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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 101786952.

The Role of the Estrogen-Related Receptor Alpha (ERRa) in Hypoxia and Its Implications for Cancer Metabolism

Leslie Chaltel-Lima, Fabiola Domínguez, Lenin Domínguez-Ramírez, Paulina Cortes-Hernandez

Int J Mol Sci. 2023 May; 24(9): 7983. Published online 2023 Apr 28. doi: 10.3390/ijms24097983

PMCID:: PMC10178695

Abstract Article PDF–2.9M

Select item 100022333.

Multifaceted Transcriptional Network of Estrogen-Related Receptor Alpha in Health and Disease

Catherine Cerutti, Jing-Ru Shi, Jean-Marc Vanacker

Int J Mol Sci. 2023 Mar; 24(5): 4265. Published online 2023 Feb 21. doi: 10.3390/ijms24054265

PMCID:: PMC10002233

Abstract Article PDF–1.8M

Select item 99644224.

ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis

Shuting Tang, Jincheng Ma, Pingping Su, Huifang Lei, Yao Tong, Liangzhi Cai, Shuxia Xu, Xiaodan Mao, Pengming Sun

Int J Mol Sci. 2023 Feb; 24(4): 4010. Published online 2023 Feb 16. doi: 10.3390/ijms24044010

PMCID:: PMC9964422

Abstract Article PDF–4.5M

Select item 96941315.

Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC

Katarzyna Nowińska, Karolina Jabłońska, Urszula Ciesielska, Aleksandra Piotrowska, Katarzyna Haczkiewicz-Leśniak, Konrad Pawełczyk, Marzenna Podhorska-Okołów, Piotr Dzięgiel

Int J Mol Sci. 2022 Nov; 23(22): 14204. Published online 2022 Nov 17. doi: 10.3390/ijms232214204

PMCID:: PMC9694131

Abstract Article PDF–7.6M

Select item 95699556.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 93447067.

IGF2BP1-regulated expression of ERRα is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells

Qing He, Peng Hao, Gang He, Hantao Mai, Wenzhou Liu, Weiqiong Zhang, Kelin Zhang, Guifang Zhong, Ruilian Guo, Changzhi Yu, Yang Li, Chipiu Wong, Qian Chen, Yantao Chen

J Transl Med. 2022; 20: 348. Published online 2022 Aug 2. doi: 10.1186/s12967-022-03549-7

PMCID:: PMC9344706

Abstract Article PDF–4.5M

Select item 92902418.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 92792859.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 910523510.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 890720011.

Computational identification of new potential transcriptional partners of ERRα in breast cancer cells: specific partners for specific targets

Catherine Cerutti, Ling Zhang, Violaine Tribollet, Jing-Ru Shi, Riwan Brillet, Benjamin Gillet, Sandrine Hughes, Christelle Forcet, Tie-Liu Shi, Jean-Marc Vanacker

Sci Rep. 2022; 12: 3826. Published online 2022 Mar 9. doi: 10.1038/s41598-022-07744-w

PMCID:: PMC8907200

Abstract Article PDF–2.4M

Select item 880641112.

Declined expressions of vast mitochondria-related genes represented by CYCS and transcription factor ESRRA in skeletal muscle aging

Jingbao Kan, Yifang Hu, Yaoqi Ge, WenSong Zhang, Shan Lu, Cuiping Zhao, Rihua Zhang, Yun Liu

Bioengineered. 2021; 12(1): 3485–3502. Published online 2021 Jul 6. doi: 10.1080/21655979.2021.1948951

PMCID:: PMC8806411

Abstract Article PDF–8.3M

Select item 875396813.

Roles of ERRα and TGF-β signaling in stemness enhancement induced by 1 µM bisphenol A exposure via human neural stem cells

Panpan Dong, Ganghui Ye, Xinzhuo Tu, Ying Luo, Weitong Cui, Yuxin Ma, Lei Wei, Xuewen Tian, Qinglu Wang

Exp Ther Med. 2022 Feb; 23(2): 164. Published online 2021 Dec 22. doi: 10.3892/etm.2021.11087

PMCID:: PMC8753968

Abstract Article PDF–3.7M

Select item 838261614.

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes

Rasmus J. O. Sjögren, David Rizo-Roca, Alexander V. Chibalin, Elin Chorell, Regula Furrer, Shintaro Katayama, Jun Harada, Håkan K. R. Karlsson, Christoph Handschin, Thomas Moritz, Anna Krook, Erik Näslund, Juleen R. Zierath

Diabetologia. 2021; 64(9): 2077–2091. Published online 2021 Jun 16. doi: 10.1007/s00125-021-05481-9

PMCID:: PMC8382616

Abstract Article PDF–4.1M

Select item 825846215.

PI3K/AKT phosphorylation activates ERRα by upregulating PGC-1α and PGC-1β in gallbladder cancer

Lei Wang, Mengmeng Yang, Huihan Jin

Mol Med Rep. 2021 Aug; 24(2): 613. Published online 2021 Jun 28. doi: 10.3892/mmr.2021.12252

PMCID:: PMC8258462

Abstract Article PDF–2.1M

Select item 821690916.

Triple-negative breast lobular carcinoma: a luminal androgen receptor carcinoma with specific ESRRA mutations

Anthony Bergeron, Gaëtan MacGrogan, Aurélie Bertaut, Sylvain Ladoire, Patrick Arveux, Isabelle Desmoulins, Hervé Bonnefoi, Catherine Loustalot, Sophie Auriol, Françoise Beltjens, Emilie Degrolard-Courcet, Céline Charon-Barra, Corentin Richard, Romain Boidot, Laurent Arnould

Mod Pathol. 2021; 34(7): 1282–1296. Published online 2021 Mar 22. doi: 10.1038/s41379-021-00742-9

PMCID:: PMC8216909

Abstract Article PDF–2.7M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800904818.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 795030019.

Down-regulation of estrogen-related receptor alpha (ERRα) inhibits gastric cancer cell migration and invasion in vitro and in vivo

Yuejiao Zhong, Kang He, Lin Shi, Lingxiang Chen, Bin Zhou, Rong Ma, Hui Yu, Jia Zhang, You Shuai, Yan Fei, Jianwei Lu

Aging (Albany NY) 2021 Feb 28; 13(4): 5845–5857. Published online 2021 Feb 11. doi: 10.18632/aging.202508

PMCID:: PMC7950300

Abstract Article PDF–1.5M

Select item 787135020.

Comprehensive Analysis of ESRRA in Endometrial Cancer

Shufang Wang, Xinlong Huo

Technol Cancer Res Treat. 2021; 20: 1533033821992083. Published online 2021 Feb 2. doi: 10.1177/1533033821992083

PMCID:: PMC7871350

Abstract Article PDF–1.8M

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