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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100058982.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 95730923.

Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins

Fengwen Zhang, Trinity M. Zang, Eva M. Stevenson, Xiao Lei, Dennis C. Copertino, Talia M. Mota, Julie Boucau, Wilfredo F. Garcia-Beltran, R. Brad Jones, Paul D. Bieniasz

Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2209042119. Published online 2022 Sep 22. doi: 10.1073/pnas.2209042119

PMCID:: PMC9573092

Abstract Article PDF–2.6M

Select item 92413854.

Spotlight on TAP and its vital role in antigen presentation and cross-presentation

Ian Mantel, Barzan A. Sadiq, J. Magarian Blander

Mol Immunol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Mol Immunol. 2022 Feb; 142: 105–119. Published online 2021 Dec 29. doi: 10.1016/j.molimm.2021.12.013

PMCID:: PMC9241385

Abstract Article PDF–762K

Select item 92316235.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91197366.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90405567.

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan

Science. Author manuscript; available in PMC 2022 Apr 26.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066

PMCID:: PMC9040556

Abstract Article PDF–2.2M

Select item 88970228.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 85529079.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 828276410.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808018612.

Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population

Mingwu Zhang, Xiaomeng Wang, Yelei Zhu, Songhua Chen, Bin Chen, Zhengwei Liu

Epidemiol Infect. 2021; 149: e79. Published online 2021 Mar 19. doi: 10.1017/S0950268821000613

PMCID:: PMC8080186

Abstract Article PDF–138K

Select item 732206713.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 694931114.

Analysis of transporter associated with antigen presentation (TAP) genes polymorphisms with HIV-1 infection

Abaineh Munshea Abitew, Ranbir Chander Sobti, Vijay Lakshmi Sharma, Ajay Wanchu

Mol Cell Biochem. 2020; 464(1): 65–71. Published online 2019 Nov 16. doi: 10.1007/s11010-019-03649-x

PMCID:: PMC6949311

Abstract Article PDF–735K

Select item 680760315.

Association between the TAP2 gene codon 665 polymorphism and Graves' Disease

Rong‐Hsing Chen, Tze‐Yuan Wang, Wen‐Chi Chen, Chang‐Hai Tsai, Fuu‐Jen Tsai

J Clin Lab Anal. 2006; 20(3): 93–97. Published online 2006 May 23. doi: 10.1002/jcla.20107

PMCID:: PMC6807603

Abstract Article PDF–125K

Select item 659455116.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 593263117.

Genetic Variants in TAP Are Associated with High-Grade Cervical Neoplasia

Mark H. Einstein, Suzanne Leanza, Lydia G. Chiu, Nicolas F. Schlecht, Gary L. Goldberg, Bettie M. Steinberg, Robert D. Burk

Clin Cancer Res. Author manuscript; available in PMC 2018 May 3.

Published in final edited form as: Clin Cancer Res. 2009 Feb 1; 15(3): 1019–1023. doi: 10.1158/1078-0432.CCR-08-1207

PMCID:: PMC5932631

Abstract Article PDF–324K

Select item 581132118.

A Functional SNP in the 3′-UTR of TAP2 Gene Interacts with MicroRNA Hsa-miR-1270 to Suppress the Gene Expression

Bridgett Knox, Yong Wang, Lora J. Rogers, Jiekun Xuan, Dianke Yu, Huaijin Guan, Jiwei Chen, Tieliu Shi, Baitang Ning, Susan A. Kadlubar

Environ Mol Mutagen. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Environ Mol Mutagen. 2018 Mar; 59(2): 134–143. Published online 2017 Dec 5. doi: 10.1002/em.22159

PMCID:: PMC5811321

Abstract Article PDF–1.2M

Select item 570663019.

Downregulation of TAP1 and TAP2 in early stage breast cancer

Andrea M. Henle, Aziza Nassar, Danell Puglisi-Knutson, Bahaaeldin Youssef, Keith L. Knutson

PLoS One. 2017; 12(11): e0187323. Published online 2017 Nov 1. doi: 10.1371/journal.pone.0187323

PMCID:: PMC5706630

Abstract Article PDF–1.2M

Select item 570387820.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Abstract Article PDF–3.7M

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