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Select item 111617241.

DRD1 suppresses cell proliferation and reduces EGFR activation and PD‐L1 expression in NSCLC

Christopher E. Grant, Amy L. Flis, Leila Toulabi, Adriana Zingone, Emily Rossi, Krist Aploks, Heather Sheppard, Bríd M. Ryan

Mol Oncol. 2024 Jun; 18(6): 1631–1648. Published online 2024 Apr 4. doi: 10.1002/1878-0261.13608

PMCID:: PMC11161724

Abstract Article PDF–3.4M

Select item 110059402.

Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes

Peng Xiao, Wei Yan, Lu Gou, Ya-Ni Zhong, Liangliang Kong, Chao Wu, Xin Wen, Yuan Yuan, Sheng Cao, Changxiu Qu, Xin Yang, Chuan-Cheng Yang, Anjie Xia, Zhenquan Hu, Qianqian Zhang, Yong-Hao He, Dao-Lai Zhang, Chao Zhang, Gui-Hua Hou, Huanxiang Liu, Lizhe Zhu, Ping Fu, Shengyong Yang, Daniel M. Rosenbaum, Jin-Peng Sun, Yang Du, Lei Zhang, Xiao Yu, Zhenhua Shao

Cell. Author manuscript; available in PMC 2024 Apr 10.

Published in final edited form as: Cell. 2021 Feb 18; 184(4): 943–956.e18. Published online 2021 Feb 10. doi: 10.1016/j.cell.2021.01.028

PMCID:: PMC11005940

Abstract Article PDF–1.8M

Select item 109410713.

Dopamine D1-Receptor Organization Contributes to Functional Brain Architecture

Robin Pedersen, Jarkko Johansson, Kristin Nordin, Anna Rieckmann, Anders Wåhlin, Lars Nyberg, Lars Bäckman, Alireza Salami

J Neurosci. 2024 Mar 13; 44(11): e0621232024. Prepublished online 2024 Feb 1. doi: 10.1523/JNEUROSCI.0621-23.2024

PMCID:: PMC10941071

Abstract Article PDF–3.5M

Select item 100674014.

Inhibition of dopamine receptor D1 signaling promotes human bile duct cancer progression via WNT signaling

Akitada Yogo, Toshihiko Masui, Shigeo Takaishi, Kenji Masuo, Ru Chen, Yosuke Kasai, Kazuyuki Nagai, Takayuki Anazawa, Sadanori Watanabe, Satoko Sakamoto, Akira Watanabe, Ryosaku Inagaki, Masahiro M. Nakagawa, Seishi Ogawa, Hiroshi Seno, Shinji Uemoto, Etsuro Hatano

Cancer Sci. 2023 Apr; 114(4): 1324–1336. Published online 2022 Dec 14. doi: 10.1111/cas.15676

PMCID:: PMC10067401

Abstract Article PDF–15M

Select item 100286345.

Unravelling neurotransmitters impairment in primary progressive aphasias

Enrico Premi, Juergen Dukart, Irene Mattioli, Ilenia Libri, Marta Pengo, Yasmine Gadola, Maria Cotelli, Rosa Manenti, Giuliano Binetti, Stefano Gazzina, Antonella Alberici, Mauro Magoni, Giacomo Koch, Roberto Gasparotti, Alessandro Padovani, Barbara Borroni

Hum Brain Mapp. 2023 Apr 15; 44(6): 2245–2253. Published online 2023 Jan 17. doi: 10.1002/hbm.26206

PMCID:: PMC10028634

Abstract Article PDF–2.9M

Select item 89938406.

Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis

Karolin Wieber, Leonie Fleige, Styliani Tsiami, Jörg Reinders, Jürgen Braun, Xenofon Baraliakos, Silvia Capellino

Sci Rep. 2022; 12: 5985. Published online 2022 Apr 8. doi: 10.1038/s41598-022-09891-6

PMCID:: PMC8993840

Abstract Article PDF–5.3M

Select item 87779307.

HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk

Qiujin Yan, Xiulin Wu, Ping Zhou, Yan Zhou, Xuhang Li, Zhongchun Liu, Huawei Tan, Wei Yao, Yaru Xia, Fan Zhu

Viruses. 2022 Jan; 14(1): 145. Published online 2022 Jan 14. doi: 10.3390/v14010145

PMCID:: PMC8777930

Abstract Article PDF–31M

Select item 84395938.

Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward

Rui Zhang, Peter Manza, Dardo Tomasi, Sung Won Kim, Ehsan Shokri-Kojori, Sukru B. Demiral, Danielle S. Kroll, Dana E. Feldman, Katherine L. McPherson, Catherine L. Biesecker, Gene-Jack Wang, Nora D. Volkow

J Clin Invest. 2021 Sep 15; 131(18): e149722. Published online 2021 Sep 15. doi: 10.1172/JCI149722

PMCID:: PMC8439593

Abstract Article PDF–2.3M

Select item 82156869.

Structural insights into the human D1 and D2 dopamine receptor signaling complexes

Youwen Zhuang, Peiyu Xu, Chunyou Mao, Lei Wang, Brian Krumm, X. Edward Zhou, Sijie Huang, Heng Liu, Xi Cheng, Xi-Ping Huang, Dan-Dan Shen, Tinghai Xu, Yong-Feng Liu, Yue Wang, Jia Guo, Yi Jiang, Hualiang Jiang, Karsten Melcher, Bryan L. Roth, Yan Zhang, Cheng Zhang, H. Eric Xu

Cell. Author manuscript; available in PMC 2021 Jun 21.

Published in final edited form as: Cell. 2021 Feb 18; 184(4): 931–942.e18. Published online 2021 Feb 10. doi: 10.1016/j.cell.2021.01.027

PMCID:: PMC8215686

Abstract Article PDF–3.1M

Select item 817545810.

Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist

Bingfa Sun, Dan Feng, Matthew Ling-Hon Chu, Inbar Fish, Silvia Lovera, Zara A. Sands, Sebastian Kelm, Anne Valade, Martyn Wood, Tom Ceska, Tong Sun Kobilka, Florence Lebon, Brian K. Kobilka

Nat Commun. 2021; 12: 3305. Published online 2021 Jun 3. doi: 10.1038/s41467-021-23519-9

PMCID:: PMC8175458

Abstract Article PDF–1.5M

Select item 808909911.

Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor

Youwen Zhuang, Brian Krumm, Huibing Zhang, X. Edward Zhou, Yue Wang, Xi-Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hualiang Jiang, Cheng Zhang, Wei Yi, Bryan L. Roth, Yan Zhang, H. Eric Xu

Cell Res. 2021 May; 31(5): 593–596. Published online 2021 Mar 9. doi: 10.1038/s41422-021-00482-0

PMCID:: PMC8089099

Article PDF–1.4M

Select item 780647512.

DRD1 downregulation contributes to mechanical stretch-induced lung endothelial barrier dysfunction

Yan Wang, Yu-Jian Liu, Dun-Feng Xu, Hui Zhang, Chu-Fan Xu, Yan-Fei Mao, Zhou Lv, Xiao-Yan Zhu, Lai Jiang

Theranostics. 2021; 11(6): 2505–2521. Published online 2021 Jan 1. doi: 10.7150/thno.46192

PMCID:: PMC7806475

Abstract Article PDF–3.7M

Select item 776172913.

Smoking Genes: A Case–Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort

Abu Bakar Ruzilawati, Md Asiful Islam, Siti Khariem Sophia Muhamed, Imran Ahmad

Biomolecules. 2020 Dec; 10(12): 1633. Published online 2020 Dec 3. doi: 10.3390/biom10121633

PMCID:: PMC7761729

Abstract Article PDF–287K

Select item 747221414.

Corticostriatal White Matter Integrity and Dopamine D1 Receptor Availability Predict Age Differences in Prefrontal Value Signaling during Reward Learning

Lieke de Boer, Benjamín Garzón, Jan Axelsson, Katrine Riklund, Lars Nyberg, Lars Bäckman, Marc Guitart-Masip

Cereb Cortex. 2020 Oct; 30(10): 5270–5280. Published online 2020 Jun 2. doi: 10.1093/cercor/bhaa104

PMCID:: PMC7472214

Abstract Article PDF–586K

Select item 745930415.

Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure

Toshihiro Yamaguchi, Tomokazu S. Sumida, Seitaro Nomura, Masahiro Satoh, Tomoaki Higo, Masamichi Ito, Toshiyuki Ko, Kanna Fujita, Mary E. Sweet, Atsushi Sanbe, Kenji Yoshimi, Ichiro Manabe, Toshikuni Sasaoka, Matthew R. G. Taylor, Haruhiro Toko, Eiki Takimoto, Atsuhiko T. Naito, Issei Komuro

Nat Commun. 2020; 11: 4364. Published online 2020 Aug 31. doi: 10.1038/s41467-020-18128-x