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Select item 110579691.

Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis

Jaehwan Kim, Jongmi Lee, Xuan Li, Hyun Soo Lee, Katherine Kim, Vasuma Chaparala, William Murphy, Wei Zhou, Junyue Cao, Michelle A. Lowes, James G. Krueger

J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Apr 29.

Published in final edited form as: J Allergy Clin Immunol. 2023 Sep; 152(3): 656–666. Published online 2023 Jun 2. doi: 10.1016/j.jaci.2023.05.012

PMCID:: PMC11057969

Abstract Article PDF–2.1M

Select item 109978442.

Clinical and genetic characteristics of three patients with congenital insensitivity to pain with anhidrosis: Case reports and a review of the literature

Jun Hee Cho, Soojin Hwang, Yoon Hae Kwak, Mi‐Sun Yum, Go Hun Seo, June‐Young Koh, Young Seok Ju, Ji‐Hee Yoon, Minji Kang, Hyo‐Sang Do, Soyoung Kim, Gu‐Hwan Kim, Hyunwoo Bae, Beom Hee Lee

Mol Genet Genomic Med. 2024 Apr; 12(4): e2430. Published online 2024 Apr 5. doi: 10.1002/mgg3.2430

PMCID:: PMC10997844

Abstract Article PDF–8.4M

Select item 108368053.

Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa

Kelsey R. van Straalen, Feiyang Ma, Pei-Suen Tsou, Olesya Plazyo, Mehrnaz Gharaee-Kermani, Marta Calbet, Xianying Xing, Mrinal K. Sarkar, Ranjitha Uppala, Paul W. Harms, Rachael Wasikowski, Lina Nahlawi, Mio Nakamura, Milad Eshaq, Cong Wang, Craig Dobry, Jeffrey H. Kozlow, Jill Cherry-Bukowiec, William D. Brodie, Kerstin Wolk, Özge Uluçkan, Megan N. Mattichak, Matteo Pellegrini, Robert L. Modlin, Emanual Maverakis, Robert Sabat, J. Michelle Kahlenberg, Allison C. Billi, Lam C. Tsoi, Johann E. Gudjonsson

J Clin Invest. 2024 Feb 1; 134(3): e169225. Published online 2024 Feb 1. doi: 10.1172/JCI169225

PMCID:: PMC10836805

Abstract Article PDF–5.6M

Select item 108157544.

Unraveling the Epigenetic Tapestry: Decoding the Impact of Epigenetic Modifications in Hidradenitis Suppurativa Pathogenesis

Elena Maria Nardacchione, Paola Maura Tricarico, Ronald Moura, Adamo Pio d’Adamo, Ayshath Thasneem, Muhammad Suleman, Angelo Valerio Marzano, Sergio Crovella, Chiara Moltrasio

Genes (Basel) 2024 Jan; 15(1): 38. Published online 2023 Dec 26. doi: 10.3390/genes15010038

PMCID:: PMC10815754

Abstract Article PDF–4.2M

Select item 107230485.

ALPK1 mutants causing ROSAH syndrome or Spiradenoma are activated by human nucleotide sugars

Tom Snelling, Anton Saalfrank, Nicola T. Wood, Philip Cohen

Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50): e2313148120. Published online 2023 Dec 7. doi: 10.1073/pnas.2313148120

PMCID:: PMC10723048

Abstract Article PDF–429K

Select item 107100696.

Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa

Lin Jin, Yunjia Chen, Suhail Muzaffar, Chao Li, Carlos A. Mier-Aguilar, Jasim Khan, Mahendra P. Kashyap, Shanrun Liu, Ritesh Srivastava, Jessy S. Deshane, Tim M. Townes, Boni E. Elewski, Craig A. Elmets, David K. Crossman, Chander Raman, Mohammad Athar

Proc Natl Acad Sci U S A. 2023 Dec 5; 120(49): e2315096120. Published online 2023 Nov 27. doi: 10.1073/pnas.2315096120

PMCID:: PMC10710069

Abstract Article PDF–5.3M

Select item 107072447.

Transcriptomic Analysis of Hidradenitis Suppurativa: A Unique Molecular Signature with Broad Immune Activation

Hakim Ben Abdallah, Anne Bregnhøj, Lars Iversen, Claus Johansen

Int J Mol Sci. 2023 Dec; 24(23): 17014. Published online 2023 Nov 30. doi: 10.3390/ijms242317014

PMCID:: PMC10707244

Abstract Article PDF–4.1M

Select item 106685738.

Discovering KYNU as a feature gene in hidradenitis suppurativa

Chen Liang, Yue Yu, Qinyu Tang, Liangliang Shen

Int J Immunopathol Pharmacol. 2023 Jan-Dec; 37: 03946320231216317. Published online 2023 Nov 24. doi: 10.1177/03946320231216317

PMCID:: PMC10668573

Abstract Article PDF–8.1M

Select item 106373779.

Genetically predicted levels of circulating cytokines and the risk of six immune skin diseases: a two-sample Mendelian randomization study

Qinghua Luo, Qiurui Cao, Jinyan Guo, Shuangqing Chang, Yunxiang Wu

Front Immunol. 2023; 14: 1240714. Published online 2023 Oct 26. doi: 10.3389/fimmu.2023.1240714

PMCID:: PMC10637377

Abstract Article PDF–6.3M

Select item 1062428410.

Human dermal fibroblast subpopulations and epithelial mesenchymal transition signals in hidradenitis suppurativa tunnels are normalized by spleen tyrosine kinase antagonism in vivo

Akshay Flora, Rebecca Jepsen, Emily K. Kozera, Jane A. Woods, Geoffrey D. Cains, Michael Radzieta, Slade O. Jensen, Matthew Malone, John W. Frew

PLoS One. 2023; 18(11): e0282763. Published online 2023 Nov 3. doi: 10.1371/journal.pone.0282763

PMCID:: PMC10624284

Abstract Article PDF–2.4M

Select item 1061427011.

Clinical and Molecular Characterization of Hidradenitis Suppurativa: A Practical Framework for Novel Therapeutic Targets

Chiara Moltrasio, Paola Maura Tricarico, Ronald Rodrigues Moura, Lucas Brandão, Sergio Crovella, Angelo Valerio Marzano

Dermatology. 2023 Oct; 239(5): 836–839. Published online 2023 Jun 10. doi: 10.1159/000531496

PMCID:: PMC10614270

Abstract Article

Select item 1040387512.

PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1

Jian-Feng Chen, Min Lin, Xu Li, Jian-Bo Lin

Orphanet J Rare Dis. 2023; 18: 205. Published online 2023 Jul 21. doi: 10.1186/s13023-023-02808-0

PMCID:: PMC10403875

Abstract Article PDF–2.3M

Select item 1025300013.

The Essential Role of microRNAs in Inflammatory and Autoimmune Skin Diseases—A Review

Klaudia Dopytalska, Anna Czaplicka, Elżbieta Szymańska, Irena Walecka

Int J Mol Sci. 2023 Jun; 24(11): 9130. Published online 2023 May 23. doi: 10.3390/ijms24119130

PMCID:: PMC10253000

Abstract Article PDF–406K

Select item 1022805914.

Identification of founder and novel mutations that cause congenital insensitivity to pain (CIP) in palestinian patients

Boushra Khaled, Mahmoud Alzahayqa, Ahmad Jaffal, Husam Sallam, Rua’a Thawabta, Mamoun Mansour, Akram Alian, Zaidoun Salah

BMC Med Genomics. 2023; 16: 120. Published online 2023 May 30. doi: 10.1186/s12920-023-01544-5

PMCID:: PMC10228059

Abstract Article PDF–1.3M

Select item 1013909015.

Modulation of Disease-Associated Pathways in Hidradenitis Suppurativa by the Janus Kinase 1 Inhibitor Povorcitinib: Transcriptomic and Proteomic Analyses of Two Phase 2 Studies

Huiqing Liu, Leandro L. Santos, Susan H. Smith

Int J Mol Sci. 2023 Apr; 24(8): 7185. Published online 2023 Apr 13. doi: 10.3390/ijms24087185

PMCID:: PMC10139090

Abstract Article PDF–5.3M

Select item 1008792016.

Adalimumab therapy is associated with increased faecal short chain fatty acids in hidradenitis suppurativa

Artiene Tatian, Sara Bordbar, Samuel Der Sarkissian, Jane A. Woods, Geoffrey D. Cains, Chun Wie Chong, Eliana Mariño, John W. Frew

Exp Dermatol. 2022 Dec; 31(12): 1872–1880. Published online 2022 Aug 30. doi: 10.1111/exd.14665

PMCID:: PMC10087920

Abstract Article PDF–4.8M

Select item 1007906717.

A Hidradenitis Suppurativa molecular disease signature derived from patient samples by high-throughput RNA sequencing and re-analysis of previously reported transcriptomic data sets

Johannes M. Freudenberg, Zhi Liu, Jennifer Singh, Elizabeth Thomas, Christopher Traini, Deepak K. Rajpal, Christopher J. Sayed

PLoS One. 2023; 18(4): e0284047. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0284047

PMCID:: PMC10079067

Abstract Article PDF–1.7M

Select item 1007751018.

Human TrkA^R649W mutation impairs nociception, sweating and cognitive abilities: a mouse model of HSAN IV

Paola Pacifico, Giovanna Testa, Rosy Amodeo, Marco Mainardi, Alexia Tiberi, Domenica Convertino, Juan Carlos Arevalo, Laura Marchetti, Mario Costa, Antonino Cattaneo, Simona Capsoni

Hum Mol Genet. 2023 Apr 15; 32(8): 1380–1400. Published online 2022 Dec 20. doi: 10.1093/hmg/ddac295

PMCID:: PMC10077510

Abstract Article PDF–2.9M

Select item 1006656119.

Rare missense variants in the SH3 domain of PSTPIP1 are associated with hidradenitis suppurativa

David J. Morales-Heil, Li Cao, Cheryl Sweeney, Anna Malara, Frank Brown, Philip Milam, Milan Anadkat, Jessica Kaffenberger, Benjamin Kaffenberger, Peter Nagele, Brian Kirby, Elisha D.O. Roberson

HGG Adv. 2023 Apr 13; 4(2): 100187. Published online 2023 Mar 13. doi: 10.1016/j.xhgg.2023.100187

PMCID:: PMC10066561

Abstract Article PDF–3.1M

Select item 1003892020.

Ophthalmic Manifestations of ROSAH (Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Headache) Syndrome, an Inherited NF κB–Mediated Autoinflammatory Disease with Retinal Dystrophy

Laryssa A. Huryn, Christina Torres Kozycki, Jasmine Y. Serpen, Wadih M. Zein, Ehsan Ullah, Alessandro Iannaccone, Lloyd B. Williams, Lucia Sobrin, Brian P. Brooks, H. Nida Sen, Robert B. Hufnagel, Daniel L. Kastner, Shilpa Kodati

Ophthalmology. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Ophthalmology. 2023 Apr; 130(4): 423–432. Published online 2022 Nov 2. doi: 10.1016/j.ophtha.2022.10.026

PMCID:: PMC10038920

Abstract Article PDF–1.2M

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