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Items: 1 to 20 of 56

1.
circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma
Xiang Li, Chenxing Wang, Hang Zhang, Yangjie Li, Deqiang Hou, Dingshan Liu, Rongyao Xu, Jie Cheng, Laikui Liu, Yu Fu, Jinhai Ye, Hongbing Jiang
Cancer Res. 2023 May 2; 83(9): 1459–1475. Published online 2023 Feb 22. doi: 10.1158/0008-5472.CAN-22-2585
PMCID:
PMC10152237
AbstractArticlePDF–22M
2.
Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer
Wei-Yu Chen, Phan Vu Thuy Dung, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Zi-Qing Chen, Michael Hsiao, Jiaoti Huang, Yu-Ching Wen, Yen-Nien Liu
Redox Biol. 2023 Jun; 62: 102686. Published online 2023 Mar 21. doi: 10.1016/j.redox.2023.102686
PMCID:
PMC10060381
AbstractArticlePDF–18M
3.
Blocking MG53S255 Phosphorylation Protects Diabetic Heart From Ischemic Injury
Fengxiang Lv, Yingfan Wang, Dan Shan, Sile Guo, Gengjia Chen, Li Jin, Wen Zheng, Han Feng, Xiaohu Zeng, Shuo Zhang, Yan Zhang, Xinli Hu, Rui-Ping Xiao
Circ Res. 2022 Dec 2; 131(12): 962–976. Published online 2022 Nov 7. doi: 10.1161/CIRCRESAHA.122.321055
PMCID:
PMC9770150
AbstractArticlePDF–7.3M
4.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB
Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan
EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698
PMCID:
PMC9433938
AbstractArticlePDF–9.3M
5.
Haematological profile of malaria patients with G6PD and PKLR variants (erythrocytic enzymopathies): a cross-sectional study in Thailand
Punchalee Mungkalasut, Patcharakorn Kiatamornrak, Watcharapong Jugnam-Ang, Srivicha Krudsood, Poonlarp Cheepsunthorn, Chalisa Louicharoen Cheepsunthorn
Malar J. 2022; 21: 250. Published online 2022 Aug 30. doi: 10.1186/s12936-022-04267-7
PMCID:
PMC9426002
AbstractArticlePDF–1.5M
6.
Genetic variants of PKLR are associated with acute pain in sickle cell disease
Xunde Wang, Kate Gardner, Mickias B. Tegegn, Clifton L. Dalgard, Camille Alba, Stephan Menzel, Hamel Patel, Mehdi Pirooznia, Yi-Ping Fu, Fayaz T. Seifuddin, Swee Lay Thein
Blood Adv. 2022 Jun 14; 6(11): 3535–3540. Published online 2022 Jun 13. doi: 10.1182/bloodadvances.2021006668
PMCID:
PMC9198922
AbstractArticlePDF–859K
7.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
8.
Identification of biochemically neutral positions in liver pyruvate kinase
Tyler A. Martin, Tiffany Wu, Qingling Tang, Larissa L. Dougherty, Daniel J. Parente, Liskin Swint-Kruse, Aron W. Fenton
Proteins. Author manuscript; available in PMC 2022 Apr 8.
Published in final edited form as: Proteins. 2020 Oct; 88(10): 1340–1350. Published online 2020 Jun 27. doi: 10.1002/prot.25953
PMCID:
PMC8990530
AbstractArticlePDF–1.0M
9.
Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency
Yu-Ching Wen, Wei-Yu Chen, Van Thi Ngoc Tram, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Wassim Abou-Kheir, Jiaoti Huang, Michael Hsiao, Yen-Nien Liu
Cell Death Dis. 2022 Mar; 13(3): 252. Published online 2022 Mar 19. doi: 10.1038/s41419-022-04694-z
PMCID:
PMC8934352
AbstractArticlePDF–6.4M
10.
A novel homozygous missense variant p.D339N in the PKLR gene correlates with pyruvate kinase deficiency in a Pakistani family: a case report
Atta Ur Rehman, Abdur Rashid, Zubair Hussain, Khadim Shah
J Med Case Rep. 2022; 16: 66. Published online 2022 Feb 16. doi: 10.1186/s13256-022-03292-z
PMCID:
PMC8848962
AbstractArticlePDF–1.3M
11.
Putative pathogen-selected polymorphisms in the PKLR gene are associated with mycobacterial susceptibility in Brazilian and African populations
Ohanna Cavalcanti de Lima Bezerra, Lucia Elena Alvarado-Arnez, Nédio Mabunda, Graça Salomé, Amina de Sousa, Fernanda de Souza Gomes Kehdy, Carolinne Sales-Marques, Fernanda Saloum de Neves Manta, Rafaela Mota Andrade, Laís Pereira Ferreira, Thyago Leal-Calvo, Cynthia Chester Cardoso, Kelly Nunes, Mateus H. Gouveia, Sam M. Mbulaiteve, Edward D. Yeboah, Ann Hsing, Ana Carla Pereira Latini, André Luiz Leturiondo, Fabíola da Costa Rodrigues, Ariani Batista Noronha, Cynthia de Oliveira Ferreira, Carolina Talhari, Jamile Leão Rêgo, Léa Cristina de Carvalho Castellucci, Eduardo Tarazona-Santos, Elizeu Fagundes de Carvalho, Diogo Meyer, Roberta Olmo Pinheiro, Ilesh V. Jani, Antonio Guilherme Pacheco, Milton Ozório Moraes
PLoS Negl Trop Dis. 2021 Aug; 15(8): e0009434. Published online 2021 Aug 27. doi: 10.1371/journal.pntd.0009434
PMCID:
PMC8396769
AbstractArticlePDF–1.7M
12.
Rheostat functional outcomes occur when substitutions are introduced at nonconserved positions that diverge with speciation
Liskin Swint‐Kruse, Tyler A. Martin, Braelyn M. Page, Tiffany Wu, Paige M. Gerhart, Larissa L. Dougherty, Qingling Tang, Daniel J. Parente, Brian R. Mosier, Leonidas E. Bantis, Aron W. Fenton
Protein Sci. 2021 Sep; 30(9): 1833–1853. Published online 2021 Jun 11. doi: 10.1002/pro.4136
PMCID:
PMC8376419
AbstractArticlePDF–4.8M
13.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
14.
Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation
Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee
Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572
PMCID:
PMC8307194
AbstractArticlePDF–2.8M
15.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
16.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner
Karthickeyan Chella Krishnan, Raquel R. Floyd, Simon Sabir, Dulshan W. Jayasekera, Paola V. Leon-Mimila, Anthony E. Jones, Angel A. Cortez, Varun Shravah, Miklós Péterfy, Linsey Stiles, Samuel Canizales-Quinteros, Ajit S. Divakaruni, Adriana Huertas-Vazquez, Aldons J. Lusis
Cell Mol Gastroenterol Hepatol. 2021; 11(2): 389–406. Published online 2020 Sep 14. doi: 10.1016/j.jcmgh.2020.09.004
PMCID:
PMC7788245
AbstractArticlePDF–4.6M
17.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
18.
Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex
Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle
Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834
PMCID:
PMC7226812
AbstractArticlePDF–2.3M
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
SARS-CoV nucleocapsid protein interacts with cellular pyruvate kinase protein and inhibits its activity
Wei-Yen Wei, Hui-Chun Li, Chiung-Yao Chen, Chee-Hing Yang, Shen-Kao Lee, Chia-Wen Wang, Hsin-Chieh Ma, Yue-Li Juang, Shih-Yen Lo
Arch Virol. 2012; 157(4): 635–645. Published online 2012 Jan 6. doi: 10.1007/s00705-011-1221-7
PMCID:
PMC7087308
AbstractArticlePDF–549K

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