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Items: 1 to 20 of 500

1.
The Transcriptomic Landscape of Pediatric Astrocytoma
Abrahan Hernández-Hernández, Tayde López-Santaella, Aranxa Torres-Caballero, Amarantha Serrato, Ulises Torres-Flores, Diego Montesinos-Valencia, Fernando Chico-Ponce de León, Vicente González-Carranza, Samuel Torres-García, Rosa Rebollar-Vega, Inti Alberto De la Rosa-Velázquez, Rosario Ortiz, Monserrat Pérez-Ramírez, Normand García-Hernández, Antonio García-Méndez, Francisco Arenas-Huertero
Int J Mol Sci. 2022 Oct; 23(20): 12696. Published online 2022 Oct 21. doi: 10.3390/ijms232012696
PMCID:
PMC9604090
AbstractArticlePDF–3.2M
2.
Long-term health and social function in adult survivors of pediatric astrocytoma: A report from the Childhood Cancer Survivor Study
Karen E. Effinger, Kayla Stratton, Paul Graham Fisher, Kirsten K. Ness, Kevin R. Krull, Kevin C. Oeffinger, Gregory T. Armstrong, Leslie L. Robison, Melissa M. Hudson, Wendy M. Leisenring, Paul C. Nathan
Eur J Cancer. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Eur J Cancer. 2019 Jan; 106: 171–180. Published online 2018 Dec 5. doi: 10.1016/j.ejca.2018.10.016
PMCID:
PMC6647033
AbstractArticlePDF–577K
3.
Histone Mark Profiling in Pediatric Astrocytomas Reveals Prognostic Significance of H3K9 Trimethylation and Histone Methyltransferase SUV39H1
Alexia Klonou, Penelope Korkolopoulou, Antonios N. Gargalionis, Dimitrios S. Kanakoglou, Hector Katifelis, Maria Gazouli, Sarantis Chlamydas, Andreas Mitsios, Theodosis Kalamatianos, George Stranjalis, Marios S. Themistocleous, Kostas A. Papavassiliou, Spyros Sgouros, Athanasios G. Papavassiliou, Christina Piperi
Neurotherapeutics. 2021 Jul; 18(3): 2073–2090. Published online 2021 Jul 22. doi: 10.1007/s13311-021-01090-x
PMCID:
PMC8609021
AbstractArticlePDF–2.9M
4.
Germline cancer predisposition variants and pediatric glioma: a population-based study in California
Ivo S Muskens, Adam J de Smith, Chenan Zhang, Helen M Hansen, Libby Morimoto, Catherine Metayer, Xiaomei Ma, Kyle M Walsh, Joseph L Wiemels
Neuro Oncol. 2020 Jun; 22(6): 864–874. Published online 2020 Jan 23. doi: 10.1093/neuonc/noaa014
PMCID:
PMC7283023
AbstractArticlePDF–3.4M
5.
Targeting energy metabolism in brain cancer: review and hypothesis
Thomas N Seyfried, Purna Mukherjee
Nutr Metab (Lond) 2005; 2: 30. Published online 2005 Oct 21. doi: 10.1186/1743-7075-2-30
PMCID:
PMC1276814
AbstractArticlePDF–387K
6.
Bcl‐2/Bcl‐xL inhibition predominantly synergistically enhances the anti‐neoplastic activity of a low‐dose CUSP9 repurposed drug regime against glioblastoma
Marc‐Eric Halatsch, Richard Eric Kast, Annika Dwucet, Michal Hlavac, Tim Heiland, Mike‐Andrew Westhoff, Klaus‐Michael Debatin, Christian Rainer Wirtz, Markus David Siegelin, Georg Karpel‐Massler
Br J Pharmacol. 2019 Sep; 176(18): 3681–3694. Published online 2019 Jul 30. doi: 10.1111/bph.14773
PMCID:
PMC6715605
AbstractArticlePDF–2.6M
7.
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
Youzhou Sang, Yanxin Li, Yingwen Zhang, Angel A. Alvarez, Bo Yu, Weiwei Zhang, Bo Hu, Shi-Yuan Cheng, Haizhong Feng
Nat Commun. 2019; 10: 4013. Published online 2019 Sep 5. doi: 10.1038/s41467-019-12001-2
PMCID:
PMC6728346
AbstractArticlePDF–5.3M
8.
Integrative analysis of DNA methylation and gene expression to identify key epigenetic genes in glioblastoma
Danyun Jia, Wei Lin, Hongli Tang, Yifan Cheng, Kaiwei Xu, Yanshu He, Wujun Geng, Qinxue Dai
Aging (Albany NY) 2019 Aug 15; 11(15): 5579–5592. Published online 2019 Aug 8. doi: 10.18632/aging.102139
PMCID:
PMC6710056
AbstractArticlePDF–5.1M
9.
Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes
Yifan Xue, Gregory Cooper, Chunhui Cai, Songjian Lu, Baoli Hu, Xiaojun Ma, Xinghua Lu
Sci Rep. 2019; 9: 13225. Published online 2019 Sep 13. doi: 10.1038/s41598-019-48318-7
PMCID:
PMC6744493
AbstractArticlePDF–4.5M
10.
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
Siti Farah Bte Fadhlullah, Nurashikin Bte Abdul Halim, Jacqueline Y. T. Yeo, Rachel L. Y. Ho, Phoebe Um, Beng Ti Ang, Carol Tang, Wai H. Ng, David M. Virshup, Ivy A. W. Ho
Oncogene. 2019; 38(27): 5367–5380. Published online 2019 Apr 9. doi: 10.1038/s41388-019-0809-3
PMCID:
PMC6755990
AbstractArticlePDF–3.2M
11.
Three de novo DDX3X variants associated with distinctive brain developmental abnormalities and brain tumor in intellectually disabled females
Marcello Scala, Annalaura Torella, Mariasavina Severino, Giovanni Morana, Raffaele Castello, Andrea Accogli, Antonio Verrico, Maria Stella Vari, Gerarda Cappuccio, Michele Pinelli, Giuseppina Vitiello, Gaetano Terrone, Alessandra D’Amico, TUDP consortium, Vincenzo Nigro, Valeria Capra
Eur J Hum Genet. 2019 Aug; 27(8): 1254–1259. Published online 2019 Apr 1. doi: 10.1038/s41431-019-0392-7
PMCID:
PMC6777618
AbstractArticlePDF–732K
12.
Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling
Ryan C. Gimple, Reilly L. Kidwell, Leo J.Y. Kim, Tengqian Sun, Anthony D. Gromovsky, Qiulian Wu, Megan Wolf, Deguan Lv, Shruti Bhargava, Li Jiang, Briana C. Prager, Xiuxing Wang, Qing Ye, Zhe Zhu, Guoxin Zhang, Zhen Dong, Linjie Zhao, Derrick Lee, Junfeng Bi, Andrew E. Sloan, Paul S. Mischel, J. Mark Brown, Hu Cang, Tao Huan, Stephen C. Mack, Qi Xie, Jeremy N. Rich
Cancer Discov. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Cancer Discov. 2019 Sep; 9(9): 1248–1267. Published online 2019 Jun 14. doi: 10.1158/2159-8290.CD-19-0061
PMCID:
PMC6785242
AbstractArticlePDF–4.0M
13.
Prolonged survival in a patient with a cervical spine H3K27M-mutant diffuse midline glioma
Kelsey Peters, Drew Pratt, Carl Koschmann, Denise Leung
BMJ Case Rep. 2019; 12(10): e231424. Published online 2019 Oct 17. doi: 10.1136/bcr-2019-231424
PMCID:
PMC6803116
AbstractArticlePDF–1.0M
14.
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma
Nina Struve, Zev A. Binder, Lucy F. Stead, Tim Brend, Stephen J. Bagley, Claire Faulkner, Leonie Ott, Justus Müller-Goebel, Anna-Sophie Weik, Konstantin Hoffer, Leonie Krug, Thorsten Rieckmann, Lara Bußmann, Marvin Henze, Jennifer J. D. Morrissette, Kathreena M. Kurian, Ulrich Schüller, Cordula Petersen, Kai Rothkamm, Donald M. O´ Rourke, Susan C. Short, Malte Kriegs
Oncogene. 2020; 39(15): 3041–3055. Published online 2020 Feb 17. doi: 10.1038/s41388-020-1208-5
PMCID:
PMC7142016
AbstractArticlePDF–3.4M
15.
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Junfei Zhao, Andrew X. Chen, Robyn D. Gartrell, Andrew M. Silverman, Luis Aparicio, Tim Chu, Darius Bordbar, David Shan, Jorge Samanamud, Aayushi Mahajan, Ioan Filip, Rose Orenbuch, Morgan Goetz, Jonathan T. Yamaguchi, Michael Cloney, Craig Horbinski, Rimas V. Lukas, Jeffrey Raizer, Ali Rae, I, Jinzhou Yuan, Peter Canoll, Jeffrey N. Bruce, Yvonne M. Saenger, Peter Sims, Fabio M. Iwamoto, Adam M. Sonabend, Raul Rabadan
Nat Med. Author manuscript; available in PMC 2019 Oct 23.
Published in final edited form as: Nat Med. 2019 Mar; 25(3): 462–469. Published online 2019 Feb 11. doi: 10.1038/s41591-019-0349-y
PMCID:
PMC6810613
AbstractArticlePDF–1.4M
16.
Lynch syndrome–associated ultra-hypermutated pediatric glioblastoma mimicking a constitutional mismatch repair deficiency syndrome
Chen Yang, Frances Austin, Hope Richard, Michael Idowu, Vernell Williamson, Fernanda Sabato, Andrea Ferreira-Gonzalez, Scott A. Turner
Cold Spring Harb Mol Case Stud. 2019 Oct; 5(5): a003863. doi: 10.1101/mcs.a003863
PMCID:
PMC6824252
AbstractArticlePDF–8.1M
17.
PD-L1/PD-1 Axis in Glioblastoma Multiforme
Jakub Litak, Marek Mazurek, Cezary Grochowski, Piotr Kamieniak, Jacek Roliński
Int J Mol Sci. 2019 Nov; 20(21): 5347. Published online 2019 Oct 28. doi: 10.3390/ijms20215347
PMCID:
PMC6862444
AbstractArticlePDF–2.3M
18.
Imatinib Revives the Therapeutic Potential of Metformin on Ewing Sarcoma by Attenuating Tumor Hypoxic Response and Inhibiting Convergent Signaling Pathways
Xiang Nan, Jiang Wang, Hao Cheng, Zheng Yin, Jianting Sheng, Bensheng Qiu, Ching C. Lau, Jason T Yustein, Hong Zhao, Stephen T.C. Wong
Cancer Lett. Author manuscript; available in PMC 2021 Jan 28.
Published in final edited form as: Cancer Lett. 2020 Jan 28; 469: 195–206. Published online 2019 Oct 28. doi: 10.1016/j.canlet.2019.10.034
PMCID:
PMC6905085
AbstractArticlePDF–2.4M
19.
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma
Nathan R. Fons, Ranjini K. Sundaram, Gregory A. Breuer, Sen Peng, Ryan L. McLean, Aravind N. Kalathil, Mark S. Schmidt, Diana M. Carvalho, Alan Mackay, Chris Jones, Ángel M. Carcaboso, Javad Nazarian, Michael E. Berens, Charles Brenner, Ranjit S. Bindra
Nat Commun. 2019; 10: 3790. Published online 2019 Aug 22. doi: 10.1038/s41467-019-11732-6
PMCID:
PMC6706443
AbstractArticlePDF–1.3M
20.
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas
Anika Bongaarts, Jackelien van Scheppingen, Anatoly Korotkov, Caroline Mijnsbergen, Jasper J Anink, Floor E Jansen, Wim G M Spliet, Wilfred F A den Dunnen, Victoria E Gruber, Theresa Scholl, Sharon Samueli, Johannes A Hainfellner, Martha Feucht, Katarzyna Kotulska, Sergiusz Jozwiak, Wieslawa Grajkowska, Anna Maria Buccoliero, Chiara Caporalini, Flavio Giordano, Lorenzo Genitori, Roland Coras, Ingmar Blümcke, Pavel Krsek, Josef Zamecnik, Lisethe Meijer, Brendon P Scicluna, Antoinette Y N Schouten-van Meeteren, Angelika Mühlebner, James D Mills, Eleonora Aronica
Brain. 2020 Jan; 143(1): 131–149. Published online 2019 Dec 13. doi: 10.1093/brain/awz370
Correction in:
Brain. 2020 Mar; 143(3): e24.
PMCID:
PMC6935755
AbstractArticlePDF–2.4M

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