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Select item 110148181.

Ginsenoside Rg1 relieves rat intervertebral disc degeneration and inhibits IL-1β-induced nucleus pulposus cell apoptosis and inflammation via NF-κB signaling pathway

Lei Yu, Ying-Jie Hao, Zhi-Nan Ren, Guang-Duo Zhu, Wei-Wei Zhou, Xu Lian, Xue-Jian Wu

In Vitro Cell Dev Biol Anim. 2024; 60(3): 287–299. Published online 2024 Mar 14. doi: 10.1007/s11626-024-00883-6

PMCID:: PMC11014818

Article PDF–10M

Select item 110068512.

Experimental validation and comprehensive analysis of m6A methylation regulators in intervertebral disc degeneration subpopulation classification

Xiaoqian Xu, Lianwei Shen, Yujuan Qu, Danyang Li, Xiaojing Zhao, Hui Wei, Shouwei Yue

Sci Rep. 2024; 14: 8417. Published online 2024 Apr 10. doi: 10.1038/s41598-024-58888-w

PMCID:: PMC11006851

Article PDF–7.7M

Select item 110064603.

Comprehensive analysis of gene expression profiles of annulus fibrosus subtypes and hub genes in intervertebral disc degeneration

Xiaokun Zhao, Jian Zhang, Jiahao Liu, Jinghong Yuan, Tianlong Wu, Xigao Cheng

Aging (Albany NY) 2024 Mar 31; 16(6): 5370–5386. Published online 2024 Mar 13. doi: 10.18632/aging.205653

PMCID:: PMC11006460

Article PDF–8.9M

Select item 109974884.

Altered Metabolism and Inflammation Driven by Post-translational Modifications in Intervertebral Disc Degeneration

Dingchao Zhu, Huaizhen Liang, Zhi Du, Qian Liu, Gaocai Li, Weifeng Zhang, Di Wu, Xingyu Zhou, Yu Song, Cao Yang

Research (Wash D C) 2024; 7: 0350. Published online 2024 Apr 5. doi: 10.34133/research.0350

PMCID:: PMC10997488

Article PDF–4.9M

Select item 109926265.

Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia

Kimheak Sao, Makarand V. Risbud

Neurospine. 2024 Mar; 21(1): 162–178. Published online 2024 Mar 31. doi: 10.14245/ns.2347342.671

PMCID:: PMC10992626

Article PDF–1.1M

Select item 109864076.

The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future Perspectives

Yunxiang Hu, Rui Yang, Sanmao Liu, Zefeng Song, Hong Wang

Drug Des Devel Ther. 2024; 18: 1007–1022. Published online 2024 Mar 29. doi: 10.2147/DDDT.S448807

PMCID:: PMC10986407

Article PDF–5.6M

Select item 109849227.

Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy

Jialiang Lin, Longjie Wang, Yuhao Wu, Qian Xiang, Yongzhao Zhao, Xuanqi Zheng, Shuai Jiang, Zhuoran Sun, Dongwei Fan, Weishi Li

Exp Mol Med. 2024 Mar; 56(3): 747–759. Published online 2024 Mar 27. doi: 10.1038/s12276-024-01196-0

PMCID:: PMC10984922

Article PDF–14M

Select item 109836418.

Role of Galectin-3 in intervertebral disc degeneration: an experimental study

Jianjiang Li, Nianrong Han, Zhenqiang Liu, Akram Osman, Leilei Xu, Jing Song, Yang Xiao, Wei Hu

BMC Musculoskelet Disord. 2024; 25: 249. Published online 2024 Apr 1. doi: 10.1186/s12891-024-07382-5

PMCID:: PMC10983641

Article PDF–2.9M

Select item 109816749.

CircEYA3 aggravates intervertebral disc degeneration through the miR-196a-5p/EBF1 axis and NF-κB signaling

Tianfu Wang, Xiaobing Yan, Dehui Song, Yingxia Li, Zhengwei Li, Dapeng Feng

Commun Biol. 2024; 7: 390. Published online 2024 Mar 30. doi: 10.1038/s42003-024-06055-2

PMCID:: PMC10981674

Article PDF–3.7M

Select item 1098133910.

Sirtuins in intervertebral disc degeneration: current understanding

Jianlin Shen, Yujian Lan, Ziyu Ji, Huan Liu

Mol Med. 2024; 30: 44. Published online 2024 Mar 29. doi: 10.1186/s10020-024-00811-0

PMCID:: PMC10981339

Article PDF–3.3M

Select item 1097722011.

Retracted: Transcriptional Profiling Uncovers Biologically Significant RNAs and Regulatory Networks in Nucleus Pulposus from Intervertebral Disc Degeneration Patients

BioMed Research International

Biomed Res Int. 2024; 2024: 9837415. Published online 2024 Mar 20. doi: 10.1155/2024/9837415

Retracts:: volume 2021 on page 6696335

PMCID:: PMC10977220

Retraction PDF–515K

Select item 1097276812.

Immune-defensive microspheres promote regeneration of the nucleus pulposus by targeted entrapment of the inflammatory cascade during intervertebral disc degeneration

Liang Zhou, Feng Cai, Hongyi Zhu, Yichang Xu, Jincheng Tang, Wei Wang, Ziang Li, Jie Wu, Zhouye Ding, Kun Xi, Liang Chen, Yong Gu

Bioact Mater. 2024 Jul; 37: 132–152. Published online 2024 Mar 20. doi: 10.1016/j.bioactmat.2024.03.020

PMCID:: PMC10972768

Article PDF–23M

Select item 1097187913.

Plant-Derived Senotherapeutics for the Prevention and Treatment of Intervertebral Disc Degeneration and Aging

Eleni Mavrogonatou, Dimitris Kletsas

Metabolites. 2024 Mar; 14(3): 146. Published online 2024 Feb 28. doi: 10.3390/metabo14030146

PMCID:: PMC10971879

Article PDF–1.5M

Select item 1096670514.

Role of Bushen Huoxue Formula and transplanted endothelial progenitor cells play in promoting endplate microcirculation and attenuating intervertebral disc degeneration

Yue Xie, Jianpo Zhang, Shengqi Yang, Weifeng Zhai, Hailiang Zhao, Zhan Shen, Ji Guo, Yongwei Jia

Heliyon. 2024 Mar 30; 10(6): e28095. Published online 2024 Mar 19. doi: 10.1016/j.heliyon.2024.e28095

PMCID:: PMC10966705

Article PDF–10M

Select item 1096422215.

Silencing circATXN1 in Aging Nucleus Pulposus Cell Alleviates Intervertebral Disc Degeneration via Correcting Progerin Mislocalization

Chao Yu, Jing Zhao, Feng Cheng, Jiangjie Chen, Jinyang Chen, Haibin Xu, Kesi Shi, Kaishun Xia, Siwen Ding, Kanbin Wang, Ronghao Wang, Yazhou Chen, Yi Li, Hao Li, Qixin Chen, Xiaohua Yu, Fangwei Shao, Chengzhen Liang, Fangcai Li

Research (Wash D C) 2024; 7: 0336. Published online 2024 Mar 23. doi: 10.34133/research.0336

PMCID:: PMC10964222

Article PDF–6.5M

Select item 1096209316.

Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration

Jing-Yu Ding, Xu Yan, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Rick F. Thorne, Xiao-Ying Liu , Cai-Liang Shen

Eur J Med Res. 2024; 29: 196. Published online 2024 Mar 25. doi: 10.1186/s40001-024-01784-w

PMCID:: PMC10962093

Article PDF–3.8M

Select item 1095468417.

Microenvironment-responsive metal-phenolic network release platform with ROS scavenging, anti-pyroptosis, and ECM regeneration for intervertebral disc degeneration

Hao Zhou, Jinpeng He, Renfeng Liu, Jun Cheng, Yuhao Yuan, Wanpu Mao, Jun Zhou, Honghui He, Qianqi Liu, Wei Tan, Cijun Shuai, Youwen Deng

Bioact Mater. 2024 Jul; 37: 51–71. Published online 2024 Mar 15. doi: 10.1016/j.bioactmat.2024.02.036

PMCID:: PMC10954684

Article PDF–28M

Select item 1095093718.

Increased HIF-2α activity in the nucleus pulposus causes intervertebral disc degeneration in the aging mouse spine

Shira N. Johnston, Maria Tsingas, Rahatul Ain, Ruteja A. Barve, Makarand V. Risbud

Front Cell Dev Biol. 2024; 12: 1360376. Published online 2024 Mar 6. doi: 10.3389/fcell.2024.1360376

PMCID:: PMC10950937

Article PDF–5.9M

Select item 1094395619.

Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment

Yang Liu, Yiming Dou, Xun Sun, Qiang Yang

J Orthop Translat. 2024 Mar; 45: 56–65. Published online 2024 Mar 12. doi: 10.1016/j.jot.2024.02.003

PMCID:: PMC10943956

Article PDF–3.1M

Select item 1094065720.

Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration

Yangyang Zhang, Zhengqi Huang, Weitao Han, Jiajun Wu, Shuangxing Li, Tianyu Qin, Chao Zhang, Ming Shi, Shun Han, Bo Gao, Song Jin, Yin Xiao, Kang Xu, Wei Ye

Commun Biol. 2024; 7: 325. Published online 2024 Mar 14. doi: 10.1038/s42003-024-06000-3