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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78954012.

Subcellular localization of glypican-5 is associated with dynamic motility of the human mesenchymal stem cell line U3DT

Masao Takeuchi, Kikuko Takeuchi, Tomoyo Takai, Ritsuko Yamaguchi, Tetsushi Furukawa, Ken-ichi Akagi, Jun K. Takeuchi

PLoS One. 2021; 16(2): e0226538. Published online 2021 Feb 19. doi: 10.1371/journal.pone.0226538

PMCID:: PMC7895401

Abstract Article PDF–3.7M

Select item 78448403.

Overexpression of Glypican 5 (GPC5) Inhibits Prostate Cancer Cell Proliferation and Invasion via Suppressing Sp1-Mediated EMT and Activation of Wnt/β-Catenin Signaling

Yu Sun, Kai Xu, Miao He, Guilian Fan, Hongming Lu

Oncol Res. 2018; 26(4): 565–572. Published online 2018 May 7. doi: 10.3727/096504017X15044461944385

PMCID:: PMC7844840

Abstract Article PDF–5.9M

Select item 76571794.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 64961245.

miR‐297 acts as an oncogene by targeting GPC5 in lung adenocarcinoma

Yunchuan Sun, Jianyong Zhao, Xiaoming Yin, Xiangkun Yuan, Jianfei Guo, Jianqiang Bi

Cell Prolif. 2016 Oct; 49(5): 636–643. Published online 2016 Aug 24. doi: 10.1111/cpr.12288

PMCID:: PMC6496124

Abstract Article PDF–931K

Select item 64959816.

miR‐709 up‐regulated in hepatocellular carcinoma, promotes proliferation and invasion by targeting GPC5

Tonggang Liu, Xuezhong Zhang, Kaihui Sha, Xianxian Liu, Liguo Zhang, Bangmao Wang

Cell Prolif. 2015 Jun; 48(3): 330–337. Published online 2015 Mar 27. doi: 10.1111/cpr.12181

PMCID:: PMC6495981

Abstract Article PDF–1.8M

Select item 62034507.

Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

Cesare Orlandi, Yoshihiro Omori, Yuchen Wang, Yan Cao, Akiko Ueno, Michel J. Roux, Giuseppe Condomitti, Joris de Wit, Motoi Kanagawa, Takahisa Furukawa, Kirill A. Martemyanov

Cell Rep. Author manuscript; available in PMC 2018 Oct 26.

Published in final edited form as: Cell Rep. 2018 Oct 2; 25(1): 130–145.e5. doi: 10.1016/j.celrep.2018.08.068

PMCID:: PMC6203450

Abstract Article PDF–2.9M

Select item 53467478.

Glypican-5 suppresses Epithelial-Mesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a

Siwei Wang, Mantang Qiu, Wenjia Xia, Youtao Xu, Qixing Mao, Jie Wang, Gaochao Dong, Lin Xu, Xin Yang, Rong Yin

Oncotarget. 2016 Nov 29; 7(48): 79736–79746. Published online 2016 Oct 27. doi: 10.18632/oncotarget.12945

PMCID:: PMC5346747

Abstract Article PDF–6.4M

Select item 49744819.

Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal

Li Du, Yi-Jia Li, Marwan Fakih, Rebecca L. Wiatrek, Marjun Duldulao, Zhenbin Chen, Peiguo Chu, Julio Garcia-Aguilar, Yuan Chen

Nat Commun. 2016; 7: 12326. Published online 2016 Jul 28. doi: 10.1038/ncomms12326

PMCID:: PMC4974481

Abstract Article PDF–1.5M

Select item 442665610.

Polymorphisms in C-Reactive Protein and Glypican-5 Are Associated with Lung Cancer Risk and Gartrokine-1 Influences Cisplatin-Based Chemotherapy Response in a Chinese Han Population

Shuo Zhang, Asmitananda Thakur, Yiqian Liang, Ting Wang, Lei Gao, Tian Yang, Yang Li, Tingting Geng, Tianbo Jin, Tianjun Chen, Johnson J. Liu, Mingwei Chen

Dis Markers. 2015; 2015: 824304. Published online 2015 Apr 27. doi: 10.1155/2015/824304

PMCID:: PMC4426656

Abstract Article PDF–519K

Select item 440234811.

Gene–Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study

Yun J. Sung, Lisa de las Fuentes, Karen L. Schwander, Jeannette Simino, Dabeeru C. Rao

Am J Hypertens. 2015 Mar; 28(3): 343–354. Published online 2014 Sep 3. doi: 10.1093/ajh/hpu149

PMCID:: PMC4402348

Abstract Article PDF–38M

Select item 435137912.

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

Meian He, Min Xu, Ben Zhang, Jun Liang, Peng Chen, Jong-Young Lee, Todd A. Johnson, Huaixing Li, Xiaobo Yang, Juncheng Dai, Liming Liang, Lixuan Gui, Qibin Qi, Jinyan Huang, Yanping Li, Linda S. Adair, Tin Aung, Qiuyin Cai, Ching-Yu Cheng, Myeong-Chan Cho, Yoon Shin Cho, Minjie Chu, Bin Cui, Yu-Tang Gao, Min Jin Go, Dongfeng Gu, Weiqiong Gu, Huan Guo, Yongchen Hao, Jie Hong, Zhibin Hu, Yanling Hu, Jianfeng Huang, Joo-Yeon Hwang, Mohammad Kamran Ikram, Guangfu Jin, Dae-Hee Kang, Chiea Chuen Khor, Bong-Jo Kim, Hung Tae Kim, Michiaki Kubo, Jeannette Lee, Juyoung Lee, Nanette R. Lee, Ruoying Li, Jun Li, JianJun Liu, Jirong Longe, Wei Lu, Xiangfeng Lu, Xiaoping Miao, Yukinori Okada, Rick Twee-Hee Ong, Gaokun Qiu, Mark Seielstad, Xueling Sim, Huaidong Song, Fumihiko Takeuchi, Toshihiro Tanaka, Phil R. Taylor, Laiyuan Wang, Weiqing Wang, Yiqin Wang, Chen Wu, Ying Wu, Yong-Bing Xiang, Ken Yamamoto, Handong Yang, Ming Liao, Mitsuhiro Yokota, Terri Young, Xiaomin Zhang, Norihiro Kato, Qing K. Wang, Wei Zheng, Frank B. Hu, Dongxin Lin, Hongbing Shen, Yik Ying Teo, Zengnan Mo, Tien Yin Wong, Xu Lin, Karen L. Mohlke, Guang Ning, Tatsuhiko Tsunoda, Bok-Ghee Han, Xiao-Ou Shu, E. Shyong Tai, Tangchun Wu, Lu Qi

Hum Mol Genet. 2015 Mar 15; 24(6): 1791–1800. Published online 2014 Nov 26. doi: 10.1093/hmg/ddu583

PMCID:: PMC4351379

Abstract Article PDF–436K

Select item 433481413.

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

Sergio E. Baranzini, Joanne Wang, Rachel A. Gibson, Nicholas Galwey, Yvonne Naegelin, Frederik Barkhof, Ernst-Wilhelm Radue, Raija L.P. Lindberg, Bernard M.G. Uitdehaag, Michael R. Johnson, Aspasia Angelakopoulou, Leslie Hall, Jill C. Richardson, Rab K. Prinjha, Achim Gass, Jeroen J.G. Geurts, Jolijn Kragt, Madeleine Sombekke, Hugo Vrenken, Pamela Qualley, Robin R. Lincoln, Refujia Gomez, Stacy J. Caillier, Michaela F. George, Hourieh Mousavi, Rosa Guerrero, Darin T. Okuda, Bruce A. C. Cree, Ari J. Green, Emmanuelle Waubant, Douglas S. Goodin, Daniel Pelletier, Paul M. Matthews, Stephen L. Hauser, Ludwig Kappos, Chris H. Polman, Jorge R. Oksenberg

Hum Mol Genet. 2009 Feb 15; 18(4): 767–778. Published online 2008 Nov 14. doi: 10.1093/hmg/ddn388

PMCID:: PMC4334814

Abstract Article PDF–274K

Select item 379399114.

Multiple Sclerosis Susceptibility Genes: Associations with Relapse Severity and Recovery

Ellen M. Mowry, Robert F. Carey, Maria R. Blasco, Jean Pelletier, Pierre Duquette, Pablo Villoslada, Irina Malikova, Elaine Roger, R. Phillip Kinkel, Jamie McDonald, Peter Bacchetti, Emmanuelle Waubant

PLoS One. 2013; 8(10): e75416. Published online 2013 Oct 9. doi: 10.1371/journal.pone.0075416

PMCID:: PMC3793991

Abstract Article PDF–158K

Select item 376483115.

Heparan Sulfate Proteoglycans Containing a Glypican 5 Core and 2-O-Sulfo-iduronic Acid Function as Sonic Hedgehog Co-receptors to Promote Proliferation

Rochelle M. Witt, Marie-Lyn Hecht, Maria F. Pazyra-Murphy, Samuel M. Cohen, Christian Noti, Toin H. van Kuppevelt, Maria Fuller, Jennifer A. Chan, John J. Hopwood, Peter H. Seeberger, Rosalind A. Segal

J Biol Chem. 2013 Sep 6; 288(36): 26275–26288. Published online 2013 Jul 18. doi: 10.1074/jbc.M112.438937

PMCID:: PMC3764831

Abstract Article PDF–3.9M

Select item 359684916.

Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot

Heather J. Cordell, Ana Töpf, Chrysovalanto Mamasoula, Alex V. Postma, Jamie Bentham, Diana Zelenika, Simon Heath, Gillian Blue, Catherine Cosgrove, Javier Granados Riveron, Rebecca Darlay, Rachel Soemedi, Ian J. Wilson, Kristin L. Ayers, Thahira J. Rahman, Darroch Hall, Barbara J.M. Mulder, Aelko H. Zwinderman, Klaartje van Engelen, J. David Brook, Kerry Setchfield, Frances A. Bu'Lock, Chris Thornborough, John O'Sullivan, A. Graham Stuart, Jonathan Parsons, Shoumo Bhattacharya, David Winlaw, Seema Mital, Marc Gewillig, Jeroen Breckpot, Koen Devriendt, Antoon F.M. Moorman, Anita Rauch, G. Mark Lathrop, Bernard D. Keavney, Judith A. Goodship

Hum Mol Genet. 2013 Apr 1; 22(7): 1473–1481. Published online 2013 Jan 7. doi: 10.1093/hmg/dds552

PMCID:: PMC3596849

Abstract Article PDF–369K

Select item 357841017.

Copy number variation analysis implicates the cell polarity gene glypican 5 as a human spina bifida candidate gene

Alexander G. Bassuk, Lakshmi B. Muthuswamy, Riley Boland, Tiffany L. Smith, Alissa M. Hulstrand, Hope Northrup, Matthew Hakeman, Jason M. Dierdorff, Christina K. Yung, Abby Long, Rachel B. Brouillette, Kit Sing Au, Christina Gurnett, Douglas W. Houston, Robert A. Cornell, J. Robert Manak

Hum Mol Genet. 2013 Mar 15; 22(6): 1097–1111. Published online 2012 Dec 7. doi: 10.1093/hmg/dds515

PMCID:: PMC3578410

Abstract Article PDF–803K

Select item 352258718.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 326170819.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 323867920.

GPC5 rs2352028 variant and risk of lung cancer in never smokers

Maria Teresa Landi, Nilanjan Chatterjee, Neil E. Caporaso, Melissa Rotunno, Demetrius Albanes, Michael Thun, William Wheeler, Albert Rosenberger, Heike Bickeböller, Angela Risch, Yufei Wang, Valerie Gaborieau, Thorgeir Thorgeirsson, Daniel Gudbjartsson, Patrick Sulem, Margaret R. Spitz, H.-Erich Wichmann, Thorunn Rafnar, Kari Stefansson, Richard S. Houlston, Paul Brennan

Lancet Oncol. Author manuscript; available in PMC 2011 Dec 14.

Published in final edited form as: Lancet Oncol. 2010 Aug; 11(8): 714–716. doi: 10.1016/S1470-2045(10)70096-6

PMCID:: PMC3238679

Article PDF–424K

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