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Select item 108152591.

First Evidence of Mineralocorticoid Receptor Gene and Protein Expression in Rat and Human Thyroid Tissues and Cell Cultures

Jacopo Manso, Maria Chiara Pedron, Alberto Mondin, Simona Censi, Gianmaria Pennelli, Francesca Galuppini, Susi Barollo, Loris Bertazza, Claudia Maria Radu, Francesca Ghini, Paolo Simioni, Chiara Sabbadin, Filippo Ceccato, Decio Armanini, Caterina Mian

Int J Mol Sci. 2024 Jan; 25(2): 754. Published online 2024 Jan 6. doi: 10.3390/ijms25020754

PMCID:: PMC10815259

Abstract Article PDF–24M

Select item 107896682.

Mineralocorticoid receptor overactivation: targeting systemic impact with non-steroidal mineralocorticoid receptor antagonists

Gianluigi Savarese, Felix Lindberg, Gerasimos Filippatos, Javed Butler, Stefan D. Anker

Diabetologia. 2024; 67(2): 246–262. Published online 2023 Dec 21. doi: 10.1007/s00125-023-06031-1

PMCID:: PMC10789668

Abstract Article PDF–989K

Select item 106942943.

Effects of environmental and genetic interactions on job burnout in coal miners: interactions between occupational stress, coping styles, and NR3C2 gene polymorphisms

Xin Lin, Xiaofan Ma, Xiaoting Yi, Chao Qu, Fuye Li

Front Public Health. 2023; 11: 1237843. Published online 2023 Nov 20. doi: 10.3389/fpubh.2023.1237843

PMCID:: PMC10694294

Abstract Article PDF–245K

Select item 101786374.

Mineralocorticoid Receptor Antagonists for Preventing Chronic Kidney Disease Progression: Current Evidence and Future Challenges

Wataru Fujii, Shigeru Shibata

Int J Mol Sci. 2023 May; 24(9): 7719. Published online 2023 Apr 23. doi: 10.3390/ijms24097719

PMCID:: PMC10178637

Abstract Article PDF–750K

Select item 101536825.

Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients

Alice G. Vassiliou, Dimitra A. Vassiliadi, Chrysi Keskinidou, Edison Jahaj, Efi Botoula, Stylianos Tsagarakis, Anastasia Kotanidou, Ioanna Dimopoulou

Clin Med Res. 2023 Mar; 21(1): 6–13. doi: 10.3121/cmr.2023.1743

PMCID:: PMC10153682

Abstract Article PDF–1.1M

Select item 100983006.

NR3C2 inhibits the proliferation of colorectal cancer via regulating glucose metabolism and phosphorylating AMPK

Hui Liu, Wenqi Lei, Zhigui Li, Xiaodong Wang, Liming Zhou

J Cell Mol Med. 2023 Apr; 27(8): 1069–1082. Published online 2023 Mar 23. doi: 10.1111/jcmm.17706

PMCID:: PMC10098300

Abstract Article PDF–5.0M

Select item 99022177.

Emerging vascular cell-specific roles for mineralocorticoid receptor: implications for understanding sex differences in cardiovascular disease

Nicole L. Wolter, Iris Z. Jaffe

Am J Physiol Cell Physiol. 2023 Jan 1; 324(1): C193–C204. Published online 2022 Nov 28. doi: 10.1152/ajpcell.00372.2022

PMCID:: PMC9902217

Abstract Article

Select item 98198248.

Impact of Mineralocorticoid Receptor Gene NR3C2 on the Prediction of Functional Classification of Left Ventricular Remodeling and Arrhythmia after Acute Myocardial Infarction

Rima Braukyliene, Ali Aldujeli, Ayman Haq, Laurynas Maciulevicius, Darija Jankauskaite, Martynas Jurenas, Ramunas Unikas, Vytautas Zabiela, Vaiva Lesauskaite, Sandrita Simonyte, Diana Zaliaduonytė

Int J Environ Res Public Health. 2023 Jan; 20(1): 12. Published online 2022 Dec 20. doi: 10.3390/ijerph20010012

PMCID:: PMC9819824

Abstract Article PDF–810K

Select item 89083469.

NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Jia Li, Zhao Xu

Mol Med Rep. 2022 Apr; 25(4): 133. Published online 2022 Feb 18. doi: 10.3892/mmr.2022.12649

PMCID:: PMC8908346

Abstract Article PDF–7.6M

Select item 860116110.

Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis

Joshua J Man, Qing Lu, M. Elizabeth Moss, Brigett Carvajal, Wendy Baur, Amanda E Garza, Roy Freeman, Marina Anastasiou, Njabulo Ngwenyama, Gail K Adler, Pilar Alcaide, Iris Z Jaffe

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Nov; 41(11): 2740–2755. Published online 2021 Oct 7. doi: 10.1161/ATVBAHA.121.316929

PMCID:: PMC8601161

Abstract Article PDF–1.8M

Select item 827480811.

The Cardiac Mineralocorticoid Receptor (MR): A Therapeutic Target Against Ventricular Arrhythmias

Michel F. Rossier

Front Endocrinol (Lausanne) 2021; 12: 694758. Published online 2021 Jun 28. doi: 10.3389/fendo.2021.694758

PMCID:: PMC8274808

Abstract Article PDF–728K

Select item 824494612.

Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5

Jakob Hartmann, Thomas Bajaj, Claudia Klengel, Chris Chatzinakos, Tim Ebert, Nina Dedic, Kenneth M. McCullough, Roy Lardenoije, Marian Joëls, Onno C. Meijer, Katharine E. McCann, Serena M. Dudek, R. Angela Sarabdjitsingh, Nikolaos P. Daskalakis, Torsten Klengel, Nils C. Gassen, Mathias V. Schmidt, Kerry J. Ressler

Cell Rep. Author manuscript; available in PMC 2021 Jun 30.

Published in final edited form as: Cell Rep. 2021 Jun 1; 35(9): 109185. doi: 10.1016/j.celrep.2021.109185

PMCID:: PMC8244946

Abstract Article PDF–3.2M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800904814.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 786745015.

Jianjun Lu, Fang Hu, Yingling Zhou

Biomed Res Int. 2021; 2021: 9025481. Published online 2021 Jan 28. doi: 10.1155/2021/9025481

PMCID:: PMC7867450

Abstract Article PDF–15M

Select item 785193716.

CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer

Ya Fan, Jia Wang, Wen Jin, Yifei Sun, Yuemei Xu, Yipin Wang, Xiubin Liang, Dongming Su

Mol Cancer. 2021; 20: 25. Published online 2021 Feb 2. doi: 10.1186/s12943-021-01321-x

PMCID:: PMC7851937

Abstract Article PDF–11M

Select item 750701317.

Functional polymorphisms of the mineralocorticoid receptor gene NR3C2 are associated with diminished memory decline: Results from a longitudinal general‐population study

Jan Terock, Sandra Van der Auwera, Deborah Janowitz, Katharina Wittfeld, Alexander Teumer, Hans J. Grabe

Mol Genet Genomic Med. 2020 Sep; 8(9): e1345. Published online 2020 Jun 18. doi: 10.1002/mgg3.1345

PMCID:: PMC7507013

Abstract Article PDF–1014K

Select item 744712418.

GENETIC RISK FACTORS IN SEVERE, NONSEVERE AND ACUTE PHENOTYPES OF CENTRAL SEROUS CHORIORETINOPATHY

Danial Mohabati, Rosa L. Schellevis, Elon H. C. van Dijk, Sascha Fauser, Anneke I. den Hollander, Carel B. Hoyng, Eiko K. De Jong, Suzanne Yzer, Camiel J. F. Boon

Retina. 2020 Sep; 40(9): 1734–1741. Published online 2019 Dec 5. doi: 10.1097/IAE.0000000000002682

PMCID:: PMC7447124

Abstract Article PDF–440K

Select item 744474019.

Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan

Nadine Parker, Didac Vidal-Pineiro, Leon French, Jean Shin, Hieab H H Adams, Henry Brodaty, Simon R Cox, Ian J Deary, Anders M Fjell, Stefan Frenzel, Hans Grabe, Norbert Hosten, Mohammad Arfan Ikram, Jiyang Jiang, Maria J Knol, Bernard Mazoyer, Aniket Mishra, Perminder S Sachdev, Giovanni Salum, Claudia L Satizabal, Helena Schmidt, Reinhold Schmidt, Sudha Seshadri, Gunter Schumann, Henry Völzke, Kristine B Walhovd, Wei Wen, Katharina Wittfeld, Qiong Yang, Stephanie Debette, Zdenka Pausova, Tomáš Paus

Cereb Cortex. 2020 Mar; 30(2): 575–586. Published online 2019 Jun 26. doi: 10.1093/cercor/bhz108

PMCID:: PMC7444740

Abstract Article PDF–793K

Select item 692258920.

NR3C2 gene polymorphism is associated with risk of gestational hypertension in Han Chinese women

Zhenghui Cui, Jianyun Xu, Wenying Jiang

Medicine (Baltimore) 2019 Dec; 98(50): e18215. Published online 2019 Dec 16. doi: 10.1097/MD.0000000000018215

PMCID:: PMC6922589

Abstract Article PDF–666K

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