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Select item 47912051.

YAP Induces High-Grade Serous Carcinoma in Fallopian Tube Secretory Epithelial Cells

Guohua Hua, Xiangmin Lv, Chunbo He, Steven W. Remmenga, Kerry J. Rodabough, Jixin Dong, Liguo Yang, Subodh M. Lele, Peixin Yang, Jin Zhou, Alison Karst, Ronny I. Drapkin, John S. Davis, Cheng Wang

Oncogene. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Oncogene. 2016 Apr 28; 35(17): 2247–2265. Published online 2015 Sep 14. doi: 10.1038/onc.2015.288

PMCID:: PMC4791205

Abstract Article PDF–2.4M

Select item 50780512.

Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium

Laura H. Rodgers, Eoghainín Ó hAinmhire, Alexandria N. Young, Joanna E. Burdette

Oncotarget. 2016 May 31; 7(22): 32785–32795. Published online 2016 Apr 27. doi: 10.18632/oncotarget.9051

PMCID:: PMC5078051

Abstract Article PDF–5.7M

Select item 50074613.

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

F. Coscia, K. M. Watters, M. Curtis, M. A. Eckert, C. Y. Chiang, S. Tyanova, A. Montag, R. R. Lastra, E. Lengyel, M. Mann

Nat Commun. 2016; 7: 12645. Published online 2016 Aug 26. doi: 10.1038/ncomms12645

PMCID:: PMC5007461

Abstract Article PDF–3.2M

Select item 50066414.

Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies

Karin Hellner, Fabrizio Miranda, Donatien Fotso Chedom, Sandra Herrero-Gonzalez, Daniel M. Hayden, Rick Tearle, Mara Artibani, Mohammad KaramiNejadRanjbar, Ruth Williams, Kezia Gaitskell, Samar Elorbany, Ruoyan Xu, Alex Laios, Petronela Buiga, Karim Ahmed, Sunanda Dhar, Rebecca Yu Zhang, Leticia Campo, Kevin A. Myers, María Lozano, María Ruiz-Miró, Sónia Gatius, Alba Mota, Gema Moreno-Bueno, Xavier Matias-Guiu, Javier Benítez, Lorna Witty, Gil McVean, Simon Leedham, Ian Tomlinson, Radoje Drmanac, Jean-Baptiste Cazier, Robert Klein, Kevin Dunne, Robert C. Bast, Jr, Stephen H. Kennedy, Bassim Hassan, Stefano Lise, María José Garcia, Brock A. Peters, Christopher Yau, Tatjana Sauka-Spengler, Ahmed Ashour Ahmed

EBioMedicine. 2016 Aug; 10: 137–149. Published online 2016 Jul 2. doi: 10.1016/j.ebiom.2016.06.048

PMCID:: PMC5006641

Abstract Article PDF–1.5M

Select item 50052615.

Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis

Stav Sapoznik, Keren Bahar-Shany, Hadar Brand, Yishay Pinto, Orshay Gabay, Efrat Glick-Saar, Chen Dor, Oranit Zadok, Iris Barshack, Adi Zundelevich, Einav Nili Gal-Yam, Yuval Yung, Ariel Hourvitz, Jacob Korach, Mario Beiner, Jasmine Jacob, Erez Y. Levanon, Michal Barak, Sarit Aviel-Ronen, Keren Levanon

Neoplasia. 2016 Feb; 18(2): 90–99. Published online 2016 Feb 29. doi: 10.1016/j.neo.2015.12.003

PMCID:: PMC5005261

Abstract Article PDF–1.2M

Select item 49774846.

Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression

C Duckworth, L Zhang, S L Carroll, S P Ethier, H W Cheung

Oncogene. 2016 Aug 4; 35(31): 4036–4047. Published online 2015 Dec 14. doi: 10.1038/onc.2015.472

PMCID:: PMC4977484

Abstract Article PDF–2.4M

Select item 49640887.

MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib

Margaret E. Whicker, Z. Ping Lin, Ruth Hanna, Alan C. Sartorelli, Elena S. Ratner

BMC Cancer. 2016; 16: 550. Published online 2016 Jul 27. doi: 10.1186/s12885-016-2598-1

PMCID:: PMC4964088

Abstract Article PDF–1.7M

Select item 49512088.

PAX8 Expression in Ovarian Surface Epithelial Cells

Emily Adler, Paulette Mhawech-Fauceglia, Simon A Gayther, Kate Lawrenson

Hum Pathol. Author manuscript; available in PMC 2016 Jul 19.

Published in final edited form as: Hum Pathol. 2015 Jul; 46(7): 948–956. Published online 2015 Apr 15. doi: 10.1016/j.humpath.2015.03.017

PMCID:: PMC4951208

Abstract Article PDF–653K

Select item 48901829.

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

Thomas E. Bartlett, Kantaraja Chindera, Jacqueline McDermott, Charles E. Breeze, William R. Cooke, Allison Jones, Daniel Reisel, Smita T. Karegodar, Rupali Arora, Stephan Beck, Usha Menon, Louis Dubeau, Martin Widschwendter

Nat Commun. 2016; 7: 11620. Published online 2016 May 24. doi: 10.1038/ncomms11620

PMCID:: PMC4890182

Abstract Article PDF–930K

Select item 487271910.

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

Juliet D. French, Sharon E. Johnatty, Yi Lu, Jonathan Beesley, Bo Gao, Murugan Kalimutho, Michelle J. Henderson, Amanda J. Russell, Siddhartha Kar, Xiaoqing Chen, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Martin O'Reilly, Chen Wang, Darren J. Korbie, Australian Ovarian Cancer Study Group, Australian Cancer Study, Diether Lambrechts, Evelyn Despierre, Els Van Nieuwenhuysen, Sandrina Lambrechts, Ignace Vergote, Beth Karlan, Jenny Lester, Sandra Orsulic, Christine Walsh, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Alexander Hein, Keitaro Matsuo, Satoyo Hosono, Jacobus Pisterer, Peter Hillemanns, Toru Nakanishi, Yasushi Yatabe, Marc T. Goodman, Galina Lurie, Rayna K. Matsuno, Pamela J. Thompson, Tanja Pejovic, Yukie Bean, Florian Heitz, Philipp Harter, Andreas du Bois, Ira Schwaab, Estrid Hogdall, Susanne K. Kjaer, Allan Jensen, Claus Hogdall, Lene Lundvall, Svend Aage Engelholm, Bob Brown, James M. Flanagan, Michelle D. Metcalf, Nadeem Siddiqui, Thomas Sellers, Brooke Fridley, Julie Cunningham, Joellen M. Schildkraut, Ed Iversen, Rachel Palmieri Weber, Donal Brennan, Andrew Berchuck, Paul Pharoah, Paul Harnett, Murray D. Norris, Michelle Haber, Ellen L. Goode, Jason S. Lee, Kum Kum Khanna, Kerstin B. Meyer, Georgia Chenevix-Trench, Anna deFazio, Stacey L. Edwards, Stuart MacGregor

Oncotarget. 2016 Feb 9; 7(6): 6353–6368. Published online 2016 Jan 31. doi: 10.18632/oncotarget.7047

PMCID:: PMC4872719

Abstract Article PDF–4.1M

Select item 516491511.

Genomics of ovarian cancer progression reveals diverse metastatic trajectories including intraepithelial metastasis to the fallopian tube

Mark A. Eckert, Shawn Pan, Kyle M. Hernandez, Rachel M. Loth, Jorge Andrade, Samuel L. Volchenboum, Pieter Faber, Anthony Montag, Ricardo Lastra, Marcus E. Peter, S. Diane Yamada, Ernst Lengyel

Cancer Discov. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Cancer Discov. 2016 Dec; 6(12): 1342–1351. Published online 2016 Oct 7. doi: 10.1158/2159-8290.CD-16-0607

PMCID:: PMC5164915

Abstract Article PDF–1.5M

Select item 477900712.

Prognostic Value of KIF2A and HER2-Neu Overexpression in Patients With Epithelial Ovarian Cancer

Di Wang, Huijun Zhu, Qing Ye, Chenyi Wang, Yunzhao Xu

Medicine (Baltimore) 2016 Feb; 95(8): e2803. Published online 2016 Mar 3. doi: 10.1097/MD.0000000000002803

PMCID:: PMC4779007

Abstract Article PDF–639K

Select item 477842013.

Shortened Telomeres in Serous Tubal Intraepithelial Carcinoma: An Early Event in Ovarian High-grade Serous Carcinogenesis

Elisabetta Kuhn, Alan Meeker, Tian-Li Wang, Ann Smith Sehdev, Robert J. Kurman, Ie-Ming Shih

Am J Surg Pathol. Author manuscript; available in PMC 2016 Mar 4.

Published in final edited form as: Am J Surg Pathol. 2010 Jun; 34(6): 829–836. doi: 10.1097/PAS.0b013e3181dcede7

PMCID:: PMC4778420

Abstract Article PDF–1.6M

Select item 477075114.

Role of miR-182 in response to oxidative stress in the cell fate of human fallopian tube epithelial cells

Yugang Liu, Wenan Qiang, Xiaofei Xu, Ruifen Dong, Alison M. Karst, Zhaojian Liu, Beihua Kong, Ronny I. Drapkin, Jian-Jun Wei

Oncotarget. 2015 Nov 17; 6(36): 38983–38998. Published online 2015 Oct 12. doi: 10.18632/oncotarget.5493

PMCID:: PMC4770751

Abstract Article PDF–1.9M

Select item 475484015.

Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators

Georgette Moyle-Heyrman, Matthew J. Schipma, Matthew Dean, David A. Davis, Joanna E. Burdette

J Ovarian Res. 2016; 9: 5. Published online 2016 Feb 15. doi: 10.1186/s13048-016-0213-3

PMCID:: PMC4754840

Abstract Article PDF–2.5M

Select item 465302116.

Tumorigenesis and peritoneal colonization from fallopian tube epithelium

Sharon L. Eddie, Suzanne M. Quartuccio, Eoghainin Ó hAinmhire, Georgette Moyle-Heyrman, Dan D. Lantvit, Jian-Jun Wei, Barbara C. Vanderhyden, Joanna E. Burdette

Oncotarget. 2015 Aug 21; 6(24): 20500–20512. Published online 2015 May 4. doi: 10.18632/oncotarget.3985

PMCID:: PMC4653021

Abstract Article PDF–6.2M

Select item 462257917.

DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer

Wa Zhang, Carter J Barger, Petra A Link, Paulette Mhawech-Fauceglia, Austin Miller, Stacey N Akers, Kunle Odunsi, Adam R Karpf

Epigenetics. 2015 Aug; 10(8): 736–748. Published online 2015 Jun 22. doi: 10.1080/15592294.2015.1062206

PMCID:: PMC4622579

Abstract Article PDF–1.5M

Select item 451794418.

Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube derived high-grade serous ovarian cancers

Alison M. Karst, Paul M. Jones, Natalie Vena, Azra H. Ligon, Joyce F. Liu, Michelle S. Hirsch, Dariush Etemadmoghadam, David D. L. Bowtell, Ronny Drapkin

Cancer Res. Author manuscript; available in PMC 2015 Jul 28.

Published in final edited form as: Cancer Res. 2014 Feb 15; 74(4): 1141–1152. Published online 2013 Dec 23. doi: 10.1158/0008-5472.CAN-13-2247

PMCID:: PMC4517944

Abstract Article PDF–2.0M

Select item 450349819.

Mutant p53 expression in fallopian tube epithelium drives cell migration

Suzanne M. Quartuccio, Subbulakshmi Karthikeyan, Sharon L. Eddie, Daniel D. Lantvit, Eoghainín Ó hAinmhire, Dimple A. Modi, Jian-Jun Wei, Joanna E. Burdette

Int J Cancer. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Int J Cancer. 2015 Oct 1; 137(7): 1528–1538. Published online 2015 Apr 11. doi: 10.1002/ijc.29528

PMCID:: PMC4503498

Abstract Article PDF–2.6M

Select item 549503620.

Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?

Nyamdelger Sukhbaatar, Anna Bachmayr-Heyda, Katharina Auer, Stefanie Aust, Simon Deycmar, Reinhard Horvat, Dietmar Pils

Cold Spring Harb Mol Case Stud. 2017 Jul; 3(4): a001461. doi: 10.1101/mcs.a001461

PMCID:: PMC5495036

Abstract Article PDF–1.7M

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