PMC Links for GEO Profiles (Select 90198684) - PMC

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 80649814.

Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction

Thomas M. Hofbauer, Andreas Mangold, Anna S. Ondracek, Adelheid Panzenböck, Thomas Scherz, Julian Müller, Klaus Distelmaier, Veronika Seidl, Stefan Kastl, Martina Müller-Nurasyid, Annette Peters, Konstantin Strauch, Robert Winker, Evelyne Wohlschläger-Krenn, Sonja Nistler, Irene M. Lang

Basic Res Cardiol. 2021; 116(1): 29. Published online 2021 Apr 23. doi: 10.1007/s00395-021-00864-w

PMCID:: PMC8064981

Abstract Article PDF–938K

Select item 76071805.

AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response

Yujia Xia, Jiayi He, Hongji Zhang, Han Wang, George Tetz, Casey A. Maguire, Yu Wang, Amblessed Onuma, Dmitry Genkin, Victor Tetz, Alexey Stepanov, Stanislav Terekhov, Valeria Ukrainskaya, Hai Huang, Allan Tsung

Mol Oncol. 2020 Nov; 14(11): 2920–2935. Published online 2020 Sep 5. doi: 10.1002/1878-0261.12787

PMCID:: PMC7607180

Abstract Article PDF–4.2M

Select item 67544526.

Evaluation of the functional effects of genetic variants‒missense and nonsense SNPs, indels and copy number variations‒in the gene encoding human deoxyribonuclease I potentially implicated in autoimmunity

Misuzu Ueki, Kaori Kimura-Kataoka, Junko Fujihara, Reiko Iida, Yasuyuki Kawai, Akari Kusaka, Takamitsu Sasaki, Haruo Takeshita, Toshihiro Yasuda

Sci Rep. 2019; 9: 13660. Published online 2019 Sep 20. doi: 10.1038/s41598-019-49935-y

PMCID:: PMC6754452

Abstract Article PDF–1.1M

Select item 56785817.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 56089408.

Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung

Paul T. King, Roleen Sharma, Kim M. O’Sullivan, Judy Callaghan, Lovisa Dousha, Belinda Thomas, Saleela Ruwanpura, Steven Lim, Michael W. Farmer, Barton R. Jennings, Michaela Finsterbusch, Gavin Brooks, Stavros Selemidis, Gary P. Anderson, Stephen R. Holdsworth, Philip G. Bardin

Sci Rep. 2017; 7: 12128. Published online 2017 Sep 21. doi: 10.1038/s41598-017-12474-5

PMCID:: PMC5608940

Abstract Article PDF–3.0M

Select item 51024969.

Single Nucleotide Polymorphisms in the BDNF, VDR, and DNASE 1 Genes in Dry Eye Disease Patients: A Case-Control Study

Joelle A. Hallak, Sapna Tibrewal, Neil Mohindra, Xiaoyi Gao, Sandeep Jain

Invest Ophthalmol Vis Sci. 2015 Sep; 56(10): 5990–5996. Published online 2015 Sep 22. doi: 10.1167/iovs.15-17036

PMCID:: PMC5102496

Abstract Article PDF–290K

Select item 487854610.

DNase I aggravates islet β-cell apoptosis in type 2 diabetes

BIN ZHU, LEI ZHANG, YUE-YING ZHANG, LEI WANG, XIN-GANG LI, TENG LIU, YU-KE FU, YAN-FEI ZHENG, PING LI, ZHI-GANG ZHAO

Mol Med Rep. 2016 Jun; 13(6): 4577–4584. Published online 2016 Apr 11. doi: 10.3892/mmr.2016.5102

PMCID:: PMC4878546

Abstract Article PDF–1.3M

Select item 446597511.

TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form

Dhivya Thiyagarajan, Ole Petter Rekvig, Natalya Seredkina

PLoS One. 2015; 10(6): e0129485. Published online 2015 Jun 11. doi: 10.1371/journal.pone.0129485

PMCID:: PMC4465975

Abstract Article PDF–4.4M

Select item 411726612.

Identification of the Functional Alleles of the Nonsynonymous Single-Nucleotide Polymorphisms Potentially Implicated in Systemic Lupus Erythematosus in the Human Deoxyribonuclease I Gene

Kaori Kimura-Kataoka, Misuzu Ueki, Haruo Takeshita, Junko Fujihara, Reiko Iida, Yasuyuki Kawai, Toshihiro Yasuda

DNA Cell Biol. 2014 Aug 1; 33(8): 492–502. doi: 10.1089/dna.2014.2368

PMCID:: PMC4117266

Abstract Article PDF–344K

Select item 377350513.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 331660814.

Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e

Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper, Christopher Graham Fenton, Ole Petter Rekvig, Elin Synnøve Mortensen

PLoS One. 2012; 7(3): e34080. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0034080

PMCID:: PMC3316608

Abstract Article PDF–2.3M

Select item 318839215.

Induction and Maintenance of IL-4 Expression Are Regulated Differently by the 3′ Enhancer in CD4 T Cells

M. Hanief Sofi, Yu Qiao, K. Mark Ansel, Masato Kubo, Cheong-Hee Chang

J Immunol. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: J Immunol. 2011 Mar 1; 186(5): 2792–2799. Published online 2011 Jan 31. doi: 10.4049/jimmunol.1003353

PMCID:: PMC3188392

Abstract Article PDF–1.5M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516817.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 293837018.

Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis

Svetlana N. Zykova, Anders A. Tveita, Ole Petter Rekvig

PLoS One. 2010; 5(8): e12096. Published online 2010 Aug 10. doi: 10.1371/journal.pone.0012096

PMCID:: PMC2938370

Abstract Article PDF–2.8M

Select item 290683019.

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Abdul Hakkim, Barbara G. Fürnrohr, Kerstin Amann, Britta Laube, Ulrike Abu Abed, Volker Brinkmann, Martin Herrmann, Reinhard E. Voll, Arturo Zychlinsky

Proc Natl Acad Sci U S A. 2010 May 25; 107(21): 9813–9818. Published online 2010 May 3. doi: 10.1073/pnas.0909927107

PMCID:: PMC2906830

Abstract Article PDF–653K

Select item 277583220.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

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