PMC Articles for MedGen (Select 1377079) - PMC

Select item 75949151.

Assessment of Predictive Biomarkers of the Response to Pazopanib Based on an Integrative Analysis of High-grade Soft-tissue Sarcomas: Analysis of a Tumor Sample from a Responder and Patients with Other Soft-tissue Sarcomas

Yoshiyuki Suehara, Shinji Kohsaka, Shigeo Yamaguchi, Takuo Hayashi, Taisei Kurihara, Kei Sano, Keita Sasa, Keisuke Akaike, Toshihide Ueno, Shinya Kojima, Masachika Ikegami, Sho Mizuno, Taketo Okubo, Youngji Kim, Kazuo Kaneko, Tsuyoshi Saito, Shunsuke Kato, Hiroyuki Mano

Clin Orthop Relat Res. 2020 Nov; 478(11): 2461–2476. Published online 2020 Jun 10. doi: 10.1097/CORR.0000000000001322

PMCID:: PMC7594915

Abstract Article PDF–1.5M

Select item 53867392.

PLCB4 copy gain and PLCß4 overexpression in primary gastrointestinal stromal tumors: Integrative characterization of a lipid-catabolizing enzyme associated with worse disease-free survival

Chien-Feng Li, Ting-Ting Liu, I-Chieh Chuang, Yen-Yang Chen, Fu-Min Fang, Ti-Chun Chan, Wan-Shan Li, Hsuan-Ying Huang

Oncotarget. 2017 Mar 21; 8(12): 19997–20010. Published online 2017 Feb 13. doi: 10.18632/oncotarget.15306

PMCID:: PMC5386739

Abstract Article PDF–4.7M

Select item 51672423.

In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models

Federica Guffanti, Rosaria Chilà, Ezia Bello, Massimo Zucchetti, Monique Zangarini, Laura Ceriani, Mariella Ferrari, Monica Lupi, Anne Jacquet-Bescond, Mike F. Burbridge, Marie-Jeanne Pierrat, Giovanna Damia

Neoplasia. 2017 Jan; 19(1): 35–42. Published online 2016 Dec 15. doi: 10.1016/j.neo.2016.11.008

PMCID:: PMC5167242

Abstract Article PDF–962K

Select item 42152834.

Next-generation sequencing of adrenocortical carcinoma reveals new routes to targeted therapies

J S Ross, K Wang, J V Rand, L Gay, M J Presta, C E Sheehan, S M Ali, J A Elvin, E Labrecque, C Hiemstra, J Buell, G A Otto, R Yelensky, D Lipson, D Morosini, J Chmielecki, V A Miller, P J Stephens

J Clin Pathol. 2014 Nov; 67(11): 968–973. Published online 2014 Jul 30. doi: 10.1136/jclinpath-2014-202514

PMCID:: PMC4215283

Abstract Article PDF–774K

Select item 39290815.

Differential Tumorigenic Potential and Matriptase Activation between PDGF B versus PDGF D in Prostate Cancer

Abdo J. Najy, Joshua J. Won, Lisa S. Movilla, Hyeong-Reh C. Kim

Mol Cancer Res. Author manuscript; available in PMC 2014 Feb 19.

Published in final edited form as: Mol Cancer Res. 2012 Aug; 10(8): 1087–1097. Published online 2012 Jun 11. doi: 10.1158/1541-7786.MCR-12-0071

PMCID:: PMC3929081

Abstract Article PDF–2.1M

Select item 36436936.

Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-β) is associated with PDGFRB gene copy number gain in sarcomatoid non-small cell lung cancer (NSCLC)

Anne S. Tsao, Wei Wei, Elisabetta Kuhn, Loreto Spencer, Luisa M. Solis, Milind Suraokar, J. Jack Lee, Waun Ki Hong, Ignacio I. Wistuba

Clin Lung Cancer. Author manuscript; available in PMC 2013 May 3.

Published in final edited form as: Clin Lung Cancer. 2011 Nov; 12(6): 369–374. Published online 2011 May 17. doi: 10.1016/j.cllc.2011.02.002

PMCID:: PMC3643693

Article PDF–2.3M

Select item 32620727.

Suppression of G protein-coupled Receptor Kinase 3 expression is a feature of Classical GBM that is required for maximal growth

B. Mark Woerner, Jingqin Luo, Kristin R. Brown, Erin Jackson, Sonika M. Dahiya, Paul Mischel, Jeffrey L. Benovic, David Piwnica-Worms, Joshua B. Rubin

Mol Cancer Res. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Mol Cancer Res. 2012 Jan; 10(1): 156–166. Published online 2011 Nov 15. doi: 10.1158/1541-7786.MCR-11-0411

PMCID:: PMC3262072

Abstract Article PDF–1.3M

Select item 31604888.

Enhanced efficacy of IGF1R inhibition in paediatric glioblastoma by combinatorial targeting of PDGFRα/β

Aleksandra Bielen, Lara Perryman, Gary M. Box, Melanie Valenti, Alexis de Haven Brandon, Vanessa Martins, Alexa Jury, Sergey Popov, Sharon Gowan, Sebastien Jeay, Florence I. Raynaud, Francesco Hofmann, Darren Hargrave, Suzanne A. Eccles, Chris Jones

Mol Cancer Ther. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Mol Cancer Ther. 2011 Aug; 10(8): 1407–1418. Published online 2011 Jun 9. doi: 10.1158/1535-7163.MCT-11-0205

PMCID:: PMC3160488

Abstract Article PDF–5.1M

Select item 28965539.

A DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN PAEDIATRIC HIGH GRADE GLIOMAS

Dorine A Bax, Alan Mackay, Suzanne E Little, Diana Carvalho, Marta Viana-Pereira, Narinder Tamber, Anita E Grigoriadis, Alan Ashworth, Rui M Reis, David W Ellison, Safa Al-Sarraj, Darren Hargrave, Chris Jones

Clin Cancer Res. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Clin Cancer Res. 2010 Jul 1; 16(13): 3368–3377. Published online 2010 Jun 22. doi: 10.1158/1078-0432.CCR-10-0438

PMCID:: PMC2896553

Abstract Article PDF–1.9M

Select item 286437910.

Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis

Philipp Erben, Darko Gosenca, Martin C. Müller, Jelena Reinhard, Joannah Score, Francesco del Valle, Christoph Walz, Jürgen Mix, Georgia Metzgeroth, Thomas Ernst, Claudia Haferlach, Nicholas C.P. Cross, Andreas Hochhaus, Andreas Reiter

Haematologica. 2010 May; 95(5): 738–744. Published online 2010 Jan 27. doi: 10.3324/haematol.2009.016345

PMCID:: PMC2864379

Abstract Article PDF–651K

Select item 189237311.

Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans

Sabine C. Linn, Rob B. West, Jonathan R. Pollack, Shirley Zhu, Tina Hernandez-Boussard, Torsten O. Nielsen, Brian P. Rubin, Rajiv Patel, John R. Goldblum, David Siegmund, David Botstein, Patrick O. Brown, C. Blake Gilks, Matt van de Rijn

Am J Pathol. 2003 Dec; 163(6): 2383–2395. doi: 10.1016/S0002-9440(10)63593-6