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Select item 104006781.

Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage

Kana Sase, Chihiro Tsukahara, Naoki Fujita, Ibuki Arizono, Mizuki Otsubo, Yasushi Kitaoka

Int Ophthalmol. 2023; 43(9): 3067–3074. Published online 2023 Apr 16. doi: 10.1007/s10792-023-02706-1

PMCID:: PMC10400678

Article PDF–3.5M

Select item 100140052.

MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging

Keenan A. Walker, Michael R. Duggan, Zhaoyuan Gong, Heather E. Dark, John P. Laporte, Mary E. Faulkner, Yang An, Alexandria Lewis, Abhay R. Moghekar, Susan M. Resnick, Mustapha Bouhrara

Ann Clin Transl Neurol. 2023 Mar; 10(3): 397–407. Published online 2023 Feb 10. doi: 10.1002/acn3.51730

PMCID:: PMC10014005

Article PDF–1.3M

Select item 99090843.

Corneal axonal loss as an imaging biomarker of neurodegeneration in multiple sclerosis: a longitudinal study

Ioannis N. Petropoulos, Fatima Al-Shibani, Gulfidan Bitirgen, Georgios Ponirakis, Adnan Khan, Hoda Gad, Ziyad R. Mahfoud, Heba Altarawneh, Muhammad Hassan Rehman, Karen John, Dhabia Al-Merekhi, Pooja George, Ali Ulvi Uca, Ahmet Ozkagnici, Faiza Ibrahim, Reny Francis, Beatriz Canibano, Dirk Deleu, Ahmed El-Sotouhy, Surjith Vattoth, Ahmed Own, Ashfaq Shuaib, Naveed Akhtar, Saadat Kamran, Rayaz A. Malik

Ther Adv Neurol Disord. 2023; 16: 17562864221118731. Published online 2023 Feb 6. doi: 10.1177/17562864221118731

PMCID:: PMC9909084

Article PDF–958K

Select item 98280774.

Axonal loss at time of diagnosis as biomarker for long‐term disability in chronic inflammatory demyelinating polyneuropathy

Ali Al‐Zuhairy, Johannes Jakobsen, Mihai Moldovan, Christian Krarup

Muscle Nerve. 2022 Dec; 66(6): 715–722. Published online 2022 Oct 26. doi: 10.1002/mus.27722

PMCID:: PMC9828077

Article PDF–1.2M

Select item 95998765.

Modeling Reactive Oxygen Species-Induced Axonal Loss in Leber Hereditary Optic Neuropathy

Darius W. Lambiri, Leonard A. Levin

Biomolecules. 2022 Oct; 12(10): 1411. Published online 2022 Oct 2. doi: 10.3390/biom12101411

PMCID:: PMC9599876

Article PDF–5.4M

Select item 90060426.

Longitudinal tracking of axonal loss using diffusion magnetic resonance imaging in multiple sclerosis

Frederique M. Boonstra, Meaghan Clough, Myrte Strik, Anneke van der Walt, Helmut Butzkueven, Owen B. White, Meng Law, Joanne Fielding, Scott C. Kolbe

Brain Commun. 2022; 4(2): fcac065. Published online 2022 Mar 17. doi: 10.1093/braincomms/fcac065

PMCID:: PMC9006042

Article PDF–651K

Select item 88271017.

Clemastine Enhances Myelination, Delays Axonal Loss and Promotes Functional Recovery in Spinal Cord Injury

Weihong Du, Yongbing Deng, Rong Jiang, Luyao Tong, Ruixue Li, Xue Jiang

Neurochem Res. 2022; 47(2): 503–515. Published online 2021 Oct 18. doi: 10.1007/s11064-021-03465-0

PMCID:: PMC8827101

Article PDF–7.8M

Select item 87190148.

Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves

Hiromi Nakai-Shimoda, Tatsuhito Himeno, Tetsuji Okawa, Emiri Miura-Yura, Sachiko Sasajima, Makoto Kato, Yuichiro Yamada, Yoshiaki Morishita, Shin Tsunekawa, Yoshiro Kato, Yusuke Seino, Rieko Inoue, Masaki Kondo, Susumu Seino, Keiko Naruse, Koichi Kato, Hiroki Mizukami, Jiro Nakamura, Hideki Kamiya

iScience. 2022 Jan 21; 25(1): 103609. Published online 2021 Dec 11. doi: 10.1016/j.isci.2021.103609

PMCID:: PMC8719014

Article PDF–6.0M

Select item 85689439.

Corneal confocal microscopy demonstrates axonal loss in different courses of multiple sclerosis

Ioannis N. Petropoulos, Kathryn C. Fitzgerald, Jonathan Oakley, Georgios Ponirakis, Adnan Khan, Hoda Gad, Pooja George, Dirk Deleu, Beatriz G. Canibano, Naveed Akhtar, Ashfaq Shuaib, Ahmed Own, Taimur Malik, Daniel B. Russakoff, Joseph L. Mankowski, Stuti L. Misra, Charles N. J. McGhee, Peter Calabresi, Shiv Saidha, Saadat Kamran, Rayaz A. Malik

Sci Rep. 2021; 11: 21688. Published online 2021 Nov 4. doi: 10.1038/s41598-021-01226-1

PMCID:: PMC8568943

Article PDF–2.0M

Select item 856817410.

Myelination, axonal loss and Schwann cell characteristics in axonal polyneuropathy compared to controls

Eva Placheta-Györi, Lea Maria Brandstetter, Jakob Zemann-Schälss, Sonja Wolf, Christine Radtke

PLoS One. 2021; 16(11): e0259654. Published online 2021 Nov 4. doi: 10.1371/journal.pone.0259654

PMCID:: PMC8568174

Article PDF–1.9M

Select item 824464411.

Axonal loss in major sensorimotor tracts is associated with impaired motor performance in minimally disabled multiple sclerosis patients

Myrte Strik, L Eduardo Cofré Lizama, Camille J Shanahan, Anneke van der Walt, Frederique M C Boonstra, Rebecca Glarin, Trevor J Kilpatrick, Jeroen J G Geurts, Jon O Cleary, Menno M Schoonheim, Mary P Galea, Scott C Kolbe

Brain Commun. 2021; 3(2): fcab032. Published online 2021 Mar 16. doi: 10.1093/braincomms/fcab032

PMCID:: PMC8244644

Article PDF–2.7M

Select item 821063812.

Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease

Joana B Pereira, Shorena Janelidze, Rik Ossenkoppele, Hlin Kvartsberg, Ann Brinkmalm, Niklas Mattsson-Carlgren, Erik Stomrud, Ruben Smith, Henrik Zetterberg, Kaj Blennow, Oskar Hansson

Brain. 2021 Jan; 144(1): 310–324. Published online 2020 Dec 5. doi: 10.1093/brain/awaa395

PMCID:: PMC8210638

Article PDF–1022K

Select item 809431713.

Axonal Loss and Neurofilament Phosphorylation Changes Accompany Lesion Development and Clinical Progression in Multiple Sclerosis

Lucas Schirmer, Jack P. Antel, Wolfgang Brück, Christine Stadelmann

Brain Pathol. 2011 Jul; 21(4): 428–440. Published online 2011 Jan 10. doi: 10.1111/j.1750-3639.2010.00466.x

PMCID:: PMC8094317

Article PDF–1.6M

Select item 808311114.

Abnormal Dynamic Pupillometry Relates to Neurologic Disability and Retinal Axonal Loss in Patients With Multiple Sclerosis

Gulfidan Bitirgen, Zehra Akpinar, Huseyin B. Turk, Rayaz A. Malik

Transl Vis Sci Technol. 2021 Apr; 10(4): 30. Published online 2021 Apr 27. doi: 10.1167/tvst.10.4.30

PMCID:: PMC8083111

Article PDF–745K

Select item 802868215.

Axonal loss in the multiple sclerosis spinal cord revisited

Natalia Petrova, Daniele Carassiti, Daniel R. Altmann, David Baker, Klaus Schmierer

Brain Pathol. 2018 May; 28(3): 334–348. Published online 2017 May 7. doi: 10.1111/bpa.12516

PMCID:: PMC8028682

Article PDF–1.2M

Select item 796493516.

Measuring Myelin Repair and Axonal Loss with Diffusion Tensor Imaging

R.J. Fox, T. Cronin, J. Lin, X. Wang, K. Sakaie, D. Ontaneda, S.Y. Mahmoud, M.J. Lowe, M.D. Phillips

AJNR Am J Neuroradiol. 2011 Jan; 32(1): 85–91. doi: 10.3174/ajnr.A2238

PMCID:: PMC7964935

Article PDF–1.4M

Select item 792257817.

Dimethyl Fumarate Suppresses Demyelination and Axonal Loss through Reduction in Pro-Inflammatory Macrophage-Induced Reactive Astrocytes and Complement C3 Deposition

Sudhir K. Yadav, Naoko Ito, Devika Soin, Kouichi Ito, Suhayl Dhib-Jalbut

J Clin Med. 2021 Feb; 10(4): 857. Published online 2021 Feb 19. doi: 10.3390/jcm10040857

PMCID:: PMC7922578

Article PDF–3.6M

Select item 789779618.

Cortical axonal loss is associated with both gray matter demyelination and white matter tract pathology in progressive multiple sclerosis: Evidence from a combined MRI-histopathology study

Svenja Kiljan, Paolo Preziosa, Laura E Jonkman, Wilma DJ van de Berg, Jos Twisk, Petra JW Pouwels, Geert J Schenk, Maria A Rocca, Massimo Filippi, Jeroen JG Geurts, Martijn D Steenwijk

Mult Scler. 2021 Mar; 27(3): 380–390. Published online 2020 May 11. doi: 10.1177/1352458520918978

PMCID:: PMC7897796

Article PDF–2.1M

Select item 786258219.

Diffusion Basis Spectrum Imaging Detects Axonal Loss After Transient Dexamethasone Treatment in Optic Neuritis Mice

Tsen-Hsuan Lin, Jie Zhan, Chunyu Song, Michael Wallendorf, Peng Sun, Xuan Niu, Ruimeng Yang, Anne H. Cross, Sheng-Kwei Song

Front Neurosci. 2020; 14: 592063. Published online 2021 Jan 22. doi: 10.3389/fnins.2020.592063

PMCID:: PMC7862582

Article PDF–3.6M

Select item 778747220.

Differentiating axonal loss and demyelination in chronic MS lesions: A novel approach using single streamline diffusivity analysis

Samuel Klistorner, Michael H. Barnett, Jakob Wasserthal, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, Stuart L. Graham, Alexander Klistorner

PLoS One. 2021; 16(1): e0244766. Published online 2021 Jan 6. doi: 10.1371/journal.pone.0244766

PMCID:: PMC7787472

Article PDF–1.5M

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