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Select item 92098111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 75074022.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Jason Zi Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.8M

Select item 71456833.

Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio

Tobias T Schmidt, Sushma Sharma, Gloria X Reyes, Anna Kolodziejczak, Tina Wagner, Brian Luke, Anders Hofer, Andrei Chabes, Hans Hombauer

Nucleic Acids Res. 2020 Jan 10; 48(1): 264–277. Published online 2019 Oct 24. doi: 10.1093/nar/gkz1006

PMCID:: PMC7145683

Abstract Article PDF–3.9M

Select item 60634374.

Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae

Norah Owiti, Shanqiao Wei, Ashok S. Bhagwat, Nayun Kim

PLoS Genet. 2018 Jul; 14(7): e1007516. Published online 2018 Jul 17. doi: 10.1371/journal.pgen.1007516

PMCID:: PMC6063437

Abstract Article PDF–5.7M

Select item 59402125.

Gene dosage effects in yeast support broader roles for the LOG1, HAM1 and DUT1 genes in detoxification of nucleotide analogues

Mattias Carlsson, Guo-Zhen Hu, Hans Ronne

PLoS One. 2018; 13(5): e0196840. Published online 2018 May 8. doi: 10.1371/journal.pone.0196840

PMCID:: PMC5940212

Abstract Article PDF–28M

Select item 56618856.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 56480327.

Architecture and dynamics of overlapped RNA regulatory networks

Christopher P. Lapointe, Melanie A. Preston, Daniel Wilinski, Harriet A.J. Saunders, Zachary T. Campbell, Marvin Wickens

RNA. 2017 Nov; 23(11): 1636–1647. doi: 10.1261/rna.062687.117

PMCID:: PMC5648032

Abstract Article PDF–6.6M

Select item 47189228.

Systematic humanization of yeast genes reveals conserved functions and genetic modularity

Aashiq H. Kachroo, Jon M. Laurent, Christopher M. Yellman, Austin G. Meyer, Claus O. Wilke, Edward M. Marcotte

Science. Author manuscript; available in PMC 2016 Jan 20.

Published in final edited form as: Science. 2015 May 22; 348(6237): 921–925. doi: 10.1126/science.aaa0769

PMCID:: PMC4718922

Abstract Article PDF–2.0M

Select item 47079529.

Protein-RNA networks revealed through covalent RNA marks

Christopher P. Lapointe, Daniel Wilinski, Harriet A. J. Saunders, Marvin Wickens

Nat Methods. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Nat Methods. 2015 Dec; 12(12): 1163–1170. Published online 2015 Nov 2. doi: 10.1038/nmeth.3651

PMCID:: PMC4707952

Abstract Article PDF–856K

Select item 470301210.

Target selection by natural and redesigned PUF proteins

Douglas F. Porter, Yvonne Y. Koh, Brett VanVeller, Ronald T. Raines, Marvin Wickens

Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52): 15868–15873. Published online 2015 Dec 14. doi: 10.1073/pnas.1508501112

PMCID:: PMC4703012

Abstract Article PDF–1.3M

Select item 467129111.

Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme

Anatoli Tchigvintsev, Alexander U. Singer, Robert Flick, Pierre Petit, Greg Brown, Elena Evdokimova, Alexei Savchenko, Alexander F. Yakunin

Biochem J. Author manuscript; available in PMC 2015 Dec 7.

Published in final edited form as: Biochem J. 2011 Jul 15; 437(2): 243–253. doi: 10.1042/BJ20110304

PMCID:: PMC4671291

Abstract Article PDF–1.5M

Select item 464965012.

Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants

Akil Hamza, Erik Tammpere, Megan Kofoed, Christelle Keong, Jennifer Chiang, Guri Giaever, Corey Nislow, Philip Hieter

Genetics. 2015 Nov; 201(3): 1263–1274. Published online 2015 Sep 9. doi: 10.1534/genetics.115.181099

PMCID:: PMC4649650

Abstract Article PDF–6.2M

Select item 356498713.

Saccharomyces cerevisiae Genetics Predicts Candidate Therapeutic Genetic Interactions at the Mammalian Replication Fork

Derek M. van Pel, Peter C. Stirling, Sean W. Minaker, Payal Sipahimalani, Philip Hieter

G3 (Bethesda) 2013 Feb; 3(2): 273–282. Published online 2013 Feb 1. doi: 10.1534/g3.112.004754

PMCID:: PMC3564987

Abstract Article PDF–2.3M

Select item 355349714.

The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis

Felix Willmund, Marta del Alamo, Sebastian Pechmann, Taotao Chen, Veronique Albanese, Eric B. Dammer, Junmin Peng, Judith Frydman

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2013 Jan 17; 152(1-2): 196–209. doi: 10.1016/j.cell.2012.12.001

PMCID:: PMC3553497

Abstract Article PDF–5.1M

Select item 322764215.

Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90

Eric A. Franzosa, Véronique Albanèse, Judith Frydman, Yu Xia, Amie J. McClellan

PLoS One. 2011; 6(11): e28211. Published online 2011 Nov 30. doi: 10.1371/journal.pone.0028211

PMCID:: PMC3227642

Abstract Article PDF–1.7M

Select item 312543916.

An integrated approach to characterize genetic interaction networks in yeast metabolism

Balázs Szappanos, Károly Kovács, Béla Szamecz, Frantisek Honti, Michael Costanzo, Anastasia Baryshnikova, Gabriel Gelius-Dietrich, Martin J. Lercher, Márk Jelasity, Chad L. Myers, Brenda J. Andrews, Charles Boone, Stephen G. Oliver, Csaba Pál, Balázs Papp

Nat Genet. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Nat Genet. 2011 Jul; 43(7): 656–662. Published online 2011 May 29. doi: 10.1038/ng.846

PMCID:: PMC3125439

Abstract Article PDF–2.5M

Select item 309130117.

Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins

Tanja Scherrer, Christian Femmer, Ralph Schiess, Ruedi Aebersold, André P Gerber

Genome Biol. 2011; 12(1): R3. Published online 2011 Jan 13. doi: 10.1186/gb-2011-12-1-r3

PMCID:: PMC3091301

Abstract Article PDF–1.3M

Select item 308252418.

Homologous Recombination Is Stimulated by a Decrease in dUTPase in Arabidopsis

Emeline Dubois, Dolores Córdoba-Cañero, Sophie Massot, Nicolas Siaud, Bertrand Gakière, Séverine Domenichini, Florence Guérard, Teresa Roldan-Arjona, Marie-Pascale Doutriaux

PLoS One. 2011; 6(4): e18658. Published online 2011 Apr 26. doi: 10.1371/journal.pone.0018658

PMCID:: PMC3082524

Abstract Article PDF–877K

Select item 307093819.

Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes

Joseph Fasolo, Andrea Sboner, Mark G.F. Sun, Haiyuan Yu, Rui Chen, Donald Sharon, Philip M. Kim, Mark Gerstein, Michael Snyder

Genes Dev. 2011 Apr; 25(7): 767–778. doi: 10.1101/gad.1998811

PMCID:: PMC3070938

Abstract Article PDF–1.2M

Select item 285666620.

Functional Organization of the S. cerevisiae Phosphorylation Network

Dorothea Fiedler, Hannes Braberg, Monika Mehta, Gal Chechik, Gerard Cagney, Paromita Mukherjee, Andrea C. Silva, Michael Shales, Sean R. Collins, Sake van Wageningen, Patrick Kemmeren, Frank C. P. Holstege, Jonathan S. Weissman, Michael-Christopher Keogh, Daphne Koller, Kevan M. Shokat, Nevan J. Krogan

Cell. Author manuscript; available in PMC 2010 Apr 19.

Published in final edited form as: Cell. 2009 Mar 6; 136(5): 952–963. doi: 10.1016/j.cell.2008.12.039

PMCID:: PMC2856666

Abstract Article PDF–3.9M

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