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Select item 112242941.

SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation

Martina Morelli, Stefania Madonna, Cristina Albanesi

Front Immunol. 2024; 15: 1393799. Published online 2024 Jun 21. doi: 10.3389/fimmu.2024.1393799

PMCID:: PMC11224294

Abstract Article PDF–1.4M

Select item 109634512.

Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease

Mariaenrica Tinè, Elisabetta Balestro, Sara Carpi, Tommaso Neri, Davide Biondini, Maria Conti, Alvise Casara, Nicol Bernardinello, Elisabetta Cocconcelli, Graziella Turato, Simonetta Baraldo, Alessandro Celi, Paolo Spagnolo, Manuel G. Cosio, Marina Saetta, Erica Bazzan

Front Immunol. 2024; 15: 1320077. Published online 2024 Mar 12. doi: 10.3389/fimmu.2024.1320077

PMCID:: PMC10963451

Abstract Article PDF–1.6M

Select item 109131213.

SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse

Xin Jin, Qing Hu, Meiying Qin, Yitong Yin, Zhijun Xia

Balkan Med J. 2024 Mar; 41(2): 105–112. Published online 2024 Mar 1. doi: 10.4274/balkanmedj.galenos.2023.2023-10-60

PMCID:: PMC10913121

Abstract Article PDF–2.3M

Select item 109091044.

Suppressor of Cytokine Signaling-3 Gene Polymorphisms and the Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Patients in Egypt

Amal El Sharnoby, Hanan M Bedair, Gamal Yousef S Raia, Nermeen Hamed, Aliaa Sabry, Fatma A. Khalaf, Mohamed Rashed Abd Elhamed, Mohamed Abdel-Samiee

Asian Pac J Cancer Prev. 2023; 24(12): 4253–4261. doi: 10.31557/APJCP.2023.24.12.4253

PMCID:: PMC10909104

Abstract Article PDF–856K

Select item 107924255.

Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes

Chi-Wei Liu, Hsuan-Yu Peng, An-Ci Siao, Yi-Wei Tsuei, Yen-Yue Lin, Shine-Gwo Shiah, Li-Jane Shih, Chien-Chih Yeh, Shih-Wei Lee, Yung-Hsi Kao

Exp Biol Med (Maywood) 2023 Oct; 248(20): 1695–1707. Published online 2023 Aug 30. doi: 10.1177/15353702231191206

PMCID:: PMC10792425

Abstract Article PDF–3.2M

Select item 105907016.

Enterovirus D68 infection upregulates SOCS3 expression to inhibit JAK-STAT3 signaling and antagonize the innate interferon response of the host

Yuling Zhang, Leling Xu, Zhe Zhang, Xin Su, Zhiyun Wang, Tao Wang

Virol Sin. 2023 Oct; 38(5): 755–766. Published online 2023 Aug 30. doi: 10.1016/j.virs.2023.08.007

PMCID:: PMC10590701

Abstract Article PDF–4.5M

Select item 104572957.

DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood

Prachand Issarapu, Manisha Arumalla, Hannah R. Elliott, Suraj S. Nongmaithem, Alagu Sankareswaran, Modupeh Betts, Sara Sajjadi, Noah J. Kessler, Swati Bayyana, Sohail R. Mansuri, Maria Derakhshan, G. V. Krishnaveni, Smeeta Shrestha, Kalyanaraman Kumaran, Chiara Di Gravio, Sirazul A. Sahariah, Eleanor Sanderson, Caroline L. Relton, Kate A. Ward, Sophie E. Moore, Andrew M. Prentice, Karen A. Lillycrop, Caroline H. D. Fall, Matt J. Silver, Giriraj R. Chandak, the EMPHASIS study group

Nat Commun. 2023; 14: 5200. Published online 2023 Aug 25. doi: 10.1038/s41467-023-40607-0

PMCID:: PMC10457295

Abstract Article PDF–1.7M

Select item 102391158.

Kremen2 drives the progression of non-small cell lung cancer by preventing SOCS3-mediated degradation of EGFR

Yuxiao Sun, Yu Gao, Mingxin Dong, Jiuzhen Li, Xin Li, Ningning He, Huijuan Song, Manman Zhang, Kaihua Ji, Jinhan Wang, Yeqing Gu, Yan Wang, Liqing Du, Yang Liu, Qin Wang, Hezheng Zhai, Daqiang Sun, Qiang Liu, Chang Xu

J Exp Clin Cancer Res. 2023; 42: 140. Published online 2023 Jun 3. doi: 10.1186/s13046-023-02692-3

PMCID:: PMC10239115

Abstract Article PDF–4.9M

Select item 102296329.

IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

Holly Bachus, Erin McLaughlin, Crystal Lewis, Amber M. Papillion, Etty N. Benveniste, Dave Durell Hill, Alexander F. Rosenberg, André Ballesteros-Tato, Beatriz León

Cell Mol Immunol. 2023 Jun; 20(6): 651–665. Published online 2023 Apr 12. doi: 10.1038/s41423-023-01012-1

PMCID:: PMC10229632

Abstract Article PDF–5.0M

Select item 1007083110.

SOCS3 as a potential driver of lung metastasis in colon cancer patients

Xuejie Li, Zuyi Yang, Bi Chen, Lei Gu, Guoyan Tian, Xinbing Sui

Front Immunol. 2023; 14: 1088542. Published online 2023 Mar 21. doi: 10.3389/fimmu.2023.1088542

PMCID:: PMC10070831

Abstract Article PDF–18M

Select item 993880911.

Tissue levels of suppressor of cytokine signaling-3 (SOCS-3) in mycosis fungoides

Hanan R. Nada, Laila A. Rashed, Ola Ouda Salman, Nermeen M. A. Abdallah, Mohamed M. Abdelhady

Arch Dermatol Res. 2023; 315(2): 165–171. Published online 2022 Feb 28. doi: 10.1007/s00403-022-02339-x

PMCID:: PMC9938809

Abstract Article PDF–680K

Select item 989140012.

Upregulated expression of FFAR2 and SOC3 genes is associated with gout

Oliver C Orji, Maria B López-Domínguez, Gabriela Sandoval-Plata, Tamar Guetta-Baranes, Ana M Valdes, Michael Doherty, Kevin Morgan, Abhishek Abhishek

Rheumatology (Oxford) 2023 Feb; 62(2): 977–983. Published online 2022 Jun 22. doi: 10.1093/rheumatology/keac360

PMCID:: PMC9891400

Abstract Article PDF–429K

Select item 981730213.

Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women

Solaleh Emamgholipour, Fataneh Esmaeili, Maryam Shabani, Seyedeh Zahra Hasanpour, Mahsa Pilehvari, Hossein Zabihi-Mahmoudabadi, Meysam Motevasseli, Mehrnoosh Shanaki

BMC Endocr Disord. 2023; 23: 7. Published online 2023 Jan 6. doi: 10.1186/s12902-022-01247-5

PMCID:: PMC9817302

Abstract Article PDF–1.2M

Select item 955514914.

Modulation of SOCS3 Levels via STAT3 and Estrogen-ERαp66 Signaling during Hepatitis E Virus Replication in Hepatocellular Carcinoma Cells

Harini Sooryanarain, C. Lynn Heffron, Hassan M. Mahsoub, Anna M. Hassebroek, Bo Wang, Debin Tian, S. Ansar Ahmed, Xiang-Jin Meng

J Virol. 2022 Oct; 96(19): e01008-22. Published online 2022 Sep 14. doi: 10.1128/jvi.01008-22

PMCID:: PMC9555149

Abstract Article PDF–2.7M

Select item 950336415.

Mendelian Randomization Analysis of the Association of SOCS3 Methylation with Abdominal Obesity

Yuqian Li, Xiaotian Liu, Runqi Tu, Jian Hou, Guihua Zhuang

Nutrients. 2022 Sep; 14(18): 3824. Published online 2022 Sep 16. doi: 10.3390/nu14183824

PMCID:: PMC9503364

Abstract Article PDF–274K

Select item 947688816.

Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis

Merve Özçep, Nilhan Atsü, Nilgün Solak, Sevim Karakaş Çelik

Immun Inflamm Dis. 2022 Oct; 10(10): e695. Published online 2022 Sep 15. doi: 10.1002/iid3.695

PMCID:: PMC9476888

Abstract Article PDF–1.0M

Select item 945496017.

SOCS3 Regulates Dectin-2-Induced Inflammation in PBMCs of Diabetic Patients

Mohammed J. A. Haider, Zahraa Albaqsumi, Fahd Al-Mulla, Rasheed Ahmad, Fatema Al-Rashed

Cells. 2022 Sep; 11(17): 2670. Published online 2022 Aug 28. doi: 10.3390/cells11172670

PMCID:: PMC9454960

Abstract Article PDF–2.6M

Select item 928622418.

Expression of mycobacterium tuberculosis induced SOCS3 and STAT3 and the implications on innate immunity in TB patients vs healthy contacts in high TB/HIV endemic setting: A cross-sectional analytical study

Patrick Lungu, Kabaso Mushota, Evarist Njelesani, Thomas Sukwa, Shabir Lakhi, Peter Mwaba

PLoS One. 2022; 17(7): e0263624. Published online 2022 Jul 15. doi: 10.1371/journal.pone.0263624

PMCID:: PMC9286224

Abstract Article PDF–1.4M

Select item 926261419.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 919619220.

Deciphering Obesity-Related Gene Clusters Unearths SOCS3 Immune Infiltrates and 5mC/m6A Modifiers in Ossification of Ligamentum Flavum Pathogenesis

Baoliang Zhang, Lei Yuan, Guanghui Chen, Xi Chen, Xiaoxi Yang, Tianqi Fan, Chuiguo Sun, Dongwei Fan, Zhongqiang Chen

Front Endocrinol (Lausanne) 2022; 13: 861567. Published online 2022 May 30. doi: 10.3389/fendo.2022.861567

PMCID:: PMC9196192

Abstract Article PDF–23M

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