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Select item 98363481.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 92098112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 88076393.

Peroxisomal ATP Uptake Is Provided by Two Adenine Nucleotide Transporters and the ABCD Transporters

Carlo W. T. van Roermund, Lodewijk IJlst, Nicole Linka, Ronald J. A. Wanders, Hans R. Waterham

Front Cell Dev Biol. 2021; 9: 788921. Published online 2022 Jan 19. doi: 10.3389/fcell.2021.788921

PMCID:: PMC8807639

Abstract Article PDF–1.1M

Select item 62157134.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 59225285.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

Select item 56618856.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 56002547.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 46160398.

Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

Christopher J. Kershaw, Joseph L. Costello, David Talavera, William Rowe, Lydia M. Castelli, Paul F. G. Sims, Christopher M. Grant, Mark P. Ashe, Simon J. Hubbard, Graham D. Pavitt

Sci Rep. 2015; 5: 15518. Published online 2015 Oct 23. doi: 10.1038/srep15518

PMCID:: PMC4616039

Abstract Article PDF–2.2M

Select item 41320659.

Involvement of the Carboxyl-Terminal Region of the Yeast Peroxisomal Half ABC Transporter Pxa2p in Its Interaction with Pxa1p and in Transporter Function

Cheng-Yi Chuang, Ling-Yun Chen, Ru-Huei Fu, Shih-Ming Chen, Ming-Hua Ho, Jie-Mau Huang, Chia-Chi Hsu, Chien-Cheng Wang, Meng-Shian Chen, Rong-Tzong Tsai

PLoS One. 2014; 9(8): e104892. Published online 2014 Aug 13. doi: 10.1371/journal.pone.0104892

PMCID:: PMC4132065

Abstract Article PDF–5.0M

Select item 383549210.

Mapping the functional yeast ABC transporter interactome

Jamie Snider, Asad Hanif, Mid Eum Lee, Ke Jin, Analyn R. Yu, Chris Graham, Matthew Chuk, Dunja Damjanovic, Marta Wierzbicka, Priscilla Tang, Dina Balderes, Victoria Wong, Matthew Jessulat, Katelyn D. Darowski, Bryan-Joseph San Luis, Igor Shevelev, Stephen L Sturley, Charles Boone, Jack F. Greenblatt, Zhaolei Zhang, Christian M. Paumi, Mohan Babu, Hay-Oak Park, Susan Michaelis, Igor Stagljar

Nat Chem Biol. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Nat Chem Biol. 2013 Sep; 9(9): 565–572. Published online 2013 Jul 7. doi: 10.1038/nchembio.1293

PMCID:: PMC3835492

Abstract Article PDF–1.2M

Select item 354253011.

Targeted proteomics reveals compositional dynamics of 60S pre-ribosomes after nuclear export

Martin Altvater, Yiming Chang, Andre Melnik, Laura Occhipinti, Sabina Schütz, Ute Rothenbusch, Paola Picotti, Vikram Govind Panse

Mol Syst Biol. 2012; 8: 628. Published online 2012 Dec 4. doi: 10.1038/msb.2012.63

PMCID:: PMC3542530

Abstract Article PDF–3.8M

Select item 353790812.

Global Analysis of Yeast mRNPs

Sarah F. Mitchell, Saumya Jain, Meipei She, Roy Parker

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Nat Struct Mol Biol. 2013 Jan; 20(1): 127–133. Published online 2012 Dec 9. doi: 10.1038/nsmb.2468

PMCID:: PMC3537908

Abstract Article PDF–1.2M

Select item 353328613.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo A. Sukhai, Swayam Prabha, Rose Hurren, Angela C. Rutledge, Anna Y. Lee, Shrivani Sriskanthadevan, Hong Sun, Xiaoming Wang, Marko Skrtic, Ayesh Seneviratne, Maria Cusimano, Bozhena Jhas, Marcela Gronda, Neil MacLean, Eunice E. Cho, Paul A. Spagnuolo, Sumaiya Sharmeen, Marinella Gebbia, Malene Urbanus, Kolja Eppert, Dilan Dissanayake, Alexia Jonet, Alexandra Dassonville-Klimpt, Xiaoming Li, Alessandro Datti, Pamela S. Ohashi, Jeff Wrana, Ian Rogers, Pascal Sonnet, William Y. Ellis, Seth J. Corey, Connie Eaves, Mark D. Minden, Jean C.Y. Wang, John E. Dick, Corey Nislow, Guri Giaever, Aaron D. Schimmer

J Clin Invest. 2013 Jan 2; 123(1): 315–328. Published online 2012 Dec 3. doi: 10.1172/JCI64180

PMCID:: PMC3533286

Abstract Article PDF–2.1M

Select item 351004414.

The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing

Erica A. Moehle, Colm J. Ryan, Nevan J. Krogan, Tracy L. Kress, Christine Guthrie

PLoS Genet. 2012 Nov; 8(11): e1003101. Published online 2012 Nov 29. doi: 10.1371/journal.pgen.1003101

PMCID:: PMC3510044

Abstract Article PDF–3.4M

Select item 337019715.

Peroxisomal Fatty Acid Uptake Mechanism in Saccharomyces cerevisiae

Carlo W. T. van Roermund, Lodewijk IJlst, Wiktor Majczak, Hans R. Waterham, Hendrik Folkerts, Ronald J. A. Wanders, Klaas J. Hellingwerf

J Biol Chem. 2012 Jun 8; 287(24): 20144–20153. Published online 2012 Apr 9. doi: 10.1074/jbc.M111.332833

PMCID:: PMC3370197

Abstract Article PDF–1.1M

Select item 331716016.

Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs

Sara Sharifpoor, Dewald van Dyk, Michael Costanzo, Anastasia Baryshnikova, Helena Friesen, Alison C. Douglas, Ji-Young Youn, Benjamin VanderSluis, Chad L. Myers, Balázs Papp, Charles Boone, Brenda J. Andrews

Genome Res. 2012 Apr; 22(4): 791–801. doi: 10.1101/gr.129213.111

PMCID:: PMC3317160

Abstract Article PDF–998K

Select item 327939317.

Analysis of yeast endocytic site formation and maturation through a regulatory transition point

Susheela Y. Carroll, Helen E. M. Stimpson, Jasper Weinberg, Christopher P. Toret, Yidi Sun, David G. Drubin

Mol Biol Cell. 2012 Feb 15; 23(4): 657–668. doi: 10.1091/mbc.E11-02-0108

Correction in:: Mol Biol Cell. 2012 Aug 15; 23(16): 3275.

PMCID:: PMC3279393

Abstract Article PDF–3.2M

Select item 319815618.

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

Suzanne Hoppins, Sean R. Collins, Ann Cassidy-Stone, Eric Hummel, Rachel M. DeVay, Laura L. Lackner, Benedikt Westermann, Maya Schuldiner, Jonathan S. Weissman, Jodi Nunnari

J Cell Biol. 2011 Oct 17; 195(2): 323–340. doi: 10.1083/jcb.201107053

PMCID:: PMC3198156

Abstract Article PDF–4.1M

Select item 312543919.

An integrated approach to characterize genetic interaction networks in yeast metabolism

Balázs Szappanos, Károly Kovács, Béla Szamecz, Frantisek Honti, Michael Costanzo, Anastasia Baryshnikova, Gabriel Gelius-Dietrich, Martin J. Lercher, Márk Jelasity, Chad L. Myers, Brenda J. Andrews, Charles Boone, Stephen G. Oliver, Csaba Pál, Balázs Papp

Nat Genet. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Nat Genet. 2011 Jul; 43(7): 656–662. Published online 2011 May 29. doi: 10.1038/ng.846

PMCID:: PMC3125439

Abstract Article PDF–2.5M

Select item 294328120.

The Arabidopsis Peroxisomal ABC Transporter, Comatose, Complements the Saccharomyces cerevisiae pxa1 pxa2Δ Mutant for Metabolism of Long-chain Fatty Acids and Exhibits Fatty Acyl-CoA-stimulated ATPase Activity

Yvonne Nyathi, Carine De Marcos Lousa, Carlo W. van Roermund, Ronald J. A. Wanders, Barbara Johnson, Stephen A. Baldwin, Frederica L. Theodoulou, Alison Baker

J Biol Chem. 2010 Sep 24; 285(39): 29892–29902. Published online 2010 Jul 21. doi: 10.1074/jbc.M110.151225

PMCID:: PMC2943281

Abstract Article PDF–1.1M

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