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Select item 111054651.

PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues

Marcin Sajek, Damian Mikolaj Janecki, Maciej Jerzy Smialek, Barbara Ginter-Matuszewska, Anna Spik, Slawomir Oczkowski, Erkut Ilaslan, Kamila Kusz-Zamelczyk, Maciej Kotecki, Jacek Blazewicz, Jadwiga Jaruzelska

Cell Mol Life Sci. 2019 Jan; 76(1): 147–161. Published online 2018 Sep 29. doi: 10.1007/s00018-018-2926-5

PMCID:: PMC11105465

Abstract Article PDF–1.6M

Select item 110728872.

PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression

Xin Li, Mengyi Zhu, Min Zang, Dandan Cao, Zhengyao Xie, Haibo Liang, Zexin Bian, Tingting Zhao, Zhibin Hu, Eugene Yujun Xu

Cell Mol Life Sci. 2022 May; 79(5): 279. Published online 2022 May 4. doi: 10.1007/s00018-022-04254-w

PMCID:: PMC11072887

Abstract Article PDF–11M

Select item 108150463.

A Circular RNA Derived from the Pumilio 1 Gene Could Regulate PTEN in Human Cumulus Cells

Angela Caponnetto, Carmen Ferrara, Anna Fazzio, Noemi Agosta, Marianna Scribano, Maria Elena Vento, Placido Borzì, Cristina Barbagallo, Michele Stella, Marco Ragusa, Paolo Scollo, Davide Barbagallo, Michele Purrello, Cinzia Di Pietro, Rosalia Battaglia

Genes (Basel) 2024 Jan; 15(1): 124. Published online 2024 Jan 19. doi: 10.3390/genes15010124

PMCID:: PMC10815046

Abstract Article PDF–2.6M

Select item 105206434.

PUM1 Promotes Tumor Progression by Activating DEPTOR‐Meditated Glycolysis in Gastric Cancer

Songcheng Yin, Huifang Liu, Zhijun Zhou, Xiaoyu Xu, Pengliang Wang, Wei Chen, Guofei Deng, Han Wang, Hong Yu, Liang Gu, Mingyu Huo, Min Li, Leli Zeng, Yulong He, Changhua Zhang

Adv Sci (Weinh) 2023 Sep; 10(27): 2301190. Published online 2023 Jul 19. doi: 10.1002/advs.202301190

PMCID:: PMC10520643

Abstract Article PDF–6.8M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101586246.

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen

FASEB Bioadv. 2023 May; 5(5): 183–198. Published online 2023 Feb 21. doi: 10.1096/fba.2022-00115

PMCID:: PMC10158624

Abstract Article PDF–7.2M

Select item 99501837.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 99224688.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 97696989.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 970808610.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 969993911.

PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin

Reem Elagooz, Anita R. Dhara, Rose M. Gott, Sarah E. Adams, Rachael A. White, Arnab Ghosh, Shinjini Ganguly, Yuncheng Man, Amma Owusu-Ansah, Omar Y. Mian, Umut A. Gurkan, Anton A. Komar, Mahesh Ramamoorthy, Merlin Nithya Gnanapragasam

Blood Adv. 2022 Dec 13; 6(23): 6016–6022. Published online 2022 Jun 8. doi: 10.1182/bloodadvances.2021006730

PMCID:: PMC9699939

Abstract Article PDF–744K

Select item 962912112.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 956995513.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 948193314.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 943756315.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 933831316.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 929024117.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 928740218.

TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis

Dong Suk Yoon, Kyoung-Mi Lee, Yoorim Choi, Eun Ae Ko, Na-Hyun Lee, Sehee Cho, Kwang Hwan Park, Jung-Hwan Lee, Hae-Won Kim, Jin Woo Lee

Cell Death Differ. 2022 Jul; 29(7): 1364–1378. Published online 2022 Jan 16. doi: 10.1038/s41418-021-00925-6

Correction in:: Cell Death Differ. 2022 May; 29(5): 1077.

PMCID:: PMC9287402

Abstract Article PDF–5.7M

Select item 927039819.

TRIM24 is an insulin-responsive regulator of P-bodies

Wen Wei, Qiaoli Chen, Minjun Liu, Yang Sheng, Qian OuYang, Weikuan Feng, Xinyu Yang, Longfei Ding, Shu Su, Jingzi Zhang, Lei Fang, Antonio Vidal-Puig, Hong-Yu Wang, Shuai Chen

Nat Commun. 2022; 13: 3972. Published online 2022 Jul 8. doi: 10.1038/s41467-022-31735-0

PMCID:: PMC9270398

Abstract Article PDF–5.2M

Select item 926262020.

PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing

Swetha Rajasekaran, Eshan Khan, Samuel R Ching, Misbah Khan, Jalal K Siddiqui, Daniela F Gradia, Chenyu Lin, Stephanie J Bouley, Dayna L Mercadante, Amity L Manning, André P Gerber, James A Walker, Wayne O Miles

Nucleic Acids Res. 2022 Jul 8; 50(12): 7048–7066. Published online 2022 Jun 23. doi: 10.1093/nar/gkac499

PMCID:: PMC9262620

Abstract Article PDF–2.8M

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GEO DataSets
Adult acute myeloid leukemia: bone marrow and peripheral blood expression profil...
Adult acute myeloid leukemia: bone marrow and peripheral blood expression profiles (SHCO)
Accession: GDS841

GEO DataSets
clusterin-associated protein 1 isoform 5 [Mus musculus]
clusterin-associated protein 1 isoform 5 [Mus musculus]
gi|2468055736|ref|NP_001405950.1|

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