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Select item 110515151.

Gene Variants of the OAS/RNase L Pathway and Their Association with Severity of Symptoms and Outcome of SARS-CoV-2 Infection

Aurelio Perez-Favila, Sonia Sanchez-Macias, Sergio A. Oropeza De Lara, Idalia Garza-Veloz, Roxana Araujo-Espino, Maria E. Castañeda-Lopez, Alejandro Mauricio-Gonzalez, Sodel Vazquez-Reyes, Perla Velasco-Elizondo, Perla M. Trejo-Ortiz, Fabiana E. Mollinedo Montaño, Claudia Castruita-De la Rosa, Margarita L. Martinez-Fierro

J Pers Med. 2024 Apr; 14(4): 426. Published online 2024 Apr 17. doi: 10.3390/jpm14040426

PMCID:: PMC11051515

Abstract Article PDF–282K

Select item 109753672.

OAS Deep Q-Learning-Based Fast and Smooth Control Method for Traffic Signal Transition in Urban Arterial Tidal Lanes

Luxi Dong, Xiaolan Xie, Jiali Lu, Liangyuan Feng, Lieping Zhang

Sensors (Basel) 2024 Mar; 24(6): 1845. Published online 2024 Mar 13. doi: 10.3390/s24061845

PMCID:: PMC10975367

Abstract Article PDF–13M

Select item 109361863.

Genetic synergy between Acinetobacter baumannii undecaprenyl phosphate biosynthesis and the Mla system impacts cell envelope and antimicrobial resistance

Hannah R. Noel, Sowmya Keerthi, Xiaomei Ren, Jonathan D. Winkelman, Jerry M. Troutman, Lauren D. Palmer

mBio. 2024 Mar; 15(3): e02804-23. Published online 2024 Feb 16. doi: 10.1128/mbio.02804-23

PMCID:: PMC10936186

Abstract Article PDF–2.8M

Select item 109256934.

The Mla system and its role in maintaining outer membrane barrier function in Stenotrophomonas maltophilia

Xavier Coves, Uwe Mamat, Oscar Conchillo-Solé, Pol Huedo, Marc Bravo, Andromeda-Celeste Gómez, Ines Krohn, Wolfgang R. Streit, Ulrich E. Schaible, Isidre Gibert, Xavier Daura, Daniel Yero

Front Cell Infect Microbiol. 2024; 14: 1346565. Published online 2024 Feb 26. doi: 10.3389/fcimb.2024.1346565

PMCID:: PMC10925693

Abstract Article PDF–5.5M

Select item 108350315.

Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L

Stephen A. Goldstein, Nels C. Elde

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2312691121. Published online 2024 Jan 26. doi: 10.1073/pnas.2312691121

PMCID:: PMC10835031

Abstract Article PDF–2.9M

Select item 106654436.

The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking

Kyrie P. Grasekamp, Basile Beaud Benyahia, Najwa Taib, Bianca Audrain, Benjamin Bardiaux, Yannick Rossez, Nadia Izadi-Pruneyre, Maylis Lejeune, Xavier Trivelli, Zina Chouit, Yann Guerardel, Jean-Marc Ghigo, Simonetta Gribaldo, Christophe Beloin

Nat Commun. 2023; 14: 7642. Published online 2023 Nov 23. doi: 10.1038/s41467-023-43411-y

PMCID:: PMC10665443

Abstract Article PDF–2.3M

Select item 105407337.

A dominant-negative avirulence effector of the barley powdery mildew fungus provides mechanistic insight into barley MLA immune receptor activation

Emma E Crean, Merle Bilstein-Schloemer, Takaki Maekawa, Paul Schulze-Lefert, Isabel M L Saur

J Exp Bot. 2023 Sep 29; 74(18): 5854–5869. Published online 2023 Jul 20. doi: 10.1093/jxb/erad285

PMCID:: PMC10540733

Abstract Article PDF–3.5M

Select item 105157508.

Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L

Stephen A. Goldstein, Nels C. Elde

Version 2. bioRxiv. Preprint. 2023 Sep 14. doi: 10.1101/2023.05.12.540623

Published in:: Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2312691121.

PMCID:: PMC10515750

Abstract Article PDF–5.8M

Select item 104744539.

Dynamic players and intricate interactions: An integrated investigation of the Mla lipid transport system

Dixon Ng, Trevor F. Moraes

J Biol Chem. 2023 Sep; 299(9): 105146. Published online 2023 Aug 9. doi: 10.1016/j.jbc.2023.105146

PMCID:: PMC10474453

Abstract Article PDF–764K

Select item 1045100010.

Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

Danyel Lee, Jérémie Le Pen, Ahmad Yatim, Beihua Dong, Yann Aquino, Masato Ogishi, Rémi Pescarmona, Estelle Talouarn, Darawan Rinchai, Peng Zhang, Magali Perret, Zhiyong Liu, Iolanda Jordan, Sefika Elmas Bozdemir, Gulsum Iclal Bayhan, Camille Beaufils, Lucy Bizien, Aurelie Bisiaux, Weite Lei, Milena Hasan, Jie Chen, Christina Gaughan, Abhishek Asthana, Valentina Libri, Joseph M. Luna, Fabrice Jaffré, H.-Heinrich Hoffmann, Eleftherios Michailidis, Marion Moreews, Yoann Seeleuthner, Kaya Bilguvar, Shrikant Mane, Carlos Flores, Yu Zhang, Andrés A. Arias, Rasheed Bailey, Agatha Schlüter, Baptiste Milisavljevic, Benedetta Bigio, Tom Le Voyer, Marie Materna, Adrian Gervais, Marcela Moncada-Velez, Francesca Pala, Tomi Lazarov, Romain Levy, Anna-Lena Neehus, Jérémie Rosain, Jessica Peel, Yi-Hao Chan, Marie-Paule Morin, Rosa Maria Pino-Ramirez, Serkan Belkaya, Lazaro Lorenzo, Jordi Anton, Selket Delafontaine, Julie Toubiana, Fanny Bajolle, Victoria Fumadó, Marta L. DeDiego, Nadhira Fidouh, Flore Rozenberg, Jordi Pérez-Tur, Shuibing Chen, Todd Evans, Frédéric Geissmann, Pierre Lebon, Susan R. Weiss, Damien Bonnet, Xavier Duval, CoV-Contact Cohort, COVID Human Genetic Effort, Qiang Pan-Hammarström, Anna M. Planas, Isabelle Meyts, Filomeen Haerynck, Aurora Pujol, Vanessa Sancho-Shimizu, Clifford L. Dalgard, Jacinta Bustamante, Anne Puel, Stéphanie Boisson-Dupuis, Bertrand Boisson, Tom Maniatis, Qian Zhang, Paul Bastard, Luigi Notarangelo, Vivien Béziat, Rebeca Perez de Diego, Carlos Rodriguez-Gallego, Helen C. Su, Richard P. Lifton, Emmanuelle Jouanguy, Aurélie Cobat, Laia Alsina, Sevgi Keles, Elie Haddad, Laurent Abel, Alexandre Belot, Lluis Quintana-Murci, Charles M. Rice, Robert H. Silverman, Shen-Ying Zhang, Jean-Laurent Casanova

Science. 2023 Feb 10; 379(6632): eabo3627. Published online 2023 Feb 10. doi: 10.1126/science.abo3627

PMCID:: PMC10451000

Abstract Article PDF–5.6M

Select item 1040099811.

Origin of the OAS–RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering

Lingyu Chu, Zhen Gong, Wenqiang Wang, Guan-Zhu Han

Proc Natl Acad Sci U S A. 2023 Aug 1; 120(31): e2304687120. Published online 2023 Jul 24. doi: 10.1073/pnas.2304687120

PMCID:: PMC10400998

Abstract Article PDF–3.2M

Select item 1032098612.

The Skeletal Oncology Research Group Machine Learning Algorithm (SORG-MLA) for predicting prolonged postoperative opioid prescription after total knee arthroplasty: an international validation study using 3,495 patients from a Taiwanese cohort

Cheng-Chen Tsai, Chuan-Ching Huang, Ching-Wei Lin, Paul T. Ogink, Chih-Chi Su, Shin-Fu Chen, Mao-Hsu Yen, Jorrit-Jan Verlaan, Joseph H. Schwab, Chen-Ti Wang, Olivier Q. Groot, Ming-Hsiao Hu, Hongsen Chiang

BMC Musculoskelet Disord. 2023; 24: 553. Published online 2023 Jul 5. doi: 10.1186/s12891-023-06667-5

PMCID:: PMC10320986

Abstract Article PDF–1.1M

Select item 1024862313.

Enhancement of root sulfur metabolic pathway by overexpression of OAS-TL3 to increase total soybean seed protein content

Ye Zhang, Han-zhu Zhang, Abraham Lamboro, Jia-yu Fu, Ye-yao Du, Jing Qu, Pi-wu Wang, Yang Song

Mol Breed. 2023 Jan; 43(1): 4. Published online 2023 Jan 12. doi: 10.1007/s11032-022-01348-y

PMCID:: PMC10248623

Abstract Article PDF–4.2M

Select item 1024506914.

Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning

Mark R. MacRae, Dhenesh Puvanendran, Max A.B. Haase, Nicolas Coudray, Ljuvica Kolich, Cherry Lam, Minkyung Baek, Gira Bhabha, Damian C. Ekiert

J Biol Chem. 2023 Jun; 299(6): 104744. Published online 2023 Apr 25. doi: 10.1016/j.jbc.2023.104744

PMCID:: PMC10245069

Abstract Article PDF–4.8M

Select item 1021250915.

Forward or backward, that is the question: phospholipid trafficking by the Mla system

Javier Abellon-Ruiz

Emerg Top Life Sci. 2023 Mar 31; 7(1): 125–135. Published online 2022 Dec 2. doi: 10.1042/ETLS20220087

PMCID:: PMC10212509

Abstract Article PDF–8.2M

Select item 1019928016.

Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family

Silvia Torices, Timea Teglas, Oandy Naranjo, Nikolai Fattakhov, Kristyna Frydlova, Rosalba Cabrera, Olivia M. Osborne, Enze Sun, Allan Kluttz, Michal Toborek

Mol Neurobiol. 2023; 60(9): 4966–4982. Published online 2023 May 20. doi: 10.1007/s12035-023-03381-0