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Select item 111616321.

SNX16 is required for hepatocellular carcinoma survival via modulating the EGFR-AKT signaling pathway

Lebin Yuan, Yanqiu Meng, Jiajia Xiang

Sci Rep. 2024; 14: 13093. Published online 2024 Jun 7. doi: 10.1038/s41598-024-64015-6

PMCID:: PMC11161632

Abstract Article PDF–17M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73467263.

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

Kristina N. Schaefer, Mira I. Pronobis, Clara E. Williams, Shiping Zhang, Lauren Bauer, Dennis Goldfarb, Feng Yan, M. Ben Major, Mark Peifer

Mol Biol Cell. 2020 May 1; 31(10): 992–1014. doi: 10.1091/mbc.E19-11-0647

PMCID:: PMC7346726

Abstract Article PDF–5.5M

Select item 69986594.

SNX16 activates c‐Myc signaling by inhibiting ubiquitin‐mediated proteasomal degradation of eEF1A2 in colorectal cancer development

Zhiyong Shen, Yongsheng Li, Yuan Fang, Mingdao Lin, Xiaochuang Feng, Zhenkang Li, Yizhi Zhan, Yuechen Liu, Tingyu Mou, Xiaoliang Lan, Yanan Wang, Guoxin Li, Jiping Wang, Haijun Deng

Mol Oncol. 2020 Feb; 14(2): 387–406. Published online 2020 Jan 10. doi: 10.1002/1878-0261.12626

PMCID:: PMC6998659

Abstract Article PDF–8.5M

Select item 60777225.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 47645737.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning

Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich

eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466

PMCID:: PMC4764573

Abstract Article PDF–5.7M

Select item 46479418.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 46172119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 423074510.

SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells

Leilei Zhang, Dajiang Qin, Chunfang Hao, Xiaodong Shu, Duanqing Pei

Cell Regen. 2013; 2: 3. Published online 2013 Apr 30. doi: 10.1186/2045-9769-2-3

PMCID:: PMC4230745

Abstract Article PDF–1.5M

Select item 409198611.

Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases

Joanna Cobb, Erika Cule, Halima Moncrieffe, Anne Hinks, Simona Ursu, Fiona Patrick, Laura Kassoumeri, Edward Flynn, Maja Bulatovic, Nico Wulffraat, Bertrand van Zelst, Robert de Jonge, Marek Bohm, Pavla Dolezalova, Shashi Hirani, Stanton Newman, Pamela Whitworth, Taunton R Southwood, Childhood Arthritis Response to Medication Study (CHARMS), Childhood Arthritis Prospective Study (CAPS), BSPAR study group, Maria De Iorio, Lucy R Wedderburn, Wendy Thomson

Pharmacogenomics J. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Pharmacogenomics J. 2014 Aug; 14(4): 356–364. Published online 2014 Apr 8. doi: 10.1038/tpj.2014.3

PMCID:: PMC4091986

Abstract Article PDF–513K

Select item 369318312.

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Paul D. P. Pharoah, Ya-Yu Tsai, Susan J. Ramus, Catherine M. Phelan, Ellen L. Goode, Kate Lawrenson, Melissa Price, Brooke L. Fridley, Jonathan P. Tyrer, Howard Shen, Rachel Weber, Rod Karevan, Melissa C. Larson, Honglin Song, Daniel C. Tessier, François Bacot, Daniel Vincent, Julie M. Cunningham, Joe Dennis, Ed Dicks, Australian Cancer Study, Australian Ovarian Cancer Study Group, Katja K. Aben, Hoda Anton-Culver, Natalia Antonenkova, Sebastian M. Armasu, Laura Baglietto, Elisa V. Bandera, Matthias W. Beckmann, Michael J. Birrer, Greg Bloom, Natalia Bogdanova, James D. Brenton, Louise A. Brinton, Angela Brooks-Wilson, Robert Brown, Ralf Butzow, Ian Campbell, Michael E Carney, Renato S. Carvalho, Jenny Chang-Claude, Y. Anne Chen, Zhihua Chen, Wong-Ho Chow, Mine S. Cicek, Gerhard Coetzee, Linda S. Cook, Daniel W. Cramer, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Diana Eccles, Robert Edwards, Arif B. Ekici, Peter A. Fasching, David Fenstermacher, James Flanagan, Yu-Tang Gao, Montserrat Garcia-Closas, Aleksandra Gentry-Maharaj, Graham Giles, Anxhela Gjyshi, Martin Gore, Jacek Gronwald, Qi Guo, Mari K Halle, Philipp Harter, Alexander Hein, Florian Heitz, Peter Hillemanns, Maureen Hoatlin, Estrid Høgdall, Claus K. Høgdall, Satoyo Hosono, Anna Jakubowska, Allan Jensen, Kimberly R. Kalli, Beth Y. Karlan, Linda E. Kelemen, Lambertus A. Kiemeney, Susanne Krüger Kjaer, Gottfried E. Konecny, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Nathan Lee, Janet Lee, Arto Leminen, Boon Kiong Lim, Jolanta Lissowska, Jan Lubinski, Lene Lundvall, Galina Lurie, Leon F.A.G. Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Usha Menon, Francesmary Modugno, Kirsten B. Moysich, Toru Nakanishi, Steven A. Narod, Roberta B. Ness, Heli Nevanlinna, Stefan Nickels, Houtan Noushmehr, Kunle Odunsi, Sara Olson, Irene Orlow, James Paul, Tanja Pejovic, Liisa M Pelttari, Jenny Permuth-Wey, Malcolm C Pike, Elizabeth M Poole, Xiaotao Qu, Harvey A. Risch, Lorna Rodriguez-Rodriguez, Mary Anne Rossing, Anja Rudolph, Ingo Runnebaum, Iwona K Rzepecka, Helga B. Salvesen, Ira Schwaab, Gianluca Severi, Hui Shen, Vijayalakshmi Shridhar, Xiao-Ou Shu, Weiva Sieh, Melissa C. Southey, Paul Spellman, Kazuo Tajima, Soo-Hwang Teo, Kathryn L. Terry, Pamela J Thompson, Agnieszka Timorek, Shelley S. Tworoger, Anne M. van Altena, David Van Den Berg, Ignace Vergote, Robert A. Vierkant, Allison F. Vitonis, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Elisabeth Wik, Boris Winterhoff, Yin Ling Woo, Anna H Wu, Hannah P. Yang, Wei Zheng, Argyrios Ziogas, Famida Zulkifli, Marc T. Goodman, Per Hall, Douglas F Easton, Celeste L Pearce, Andrew Berchuck, Georgia Chenevix-Trench, Edwin Iversen, Alvaro N.A. Monteiro, Simon A. Gayther, Joellen M. Schildkraut, Thomas A. Sellers

Nat Genet. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Nat Genet. 2013 Apr; 45(4): 362–370e2. doi: 10.1038/ng.2564

PMCID:: PMC3693183

Abstract Article PDF–977K

Select item 329186313.

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants

Sha Tao, Zhong Wang, Junjie Feng, Fang-Chi Hsu, Guangfu Jin, Seong-Tae Kim, Zheng Zhang, Henrik Gronberg, Lilly S. Zheng, William B. Isaacs, Jianfeng Xu, Jielin Sun

Carcinogenesis. 2012 Mar; 33(3): 598–603. Published online 2012 Jan 4. doi: 10.1093/carcin/bgr316

PMCID:: PMC3291863

Abstract Article PDF–109K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313077015.

Role of SNX16 in the Dynamics of Tubulo-Cisternal Membrane Domains of Late Endosomes

Ben Brankatschk, Véronique Pons, Robert G. Parton, Jean Gruenberg

PLoS One. 2011; 6(7): e21771. Published online 2011 Jul 6. doi: 10.1371/journal.pone.0021771

PMCID:: PMC3130770

Abstract Article PDF–2.6M

Select item 302569516.

The Association of Genome-Wide Variation with the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis from the CHARGE Consortium

Nicholas L. Smith, Janine F. Felix, Alanna C. Morrison, Serkalem Demissie, Nicole L. Glazer, Laura R. Loehr, L. Adrienne Cupples, Abbas Dehghan, Thomas Lumley, Wayne D. Rosamond, Wolfgang Lieb, Fernando Rivadeneira, Joshua C. Bis, Aaron R. Folsom, Emelia Benjamin, Yurii S. Aulchenko, Talin Haritunians, David Couper, Joanne Murabito, Ying A. Wang, Bruno H. Stricker, John S. Gottdiener, Patricia P. Chang, Thomas J. Wang, Kenneth M. Rice, Albert Hofman, Susan R. Heckbert, Ervin R. Fox, Christopher J. O’Donnell, Andre G. Uitterlinden, Jerome I. Rotter, James T. Willerson, Daniel Levy, Cornelia M. van Duijn, Bruce M. Psaty, Jacqueline C. M. Witteman, Eric Boerwinkle, Ramachandran S. Vasan

Circ Cardiovasc Genet. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2010 Jun 1; 3(3): 256–266. Published online 2010 May 5. doi: 10.1161/CIRCGENETICS.109.895763

PMCID:: PMC3025695

Abstract Article PDF–602K

Select item 275175117.

Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study

Christiane Wolf, Eugen Gramer, Bertram Müller-Myhsok, Francesca Pasutto, Eva Reinthal, Bernd Wissinger, Nicole Weisschuh

BMC Med Genet. 2009; 10: 91. Published online 2009 Sep 15. doi: 10.1186/1471-2350-10-91

PMCID:: PMC2751751

Abstract Article PDF–249K

Select item 268304718.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 122225320.

The Phox homology (PX) domain, a new player in phosphoinositide signalling.

Y Xu, L F Seet, B Hanson, W Hong

Biochem J. 2001 Dec 15; 360(Pt 3): 513–530. doi: 10.1042/0264-6021:3600513

PMCID:: PMC1222253

Summary PDF–657K

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