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Select item 106631951.

The role of LOXL2 induced by glucose metabolism-activated NF-κB in maintaining drug resistance through EMT and cancer stemness in gemcitabine-resistant PDAC

Yun Sun Lee, Hyung Sun Kim, Hyo Jung Kim, Hyeon Woong Kang, Da Eun Lee, Myeong Jin Kim, Woosol Chris Hong, Ju Hyun Kim, Minsoo Kim, Jae-Ho Cheong, Joon Seong Park

J Mol Med (Berl) 2023; 101(11): 1449–1464. Published online 2023 Sep 22. doi: 10.1007/s00109-023-02369-6

PMCID:: PMC10663195

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Select item 106500032.

Correction: Felsenstein M. et al. Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies? J. Clin. Med. 2022, 11, 2367

Matthäus Felsenstein, Flora Lindhammer, Mathilde Feist, Karl Herbert Hillebrandt, Lea Timmermann, Christian Benzing, Brigitta Globke, Dario Zocholl, Mengwen Hu, Uli Fehrenbach, Bruno Valentin Sinn, Uwe Pelzer, Igor Maximillian Sauer, Johann Pratschke, Thomas Malinka

J Clin Med. 2023 Nov; 12(21): 6947. Published online 2023 Nov 6. doi: 10.3390/jcm12216947

Corrects:: J Clin Med. 2022 May; 11(9): 2367.

PMCID:: PMC10650003

Correction PDF–202K Cite

Select item 106361933.

An integrated study to decipher immunosuppressive cellular communication in the PDAC environment

Gülben AVŞAR, Pınar PİR

NPJ Syst Biol Appl. 2023; 9: 56. Published online 2023 Nov 10. doi: 10.1038/s41540-023-00320-6

PMCID:: PMC10636193

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Select item 106298224.

Mutant SF3B1 promotes malignancy in PDAC

Patrik Simmler, Eleonora I Ioannidi, Tamara Mengis, Kim Fabiano Marquart, Simran Asawa, Kjong Van-Lehmann, Andre Kahles, Tinu Thomas, Cornelia Schwerdel, Nicola Aceto, Gunnar Rätsch, Markus Stoffel, Gerald Schwank

eLife. 2023; 12: e80683. Published online 2023 Oct 12. doi: 10.7554/eLife.80683

PMCID:: PMC10629822

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Select item 106231795.

Regulatory role of RNA modifications in the treatment of pancreatic ductal adenocarcinoma (PDAC)

Hao Chen, Wenhao Luo, Xiaoyue Lu, Taiping Zhang

Heliyon. 2023 Nov; 9(11): e20969. Published online 2023 Oct 17. doi: 10.1016/j.heliyon.2023.e20969

PMCID:: PMC10623179

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Select item 106202396.

FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC

Jin Lu, Yongsheng Yang, Xiangliang Liu, Xiao Chen, Wei Song, Zefeng Liu

Cell Death Dis. 2023 Nov; 14(11): 713. Published online 2023 Nov 1. doi: 10.1038/s41419-023-06244-7

PMCID:: PMC10620239

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Select item 106184777.

SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN

Chuan-long Zhang, Qian Shen, Fu-dong Liu, Fan Yang, Meng-qi Gao, Xiao-chen Jiang, Yi Li, Xi-yuan Zhang, Ge-er En, Xue Pan, Bo Pang

Sci Rep. 2023; 13: 18727. Published online 2023 Oct 31. doi: 10.1038/s41598-023-44646-x

PMCID:: PMC10618477

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Select item 106076528.

Circulating miRNAs as Noninvasive Biomarkers for PDAC Diagnosis and Prognosis in Mexico

Lissuly Guadalupe Álvarez-Hilario, Eric Genaro Salmerón-Bárcenas, Pedro Antonio Ávila-López, Georgina Hernández-Montes, Elena Aréchaga-Ocampo, Roberto Herrera-Goepfert, Jorge Albores-Saavedra, María del Carmen Manzano-Robleda, Héctor Iván Saldívar-Cerón, Sandra Paola Martínez-Frías, María Del Rocío Thompson-Bonilla, Miguel Vargas, Rosaura Hernández-Rivas

Int J Mol Sci. 2023 Oct; 24(20): 15193. Published online 2023 Oct 14. doi: 10.3390/ijms242015193

PMCID:: PMC10607652

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Select item 105872489.

In-vitro model to mimic T cell subset change in human PDAC organoid co-culture

M. Knoblauch, T. Ma, I. Beirith, D. Koch, F. Hofmann, K. Heinrich, U. Aghamaliev, S. Sirtl, C. B. Westphalen, H. Nieß, M. Reichert, M. K. Angele, I. Regel, A. V. Bazhin, J. Werner, M. Ilmer, Bernhard W. Renz

J Cancer Res Clin Oncol. 2023; 149(14): 13051–13064. Published online 2023 Jul 20. doi: 10.1007/s00432-023-05100-7

PMCID:: PMC10587248

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Select item 1058358810.

Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2

Lanting Yu, Jiawei Lu, Ni Xie, Lutong Fang, Sumin Chen, Ying Wu, Xingpeng Wang, Baiwen Li

J Cancer. 2023; 14(16): 2964–2977. Published online 2023 Sep 11. doi: 10.7150/jca.85860

PMCID:: PMC10583588

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Select item 1052680211.

Circulating Tumor Cell Subpopulations Predict Treatment Outcome in Pancreatic Ductal Adenocarcinoma (PDAC) Patients

Ian M. Freed, Anup Kasi, Oluwadamilola Fateru, Mengjia Hu, Phasin Gonzalez, Nyla Weatherington, Harsh Pathak, Stephen Hyter, Weijing Sun, Raed Al-Rajabi, Joaquina Baranda, Mateusz L. Hupert, Prabhakar Chalise, Andrew K. Godwin, Malgorzata A. Witek, Steven A. Soper

Cells. 2023 Sep; 12(18): 2266. Published online 2023 Sep 13. doi: 10.3390/cells12182266

PMCID:: PMC10526802

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Select item 1051825612.

Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC

Xu Zhou, Jingyu An, Roma Kurilov, Benedikt Brors, Kai Hu, Teresa Peccerella, Stephanie Roessler, Katrin Pfütze, Angela Schulz, Stephan Wolf, Nicolas Hohmann, Dirk Theile, Max Sauter, Jürgen Burhenne, Shigenori Ei, Ulrike Heger, Oliver Strobel, Simon T. Barry, Christoph Springfeld, Christine Tjaden, Frank Bergmann, Markus Büchler, Thilo Hackert, Franco Fortunato, John P. Neoptolemos, Peter Bailey

Nat Cancer. 2023; 4(9): 1362–1381. Published online 2023 Sep 7. doi: 10.1038/s43018-023-00628-6

PMCID:: PMC10518256

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Select item 1050044913.

PAK4 inhibition significantly potentiates Gemcitabine activity in PDAC cells via inhibition of Wnt/β-catenin, p-ERK/MAPK and p-AKT/PI3K pathways

Charudatt Samant, Ramesh Kale, Anand Bokare, Mahip Verma, K. Sreedhara Ranganath Pai, Mandar Bhonde

Biochem Biophys Rep. 2023 Sep; 35: 101544. Published online 2023 Sep 9. doi: 10.1016/j.bbrep.2023.101544

PMCID:: PMC10500449

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Select item 1046203114.

Combined PI3K and MAPK inhibition synergizes to suppress PDAC

Bailey A. Bye, Jarrid Jack, Alexandra Pierce, R. McKinnon Walsh, Austin Eades, Prabhakar Chalise, Appolinaire Olou, Michael N. VanSaun

Version 1. bioRxiv. Preprint. 2023 Aug 17. doi: 10.1101/2023.08.15.553438

PMCID:: PMC10462031

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Select item 1046199915.

Adipose-Tumor Crosstalk contributes to CXCL5 Mediated Immune Evasion in PDAC

R. McKinnon Walsh, Joseph Ambrose, Jarrid L. Jack, Austin E. Eades, Bailey Bye, Mariana T. Ruckert, Appolinaire A. Olou, Fanuel Messaggio, Prabhakar Chalise, Dong Pei, Michael N. VanSaun

Version 1. bioRxiv. Preprint. 2023 Aug 16. doi: 10.1101/2023.08.15.553432

PMCID:: PMC10461999

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Select item 1036700316.

Whole-body bioluminescence imaging of T-cell response in PDAC models

Roisin McMorrow, Giorgia Zambito, Alex Nigg, Karishma Lila, Thierry P. P. van den Bosch, Clemens W. G. M. Lowik, Laura Mezzanotte

Front Immunol. 2023; 14: 1207533. Published online 2023 Jul 11. doi: 10.3389/fimmu.2023.1207533

PMCID:: PMC10367003

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Select item 1035954517.

IL-17A-producing CD8⁺ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

Felix Simon Ruben Picard, Veronika Lutz, Anna Brichkina, Felix Neuhaus, Teresa Ruckenbrod, Anna Hupfer, Hartmann Raifer, Matthias Klein, Tobias Bopp, Petra Ina Pfefferle, Rajkumar Savai, Immo Prinz, Ari Waisman, Sonja Moos, Hyun-Dong Chang, Stefan Heinrich, Detlef K Bartsch, Malte Buchholz, Shiv Singh, Mengyu Tu, Lukas Klein, Christian Bauer, Robert Liefke, Andreas Burchert, Ho-Ryun Chung, Philipp Mayer, Thomas M Gress, Matthias Lauth, Matthias Gaida, Magdalena Huber

Gut. 2023 Aug; 72(8): 1510–1522. Published online 2023 Feb 9. doi: 10.1136/gutjnl-2022-327855

PMCID:: PMC10359545

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Select item 1034841918.

The immunomodulatory role of IDO1-Kynurenine-NAD⁺ pathway in switching cold tumor microenvironment in PDAC

R. I. Anu, Kai-Keen Shiu, Khurum Hayat Khan

Front Oncol. 2023; 13: 1142838. Published online 2023 Jun 30. doi: 10.3389/fonc.2023.1142838

PMCID:: PMC10348419

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Select item 1034281519.

Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors

Natalia Michalak, Ewa Małecka-Wojciesko

J Clin Med. 2023 Jul; 12(13): 4318. Published online 2023 Jun 27. doi: 10.3390/jcm12134318

PMCID:: PMC10342815

Article PubReader PDF–657K Cite

Select item 1029921720.

CA 19-9 but Not IGF-1/IGFBP-2 Is a Useful Biomarker for Pancreatic Ductal Adenocarcinoma (PDAC) and Chronic Pancreatitis (CP) Differentiation

Barbara Wlodarczyk, Lukasz Durko, Przemyslaw Wlodarczyk, Renata Talar-Wojnarowska, Ewa Malecka-Wojciesko

J Clin Med. 2023 Jun; 12(12): 4050. Published online 2023 Jun 14. doi: 10.3390/jcm12124050

PMCID:: PMC10299217

Article PubReader PDF–996K Cite

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