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Items: 1 to 20 of 154

1.
PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3
Jorge A. Benitez, Jianhui Ma, Matteo D’Antonio, Antonia Boyer, Maria Fernanda Camargo, Ciro Zanca, Stephen Kelly, Alireza Khodadadi-Jamayran, Nathan M. Jameson, Michael Andersen, Hrvoje Miletic, Shahram Saberi, Kelly A. Frazer, Webster K. Cavenee, Frank B. Furnari
Nat Commun. 2017; 8: 15223. Published online 2017 May 12. doi: 10.1038/ncomms15223
Correction in:
Nat Commun. 2018; 9: 16217.
PMCID:
PMC5437297
AbstractArticlePDF–3.2M
2.
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma
Deguan Lv, Yanxin Li, Weiwei Zhang, Angel A. Alvarez, Lina Song, Jianming Tang, Wei-Qiang Gao, Bo Hu, Shi-Yuan Cheng, Haizhong Feng
Nat Commun. 2017; 8: 1454. Published online 2017 Nov 13. doi: 10.1038/s41467-017-01731-w
PMCID:
PMC5682287
AbstractArticlePDF–2.5M
3.
Brainstem Low-Grade Gliomas in Children—Excellent Outcomes With Multimodality Therapy
Santhosh A. Upadhyaya, Carl Koschmann, Karin Muraszko, Sriram Venneti, Hugh J. Garton, Daniel A. Hamstra, Cormac O. Maher, Bryan L. Betz, Noah A. Brown, Daniel Wahl, Helmut C. Weigelin, Kathleen E. DuRoss, Annette S. Leonard, Patricia L. Robertson
J Child Neurol. Author manuscript; available in PMC 2018 Feb 1.
Published in final edited form as: J Child Neurol. 2017 Feb; 32(2): 194–203. Published online 2016 Nov 3. doi: 10.1177/0883073816675547
PMCID:
PMC5582383
AbstractArticlePDF–234K
4.
Diffuse intrinsic pontine gliomas—current management and new biologic insights. Is there a glimmer of hope?
Kenneth J. Cohen, Nada Jabado, Jacques Grill
Neuro Oncol. 2017 Aug; 19(8): 1025–1034. Published online 2017 Mar 24. doi: 10.1093/neuonc/nox021
PMCID:
PMC5570259
AbstractArticlePDF–1.4M
5.
The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas
Jane L. Anderson, Ranjithmenon Muraleedharan, Nicole Oatman, Amanda Klotter, Satarupa Sengupta, Ronald R. Waclaw, Jianqiang Wu, Rachid Drissi, Lili Miles, Eric H. Raabe, Matthew L. Weirauch, Maryam Fouladi, Lionel M. Chow, Lindsey Hoffman, Mariko DeWire, Biplab Dasgupta
Neuro Oncol. 2017 Aug; 19(8): 1068–1078. Published online 2017 Feb 23. doi: 10.1093/neuonc/now299
PMCID:
PMC5570182
AbstractArticlePDF–118M
6.
The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation
Anne C Solga, Joseph A Toonen, Yuan Pan, Patrick J Cimino, Yu Ma, Guillaume A Castillon, Scott M Gianino, Mark H Ellisman, Da Yong Lee, David H Gutmann
Oncotarget. 2017 Jul 18; 8(29): 47206–47215. Published online 2017 May 3. doi: 10.18632/oncotarget.17589
PMCID:
PMC5564557
AbstractArticlePDF–4.1M
7.
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells
D Maciaczyk, D Picard, L Zhao, K Koch, D Herrera-Rios, G Li, V Marquardt, D Pauck, T Hoerbelt, W Zhang, D M Ouwens, M Remke, T Jiang, H J Steiger, J Maciaczyk, U D Kahlert
Br J Cancer. 2017 Jun 27; 117(1): 102–112. Published online 2017 Jun 1. doi: 10.1038/bjc.2017.157
PMCID:
PMC5520214
AbstractArticlePDF–2.4M
8.
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Andrew S. Venteicher, Itay Tirosh, Christine Hebert, Keren Yizhak, Cyril Neftel, Mariella G. Filbin, Volker Hovestadt, Leah E. Escalante, McKenzie L. Shaw, Christopher Rodman, Shawn M. Gillespie, Danielle Dionne, Christina C. Luo, Hiranmayi Ravichandran, Ravindra Mylvaganam, Christopher Mount, Maristela L. Onozato, Brian V. Nahed, Hiroaki Wakimoto, William T. Curry, A. John Iafrate, Miguel N. Rivera, Matthew P. Frosch, Todd R. Golub, Priscilla K. Brastianos, Gad Getz, Anoop P. Patel, Michelle Monje, Daniel P. Cahill, Orit Rozenblatt-Rosen, David N. Louis, Bradley E. Bernstein, Aviv Regev, Mario L. Suvà
Science. Author manuscript; available in PMC 2018 Mar 31.
Published in final edited form as: Science. 2017 Mar 31; 355(6332): eaai8478. doi: 10.1126/science.aai8478
PMCID:
PMC5519096
AbstractArticlePDF–1.2M
9.
Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells
Yi-Peng Han, Atsushi Enomoto, Yukihiro Shiraki, Shen-Qi Wang, Xiaoze Wang, Shinya Toyokuni, Naoya Asai, Kaori Ushida, Hosne Ara, Fumiharu Ohka, Toshihiko Wakabayashi, Jie Ma, Atsushi Natsume, Masahide Takahashi
Neuro Oncol. 2017 May; 19(5): 636–647. Published online 2016 Dec 8. doi: 10.1093/neuonc/now237
PMCID:
PMC5464440
AbstractArticlePDF–17M
10.
Pediatric low-grade gliomas: implications of the biologic era
Roger J. Packer, Stephan Pfister, Eric Bouffet, Robert Avery, Pratiti Bandopadhayay, Miriam Bornhorst, Daniel C. Bowers, David Ellison, Jason Fangusaro, Nicholas Foreman, Maryam Fouladi, Amar Gajjar, Daphne Haas-Kogan, Cynthia Hawkins, Cheng-Ying Ho, Eugene Hwang, Nada Jabado, Lindsay B. Kilburn, Alvaro Lassaletta, Keith L. Ligon, Maura Massimino, Schouten-van Meeteren, Sabine Mueller, Theo Nicolaides, Giorgio Perilongo, Uri Tabori, Gilbert Vezina, Katherine Warren, Olaf Witt, Yuan Zhu, David T. Jones, Mark Kieran
Neuro Oncol. 2017 Jun; 19(6): 750–761. Published online 2016 Sep 28. doi: 10.1093/neuonc/now209
PMCID:
PMC5464436
AbstractArticlePDF–192K
11.
Low-grade astrocytoma mutations in IDH1, P53 and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2
Aram S. Modrek, Danielle Golub, Themasap Khan, Devin Bready, Jod Prado, Christopher Bowman, Jingjing Deng, Guoan Zhang, Pedro P. Rocha, Ramya Raviram, Charalampos Lazaris, James M. Stafford, Gary LeRoy, Michael Kader, Joravar Dhaliwal, N. Sumru Bayin, Joshua D. Frenster, Jonathan Serrano, Luis Chiriboga, Rabaa Baitalmal, Gouri Nanjangud, Andrew S. Chi, John G. Golfinos, Jing Wang, Matthias A. Karajannis, Richard A. Bonneau, Danny Reinberg, Aristotelis Tsirigos, David Zagzag, Matija Snuderl, Jane A. Skok, Thomas A. Neubert, Dimitris G. Placantonakis
Cell Rep. Author manuscript; available in PMC 2017 Nov 15.
Published in final edited form as: Cell Rep. 2017 Oct 31; 21(5): 1267–1280. doi: 10.1016/j.celrep.2017.10.009
PMCID:
PMC5687844
AbstractArticlePDF–1.4M
12.
Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma
Patricia C. Sanchez-Diaz, Judy C. Chang, Emily S. Moses, Tu Dao, Yidong Chen, Jaclyn Y. Hung
PLoS One. 2017; 12(5): e0176879. Published online 2017 May 4. doi: 10.1371/journal.pone.0176879
PMCID:
PMC5417601
AbstractArticlePDF–1.8M
13.
Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells
Katharina Koch, Rudolf Hartmann, Friederike Schröter, Abigail Kora Suwala, Donata Maciaczyk, Andrea Caroline Krüger, Dieter Willbold, Ulf Dietrich Kahlert, Jaroslaw Maciaczyk
Oncotarget. 2016 Nov 8; 7(45): 73414–73431. Published online 2016 Sep 29. doi: 10.18632/oncotarget.12337
PMCID:
PMC5341988
AbstractArticlePDF–11M
14.
Catenin delta-1 (CTNND1) phosphorylation controls the mesenchymal to epithelial transition in astrocytic tumors
Jin Yang, Alexander G. Bassuk, Juliane Merl-Pham, Chun-Wei Hsu, Diana F. Colgan, Xiaorong Li, Kit Sing Au, Lijuan Zhang, Scott Smemo, Sally Justus, Yasunori Nagahama, Andrew J. Grossbach, Matthew A. Howard, III, Hiroto Kawasaki, Neil A. Feldstein, William B. Dobyns, Hope Northrup, Stefanie M. Hauck, Marius Ueffing, Vinit B. Mahajan, Stephen H. Tsang
Hum Mol Genet. 2016 Oct 1; 25(19): 4201–4210. Published online 2016 Aug 11. doi: 10.1093/hmg/ddw253
PMCID:
PMC5291196
AbstractArticlePDF–1.1M
15.
MicroRNA profiling of low grade glial and glioneuronal tumors shows an independent role for cluster 14q32.31 member miR-487b
Heather Marion Ames, Ming Yuan, Maria Adelita Vizcaíno, Wayne Yu, Fausto J. Rodriguez
Mod Pathol. Author manuscript; available in PMC 2017 Apr 14.
Published in final edited form as: Mod Pathol. 2017 Feb; 30(2): 204–216. Published online 2016 Oct 14. doi: 10.1038/modpathol.2016.177
PMCID:
PMC5288128
AbstractArticlePDF–1.8M
16.
Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy
Guifa Xi, Yuping Derek Li, Gordan Grahovac, Veena Rajaram, Nitin Wadhwani, Tatiana Pundy, Barbara Mania-Farnell, Charles David James, Tadanori Tomita
Mol Cancer. 2017; 16: 21. Published online 2017 Jan 31. doi: 10.1186/s12943-017-0593-z
PMCID:
PMC5282778
AbstractArticlePDF–3.8M
17.
The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma
Harpreet Kaur, Sabeen Zulfiqar Ali, Lauren Huey, Marianne Hütt-Cabezas, Isabella Taylor, Xing-gang Mao, Melanie Weingart, Qian Chu, Fausto J. Rodriguez, Charles G. Eberhart, Eric H. Raabe
Cancer Lett. Author manuscript; available in PMC 2017 Jul 10.
Published in final edited form as: Cancer Lett. 2016 Jul 10; 377(1): 55–64. Published online 2016 Apr 18. doi: 10.1016/j.canlet.2016.04.020
PMCID:
PMC5091648
AbstractArticlePDF–786K
18.
MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma
Jonathan B. Bell, Frank Eckerdt, Kristen Alley, Lisa P. Magnusson, Hridi Hussain, Yingtao Bi, Ahmet Dirim Arslan, Jessica Clymer, Angel A. Alvarez, Stewart Goldman, Shi-Yuan Cheng, Ichiro Nakano, Craig Horbinski, Ramana V. Davuluri, C. David James, Leonidas C. Platanias
Mol Cancer Res. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Mol Cancer Res. 2016 Oct; 14(10): 984–993. Published online 2016 Jun 30. doi: 10.1158/1541-7786.MCR-16-0172
PMCID:
PMC5082426
AbstractArticlePDF–2.0M
19.
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas
Hideyuki Arita, Kai Yamasaki, Yuko Matsushita, Taishi Nakamura, Asanao Shimokawa, Hirokazu Takami, Shota Tanaka, Akitake Mukasa, Mitsuaki Shirahata, Saki Shimizu, Kaori Suzuki, Kuniaki Saito, Keiichi Kobayashi, Fumi Higuchi, Takeo Uzuka, Ryohei Otani, Kaoru Tamura, Kazutaka Sumita, Makoto Ohno, Yasuji Miyakita, Naoki Kagawa, Naoya Hashimoto, Ryusuke Hatae, Koji Yoshimoto, Naoki Shinojima, Hideo Nakamura, Yonehiro Kanemura, Yoshiko Okita, Manabu Kinoshita, Kenichi Ishibashi, Tomoko Shofuda, Yoshinori Kodama, Kanji Mori, Yusuke Tomogane, Junya Fukai, Koji Fujita, Yuzo Terakawa, Naohiro Tsuyuguchi, Shusuke Moriuchi, Masahiro Nonaka, Hiroyoshi Suzuki, Makoto Shibuya, Taketoshi Maehara, Nobuhito Saito, Motoo Nagane, Nobutaka Kawahara, Keisuke Ueki, Toshiki Yoshimine, Etsuo Miyaoka, Ryo Nishikawa, Takashi Komori, Yoshitaka Narita, Koichi Ichimura
Acta Neuropathol Commun. 2016; 4: 79. Published online 2016 Aug 8. doi: 10.1186/s40478-016-0351-2
PMCID:
PMC4977715
AbstractArticlePDF–1.0M
20.
Tectal glioma as a distinct diagnostic entity: a comprehensive clinical, imaging, histologic and molecular analysis
Anthony P. Y. Liu, Julie H. Harreld, Lisa M. Jacola, Madelyn Gero, Sahaja Acharya, Yahya Ghazwani, Shengjie Wu, Xiaoyu Li, Paul Klimo, Jr, Amar Gajjar, Jason Chiang, Ibrahim Qaddoumi
Acta Neuropathol Commun. 2018; 6: 101. Published online 2018 Sep 25. doi: 10.1186/s40478-018-0602-5
PMCID:
PMC6154813
AbstractArticlePDF–2.3M

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