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Select item 111584771.

Expression of Autotaxin and Acylglycerol kinase in prostate cancer: Association with cancer development and progression

Mohammed Ahmed Abdel Muneem Nouh, Xiu‐Xian Wu, Homare Okazoe, Hiroyuki Tsunemori, Reiji Haba, Abdel Muneem Mohammed Abou‐Zeid, Mohammed Diaa Saleem, Masashi Inui, Mikio Sugimoto, Junken Aoki, Yoshiyuki Kakehi

Cancer Sci. 2009 Sep; 100(9): 1631–1638. Published online 2009 May 31. doi: 10.1111/j.1349-7006.2009.01234.x

PMCID:: PMC11158477

Abstract Article PDF–13M

Select item 111155232.

Autotaxin

Jean A. Boutin, Gilles Ferry

Cell Mol Life Sci. 2009 Sep; 66(18): 3009–3021. Published online 2009 Jun 9. doi: 10.1007/s00018-009-0056-9

PMCID:: PMC11115523

Abstract Article PDF–450K

Select item 107280223.

Dual role of autotaxin as novel biomarker and therapeutic target in pancreatic neuroendocrine neoplasms

Tadashi Toyohara, Michihiro Yoshida, Katsuyuki Miyabe, Kazuki Hayashi, Itaru Naitoh, Hiromu Kondo, Yasuki Hori, Akihisa Kato, Kenta Kachi, Go Asano, Hidenori Sahashi, Akihisa Adachi, Kayoko Kuno, Yusuke Kito, Yoichi Matsuo, Hiromi Kataoka

Cancer Sci. 2023 Dec; 114(12): 4571–4582. Published online 2023 Sep 28. doi: 10.1111/cas.15980

PMCID:: PMC10728022

Abstract Article PDF–2.5M

Select item 103640774.

E2F7 drives Autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not human carcinomas

Kuan-Hung Lin, Sue Chin Lee, Mélanie A. Dacheux, Derek D. Norman, Andrea Balogh, Mitul Bavaria, Hsinyu Lee, Gabor Tigyi

FASEB J. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: FASEB J. 2023 Jul; 37(7): e23058. doi: 10.1096/fj.202300838R

PMCID:: PMC10364077

Abstract Article PDF–2.6M

Select item 101795335.

The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer

Christiana Magkrioti, Eleanna Kaffe, Vassilis Aidinis

Int J Mol Sci. 2023 May; 24(9): 8325. Published online 2023 May 5. doi: 10.3390/ijms24098325

PMCID:: PMC10179533

Article PDF–272K

Select item 101384856.

Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF-2α-Dependent Manner

Mengxia Qu, Yang Long, Yuqin Wang, Nan Yin, Xiaotian Zhang, Junjie Zhang

Int J Mol Sci. 2023 Apr; 24(8): 7031. Published online 2023 Apr 11. doi: 10.3390/ijms24087031

PMCID:: PMC10138485

Abstract Article PDF–3.5M

Select item 94961807.

Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor

Mengxuan Liu, Megumi Honjo, Reiko Yamagishi, Nozomi Igarashi, Natsuko Nakamura, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Makoto Aihara

Biomolecules. 2022 Sep; 12(9): 1231. Published online 2022 Sep 3. doi: 10.3390/biom12091231

PMCID:: PMC9496180

Abstract Article PDF–3.2M

Select item 94092728.

Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells

Yang Liu, Reiko Yamagishi, Megumi Honjo, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Makoto Aihara

Int J Mol Sci. 2022 Aug; 23(16): 9181. Published online 2022 Aug 16. doi: 10.3390/ijms23169181

PMCID:: PMC9409272

Abstract Article PDF–4.7M

Select item 93485769.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 899899210.

ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker

Maria Panagopoulou, Andrianna Drosouni, Dionysiοs Fanidis, Makrina Karaglani, Ioanna Balgkouranidou, Nikolaos Xenidis, Vassilis Aidinis, Ekaterini Chatzaki

Int J Mol Sci. 2022 Apr; 23(7): 3717. Published online 2022 Mar 28. doi: 10.3390/ijms23073717

PMCID:: PMC8998992

Abstract Article PDF–2.2M

Select item 876135911.

Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8⁺ T cells

Elisa Matas-Rico, Elselien Frijlink, Irene van der Haar Àvila, Apostolos Menegakis, Maaike van Zon, Andrew J. Morris, Jan Koster, Fernando Salgado-Polo, Sander de Kivit, Telma Lança, Antonio Mazzocca, Zoë Johnson, John Haanen, Ton N. Schumacher, Anastassis Perrakis, Inge Verbrugge, Joost H. van den Berg, Jannie Borst, Wouter H. Moolenaar

Cell Rep. Author manuscript; available in PMC 2022 Jan 16.

Published in final edited form as: Cell Rep. 2021 Nov 16; 37(7): 110013. doi: 10.1016/j.celrep.2021.110013

PMCID:: PMC8761359

Abstract Article PDF–2.7M

Select item 858501312.

ENPP2 Methylation in Health and Cancer

Maria Panagopoulou, Dionysios Fanidis, Vassilis Aidinis, Ekaterini Chatzaki

Int J Mol Sci. 2021 Nov; 22(21): 11958. Published online 2021 Nov 4. doi: 10.3390/ijms222111958

PMCID:: PMC8585013

Abstract Article PDF–2.4M

Select item 855105813.

LPA and Autotaxin: Potential drug targets in asthma?

Steve N. Georas

Cell Biochem Biophys. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Cell Biochem Biophys. 2021 Sep; 79(3): 445–448. Published online 2021 Jul 31. doi: 10.1007/s12013-021-01023-7

PMCID:: PMC8551058

Abstract Article PDF–46K

Select item 846927914.

Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells

Ioanna Nikitopoulou, Dionysios Fanidis, Konstantinos Ntatsoulis, Panagiotis Moulos, George Mpekoulis, Maria Evangelidou, Alice G. Vassiliou, Vasiliki Dimakopoulou, Edison Jahaj, Stamatios Tsipilis, Stylianos E. Orfanos, Ioanna Dimopoulou, Emmanouil Angelakis, Karolina Akinosoglou, Niki Vassilaki, Argyrios Tzouvelekis, Anastasia Kotanidou, Vassilis Aidinis

Int J Mol Sci. 2021 Sep; 22(18): 10006. Published online 2021 Sep 16. doi: 10.3390/ijms221810006

PMCID:: PMC8469279

Abstract Article PDF–1.6M

Select item 843104315.

Autotaxin-LPA-LPP3 Axis in Energy Metabolism and Metabolic Disease

Anu Jose, Petra C. Kienesberger

Int J Mol Sci. 2021 Sep; 22(17): 9575. Published online 2021 Sep 3. doi: 10.3390/ijms22179575

PMCID:: PMC8431043

Abstract Article PDF–826K

Select item 821247616.

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Nozomi Igarashi, Megumi Honjo, Reiko Yamagishi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Toshikatsu Kaburaki, Makoto Aihara

J Biomed Sci. 2021; 28: 47. Published online 2021 Jun 17. doi: 10.1186/s12929-021-00745-3

PMCID:: PMC8212476

Abstract Article PDF–3.8M

Select item 787705217.

Evaluation of serum ATX and LPA as potential diagnostic biomarkers in patients with pancreatic cancer

Jiang Chen, Hongyu Li, Wenda Xu, Xiaozhong Guo

BMC Gastroenterol. 2021; 21: 58. Published online 2021 Feb 10. doi: 10.1186/s12876-021-01635-6

PMCID:: PMC7877052

Abstract Article PDF–1.0M

Select item 774411218.

Autotaxin Inhibition Reduces Cardiac Inflammation and Mitigates Adverse Cardiac Remodeling After Myocardial Infarction

Himi Tripathi, Ahmed Al-Darraji, Mohamed Abo-Aly, Hsuan Peng, Elica Shokri, Lakshman Chelvarajan, Renee Donahue, Bryana M. Levitan, Erhe Gao, Gabriela Hernandez, Andrew J. Morris, Susan S. Smyth, Ahmed Abdel-Latif

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Dec; 149: 95–114. Published online 2020 Oct 2. doi: 10.1016/j.yjmcc.2020.09.011

PMCID:: PMC7744112

Abstract Article PDF–3.2M

Select item 771826919.

Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis

Pengxiu Cao, Natalie M. Walker, Russell R. Braeuer, Serina Mazzoni-Putman, Yoshiro Aoki, Keizo Misumi, David S. Wheeler, Ragini Vittal, Vibha N. Lama

Sci Rep. 2020; 10: 21231. Published online 2020 Dec 4. doi: 10.1038/s41598-020-77601-1

PMCID:: PMC7718269

Abstract Article PDF–1.7M

Select item 758270520.

Structure-Based Discovery of Novel Chemical Classes of Autotaxin Inhibitors

Christiana Magkrioti, Eleanna Kaffe, Elli-Anna Stylianaki, Camelia Sidahmet, Georgia Melagraki, Antreas Afantitis, Alexios N. Matralis, Vassilis Aidinis

Int J Mol Sci. 2020 Oct; 21(19): 7002. Published online 2020 Sep 23. doi: 10.3390/ijms21197002

PMCID:: PMC7582705

Abstract Article PDF–3.2M

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