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Select item 97312081.

Case report: Optimized ruxolitinib-based therapy in an infant with familial hemophagocytic lymphohistiocytosis type 3

Daiki Niizato, Takeshi Isoda, Noriko Mitsuiki, Shuya Kaneko, Dan Tomomasa, Takahiro Kamiya, Masatoshi Takagi, Kohsuke Imai, Michiko Kajiwara, Masaki Shimizu, Tomohiro Morio, Hirokazu Kanegane

Front Immunol. 2022; 13: 977463. Published online 2022 Nov 23. doi: 10.3389/fimmu.2022.977463

PMCID:: PMC9731208

Article PDF–3.2M

Select item 91712372.

The Roles of FHL3 in Cancer

Zhenjun Huang, Chengpeng Yu, Liqing Yu, Hongxin Shu, Xianhua Zhu

Front Oncol. 2022; 12: 887828. Published online 2022 May 24. doi: 10.3389/fonc.2022.887828

PMCID:: PMC9171237

Article PDF–1.1M

Select item 82130273.

FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGFβ/Smad-Independent Pathways in Gastric Cancer

Guodong Cao, Pengping Li, Xiaobo He, Mengyao Jin, Mengying Li, Sihan Chen, Xin Xu, Qiang Sun, Maoming Xiong, Bo Chen

Front Oncol. 2021; 11: 649029. Published online 2021 Jun 4. doi: 10.3389/fonc.2021.649029

PMCID:: PMC8213027

Article PDF–12M

Select item 76429484.

The Conserved ASCL1/MASH-1 Ortholog HLH-3 Specifies Sex-Specific Ventral Cord Motor Neuron Fate in Caenorhabditis elegans

Lillian M. Perez, Aixa Alfonso

G3 (Bethesda) 2020 Nov; 10(11): 4201–4213. Published online 2020 Sep 24. doi: 10.1534/g3.120.401458

PMCID:: PMC7642948

Article PDF–2.6M

Select item 75339225.

MicroRNA-663 Regulates Melanoma Progression by Inhibiting FHL3

Saijun Liu, Yunfeng Hu, Shi Wu, Yong He, Liehua Deng

Technol Cancer Res Treat. 2020; 19: 1533033820957000. Published online 2020 Oct 1. doi: 10.1177/1533033820957000

Retraction in:: Technol Cancer Res Treat. 2021; 20: 15330338211039620.

PMCID:: PMC7533922

Article

Select item 73102026.

Lentiviral Gene Therapy for Familial Hemophagocytic Lymphohistiocytosis Type 3, Caused by UNC13D Genetic Defects

Sarah E. Takushi, Na Yoon Paik, Andrew Fedanov, Chengyu Prince, Christopher B. Doering, H. Trent Spencer, Shanmuganathan Chandrakasan

Hum Gene Ther. June 2020; 31(11-12): 626–638. Published online 2020 Jun 12. doi: 10.1089/hum.2019.329

PMCID:: PMC7310202

Article PDF–920K

Select item 71665207.

PCBP2 promotes the development of glioma by regulating FHL3/TGF‐β/Smad signaling pathway

Jianhui Mao, Zhaosheng Sun, Yongjian Cui, Naiyi Du, Hong Guo, Jianhui Wei, Zhenmin Hao, Lei Zheng

J Cell Physiol. 2020 Apr; 235(4): 3280–3291. Published online 2019 Nov 6. doi: 10.1002/jcp.29104

PMCID:: PMC7166520

Article PDF–3.6M

Select item 69776538.

FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors

Pengping Li, Guodong Cao, Yuefeng Zhang, Jingbo Shi, Kailun Cai, Lei Zhen, Xiaobo He, Yizhao Zhou, Yongzhou Li, Yi Zhu, Maoming Xiong, Yulian Wu

Aging (Albany NY) 2020 Jan 15; 12(1): 53–69. Published online 2020 Jan 13. doi: 10.18632/aging.102564

PMCID:: PMC6977653

Article PDF–4.1M

Select item 67483629.

Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3

Masashi Nishikawa, Katsuya Sato, Shun Nakano, Hisashi Yamakawa, Takahiro Nagase, Hiroshi Ueda

Small GTPases. 2019 Sep; 10(5): 361–366. Published online 2017 Jun 19. doi: 10.1080/21541248.2017.1327838

PMCID:: PMC6748362

Article PDF–637K

Select item 650500610.

FHL3 negatively regulates the differentiation of skeletal muscle satellite cells in chicken

Shunshun Han, Can Cui, Yan Wang, Haorong He, Xiaoxu Shen, Yuqi Chen, Zihao Liu, Qing Zhu, Diyan Li, Huadong Yin

3 Biotech. 2019 Jun; 9(6): 206. Published online 2019 May 7. doi: 10.1007/s13205-019-1735-3

PMCID:: PMC6505006

Article PDF–1.1M

Select item 646200511.

FHL3 links cell growth and self-renewal by modulating SOX4 in glioma

Wei Han, Peishan Hu, Fan Wu, Shanshan Wang, Yan Hu, Shanshan Li, Tao Jiang, Boqin Qiang, Xiaozhong Peng

Cell Death Differ. 2019 May; 26(5): 796–811. Published online 2018 Jun 28. doi: 10.1038/s41418-018-0152-1

PMCID:: PMC6462005

Article PDF–4.3M

Select item 452017612.

Direct Reversible Kidney Injury in Familial Hemophagocytic Lymphohistiocytosis Type 3

Laura Malaga-Dieguez, Wu Ming, Howard Trachtman

J Am Soc Nephrol. 2015 Aug; 26(8): 1777–1780. Published online 2015 Apr 9. doi: 10.1681/ASN.2014111090

PMCID:: PMC4520176

Article

Select item 432011513.

Angiogenin Promotes U87MG Cell Proliferation by Activating NF-κB Signaling Pathway and Downregulating Its Binding Partner FHL3

Wenrong Xia, Wenliang Fu, Xin Cai, Min Wang, Huihua Chen, Weiwei Xing, Yuanyuan Wang, Minji Zou, Tao Xu, Donggang Xu

PLoS One. 2015; 10(2): e0116983. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0116983

PMCID:: PMC4320115

Article PDF–671K

Select item 397213514.

Identification and Characterization of MT-1X as a Novel FHL3-Binding Partner

Xin Cai, JinFeng Wang, Xin Huang, Wenliang Fu, Wenrong Xia, Minji Zou, YuanYuan Wang, Jiaxi Wang, Donggang Xu

PLoS One. 2014; 9(4): e93723. Published online 2014 Apr 1. doi: 10.1371/journal.pone.0093723

PMCID:: PMC3972135

Article PDF–682K

Select item 363571415.

RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3

Wei Han, Zhongshuai Xin, Zhiqiang Zhao, Wen Bao, Xihua Lin, Bin Yin, Jizong Zhao, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng

J Clin Invest. 2013 May 1; 123(5): 2103–2118. Published online 2013 Apr 15. doi: 10.1172/JCI61820

PMCID:: PMC3635714

Article PDF–4.9M

Select item 184766316.

Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells

Annette P Meeson, Xiaozhong Shi, Matthew S Alexander, R S Williams, Ronald E Allen, Nan Jiang, Ibrahim M Adham, Sean C Goetsch, Robert E Hammer, Daniel J Garry

EMBO J. 2007 Apr 4; 26(7): 1902–1912. Published online 2007 Mar 15. doi: 10.1038/sj.emboj.7601635