PMC Articles for MedGen (Select 322023) - PMC

Select item 93877171.

Association of GLP1R Polymorphisms With the Incretin Response

Edgar G Dorsey-Trevino, Varinderpal Kaur, Josep M Mercader, Jose C Florez, Aaron Leong

J Clin Endocrinol Metab. 2022 Sep; 107(9): 2580–2588. Published online 2022 Jun 20. doi: 10.1210/clinem/dgac374

PMCID:: PMC9387717

Select item 86695352.

Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas

Adem Y. Dawed, Sook Wah Yee, Kaixin Zhou, Nienke van Leeuwen, Yanfei Zhang, Moneeza K. Siddiqui, Amy Etheridge, Federico Innocenti, Fei Xu, Josephine H. Li, Joline W. Beulens, Amber A. van der Heijden, Roderick C. Slieker, Yu-Chuan Chang, Josep M. Mercader, Varinderpal Kaur, John S. Witte, Ming Ta Michael Lee, Yoichiro Kamatani, Yukihide Momozawa, Michiaki Kubo, Colin N.A. Palmer, Jose C. Florez, Monique M. Hedderson, Leen M. ‘t Hart, Kathleen M. Giacomini, Ewan R. Pearson

Diabetes Care. 2021 Dec; 44(12): 2673–2682. Published online 2021 Oct 4. doi: 10.2337/dc21-1152

PMCID:: PMC8669535

Abstract Article PDF–1.4M

Select item 78818533.

A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas

Josephine H. Li, Lukasz Szczerbinski, Adem Y. Dawed, Varinderpal Kaur, Jennifer N. Todd, Ewan R. Pearson, Jose C. Florez

Diabetes. 2021 Jan; 70(1): 293–300. Published online 2020 Oct 26. doi: 10.2337/db20-0530

PMCID:: PMC7881853

Abstract Article PDF–628K

Select item 72111204.

The presence of two reduced function variants in CYP2C9 influences the acute response to glipizide

L. Chen, J. H. Li, V. Kaur, A. Muhammad, M. Fernandez, M. S. Hudson, A. B. Goldfine, J. C. Florez

Diabet Med. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Diabet Med. 2020 Dec; 37(12): 2124–2130. Published online 2019 Nov 25. doi: 10.1111/dme.14176

PMCID:: PMC7211120

Abstract Article PDF–666K

Select item 58299635.

TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

Shylaja Srinivasan, Varinderpal Kaur, Bindu Chamarthi, Katherine R. Littleton, Ling Chen, Alisa K. Manning, Jordi Merino, Melissa K. Thomas, Margo Hudson, Allison Goldfine, Jose C. Florez

Diabetes Care. 2018 Mar; 41(3): 554–561. Published online 2018 Jan 11. doi: 10.2337/dc17-1386

PMCID:: PMC5829963

Abstract Article PDF–908K

Select item 43748726.

The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH): Design of a pharmacogenetic Resource for Type 2 Diabetes

Geoffrey A. Walford, Natalia Colomo, Jennifer N. Todd, Liana K. Billings, Marlene Fernandez, Bindu Chamarthi, A. Sofia Warner, Jaclyn Davis, Katherine R. Littleton, Alicia M. Hernandez, Rebecca R. Fanelli, Amelia Lanier, Corinne Barbato, Rachel J. Ackerman, Sabina Q. Khan, Rosa Bui, Laurel Garber, Elliot S. Stolerman, Allan F. Moore, Chunmei Huang, Varinderpal Kaur, Maegan Harden, Andrew Taylor, Ling Chen, Alisa K. Manning, Paul Huang, Deborah Wexler, Rita M. McCarthy, Janet Lo, Melissa K. Thomas, Richard W. Grant, Allison Goldfine, Margo S. Hudson, Jose C. Florez

PLoS One. 2015; 10(3): e0121553. Published online 2015 Mar 26. doi: 10.1371/journal.pone.0121553

PMCID:: PMC4374872

Abstract Article PDF–717K

Select item 40806997.

Glimepiride reduces CD14 expression and cytokine secretion from macrophages

Victoria Ingham, Alun Williams, Clive Bate

J Neuroinflammation. 2014; 11: 115. Published online 2014 Jun 21. doi: 10.1186/1742-2094-11-115

PMCID:: PMC4080699

Abstract Article PDF–1.2M

Select item 15719658.

Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K⁺ channel Kir6.2 combination expressed in HEK-293 cells

Murali Gopalakrishnan, Eduardo J Molinari, Char-Chang Shieh, Lisa M Monteggia, Jean-Marc Roch, Kristi L Whiteaker, Victoria E S Scott, James P Sullivan, Jorge D Brioni

Br J Pharmacol. 2000 Apr; 129(7): 1323–1332. doi: 10.1038/sj.bjp.0703181

PMCID:: PMC1571965

Abstract Article PDF–304K

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