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Select item 108666591.

Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia–initiating CBFB::MYH11 oncofusion protein

Ryan B. Day, Julia A. Hickman, Ziheng Xu, Casey D.S. Katerndahl, Francesca Ferraro, Sai Mukund Ramakrishnan, Petra Erdmann-Gilmore, Robert W. Sprung, Yiling Mi, R. Reid Townsend, Christopher A. Miller, Timothy J. Ley

J Clin Invest. 2024 Feb 15; 134(4): e176311. Published online 2023 Dec 7. doi: 10.1172/JCI176311

PMCID:: PMC10866659

Article PDF–9.8M

Select item 100480842.

Molecular Heterogeneity of Pediatric AML with Atypical Promyelocytes Accumulation in Children—A Single Center Experience

Aleksandra Borkovskaia, Sofia Bogacheva, Tatiana Konyukhova, Elina Dadakhanova, Marina Gaskova, Olga Soldatkina, Maria Dubrovina, Alexander Popov, Ekaterina Mikhailova, Evgenia Inushkina, Marat Kazanov, Evgeniy Matveev, Galina Novichkova, Michael Maschan, Alexey Maschan, Yulia Olshanskaya, Elena Zerkalenkova

Genes (Basel) 2023 Mar; 14(3): 675. Published online 2023 Mar 8. doi: 10.3390/genes14030675

PMCID:: PMC10048084

Article PDF–2.5M

Select item 98582713.

Acute Promyelocytic Leukemia with Rare Genetic Aberrations: A Report of Three Cases

Guang Liu, Lanting Liu, Daniel Di Bartolo, Katie Y. Li, Xia Li

Genes (Basel) 2023 Jan; 14(1): 46. Published online 2022 Dec 23. doi: 10.3390/genes14010046

PMCID:: PMC9858271

Article PDF–1.4M

Select item 90276374.

ZBTB16-RARα-Positive Atypical Promyelocytic Leukemia: A Case Report

Laura Pardo Gambarte, Aída Franganillo Suárez, Javier Cornago Navascués, Carlos Soto de Ozaeta, Carlos Blas López, Mireia Atance Pasarisas, Rocío Nieves Salgado Sánchez, Cristina Serrano del Castillo, Raquel Mata Serna, Diego Velasco Rodríguez, José Luis López-Lorenzo, Pilar Llamas-Sillero, Laura Solán Blanco

Medicina (Kaunas) 2022 Apr; 58(4): 520. Published online 2022 Apr 6. doi: 10.3390/medicina58040520

PMCID:: PMC9027637

Article PDF–1.0M

Select item 82454945.

Acute promyelocytic leukemia current treatment algorithms

Musa Yilmaz, Hagop Kantarjian, Farhad Ravandi

Blood Cancer J. 2021 Jun; 11(6): 123. Published online 2021 Jun 30. doi: 10.1038/s41408-021-00514-3

PMCID:: PMC8245494

Article PDF–1.8M

Select item 82096186.

Mutational profile of ZBTB16‐RARA‐positive acute myeloid leukemia

Emiliano Fabiani, Laura Cicconi, Anna Maria Nardozza, Antonio Cristiano, Marianna Rossi, Tiziana Ottone, Giulia Falconi, Mariadomenica Divona, Anna Maria Testi, Ombretta Annibali, Roberto Castelli, Vladimir Lazarevic, Eduardo Rego, Pau Montesinos, Jordi Esteve, Adriano Venditti, Matteo Della Porta, William Arcese, Francesco Lo‐Coco, Maria Teresa Voso

Cancer Med. 2021 Jun; 10(12): 3839–3847. Published online 2021 May 27. doi: 10.1002/cam4.3904

PMCID:: PMC8209618

Article PDF–829K

Select item 79765117.

A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia

Yun Tan, Xiaoling Wang, Huan Song, Yi Zhang, Rongsheng Zhang, Shufen Li, Wen Jin, Saijuan Chen, Hai Fang, Zhu Chen, Kankan Wang

Blood. 2021 Mar 18; 137(11): 1503–1516. Prepublished online 2020 Aug 27. doi: 10.1182/blood.2020005698

PMCID:: PMC7976511

Article

Select item 67380728.

A novel NPM1-RARG-NPM1 chimeric fusion in acute myeloid leukaemia resembling acute promyelocytic leukaemia but resistant to all-trans retinoic acid and arsenic trioxide

Xue Chen, Fang Wang, Yang Zhang, Wen Teng, Panxiang Cao, Xiaoli Ma, Mingyue Liu, Yaoyao Tian, Tong Wang, Daijing Nie, Jing Zhang, Hongxing Liu, Wei Wang

Br J Cancer. 2019 May 28; 120(11): 1023–1025. Published online 2019 Apr 18. doi: 10.1038/s41416-019-0456-z

PMCID:: PMC6738072

Article PDF–814K

Select item 67355879.

Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation

Alberto Catanese, Florian Olde Heuvel, Medhanie Mulaw, Maria Demestre, Julia Higelin, Gotthold Barbi, Axel Freischmidt, Jochen H. Weishaupt, Albert C. Ludolph, Francesco Roselli, Tobias M. Boeckers

Autophagy. 2019; 15(10): 1719–1737. Published online 2019 Apr 2. doi: 10.1080/15548627.2019.1589257

PMCID:: PMC6735587

Article PDF–8.2M

Select item 671365910.

Development of Tigecycline Resistance in Carbapenemase-Producing Klebsiella pneumoniae Sequence Type 147 via AcrAB Overproduction Mediated by Replacement of the ramA Promoter

Eun-Jeong Yoon, Yena Oh, Seok Hoon Jeong

Ann Lab Med. 2020 Jan; 40(1): 15–20. Published online 2019 Aug 19. doi: 10.3343/alm.2020.40.1.15

PMCID:: PMC6713659

Article PDF–283K

Select item 645869011.

Bacillus subtilis RarA forms damage-inducible foci that scan the entire cell

Rogelio Hernández-Tamayo, Peter L. Graumann

BMC Res Notes. 2019; 12: 219. Published online 2019 Apr 11. doi: 10.1186/s13104-019-4252-x

PMCID:: PMC6458690

Article PDF–781K

Select item 638653012.

PML recruits TET2 to regulate DNA modification and cell proliferation in response to chemotherapeutic agent

Chengli Song, Lina Wang, Xiaoyan Wu, Kai Wang, Dan Xie, Qi Xiao, Songyu Li, Kui Jiang, Lujian Liao, John R. Yates, III, Jiing-Dwan Lee, Qingkai Yang

Cancer Res. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Cancer Res. 2018 May 15; 78(10): 2475–2489. Published online 2018 May 7. doi: 10.1158/0008-5472.CAN-17-3091

PMCID:: PMC6386530

Article PDF–2.9M

Select item 616984513.

Eprobe mediated RT-qPCR for the detection of leukemia-associated fusion genes

Koji Tsuchiya, Yoko Tabe, Tomohiko Ai, Takahiro Ohkawa, Kengo Usui, Maiko Yuri, Shigeki Misawa, Soji Morishita, Tomoiku Takaku, Atsushi Kakimoto, Haeun Yang, Hiromichi Matsushita, Takeshi Hanami, Yasunari Yamanaka, Atsushi Okuzawa, Takashi Horii, Yoshihide Hayashizaki, Akimichi Ohsaka

PLoS One. 2018; 13(10): e0202429. Published online 2018 Oct 3. doi: 10.1371/journal.pone.0202429

PMCID:: PMC6169845

Article PDF–4.8M

Select item 599892914.

A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion

Christopher A. Miller, Christopher Tricarico, Zachary L. Skidmore, Geoffrey L. Uy, Yi-Shan Lee, Anjum Hassan, Michelle D. O’Laughlin, Heather Schmidt, Ling Tian, Eric J. Duncavage, Malachi Griffith, Obi L. Griffith, John S. Welch, Lukas D. Wartman

Blood Adv. 2018 Jun 12; 2(11): 1295–1299. Published online 2018 Jun 11. doi: 10.1182/bloodadvances.2017014183

PMCID:: PMC5998929

Article PDF–1.1M

Select item 591912915.

Detection of PML/Retinoic Acid Receptor α Gene Rearrangements by Polymerase Chain Reaction Using Genomic DNA in Patients with Acute Promyelocytic Leukemia

Satoshi Tashiro, Kimio Tanaka, Hiroya Asou, Taiichi Kyo, Hiroo Dohy, Katsuyuki Suzuki, Nanao Kamada

Jpn J Cancer Res. 1993 Feb; 84(2): 110–113. doi: 10.1111/j.1349-7006.1993.tb02841.x

PMCID:: PMC5919129

Article PDF–235K

Select item 591388416.

First case of AML with rare chromosome translocations: a case report of twins

Lin Wang, Yanhua Sun, Yanli Sun, Lingbin Meng, Xin Xu

BMC Cancer. 2018; 18: 458. Published online 2018 Apr 23. doi: 10.1186/s12885-018-4396-4

PMCID:: PMC5913884

Article PDF–459K

Select item 586143617.

Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences

Lorena Infante Lara, Sabine Fenner, Steven Ratcliffe, Albert Isidro-Llobet, Michael Hann, Ben Bax, Neil Osheroff

Nucleic Acids Res. 2018 Mar 16; 46(5): 2218–2233. Published online 2018 Feb 13. doi: 10.1093/nar/gky072

PMCID:: PMC5861436

Article PDF–11M

Select item 584319118.

Identification of a cryptic IRF2BP2-RARA fusion in acute promyelocytic leukemia

C. Cameron Yin, Nitin Jain, Meenakshi Mehrotra, Jianhua Zhang, Alexei Protopopov, Zhuang Zuo, Naveen Pemmaraju, Courtney DiNardo, Cheryl Hirsch-Ginsberg, Sa A. Wang, L. Jeffrey Medeiros, Lynda Chin, Keyur P. Patel, Farhad Ravandi, Andrew Futreal, Carlos E. Bueso-Ramos

J Natl Compr Canc Netw. Author manuscript; available in PMC 2018 Mar 8.

Published in final edited form as: J Natl Compr Canc Netw. 2015 Jan; 13(1): 19–22. doi: 10.6004/jnccn.2015.0005

PMCID:: PMC5843191

Article PDF–996K

Select item 563688019.

The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells

Anna M. Schläfli, Pauline Isakson, E. Garattini, Anne Simonsen, Mario P. Tschan

Sci Rep. 2017; 7: 12980. Published online 2017 Oct 11. doi: 10.1038/s41598-017-12734-4

PMCID:: PMC5636880

Article PDF–1.7M

Select item 556602720.

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells

Giulia Daniele, Giorgia Simonetti, Caterina Fusilli, Ilaria Iacobucci, Angelo Lonoce, Antonio Palazzo, Mariana Lomiento, Fabiana Mammoli, Renè Massimiliano Marsano, Elena Marasco, Vilma Mantovani, Hilmar Quentmeier, Hans G Drexler, Jie Ding, Orazio Palumbo, Massimo Carella, Niroshan Nadarajah, Margherita Perricone, Emanuela Ottaviani, Carmen Baldazzi, Nicoletta Testoni, Cristina Papayannidis, Sergio Ferrari, Tommaso Mazza, Giovanni Martinelli, Clelia Tiziana Storlazzi

Haematologica. 2017 Jul; 102(7): 1204–1214. Prepublished online 2017 Apr 14. doi: 10.3324/haematol.2016.163022

PMCID:: PMC5566027

Article PDF–1.4M

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