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Select item 107177041.

Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium–coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12)

Sunena Srivastava, Kiyoshi Nakagawa, Xin He, Toru Kimura, Toshiyuki Fukutomi, Seiji Miyauchi, Hiroyuki Sakurai, Naohiko Anzai

J Physiol Sci. 2019 Mar; 69(2): 399–408. Published online 2019 Jan 2. doi: 10.1007/s12576-018-00658-1

PMCID:: PMC10717704

Abstract Article PDF–1.0M

Select item 107173322.

Sodium-coupled monocarboxylate transporter 1 interacts with the RING finger- and PDZ domain-containing protein PDZRN3

Yusuke Otsuka, Tomomi Furihata, Kiyoshi Nakagawa, Yuta Ohno, Yoshie Reien, Motoshi Ouchi, Hidefumi Wakashin, Shuichi Tsuruoka, Naohiko Anzai

J Physiol Sci. 2019 Jul; 69(4): 635–642. Published online 2019 May 16. doi: 10.1007/s12576-019-00681-w

PMCID:: PMC10717332

Abstract Article PDF–840K

Select item 106759313.

Role of hypermethylated SLC5A8 in follicular thyroid cancer diagnosis and prognosis prediction

Yan Yang, Chenjin Liao, Qian Yang, Yuxia Li, Yunxiang Tang, Bin Xu

World J Surg Oncol. 2023; 21: 367. Published online 2023 Nov 25. doi: 10.1186/s12957-023-03240-1

PMCID:: PMC10675931

Abstract Article PDF–1.5M

Select item 94824484.

Structure and mechanism of the SGLT family of glucose transporters

Lei Han, Qianhui Qu, Deniz Aydin, Ouliana Panova, Michael J. Robertson, Yan Xu, Ron O. Dror, Georgios Skiniotis, Liang Feng

Nature. Author manuscript; available in PMC 2022 Sep 17.

Published in final edited form as: Nature. 2022 Jan; 601(7892): 274–279. Published online 2021 Dec 8. doi: 10.1038/s41586-021-04211-w

PMCID:: PMC9482448

Abstract Article PDF–7.7M

Select item 84101065.

miR-29a, b, and c regulate SLC5A8 expression in intestinal epithelial cells

Arivarasu N. Anbazhagan, Shubha Priyamvada, Anoop Kumar, Dulari Jayawardena, Alip Borthakur, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai, Pradeep K. Dudeja

Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1; 321(2): G223–G231. Published online 2021 Jul 7. doi: 10.1152/ajpgi.00148.2021

PMCID:: PMC8410106

Abstract Article

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 64384207.

Sodium-coupled monocarboxylate transporter is a target of epigenetic repression in cervical cancer

Jennifer Hernández-Juárez, Orlando Vargas-Sierra, Luis A. Herrera, David Cantú De León, Jorge Fernández-Retana, Carlos Pérez-Plasencia, César López-Camarillo, Patricio Gariglio, José Díaz-Chávez

Int J Oncol. 2019 May; 54(5): 1613–1624. Published online 2019 Mar 14. doi: 10.3892/ijo.2019.4749

PMCID:: PMC6438420

Abstract Article PDF–1.3M

Select item 57441858.

Iodide Binding in Sodium-Coupled Cotransporters

Ariela Vergara-Jaque, Peying Fong, Jeffrey Comer

J Chem Inf Model. 2017 Dec 26; 57(12): 3043–3055. Published online 2017 Nov 13. doi: 10.1021/acs.jcim.7b00521

PMCID:: PMC5744185

Abstract Article PDF–6.0M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 513307110.

Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery

Brian A. Irving, G. Craig Wood, Peter N. Bennotti, Ellappan Babu, Abhishek Deshpande, Michelle R. Lent, Anthony Petrick, Jon Gabrielsen, William Strodel, Glenn S. Gerhard, Christopher D. Still, Vadivel Ganapathy, David D. K. Rolston

Nutrients. 2016 Nov; 8(11): 683. Published online 2016 Oct 29. doi: 10.3390/nu8110683

PMCID:: PMC5133071

Abstract Article PDF–526K

Select item 513058711.

Insulin and SGK1 reduce the function of Na⁺/monocarboxylate transporter 1 (SMCT1/SLC5A8)

Adriana López-Barradas, Tania González-Cid, Norma Vázquez, Marisol Gavi-Maza, Adriana Reyes-Camacho, Laura A. Velázquez-Villegas, Victoria Ramírez, Kambiz Zandi-Nejad, David B. Mount, Nimbe Torres, Armando R. Tovar, Michael F. Romero, Gerardo Gamba, Consuelo Plata

Am J Physiol Cell Physiol. 2016 Nov 1; 311(5): C720–C734. Published online 2016 Aug 3. doi: 10.1152/ajpcell.00104.2015

PMCID:: PMC5130587

Abstract Article

Select item 459330412.

SLC5A8 Nuclear Translocation and Loss of Expression are Associated With Poor Outcome in Pancreatic Ductal Adenocarcinoma

James Helm, Domenico Coppola, Vadivel Ganapathy, Mark Lloyd, Barbara A. Centeno, Dung-Tsa Chen, Mokenge P. Malafa, Jong Y. Park

Pancreas. Author manuscript; available in PMC 2015 Oct 5.

Published in final edited form as: Pancreas. 2012 Aug; 41(6): 904–909. doi: 10.1097/MPA.0b013e31823f429f

PMCID:: PMC4593304

Abstract Article PDF–942K

Select item 381186813.

Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

Selvakumar Elangovan, Rajneesh Pathania, Sabarish Ramachandran, Sudha Ananth, Ravi N. Padia, Sonne R. Srinivas, Ellappan Babu, Lesleyann Hawthorn, Patricia V. Schoenlein, Thomas Boettger, Sylvia B. Smith, Puttur D. Prasad, Vadivel Ganapathy, Muthusamy Thangaraju

Mol Cell Biol. 2013 Oct; 33(19): 3920–3935. doi: 10.1128/MCB.01702-12

PMCID:: PMC3811868

Abstract Article PDF–3.6M

Select item 377350514.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 371045515.

The plasma membrane transporter SLC5A8 suppresses tumor progression through depletion of survivin without involving its transport function

Veena Coothankandaswamy, Selvakumar Elangovan, Nagendra Singh, Puttur D. Prasad, Muthusamy Thangaraju, Vadivel Ganapathy

Biochem J. Author manuscript; available in PMC 2013 Nov 15.

Published in final edited form as: Biochem J. 2013 Feb 15; 450(1): 169–178. doi: 10.1042/BJ20121248

PMCID:: PMC3710455

Abstract Article PDF–4.0M

Select item 356633216.

Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer

Jong Y. Park, Donghwa Kim, Mihi Yang, Hyun Y. Park, Sang Haak Lee, Maria Rincon, Jenny Kreahling, Christoph Plass, Dominic J. Smiraglia, Melvyn S. Tockman, Seung Joon Kim

Lung Cancer. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Lung Cancer. 2013 Mar; 79(3): 198–204. Published online 2012 Dec 27. doi: 10.1016/j.lungcan.2012.11.019

PMCID:: PMC3566332

Abstract Article PDF–978K

Select item 319003917.

Protein expressions and genetic variations of SLC5A8 in prostate cancer risk and aggressiveness

Hui-Yi Lin, Hyun Y. Park, Selina Radlein, Nupam P. Mahajan, Thomas A Sellers, Babu Zachariah, Julio Pow-Sang, Domenico Coppola, Vadivel Ganapathy, Jong Y. Park

Urology. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Urology. 2011 Oct; 78(4): 971.e1–971.e9. Published online 2011 Jul 29. doi: 10.1016/j.urology.2011.04.055

PMCID:: PMC3190039

Abstract Article PDF–1.1M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311057919.

SLC5A8 Gene, A Transporter of Butyrate: A Gut Flora Metabolite, Is Frequently Methylated in African American Colon Adenomas

Hassan Brim, Krishan Kumar, Javad Nazarian, Yetrib Hathout, Amir Jafarian, Edward Lee, William Green, Duane Smoot, Jong Park, Mehdi Nouraie, Hassan Ashktorab

PLoS One. 2011; 6(6): e20216. Published online 2011 Jun 8. doi: 10.1371/journal.pone.0020216

PMCID:: PMC3110579

Abstract Article PDF–295K

Select item 295733520.

The probiotic Lactobacillus plantarum counteracts TNF-α-induced downregulation of SMCT1 expression and function

Alip Borthakur, Arivarasu N. Anbazhagan, Anoop Kumar, Geetu Raheja, Varsha Singh, Krishnamurthy Ramaswamy, Pradeep K. Dudeja

Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4): G928–G934. Published online 2010 Jul 29. doi: 10.1152/ajpgi.00279.2010

PMCID:: PMC2957335

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