen
Cancer Med. 2022 Jan; 11(1): 207–223. Published online 2021 Nov 19. doi: 10.1002/cam4.4440
PMCID:
PMC8704163
AbstractArticlePDF–1.7M
7.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
8.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1
Daniel Hamaoui, Mathilde M. Cossé, Jagan Mohan, Alf Håkon Lystad, Thomas Wollert, Agathe Subtil
Proc Natl Acad Sci U S A. 2020 Oct 27; 117(43): 26784–26794. Published online 2020 Oct 14. doi: 10.1073/pnas.2005389117
PMCID:
PMC7604492
AbstractArticlePDF–1.5M
11.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
12.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
13.
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer
Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen
Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938
PMCID:
PMC6504119
AbstractArticlePDF–1.3M
14.
Dendritic cell factor 1 inhibits proliferation and migration and induces apoptosis of neuroblastoma cells by inhibiting the ERK signaling pathway
Guanghong Luo, Ruili Feng, Yangyang Sun, Lili Zheng, Yajiang Wang, Yanlu Chen, Tieqiao Wen
Oncol Rep. 2019 Jan; 41(1): 103–112. Published online 2018 Oct 16. doi: 10.3892/or.2018.6796
PMCID:
PMC6278510
AbstractArticlePDF–1.0M
15.
TMEM59 potentiates Wnt signaling by promoting signalosome formation
Jan P. Gerlach, Ingrid Jordens, Daniele V. F. Tauriello, Ineke van ‘t Land-Kuper, Jeroen M. Bugter, Ivar Noordstra, Johanneke van der Kooij, Teck Y. Low, Felipe X. Pimentel-Muiños, Despina Xanthakis, Nicola Fenderico, Catherine Rabouille, Albert J. R. Heck, David A. Egan, Madelon M. Maurice
Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): E3996–E4005. Published online 2018 Apr 9. doi: 10.1073/pnas.1721321115
PMCID:
PMC5924918
AbstractArticlePDF–1.4M
16.
Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells
Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo
Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31
PMCID:
PMC5839158
AbstractArticlePDF–1.9M
17.
The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion
M Swayampakula, P C McDonald, M Vallejo, E Coyaud, S C Chafe, A Westerback, G Venkateswaran, J Shankar, G Gao, E M N Laurent, Y Lou, K L Bennewith, C T Supuran, I R Nabi, B Raught, S Dedhar
Oncogene. 2017 Nov 9; 36(45): 6244–6261. Published online 2017 Jul 10. doi: 10.1038/onc.2017.219
PMCID:
PMC5684442
AbstractArticlePDF–4.4M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
19.
The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1
Emilio Boada-Romero, Inmaculada Serramito-Gómez, María P. Sacristán, David L. Boone, Ramnik J. Xavier, Felipe X. Pimentel-Muiños
Nat Commun. 2016; 7: 11821. Published online 2016 Jun 8. doi: 10.1038/ncomms11821
PMCID:
PMC4899871
AbstractArticlePDF–1.3M
20.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M

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