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Items: 1 to 20 of 43

1.
Expression of oncogenic K-ras and loss of Smad4 cooperate to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells
Shujie Zhao, Yubao Wang, Lin Cao, Michel M. Ouellette, James W. Freeman
Int J Cancer. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Int J Cancer. 2010 Nov 1; 127(9): 2076–2087. doi: 10.1002/ijc.25412
PMCID:
PMC2932752
AbstractArticlePDF–650K
2.
Whole genomes redefine the mutational landscape of pancreatic cancer
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K. Chang, Karin S. Kassahn, Peter Bailey, Amber L. Johns, David Miller, Katia Nones, Kelly Quek, Michael C. J. Quinn, Alan J. Robertson, Muhammad Z. H. Fadlullah, Tim J. C. Bruxner, Angelika N. Christ, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Craig Nourse, Ehsan Nourbakhsh, Shivangi Wani, Peter J Wilson, Emma Markham, Nicole Cloonan, Matthew J. Anderson, J. Lynn Fink, Oliver Holmes, Stephen H. Kazakoff, Conrad Leonard, Felicity Newell, Barsha Poudel, Sarah Song, Darrin Taylor, Nick Waddell, Scott Wood, Qinying Xu, Jianmin Wu, Mark Pinese, Mark J. Cowley, Hong C. Lee, Marc D. Jones, Adnan M. Nagrial, Jeremy Humphris, Lorraine A. Chantrill, Venessa Chin, Angela M. Steinmann, Amanda Mawson, Emily S. Humphrey, Emily K. Colvin, Angela Chou, Christopher J. Scarlett, Andreia V. Pinho, Marc Giry-Laterriere, Ilse Rooman, Jaswinder S. Samra, James G. Kench, Jessica A. Pettitt, Neil D. Merrett, Christopher Toon, Krishna Epari, Nam Q. Nguyen, Andrew Barbour, Nikolajs Zeps, Nigel B. Jamieson, Janet S. Graham, Simone P. Niclou, Rolf Bjerkvig, Robert Grützmann, Daniela Aust, Ralph H. Hruban, Anirban Maitra, Christine A. Iacobuzio-Donahue, Christopher L. Wolfgang, Richard A. Morgan, Rita T. Lawlor, Vincenzo Corbo, Claudio Bassi, Massimo Falconi, Giuseppe Zamboni, Giampaolo Tortora, Margaret A. Tempero, Australian Pancreatic Cancer Genome Initiative, Anthony J. Gill, James R. Eshleman, Christian Pilarsky, Aldo Scarpa, Elizabeth A. Musgrove, John V. Pearson, Andrew V. Biankin, Sean M. Grimmond
Nature. Author manuscript; available in PMC 2015 Aug 3.
Published in final edited form as: Nature. 2015 Feb 26; 518(7540): 495–501. doi: 10.1038/nature14169
PMCID:
PMC4523082
AbstractArticlePDF–6.8M
3.
Identification by array comparative genomic hybridization of a new amplicon on chromosome 17q highly recurrent in BRCA1 mutated triple negative breast cancer
Sébastien Toffoli, Isabelle Bar, Fadi Abdel-Sater, Paul Delrée, Pascale Hilbert, Frédéric Cavallin, Fabrice Moreau, Wim Van Criekinge, Magali Lacroix-Triki, Mario Campone, Anne-Laure Martin, Henri Roché, Jean-Pascal Machiels, Javier Carrasco, Jean-Luc Canon
Breast Cancer Res. 2014; 16: 466. Published online 2014 Nov 22. doi: 10.1186/s13058-014-0466-y
PMCID:
PMC4303204
AbstractArticlePDF–2.3M
4.
Landscape of Genomic Alterations in Cervical Carcinomas
Akinyemi I. Ojesina, Lee Lichtenstein, Samuel S. Freeman, Chandra Sekhar Pedamallu, Ivan Imaz-Rosshandler, Trevor J. Pugh, Andrew D. Cherniack, Lauren Ambrogio, Kristian Cibulskis, Bjørn Bertelsen, Sandra Romero-Cordoba, Victor Treviño, Karla Vazquez-Santillan, Alberto Salido Guadarrama, Alexi A. Wright, Mara W. Rosenberg, Fujiko Duke, Bethany Kaplan, Rui Wang, Elizabeth Nickerson, Heather M. Walline, Michael S. Lawrence, Chip Stewart, Scott L. Carter, Aaron McKenna, Iram P. Rodriguez-Sanchez, Magali Espinosa-Castilla, Kathrine Woie, Line Bjorge, Elisabeth Wik, Mari K. Halle, Erling A. Hoivik, Camilla Krakstad, Nayeli Belem Gabiño, Gabriela Sofia Gómez-Macías, Lezmes D. Valdez-Chapa, María Lourdes Garza-Rodríguez, German Maytorena, Jorge Vazquez, Carlos Rodea, Adrian Cravioto, Maria L. Cortes, Heidi Greulich, Christopher P. Crum, Donna S. Neuberg, Alfredo Hidalgo-Miranda, Claudia Rangel Escareno, Lars A. Akslen, Thomas E. Carey, Olav K. Vintermyr, Stacey B. Gabriel, Hugo A. Barrera-Saldaña, Jorge Melendez-Zajgla, Gad Getz, Helga B. Salvesen, Matthew Meyerson
Nature. Author manuscript; available in PMC 2014 Sep 12.
Published in final edited form as: Nature. 2014 Feb 20; 506(7488): 371–375. Published online 2013 Dec 25. doi: 10.1038/nature12881
PMCID:
PMC4161954
AbstractArticlePDF–369K
5.
DDIT4/REDD1/RTP801 Is a Novel Negative Regulator of Schwann Cell Myelination
Roberta Noseda, Sophie Belin, Françoise Piguet, Ilaria Vaccari, Stefania Scarlino, Paola Brambilla, Filippo Martinelli Boneschi, Maria Laura Feltri, Lawrence Wrabetz, Angelo Quattrini, Elena Feinstein, Richard L. Huganir, Alessandra Bolino
J Neurosci. 2013 Sep 18; 33(38): 15295–15305. doi: 10.1523/JNEUROSCI.2408-13.2013
PMCID:
PMC3988321
AbstractArticlePDF–3.1M
6.
Comprehensive molecular characterization of urothelial bladder carcinoma
The Cancer Genome Atlas Research Network
Nature. 2014; 507(7492): 315–322. Published online 2014 Jan 29. doi: 10.1038/nature12965
PMCID:
PMC3962515
AbstractArticlePDF–1.0M
7.
PUMA and BIM Are Required for Oncogene Inactivation–Induced Apoptosis
Gregory R. Bean, Yogesh Tengarai Ganesan, Yiyu Dong, Shugaku Takeda, Han Liu, Po M. Chan, Yafen Huang, Lewis A. Chodosh, Gerard P. Zambetti, James J.-D. Hsieh, Emily H.-Y. Cheng
Sci Signal. Author manuscript; available in PMC 2013 Sep 26.
Published in final edited form as: Sci Signal. 2013 Mar 26; 6(268): ra20. Published online 2013 Mar 26. doi: 10.1126/scisignal.2003483
PMCID:
PMC3753585
AbstractArticlePDF–2.0M
8.
Microarray analysis of gene expression in vestibular schwannomas reveals SPP1/MET signaling pathway and androgen receptor deregulation
MIGUEL TORRES-MARTIN, LUIS LASSALETTA, JESUS SAN-ROMAN-MONTERO, JOSE M. DE CAMPOS, ALBERTO ISLA, JAVIER GAVILAN, BARBARA MELENDEZ, GIOVANNY R. PINTO, ROMMEL R. BURBANO, JAVIER S. CASTRESANA, JUAN A. REY
Int J Oncol. 2013 Mar; 42(3): 848–862. Published online 2013 Jan 24. doi: 10.3892/ijo.2013.1798
PMCID:
PMC3597452
AbstractArticlePDF–667K
9.
Cyclophosphamide Dose Intensification May Circumvent Anthracycline Resistance of p53 Mutant Breast Cancers
Jacqueline Lehmann-Che, Fabrice André, Christine Desmedt, Chafika Mazouni, Sylvie Giacchetti, Elisabeth Turpin, Marc Espié, Louis-François Plassa, Michel Marty, Philippe Bertheau, Christos Sotiriou, Martine Piccart, W. Fraser Symmans, Lajos Pusztai, Hugues de Thé
Oncologist. 2010 Mar; 15(3): 246–252. Published online 2010 Mar 12. doi: 10.1634/theoncologist.2009-0243
PMCID:
PMC3227956
AbstractArticlePDF–111K
10.
Targeting the function of the HER2 oncogene in human cancer therapeutics
Mark M. Moasser
Oncogene. Author manuscript; available in PMC 2011 Apr 6.
Published in final edited form as: Oncogene. 2007 Oct 11; 26(46): 6577–6592. Published online 2007 May 7. doi: 10.1038/sj.onc.1210478
PMCID:
PMC3071580
AbstractArticlePDF–365K
11.
Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells
Jiazhuo He, Zuzana Nascakova, Peter Leary, Giovanni Papa, Tomas Valenta, Konrad Basler, Anne Müller
Sci Adv. 2023 Nov 17; 9(46): eadh0322. Published online 2023 Nov 15. doi: 10.1126/sciadv.adh0322
PMCID:
PMC10651120
AbstractArticlePDF–1.7M
12.
A Gene-Alteration Profile of Human Lung Cancer Cell Lines
Raquel Blanco, Reika Iwakawa, Moying Tang, Takashi Kohno, Barbara Angulo, Ruben Pio, Luis M. Montuenga, John D. Minna, Jun Yokota, Montse Sanchez-Cespedes
Hum Mutat. Author manuscript; available in PMC 2010 Jul 9.
Published in final edited form as: Hum Mutat. 2009 Aug; 30(8): 1199–1206. doi: 10.1002/humu.21028
PMCID:
PMC2900846
AbstractArticlePDF–1.1M
13.
Unfavorable Prognosis of CRTC1-MAML2 Positive Mucoepidermoid Tumors with CDKN2A Deletions
Sarah L. Anzick, Wei-dong Chen, Yoonsoo Park, Paul Meltzer, Diana Bell, Adel K. El-Naggar, Frederic J. Kaye
Genes Chromosomes Cancer. Author manuscript; available in PMC 2011 Jan 1.
Published in final edited form as: Genes Chromosomes Cancer. 2010 Jan; 49(1): 59–69. doi: 10.1002/gcc.20719
PMCID:
PMC2783528
AbstractArticlePDF–2.6M
14.
Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type
C B J Vos, N T ter Haar, C Rosenberg, J L Peterse, A-M Cleton-Jansen, C J Cornelisse, M J van de Vijver
Br J Cancer. 1999 Dec; 81(8): 1410–1418. doi: 10.1038/sj.bjc.6693372
PMCID:
PMC2362977
SummaryPDF–477K
15.
Tumour cells of extramammary Paget's disease do not show either p53 mutation or allelic loss at several selected loci implicated in other cancers.
M. Takata, N. Hatta, K. Takehara
Br J Cancer. 1997; 76(7): 904–908. doi: 10.1038/bjc.1997.482
PMCID:
PMC2228065
SummaryPage BrowsePDF–1.4M
16.
The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
Xing Chang, Jian Xin Gao, Qi Jiang, Jing Wen, Nick Seifers, Lishan Su, Virginia L. Godfrey, Tao Zuo, Pan Zheng, Yang Liu
J Exp Med. 2005 Oct 17; 202(8): 1141–1151. doi: 10.1084/jem.20050157
PMCID:
PMC2213221
AbstractArticlePDF–1.5M
17.
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.
U M Moll, G Riou, A J Levine
Proc Natl Acad Sci U S A. 1992 Aug 1; 89(15): 7262–7266. doi: 10.1073/pnas.89.15.7262
PMCID:
PMC49686
SummaryPage BrowsePDF–1.7M
18.
Serotonin 2B receptor is required for heart development
Canan G. Nebigil, Doo-Sup Choi, Andrée Dierich, Pierre Hickel, Marianne Le Meur, Nadia Messaddeq, Jean-Marie Launay, Luc Maroteaux
Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17): 9508–9513. doi: 10.1073/pnas.97.17.9508
PMCID:
PMC16895
AbstractArticlePDF–1.1M
19.
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program
Chang-Rung Chen, Yibin Kang, Joan Massagué
Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3): 992–999. doi: 10.1073/pnas.98.3.992
PMCID:
PMC14697
AbstractArticlePDF–2.0M
20.
Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis
Hua Zhao, Elisha Martin, Fatimah Matalkah, Neal Shah, Alexey Ivanov, J. Michael Ruppert, Paul R. Lockman, Yehenew M. Agazie
Oncogene. Author manuscript; available in PMC 2019 May 22.
Published in final edited form as: Oncogene. 2019 Mar; 38(13): 2275–2290. Published online 2018 Nov 22. doi: 10.1038/s41388-018-0574-8
PMCID:
PMC6440805
AbstractArticlePDF–1.0M

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