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Select item 79796221.

Controversies in the treatment of RAS wild-type metastatic colorectal cancer

R. Vera, M. Salgado, M. J. Safont, J. Gallego, E. González, E. Élez, E. Aranda

Clin Transl Oncol. 2021; 23(4): 827–839. Published online 2020 Aug 13. doi: 10.1007/s12094-020-02475-8

PMCID:: PMC7979622

Abstract Article PDF–596K

Select item 78783312.

AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review

Anne F. Peery, Aasma Shaukat, Lisa L. Strate

Gastroenterology. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Gastroenterology. 2021 Feb; 160(3): 906–911.e1. Published online 2020 Dec 3. doi: 10.1053/j.gastro.2020.09.059

PMCID:: PMC7878331

Abstract Article PDF–161K

Select item 111451593.

Clinical Challenges of Consensus Molecular Subtype CMS4 Colon Cancer in the Era of Precision Medicine

Sophie Mouillet-Richard, Antoine Cazelles, Marine Sroussi, Claire Gallois, Julien Taieb, Pierre Laurent-Puig

Clin Cancer Res. 2024 Jun 3; 30(11): 2351–2358. Published online 2024 Apr 2. doi: 10.1158/1078-0432.CCR-23-3964

PMCID:: PMC11145159

Abstract Article PDF–3.0M

Select item 111434674.

Budget Impact Analysis of Circulating Tumor DNA Testing for Colon Cancer in Commercial Health and Medicare Advantage Plans

Yonghong Li, Avneet K. Heer, Hillary S. Sloane, Daniel L. Edelstein, Jeanne Tie, Peter Gibbs, Afsaneh Barzi

JAMA Health Forum. 2024 May; 5(5): e241270. Published online 2024 May 31. doi: 10.1001/jamahealthforum.2024.1270

PMCID:: PMC11143467

Abstract Article

Select item 111426495.

Characterization of the Small Bowel Microbiome Reveals Different Profiles in Human Subjects Who Are Overweight or Have Obesity

Gabriela Leite, Gillian M. Barlow, Mohamad Rashid, Ava Hosseini, Daniel Cohrs, Gonzalo Parodi, Walter Morales, Stacy Weitsman, Ali Rezaie, Mark Pimentel, Ruchi Mathur

Am J Gastroenterol. 2024 Jun; 119(6): 1141–1153. Published online 2024 Apr 5. doi: 10.14309/ajg.0000000000002790

PMCID:: PMC11142649

Abstract Article PDF–845K

Select item 111415786.

Dual-mRNA Delivery Using Tumor Cell Lysate-Based Multifunctional Nanoparticles as an Efficient Colon Cancer Immunogene Therapy

Kaiyu Wang, Yan Gao, Shan Wu, Jin Zhang, Manfang Zhu, Xiayu Chen, Xizi Fu, Xingmei Duan, Ke Men

Int J Nanomedicine. 2024; 19: 4779–4801. Published online 2024 May 27. doi: 10.2147/IJN.S452548

PMCID:: PMC11141578

Abstract Article PDF–19M

Select item 111398877.

CILP2 is a potential biomarker for the prediction and therapeutic target of peritoneal metastases in colorectal cancer

Ye Jin Ha, Seong-Hwan Park, Ka Hee Tak, Jong Lyul Lee, Chan Wook Kim, Jeong-Hwan Kim, Seon-Young Kim, Seon-Kyu Kim, Yong Sik Yoon

Sci Rep. 2024; 14: 12487. Published online 2024 May 31. doi: 10.1038/s41598-024-63366-4

PMCID:: PMC11139887

Abstract Article PDF–2.8M

Select item 111398688.

TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression

Carli M. King, Wei Ding, Melanie A. Eshelman, Gregory S. Yochum

Sci Rep. 2024; 14: 12477. Published online 2024 May 30. doi: 10.1038/s41598-024-63346-8

PMCID:: PMC11139868

Abstract Article PDF–6.5M

Select item 111369969.

Combined inhibition of class 1-PI3K-alpha and delta isoforms causes senolysis by inducing p21^WAF1/CIP1 proteasomal degradation in senescent cells

Judith Neuwahl, Chantal A. Neumann, Annika C. Fitz, Anica D. Biermann, Maja Magel, Annabelle Friedrich, Lorenz Sellin, Björn Stork, Roland P. Piekorz, Peter Proksch, Wilfried Budach, Reiner U. Jänicke, Dennis Sohn

Cell Death Dis. 2024 May; 15(5): 373. Published online 2024 May 29. doi: 10.1038/s41419-024-06755-x

PMCID:: PMC11136996

Abstract Article PDF–4.7M

Select item 1113665310.

LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis

Nan Cao, Fangmei Zhang, Jiang Yin, Jianlei Zhang, Xiqing Bian, Guopei Zheng, Nan Li, Ying Lin, Liyun Luo

Oncogene. 2024; 43(22): 1714–1725. Published online 2024 Apr 11. doi: 10.1038/s41388-024-02996-4

PMCID:: PMC11136653

Abstract Article PDF–6.7M

Select item 1113570111.

A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system

Rodrigo Moreno-Campos, Eileen W. Singleton, Rosa A. Uribe

PLoS One. 2024; 19(5): e0303914. Published online 2024 May 29. doi: 10.1371/journal.pone.0303914

PMCID:: PMC11135701

Abstract Article PDF–3.4M

Select item 1113509512.

Identification of a 5-Gene Cuproptosis Signature Predicting the Prognosis for Colon Adenocarcinoma Based on WGCNA

Dongxue Wang, Funing Yang, Guiping Han, Jifeng Zhang, Hongjia Wang, Zunyu Xiao, Weiyu Chen, Ping Li

Technol Cancer Res Treat. 2024; 23: 15330338241250285. Published online 2024 May 27. doi: 10.1177/15330338241250285

PMCID:: PMC11135095

Abstract Article PDF–4.7M

Select item 1113490913.

SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells

Camilla Anastasio, Isabella Donisi, Vitale Del Vecchio, Antonino Colloca, Luigi Mele, Celestino Sardu, Raffaele Marfella, Maria Luisa Balestrieri, Nunzia D’Onofrio

Cell Mol Biol Lett. 2024; 29: 80. Published online 2024 May 29. doi: 10.1186/s11658-024-00599-1

PMCID:: PMC11134909

Abstract Article PDF–6.4M

Select item 1113430014.

The strength of gut microbiota transfer along social networks and genealogical lineages in the house mouse

Barbora Bendová, Barbora Vošlajerová Bímová, Dagmar Čížková, Kristina Daniszová, Ľudovít Ďureje, Zuzana Hiadlovská, Miloš Macholán, Jaroslav Piálek, Lucie Schmiedová, Jakub Kreisinger

FEMS Microbiol Ecol. 2024 Jun; 100(6): fiae075. Published online 2024 May 10. doi: 10.1093/femsec/fiae075

PMCID:: PMC11134300

Abstract Article PDF–1.5M

Select item 1113345915.

Memory CD8 T cells are vulnerable to chronic IFN-γ signals but not to CD4 T cell deficiency in MHCII-deficient mice

Ruka Setoguchi, Tomoya Sengiku, Hiroki Kono, Eiryo Kawakami, Masato Kubo, Tadashi Yamamoto, Shohei Hori

Nat Commun. 2024; 15: 4418. Published online 2024 May 28. doi: 10.1038/s41467-024-48704-4

PMCID:: PMC11133459

Abstract Article PDF–3.0M

Select item 1113199916.

Investigating gene signatures associated with immunity in colon adenocarcinoma to predict the immunotherapy effectiveness using NFM and WGCNA algorithms

Weizheng Liang, Xiangyu Yang, Xiushen Li, Peng Wang, Zhenpeng Zhu, Shan Liu, Dandan Xu, Xuejun Zhi, Jun Xue

Aging (Albany NY) 2024 May 15; 16(9): 7596–7621. Published online 2024 May 13. doi: 10.18632/aging.205763

PMCID:: PMC11131999

Abstract Article PDF–5.8M

Select item 1113197517.

Predictive value of FCGBP expression for treatment response and survival in rectal cancer patients undergoing chemoradiotherapy

Yu-Ting Su, Chung-Hsing Chen, Jui-Wen Kang, Hsin-Yu Kuo, Ching-Chieh Yang, Yu-Feng Tian, Cheng-Fa Yeh, Chia-Lin Chou, Shang-Hung Chen

Aging (Albany NY) 2024 May 15; 16(9): 7889–7901. Published online 2024 May 3. doi: 10.18632/aging.205791

PMCID:: PMC11131975

Abstract Article PDF–1.2M

Select item 1113030618.

Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance

Xiang-Ning Meng, Jin-Fa Ma, Yang-He Liu, Si-Qing Li, Xu Wang, Jing Zhu, Meng-Di Cai, Hui-Shu Zhang, Tiantian Song, Shukai Xing, Li-Qing Hou, Huan Guo, Xiao-Bo Cui, Jiang Han, Peng Liu, Guo-Hua Ji, Wen-Jing Sun, Jing-Cui Yu, Song-Bin Fu

Br J Cancer. 2024 May 27; 130(11): 1819–1827. Published online 2024 Apr 9. doi: 10.1038/s41416-024-02664-0

PMCID:: PMC11130306

Abstract Article PDF–2.6M

Select item 1113016819.

Identification of unique rectal cancer-specific subtypes

Batuhan Kisakol, Anna Matveeva, Manuela Salvucci, Alexander Kel, Elizabeth McDonough, Fiona Ginty, Daniel B. Longley, Jochen H. M. Prehn

Br J Cancer. 2024 May 27; 130(11): 1809–1818. Published online 2024 Mar 26. doi: 10.1038/s41416-024-02656-0

PMCID:: PMC11130168

Abstract Article PDF–2.2M

Select item 1112935720.

Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance

Hatim Boughanem, Jesús pilo, Libia Alejandra García-Flores, Isabel Arranz, María Ramos-Fernandez, María Ortega-Castan, Ana B. Crujeiras, Juan Sandoval, Manuel Macias-Gonzalez

J Transl Med. 2024; 22: 509. Published online 2024 May 27. doi: 10.1186/s12967-024-05329-x