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Items: 1 to 20 of 162

1.
CARM1 hypermethylates the NuRD chromatin remodeling complex to promote cell cycle gene expression and breast cancer development
Xue Chen, Ming-feng Huang, Da-meng Fan, Yao-hui He, Wen-juan Zhang, Jian-cheng Ding, Bing-ling Peng, Xu Pan, Ya Liu, Jun Du, Ying Li, Zhi-ying Liu, Bing-lan Xie, Zhi-jian Kuang, Jia Yi, Wen Liu
Nucleic Acids Res. 2024 Jul 8; 52(12): 6811–6829. Published online 2024 Apr 27. doi: 10.1093/nar/gkae329
PMCID:
PMC11229315
AbstractArticlePDF–5.6M
2.
Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1
Rahma F. Hayati, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Lin Zhao, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani
Genes (Basel) 2024 Jun; 15(6): 698. Published online 2024 May 27. doi: 10.3390/genes15060698
PMCID:
PMC11202806
AbstractArticlePDF–1.7M
3.
Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity
Hidehiro Itonaga, Adnan K. Mookhtiar, Sarah M. Greenblatt, Fan Liu, Concepcion Martinez, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma C. Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas, Luca Tottone, Tulasigeri Totiger, Terrence Bradley, Justin Taylor, Stephan Schürer, Stephen D. Nimer
Nat Commun. 2024; 15: 3415. Published online 2024 Apr 22. doi: 10.1038/s41467-024-47689-4
PMCID:
PMC11035800
AbstractArticlePDF–6.5M
4.
Inhibition of CARM1 suppresses proliferation of multiple myeloma cells through activation of p53 signaling pathway
Lan Yang, Le Ma, Qiang Gong, JiePing Chen, Qilin Huang
Mol Biol Rep. 2023; 50(9): 7457–7469. Published online 2023 Jul 21. doi: 10.1007/s11033-023-08645-5
PMCID:
PMC10460731
AbstractArticlePDF–8.9M
5.
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
Yi Zhong, Yilong Wang, Xiaoguang Li, Haojie Qin, Shu Yan, Caijun Rao, Di Fan, Duqiu Liu, Fei Deng, Yanli Miao, Ling Yang, Kai Huang
Diabetes. 2023 Aug; 72(8): 1095–1111. Published online 2023 May 22. doi: 10.2337/db22-1016
PMCID:
PMC10382653
AbstractArticlePDF–42M
6.
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity
Guillem Torcal Garcia, Elisabeth Kowenz-Leutz, Tian V Tian, Antonis Klonizakis, Jonathan Lerner, Luisa De Andres-Aguayo, Valeriia Sapozhnikova, Clara Berenguer, Marcos Plana Carmona, Maria Vila Casadesus, Romain Bulteau, Mirko Francesconi, Sandra Peiro, Philipp Mertins, Kenneth Zaret, Achim Leutz, Thomas Graf
eLife. 2023; 12: e83951. Published online 2023 Jun 27. doi: 10.7554/eLife.83951
PMCID:
PMC10299824
AbstractArticlePDF–7.2M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
9.
CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β: CDKN2AIP inhibits the progression of seminoma
Yuming Cao, Zhenlie Chen, Zihan Qin, Kaiyu Qian, Tongzu Liu, Yuanzhen Zhang
Acta Biochim Biophys Sin (Shanghai) 2022 May; 54(5): 604–614. Published online 2022 May 18. doi: 10.3724/abbs.2022040
PMCID:
PMC9909323
AbstractArticlePDF–30M
10.
ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer
Hyuntae Im, Hee‐ji Baek, Eunbi Yang, Kyeongkyu Kim, Se Kyu Oh, Jung‐Shin Lee, Hyunkyung Kim, Ji Min Lee
Cancer Sci. 2023 Jan; 114(1): 187–200. Published online 2022 Oct 1. doi: 10.1111/cas.15595
PMCID:
PMC9807526
AbstractArticlePDF–7.6M
11.
LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML
Qian Chen, Murat A. Cevher, Qi Jiang, Saisai Wang, Xiaojian Sun, Robert G. Roeder, Mo Chen
Proc Natl Acad Sci U S A. 2022 Oct 18; 119(42): e2213718119. Published online 2022 Oct 10. doi: 10.1073/pnas.2213718119
PMCID:
PMC9586329
AbstractArticlePDF–1.8M
12.
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang
Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x
PMCID:
PMC9523997
AbstractArticlePDF–6.9M
13.
Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis
Yandong Lai, Xiuying Li, Tiao Li, Xiaoyun Li, Toru Nyunoya, Kong Chen, Georgios Kitsios, Mehdi Nouraie, Yingze Zhang, Bryan J McVerry, Janet S Lee, Rama K Mallmapalli, Chunbin Zou
Thorax. 2023 Apr; 78(4): 383–393. Published online 2022 Mar 30. doi: 10.1136/thoraxjnl-2021-217526
PMCID:
PMC9522923
AbstractArticlePDF–8.5M
14.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
15.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
PMCID:
PMC9440653
AbstractArticlePDF–2.9M
16.
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours
Hong-feng Yuan, Man Zhao, Li-na Zhao, Hao-lin Yun, Guang Yang, Yu Geng, Yu-fei Wang, Wei Zheng, Ying Yuan, Tian-qiang Song, Jun-qi Niu, Xiao-dong Zhang
Acta Pharmacol Sin. 2022 Sep; 43(9): 2373–2385. Published online 2022 Jan 19. doi: 10.1038/s41401-021-00841-y
PMCID:
PMC9433386
AbstractArticlePDF–6.6M
17.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
18.
SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication
Hainan Liu, Yu Bai, Xun Zhang, Ting Gao, Yue Liu, Entao Li, Xuefeng Wang, Zheng Cao, Lin Zhu, Qincai Dong, Yong Hu, Guangfei Wang, Caiwei Song, Xiayang Niu, Tong Zheng, Di Wang, Zijing Liu, Yanwen Jin, Ping Li, Xiuwu Bian, Cheng Cao, Xuan Liu
J Virol. 2022 Jun; 96(12): e00412-22. Published online 2022 Jun 2. doi: 10.1128/jvi.00412-22
PMCID:
PMC9215227
AbstractArticlePDF–4.2M
19.
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Nat Commun. 2022; 13: 3181. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30794-7
PMCID:
PMC9177965
AbstractArticlePDF–2.2M
20.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M

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