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Select item 105925121.

FDA Approval Summary: Futibatinib for Unresectable Advanced or Metastatic, Chemotherapy Refractory Intrahepatic Cholangiocarcinoma with FGFR2 Fusions or Other Rearrangements

Shruti U. Gandhy, Sandra J. Casak, Sirisha L Mushti, Joyce Cheng, Sriram Subramaniam, Hong Zhao, Miao Zhao, Youwei Bi, Guansheng Liu, Jianghong Fan, Oluseyi Adeniyi, Rosane Charlab, Dubravka Kufrin, Matthew D. Thompson, Kristin Jarrell, Doris Auth, Steven J. Lemery, Richard Pazdur, Paul G. Kluetz, Lola A. Fashoyin-Aje

Clin Cancer Res. Author manuscript; available in PMC 2024 Apr 13.

Published in final edited form as: Clin Cancer Res. 2023 Oct 13; 29(20): 4027–4031. doi: 10.1158/1078-0432.CCR-23-1042

PMCID:: PMC10592512

Article PDF–345K

Select item 103793112.

Molecular Biology and Therapeutic Targets of Primitive Tracheal Tumors: Focus on Tumors Derived by Salivary Glands and Squamous Cell Carcinoma

Alessandro Marchioni, Roberto Tonelli, Anna Valeria Samarelli, Gaia Francesca Cappiello, Alessandro Andreani, Luca Tabbì, Francesco Livrieri, Annamaria Bosi, Ottavia Nori, Francesco Mattioli, Giulia Bruzzi, Daniele Marchioni, Enrico Clini

Int J Mol Sci. 2023 Jul; 24(14): 11370. Published online 2023 Jul 12. doi: 10.3390/ijms241411370

PMCID:: PMC10379311

Article PDF–1.3M

Select item 102371103.

Endoscopic ultrasound-guided fine-needle aspiration pancreatic adenocarcinoma samples yield adequate DNA for next-generation sequencing: A cohort analysis

Stefania Bunduc, Bianca Varzaru, Razvan Andrei Iacob, Andrei Sorop, Ioana Manea, Andreea Spiridon, Raluca Chelaru, Adina Emilia Croitoru, Gabriel Becheanu, Mona Dumbrava, Simona Dima, Irinel Popescu, Cristian Gheorghe

World J Gastroenterol. 2023 May 14; 29(18): 2864–2874. Published online 2023 May 14. doi: 10.3748/wjg.v29.i18.2864

PMCID:: PMC10237110

Article PDF–884K

Select item 99919844.

FDA Approval Summary: Pemigatinib for Previously Treated, Unresectable Locally Advanced or Metastatic Cholangiocarcinoma with FGFR2 Fusion or Other Rearrangement

Timil H. Patel, Leigh Marcus, M. Naomi Horiba, Martha Donoghue, Somak Chatterjee, Pallavi S. Mishra-Kalyani, Robert N. Schuck, Yangbing Li, Xinyuan Zhang, Jeanne Fourie Zirkelbach, Rosane Charlab, Jiang Liu, Yuching Yang, Steven J. Lemery, Richard Pazdur, Marc R. Theoret, Lola A. Fashoyin-Aje

Clin Cancer Res. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Clin Cancer Res. 2023 Mar 1; 29(5): 838–842. doi: 10.1158/1078-0432.CCR-22-2036

PMCID:: PMC9991984

Article PDF–81K

Select item 98732495.

Human Metastatic Cholangiocarcinoma Patient-Derived Xenografts and Tumoroids for Preclinical Drug Evaluation

Queralt Serra-Camprubí, Helena Verdaguer, Winona Oliveros, Núria Lupión-Garcia, Alba Llop-Guevara, Cristina Molina, Maria Vila-Casadesús, Anthony Turpin, Cindy Neuzillet, Joan Frigola, Jessica Querol, Mariana Yáñez-Bartolomé, Florian Castet, Carles Fabregat-Franco, Carmen Escudero-Iriarte, Marta Escorihuela, Enrique J. Arenas, Cristina Bernadó-Morales, Noemí Haro, Francis J. Giles, Óscar J. Pozo, Josep M. Miquel, Paolo G. Nuciforo, Ana Vivancos, Marta Melé, Violeta Serra, Joaquín Arribas, Josep Tabernero, Sandra Peiró, Teresa Macarulla, Tian V. Tian

Clin Cancer Res. 2023 Jan 17; 29(2): 432–445. Published online 2022 Nov 14. doi: 10.1158/1078-0432.CCR-22-2551

PMCID:: PMC9873249

Article PDF–7.0M

Select item 98475516.

Response to Capmatinib in a MET Fusion-positive Cholangiocarcinoma

Anthony Turpin, Clotilde Descarpentries, Valérie Grégoire, Olivier Farchi, Alexis B Cortot, Philippe Jamme

Oncologist. 2023 Jan; 28(1): 80–83. Published online 2023 Jan 18. doi: 10.1093/oncolo/oyac194

PMCID:: PMC9847551

Article PDF–5.2M

Select item 92505967.

FDA Approval Summary: Ivosidenib for the treatment of patients with advanced unresectable or metastatic, chemotherapy refractory cholangiocarcinoma with an IDH1 mutation

Sandra J. Casak, Shan Pradhan, Lola A. Fashoyin-Aje, Yi Ren, Yuan-Li Shen, Yuan Xu, Edwin Chiu Yuen Chow, Ye Xiong, Jeanne Fourie Zirklelbach, Jiang Liu, Rosane Charlab, William F. Pierce, Nataliya Fesenko, Julia A. Beaver, Richard Pazdur, Paul G. Kluetz, Steven J. Lemery

Clin Cancer Res. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Clin Cancer Res. 2022 Jul 1; 28(13): 2733–2737. doi: 10.1158/1078-0432.CCR-21-4462

PMCID:: PMC9250596

Article PDF–595K

Select item 91983758.

Role of molecular genetics in the clinical management of cholangiocarcinoma

N. Normanno, E. Martinelli, D. Melisi, C. Pinto, L. Rimassa, D. Santini, A. Scarpa

ESMO Open. 2022 Jun; 7(3): 100505. Published online 2022 Jun 10. doi: 10.1016/j.esmoop.2022.100505

PMCID:: PMC9198375

Article PDF–883K

Select item 88904309.

Clinicopathological features of PD-L1 protein expression, EBV positivity, and MSI status in patients with advanced gastric and esophagogastric junction adenocarcinoma in Japan

Tsutomu Yoshida, Go Ogura, Mikiko Tanabe, Takuo Hayashi, Chiho Ohbayashi, Mizutomo Azuma, Chikara Kunisaki, Yoichi Akazawa, Soji Ozawa, Sohei Matsumoto, Takayoshi Suzuki, Akira Mitoro, Tetsu Fukunaga, Akiko Shimizu, Go Fujimoto, Takashi Yao

Cancer Biol Ther. 2022; 23(1): 191–200. Published online 2022 Feb 27. doi: 10.1080/15384047.2022.2038002

PMCID:: PMC8890430

Article PDF–1.0M

Select item 871302810.

Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma

Thomas Boerner, Esther Drill, Linda M. Pak, Bastien Nguyen, Carlie S. Sigel, Alexandre Doussot, Paul Shin, Debra A. Goldman, Mithat Gonen, Peter J. Allen, Vinod P. Balachandran, Andrea Cercek, James Harding, David B. Solit, Nikolaus Schultz, Ritika Kundra, Henry Walch, Michael I. D’Angelica, Ronald P. DeMatteo, Jeffrey Drebin, Nancy E. Kemeny, T. Peter Kingham, Amber L. Simpson, Jaclyn F. Hechtman, Efsevia Vakiani, Maeve A. Lowery, J.N.M. Ijzermans, S. Buettner, B. Groot Koerkamp, M. Doukas, Rohit Chandwani, William R. Jarnagin

Hepatology. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Hepatology. 2021 Sep; 74(3): 1429–1444. doi: 10.1002/hep.31829

PMCID:: PMC8713028

Article PDF–1.4M

Select item 846155211.

Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial

Andrew X. Zhu, Teresa Macarulla, Milind M. Javle, R. Kate Kelley, Sam J. Lubner, Jorge Adeva, James M. Cleary, Daniel V. T. Catenacci, Mitesh J. Borad, John A. Bridgewater, William P. Harris, Adrian G. Murphy, Do-Youn Oh, Jonathan R. Whisenant, Maeve A. Lowery, Lipika Goyal, Rachna T. Shroff, Anthony B. El-Khoueiry, Christina X. Chamberlain, Elia Aguado-Fraile, Sung Choe, Bin Wu, Hua Liu, Camelia Gliser, Shuchi S. Pandya, Juan W. Valle, Ghassan K. Abou-Alfa

JAMA Oncol. 2021 Nov; 7(11): 1–10. Published online 2021 Sep 23. doi: 10.1001/jamaoncol.2021.3836

PMCID:: PMC8461552

Article

Select item 844842912.

Fibroblast growth factor receptor 2 (FGFR2) fusions in Japanese patients with intrahepatic cholangiocarcinoma

Masanori Tsujie, Tomohisa Iwai, Shoji Kubo, Takashi Ura, Etsuro Hatano, Daisuke Sakai, Yutaka Takeda, Masaki Kaibori, Tomoe Kobayashi, Akio Katanuma, Yu Katayose, Koji Fukase, Naoki Sakurai, Yukiko Ito, Fumiya Sato, Atsuyuki Maeda, Masanori Asada, Chigusa Morizane

Jpn J Clin Oncol. 2021 Jun; 51(6): 911–917. Published online 2021 Apr 3. doi: 10.1093/jjco/hyab029

Correction in:: Jpn J Clin Oncol. 2021 Nov; 51(11): 1694.

PMCID:: PMC8448429

Article PDF–395K

Select item 820941313.

Multicenter phase II study of Cabazitaxel in advanced gastroesophageal cancer: Association of HER2 Expression and M2-like Tumor Associated Macrophages with Patient Outcome

Manish A. Shah, Peter Enzinger, Andrew H Ko, Allyson J Ocean, Philip Agop Philip, Prashant V Thakkar, Kyle Cleveland, Yao Lu, Jeremy Kortmansky, Paul Christos, Chao Zhang, Navjot Kaur, Dina Elmonshed, Giuseppe Galletti, Sandipto Sarkar, Bhavneet Bhinder, Meredith E Pittman, Olga Mikhaylovna Plotnikova, Nikita Kotlov, Felix Frenkel, Aleksander Bagaev, Olivier Elemento, Doron Betel, Paraskevi Giannakakou, Heinz Josef Lenz

Clin Cancer Res. Author manuscript; available in PMC 2021 Jun 17.

Published in final edited form as: Clin Cancer Res. 2020 Sep 15; 26(18): 4756–4766. Published online 2020 Jul 8. doi: 10.1158/1078-0432.CCR-19-3920

PMCID:: PMC8209413

Article PDF–1.3M

Select item 795349414.

Wnt/β-catenin signaling as an emerging potential key pharmacological target in cholangiocarcinoma

Guo-Feng Zhang, Ling Qiu, Shu-Li Yang, Jia-Cheng Wu, Tong-Jun Liu

Biosci Rep. 2020 Mar 27; 40(3): BSR20193353. Published online 2020 Mar 6. doi: 10.1042/BSR20193353

PMCID:: PMC7953494

Article PDF–814K

Select item 792036515.

Baseline serum angiopoietin-2 and VEGF levels predict the deterioration of the liver functional reserve during lenvatinib treatment for hepatocellular carcinoma

Taku Shigesawa, Goki Suda, Megumi Kimura, Osamu Maehara, Yoshimasa Tokuchi, Akinori Kubo, Ren Yamada, Ken Furuya, Masaru Baba, Takashi Kitagataya, Kazuharu Suzuki, Masatsugu Ohara, Naoki Kawagishi, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto

PLoS One. 2021; 16(3): e0247728. Published online 2021 Mar 1. doi: 10.1371/journal.pone.0247728

PMCID:: PMC7920365

Article PDF–1.1M

Select item 788703516.

Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real World Endoscopic Aspiration Samples

Alexander Semaan, Vincent Bernard, Jaewon J. Lee, Justin W. Wong, Jonathan Huang, Daniel B. Swartzlander, Bret M. Stephens, Maria E. Monberg, Brian R. Weston, Manoop S. Bhutani, Kyle Chang, Paul A. Scheet, Anirban Maitra, Yasminka A. Jakubek, Paola A. Guerrero

Clin Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Clin Cancer Res. 2021 Feb 15; 27(4): 1082–1093. Published online 2020 Nov 13. doi: 10.1158/1078-0432.CCR-20-2667

PMCID:: PMC7887035

Article PDF–1.6M

Select item 714069517.

New and Emerging Systemic Therapeutic Options for Advanced Cholangiocarcinoma

Sara Massironi, Lorenzo Pilla, Alessandra Elvevi, Raffaella Longarini, Roberta Elisa Rossi, Paolo Bidoli, Pietro Invernizzi

Cells. 2020 Mar; 9(3): 688. Published online 2020 Mar 11. doi: 10.3390/cells9030688

PMCID:: PMC7140695

Article PDF–3.8M

Select item 615848518.

Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?

Giorgia Marisi, Alessandro Cucchetti, Paola Ulivi, Matteo Canale, Giuseppe Cabibbo, Leonardo Solaini, Francesco G Foschi, Serena De Matteis, Giorgio Ercolani, Martina Valgiusti, Giovanni L Frassineti, Mario Scartozzi, Andrea Casadei Gardini

World J Gastroenterol. 2018 Sep 28; 24(36): 4152–4163. Published online 2018 Sep 28. doi: 10.3748/wjg.v24.i36.4152

PMCID:: PMC6158485

Article PDF–1.0M

Select item 615187619.

CRISPR/Cas9-mediated hypoxia inducible factor-1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma

Quan Liu, Dahua Fan, Dickson Adah, Zhengzhi Wu, Renyan Liu, Qiao-Ting Yan, Yue Zhang, Zhi-Yong Du, Dou Wang, Yan Li, Shi-Yun Bao, Li-Ping Liu

Oncol Rep. 2018 Nov; 40(5): 2547–2557. Published online 2018 Aug 23. doi: 10.3892/or.2018.6667

PMCID:: PMC6151876

Article PDF–1.3M

Select item 612079720.

Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance

Marcia Irene Canto, Jose Alejandro Almario, Richard D. Schulick, Charles J. Yeo, Alison Klein, Amanda Blackford, Eun Ji Shin, Abanti Sanyal, Gayane Yenokyan, Anne Marie Lennon, Ihab R. Kamel, Elliot K. Fishman, Christopher Wolfgang, Matthew Weiss, Ralph H. Hruban, Michael Goggins

Gastroenterology. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Gastroenterology. 2018 Sep; 155(3): 740–751.e2. Published online 2018 May 24. doi: 10.1053/j.gastro.2018.05.035

PMCID:: PMC6120797

Article PDF–541K

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