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Select item 111136111.

E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex

Qiang Zhang, Yanfeng Li, Lei Zhang, Nan Yang, Jiao Meng, Pingping Zuo, Yong Zhang, Jie Chen, Li Wang, Xiang Gao, Dahai Zhu

Cell Mol Life Sci. 2013 Jan; 70(1): 153–165. Published online 2012 Aug 14. doi: 10.1007/s00018-012-1103-5

PMCID:: PMC11113611

Abstract Article PDF–888K

Select item 91197362.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 87953763.

Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteins

Kei Miyakawa, Mayuko Nishi, Michinaga Ogawa, Satoko Matsunaga, Masaya Sugiyama, Hironori Nishitsuji, Hirokazu Kimura, Makoto Ohnishi, Koichi Watashi, Kunitada Shimotohno, Takaji Wakita, Akihide Ryo

Nat Commun. 2022; 13: 531. Published online 2022 Jan 27. doi: 10.1038/s41467-022-28171-5

PMCID:: PMC8795376

Abstract Article PDF–1.9M

Select item 87489584.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 86204295.

RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association

Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Kim Ghilarducci, Saïd Kourrich, Laurent Cappadocia, Marc P. Lussier

Cells. 2021 Nov; 10(11): 3063. Published online 2021 Nov 6. doi: 10.3390/cells10113063

PMCID:: PMC8620429

Abstract Article PDF–7.2M

Select item 85213176.

Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation

Jialiang Shao, Tiezhu Shi, Hua Yu, Yufeng Ding, Liping Li, Xiang Wang, Xiongjun Wang

EMBO J. 2021 Oct 18; 40(20): e107480. Published online 2021 Jul 16. doi: 10.15252/embj.2020107480

Correction in:: EMBO J. 2022 Jan 17; 41(2): e110306.

PMCID:: PMC8521317

Abstract Article PDF–3.6M

Select item 84067237.

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2

Yongzhen Mo, Yumin Wang, Shuai Zhang, Fang Xiong, Qijia Yan, Xianjie Jiang, Xiangying Deng, Yian Wang, Chunmei Fan, Le Tang, Shanshan Zhang, Zhaojian Gong, Fuyan Wang, Qianjin Liao, Can Guo, Yong Li, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong

Mol Cancer. 2021; 20: 112. Published online 2021 Aug 31. doi: 10.1186/s12943-021-01409-4

PMCID:: PMC8406723

Abstract Article PDF–20M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76423279.

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner

Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0

PMCID:: PMC7642327

Abstract Article PDF–12M

Select item 755790210.

The Regulation of circRNA RNF13/miRNA-1224-5p Axis Promotes the Malignant Evolution in Acute Myeloid Leukemia

Rong Zhang, Yingchun Li, Hongtao Wang, Ke Zhu, Guojun Zhang

Biomed Res Int. 2020; 2020: 5654380. Published online 2020 Oct 6. doi: 10.1155/2020/5654380

PMCID:: PMC7557902

Abstract Article PDF–1.8M

Select item 632341611.

Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive

Simon Edvardson, Claudia M. Nicolae, Grace J. Noh, Jennifer E. Burton, Giuseppe Punzi, Avraham Shaag, Jessica Bischetsrieder, Anna De Grassi, Ciro Leonardo Pierri, Orly Elpeleg, George-Lucian Moldovan

Am J Hum Genet. 2019 Jan 3; 104(1): 179–185. Published online 2018 Dec 27. doi: 10.1016/j.ajhg.2018.11.018

PMCID:: PMC6323416

Abstract Article PDF–1.2M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 461721113.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 428236914.

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines

Nikolaos Charlaftis, Tesha Suddason, Xuefeng Wu, Saba Anwar, Michael Karin, Ewen Gallagher

EMBO J. 2014 Nov 3; 33(21): 2581–2596. Published online 2014 Sep 26. doi: 10.15252/embj.201488351

PMCID:: PMC4282369

Abstract Article PDF–3.0M

Select item 360569015.

RNF13, a RING Finger Protein, Mediates Endoplasmic Reticulum Stress-induced Apoptosis through the Inositol-requiring Enzyme (IRE1α)/c-Jun NH₂-terminal Kinase Pathway

Muhammad Arshad, Zhongde Ye, Xiaofeng Gu, Chung Kai Wong, Yang Liu, De Li, Linkang Zhou, Yi Zhang, Wan Ping Bay, Victor C. Yu, Peng Li

J Biol Chem. 2013 Mar 22; 288(12): 8726–8736. Published online 2013 Feb 1. doi: 10.1074/jbc.M112.368829

PMCID:: PMC3605690

Abstract Article PDF–2.1M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 273665217.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Abstract Article PDF–5.6M

Select item 264419218.

The Role of Metallothionein in the Pathogenesis of Acute Lung Injury

Scott C. Wesselkamper, Susan A. McDowell, Mario Medvedovic, Timothy P. Dalton, Hitesh S. Deshmukh, Maureen A. Sartor, Lisa M. Case, Lisa N. Henning, Michael T. Borchers, Craig R. Tomlinson, Daniel R. Prows, George D. Leikauf

Am J Respir Cell Mol Biol. 2006 Jan; 34(1): 73–82. Published online 2005 Sep 15. doi: 10.1165/rcmb.2005-0248OC

PMCID:: PMC2644192

Abstract Article PDF–174K

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406