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Select item 106415241.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 106277862.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 103531163.

Elevated FAM134B expression induces radiation-sensitive in hepatocellular carcinoma

Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu, Heping Li

BMC Cancer. 2023; 23: 671. Published online 2023 Jul 17. doi: 10.1186/s12885-023-11030-x

PMCID:: PMC10353116

Abstract Article PDF–3.1M

Select item 102473664.

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum

Alexis González, Adriana Covarrubias-Pinto, Ramachandra M. Bhaskara, Marius Glogger, Santosh K. Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E. Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A. Schulman, Michael M. Kessels, Christian A. Hübner, Mike Heilemann, Gerhard Hummer, Ivan Dikić

Nature. 2023; 618(7964): 394–401. Published online 2023 May 24. doi: 10.1038/s41586-023-06089-2

PMCID:: PMC10247366

Abstract Article PDF–24M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101037876.

A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy

Xinyi Wang, Xiao Jiang, Boran Li, Jiahua Zheng, Jiansheng Guo, Lei Gao, Mengjie Du, Xialian Weng, Lin Li, She Chen, Jingzi Zhang, Lei Fang, Ting Liu, Liang Wang, Wei Liu, Dante Neculai, Qiming Sun

J Cell Biol. 2023 May 1; 222(5): e202201068. Published online 2023 Apr 12. doi: 10.1083/jcb.202201068

PMCID:: PMC10103787

Abstract Article PDF–6.2M

Select item 100339377.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 99982908.

Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication

Xuan Tan, Kun Cai, Jiajia Li, Zhen Yuan, Ruifeng Chen, Hurong Xiao, Chuanrui Xu, Bing Hu, Yali Qin, Binbin Ding

Cell Rep. 2023 Apr 25; 42(4): 112286. Published online 2023 Mar 10. doi: 10.1016/j.celrep.2023.112286

PMCID:: PMC9998290

Abstract Article PDF–7.6M

Select item 96290879.

SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection

Xiaolin Zhang, Ziwei Yang, Ting Pan, Xubing Long, Qinqin Sun, Pei-Hui Wang, Xiaojuan Li, Ersheng Kuang

Autophagy. 2022; 18(11): 2576–2592. Published online 2022 Mar 3. doi: 10.1080/15548627.2022.2039992

PMCID:: PMC9629087

Abstract Article PDF–2.4M

Select item 934857610.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 903755412.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 840877013.

Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1

Pratima Rawat, Sean S Brummel, Kumud K Singh, Jihoon Kim, Kelly A Frazer, Sharon Nichols, George R Seage, III, Paige L Williams, Russell B Van Dyke, Olivier Harismendy, Rodney N Trout, Stephen A Spector

J Infect Dis. 2021 Sep 1; 224(5): 870–880. Published online 2020 Dec 29. doi: 10.1093/infdis/jiaa792

PMCID:: PMC8408770

Abstract Article PDF–2.3M

Select item 836346114.

FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

Rongjin Luo, Shuai Li, Gaocai Li, Saideng Lu, Weifeng Zhang, Hui Liu, Jie Lei, Liang Ma, Wencan Ke, Zhiwei Liao, Bingjin Wang, Yu Song, Kun Wang, Yukun Zhang, Cao Yang

Oxid Med Cell Longev. 2021; 2021: 3843145. Published online 2021 Aug 5. doi: 10.1155/2021/3843145

PMCID:: PMC8363461

Abstract Article PDF–4.0M

Select item 835459715.

RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism

Debdatto Mookherjee, Subhrangshu Das, Rukmini Mukherjee, Manindra Bera, Swadhin Chandra Jana, Saikat Chakrabarti, Oishee Chakrabarti

Autophagy. 2021; 17(7): 1729–1752. Published online 2020 Jul 1. doi: 10.1080/15548627.2020.1783118

PMCID:: PMC8354597

Abstract Article PDF–25M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 786424417.

Differential expression of full-length and NH₂ terminally truncated FAM134B isoforms in normal physiology and cancer

Umur Keles, Evin Iscan, Huriye Erbak Yilmaz, Gökhan Karakülah, Aslı Suner, Erhan Bal, Nilgun Tasdemir, Ayse Derya Cavga, Umut Ekin, Zeynep Mutlu, Sila Kahyaoglu, Muhittin A. Serdar, Nese Atabey, Mehmet Ozturk

Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1; 319(6): G733–G747. Published online 2020 Oct 14. doi: 10.1152/ajpgi.00094.2020

PMCID:: PMC7864244

Abstract Article

Select item 773267718.

Novel exomic rare variants associated with venous thrombosis

Hiroshi Deguchi, Meenal Shukla, Mohammed Hayat, Ali Torkamani, Darlene J. Elias, John H. Griffin

Br J Haematol. Author manuscript; available in PMC 2020 Dec 11.

Published in final edited form as: Br J Haematol. 2020 Sep; 190(5): 783–786. Published online 2020 Mar 30. doi: 10.1111/bjh.16613

PMCID:: PMC7732677

Abstract Article PDF–108K

Select item 758349419.

Overexpression of family with sequence similarity 134, member B (FAM134B) in colon cancers and its tumor suppressive properties in vitro

Katherine Ting-Wei Lee, Farhadul Islam, Jelena Vider, Jeremy Martin, Anna Chruścik, Cu-Tai Lu, Vinod Gopalan, Alfred King-yin Lam

Cancer Biol Ther. 2020; 21(10): 954–962. Published online 2020 Aug 28. doi: 10.1080/15384047.2020.1810535

PMCID:: PMC7583494

Abstract Article PDF–2.1M

Select item 745942620.

MiT/TFE factors control ER‐phagy via transcriptional regulation of FAM134B

Laura Cinque, Chiara De Leonibus, Maria Iavazzo, Natalie Krahmer, Daniela Intartaglia, Francesco Giuseppe Salierno, Rossella De Cegli, Chiara Di Malta, Maria Svelto, Carmela Lanzara, Marianna Maddaluno, Luca Giorgio Wanderlingh, Antje K Huebner, Marcella Cesana, Florian Bonn, Elena Polishchuk, Christian A Hübner, Ivan Conte, Ivan Dikic, Matthias Mann, Andrea Ballabio, Francesca Sacco, Paolo Grumati, Carmine Settembre

EMBO J. 2020 Sep 1; 39(17): e105696. Published online 2020 Jul 27. doi: 10.15252/embj.2020105696

PMCID:: PMC7459426

Abstract Article PDF–4.1M

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PMC Links for GEO Profiles (Select 98672663) (45)
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Nucleotide Links for PMC (Select 3121735) (100)
Nucleotide
Conserved Domain Links for Protein (Select 255740203) (1)
Conserved Domains
Pan troglodytes verus DNA, chromosome Y, partial sequence
Pan troglodytes verus DNA, chromosome Y, partial sequence
gi|93004748|dbj|BA000047.1|

Nucleotide
Aesculus chinensis voucher XA084 small subunit ribosomal RNA gene, partial seque...
Aesculus chinensis voucher XA084 small subunit ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and large subunit ribosomal RNA gene, partial sequence
gi|1441206754|gb|MH711820.1|

Nucleotide

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