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Items: 1 to 20 of 23

1.
Overexpression of miR-375 and L-type Amino Acid Transporter 1 in Pheochromocytoma and Their Molecular and Functional Implications
Jacopo Manso, Loris Bertazza, Susi Barollo, Alberto Mondin, Simona Censi, Sofia Carducci, Alfonso Massimiliano Ferrara, Isabella Merante Boschin, Stefania Zovato, Francesca Schiavi, Michele Gregianin, Gianmaria Pennelli, Maurizio Iacobone, Caterina Mian
Int J Mol Sci. 2022 Mar; 23(5): 2413. Published online 2022 Feb 22. doi: 10.3390/ijms23052413
PMCID:
PMC8910416
AbstractArticlePDF–955K
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Molecular recognition of physiological substrate noradrenaline by the adrenaline synthesising enzyme PNMT and factors influencing its methyltransferase activity
Nyssa Drinkwater, Christine L. Gee, Munish Puri, Kevin R. Criscione, Michael J. McLeish, Gary L. Grunewald, Jennifer L. Martin
Biochem J. Author manuscript; available in PMC 2018 May 8.
Published in final edited form as: Biochem J. 2009 Aug 27; 422(3): 463–471. Published online 2009 Aug 27. doi: 10.1042/BJ20090702
PMCID:
PMC5940352
AbstractArticlePDF–1.5M
4.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
5.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
6.
Phenylethanolamine N-methyltransferase downregulation is associated with malignant pheochromocytoma/paraganglioma
Seung Eun Lee, Ensel Oh, Boram Lee, Yu Jin Kim, Doo-Yi Oh, Kyungsoo Jung, Jong-Sun Choi, Junghan Kim, Sung Joo Kim, Jung Wook Yang, Jungsuk An, Young Lyun Oh, Yoon-La Choi
Oncotarget. 2016 Apr 26; 7(17): 24141–24153. Published online 2016 Mar 21. doi: 10.18632/oncotarget.8234
PMCID:
PMC5029690
AbstractArticlePDF–6.3M
7.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
8.
Kinetic and pH Studies on Human Phenylethanolamine N-Methyltransferase
Qian Wu, Michael J. McLeish
Arch Biochem Biophys. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Arch Biochem Biophys. 2013 Nov 1; 539(1): 10.1016/j.abb.2013.08.019. Published online 2013 Sep 7. doi: 10.1016/j.abb.2013.08.019
PMCID:
PMC3853373
AbstractArticlePDF–1.3M
9.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
10.
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Carl A. Anderson, Gabrielle Boucher, Charlie W. Lees, Andre Franke, Mauro D’Amato, Kent D. Taylor, James C. Lee, Philippe Goyette, Marcin Imielinski, Anna Latiano, Caroline Lagacé, Regan Scott, Leila Amininejad, Suzannah Bumpstead, Leonard Baidoo, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Büning, Jean-Frédéric Colombel, Lee A. Denson, Martine De Vos, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Rudolf S.N. Fehrmann, James A.B. Floyd, Tim Florin, Denis Franchimont, Lude Franke, Michel Georges, Jürgen Glas, Nicole L. Glazer, Stephen L. Guthery, Talin Haritunians, Nicholas K. Hayward, Jean-Pierre Hugot, Gilles Jobin, Debby Laukens, Ian Lawrance, Marc Lémann, Arie Levine, Cecile Libioulle, Edouard Louis, Dermot P. McGovern, Monica Milla, Grant W. Montgomery, Katherine I. Morley, Craig Mowat, Aylwin Ng, William Newman, Roel A Ophoff, Laura Papi, Orazio Palmieri, Laurent Peyrin-Biroulet, Julián Panés, Anne Phillips, Natalie J. Prescott, Deborah D. Proctor, Rebecca Roberts, Richard Russell, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Philip Schumm, Frank Seibold, Yashoda Sharma, Lisa Simms, Mark Seielstad, A. Hillary Steinhart, Stephan R. Targan, Leonard H. van den Berg, Morten Vatn, Hein Verspaget, Thomas Walters, Cisca Wijmenga, David C. Wilson, Harm-Jan Westra, Ramnik J. Xavier, Zhen Z. Zhao, Cyriel Y. Ponsioen, Vibeke Andersen, Leif Torkvist, Maria Gazouli, Nicholas P. Anagnou, Tom H. Karlsen, Limas Kupcinskas, Jurgita Sventoraityte, John C. Mansfield, Subra Kugathasan, Mark S. Silverberg, Jonas Halfvarson, Jerome I. Rotter, Christopher G. Mathew, Anne M. Griffiths, Richard Gearry, Tariq Ahmad, Steven R. Brant, Mathias Chamaillard, Jack Satsangi, Judy H. Cho, Stefan Schreiber, Mark J. Daly, Jeffrey C. Barrett, Miles Parkes, Vito Annese, Hakon Hakonarson, Graham Radford-Smith, Richard H. Duerr, Séverine Vermeire, Rinse K. Weersma, John D. Rioux
Nat Genet. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: Nat Genet. 2011 Mar; 43(3): 246–252. Published online 2011 Feb 6. doi: 10.1038/ng.764
Correction in:
volume 43 on page 919
PMCID:
PMC3084597
AbstractArticlePDF–404K
11.
Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells
Ok-Hee Lee, Hyeung Kim, Quanyuan He, Hwa Jin Baek, Dong Yang, Liuh-Yow Chen, Jiancong Liang, Heekyung Kate Chae, Amin Safari, Dan Liu, Zhou Songyang
Mol Cell Proteomics. 2011 Feb; 10(2): M110.001628. Published online 2010 Nov 11. doi: 10.1074/mcp.M110.001628
PMCID:
PMC3033672
AbstractArticlePDF–1.5M
12.
Association Study of 182 Candidate Genes in Anorexia Nervosa
Andrea Poyastro Pinheiro, Cynthia M. Bulik, Laura M. Thornton, Patrick F. Sullivan, Tammy L. Root, Cinnamon S. Bloss, Wade H. Berrettini, Nicholas J. Schork, Walter H. Kaye, Andrew W. Bergen, Pierre Magistretti, Harry Brandt, Steve Crawford, Scott Crow, Manfred M. Fichter, David Goldman, Katherine A. Halmi, Craig Johnson, Allan S. Kaplan, Pamela K. Keel, Kelly L. Klump, Maria La Via, James E. Mitchell, Michael Strober, Alessandro Rotondo, Janet Treasure, D. Blake Woodside
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Oct 25.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5): 1070–1080. doi: 10.1002/ajmg.b.31082
PMCID:
PMC2963154
AbstractArticlePDF–315K
13.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
14.
Phenylethanolamine N-Methyltransferase Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury
Ahsan Alam, Daniel T. O’Connor, Mary C. Perianayagam, Alexey Y. Kolyada, Yuqing Chen, Fangwen Rao, Manjula Mahata, Sushil Mahata, Orfeas Liangos, Bertrand L. Jaber
Nephron Clin Pract. 2010 Apr; 114(4): c253–c259. Published online 2010 Jan 20. doi: 10.1159/000276577
PMCID:
PMC2865401
AbstractArticlePDF–128K
15.
Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach
Juan L. Rodríguez-Flores, Kuixing Zhang, Sun Woo Kang, Gen Wen, Sajalendu Ghosh, Ryan S. Friese, Sushil K. Mahata, Shankar Subramaniam, Bruce A. Hamilton, Daniel T. O’Connor
Mamm Genome. 2010; 21(3): 195–204. Published online 2010 Mar 5. doi: 10.1007/s00335-010-9253-y
PMCID:
PMC2844968
AbstractArticlePDF–479K
16.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
17.
The Reaction Mechanism of Phenylethanolamine N-Methyltransferase: A Density Functional Theory Study
Polina Georgieva, Qian Wu, Michael J. McLeish, Fahmi Himo
Biochim Biophys Acta. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Dec; 1794(12): 1831–1837. Published online 2009 Sep 3. doi: 10.1016/j.bbapap.2009.08.022
PMCID:
PMC2760686
AbstractArticlePDF–2.4M
18.
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
Robert D Oades, Jessica Lasky-Su, Hanna Christiansen, Stephen V Faraone, Edmund JS Sonuga-Barke, Tobias Banaschewski, Wai Chen, Richard JL Anney, Jan K Buitelaar, Richard P Ebstein, Barbara Franke, Michael Gill, Ana Miranda, Herbert Roeyers, Aribert Rothenberger, Joseph A Sergeant, Hans-Christoph Steinhausen, Eric A Taylor, Margaret Thompson, Philip Asherson
Behav Brain Funct. 2008; 4: 48. Published online 2008 Oct 20. doi: 10.1186/1744-9081-4-48
PMCID:
PMC2577091
AbstractArticlePDF–367K
19.
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer
P R Benusiglio, P D Pharoah, P L Smith, F Lesueur, D Conroy, R N Luben, G Dew, C Jordan, A Dunning, D F Easton, B A J Ponder
Br J Cancer. 2006 Dec 18; 95(12): 1689–1695. Published online 2006 Nov 21. doi: 10.1038/sj.bjc.6603473
PMCID:
PMC2360759
AbstractArticlePDF–114K
20.
Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1
Katrin Kepp, Peeter Juhanson, Viktor Kozich, Mai Ots, Margus Viigimaa, Maris Laan
BMC Med Genet. 2007; 8: 47. Published online 2007 Jul 23. doi: 10.1186/1471-2350-8-47
PMCID:
PMC1947951
AbstractArticlePDF–571K

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