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Select item 117057321.

APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression

Nora Hase, Danny Misiak, Helge Taubert, Stefan Hüttelmaier, Michael Gekle, Marcel Köhn

Mol Oncol. 2025 Jan; 19(1): 114–132. Published online 2024 Aug 26. doi: 10.1002/1878-0261.13721

PMCID:: PMC11705732

Abstract Article PDF–2.8M

Select item 117029502.

Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1

Xiao-Rong Huang, Lin Ye, Ning An, Chun-Yu Wu, Hong-Luan Wu, Hui-Yuan Li, Yan-Heng Huang, Qiao-Ru Ye, Ming-Dong Liu, La-Wei Yang, Jian-Xing Liu, Ji-Xin Tang, Qing-Jun Pan, Peng Wang, Lin Sun, Yin Xia, Hui-Yao Lan, Chen Yang, Hua-Feng Liu

Autophagy. 2025; 21(1): 120–140. Published online 2024 Aug 28. doi: 10.1080/15548627.2024.2393926

PMCID:: PMC11702950

Abstract Article PDF–7.9M

Select item 117000593.

Molecular and computational analysis of a novel pathogenic variant in emopamil-binding protein (EBP) involved in cholesterol biosynthetic pathway causing a rare male EBP disorder with neurologic defects (MEND syndrome)

Hadiba Bibi, Riaz Ahmad, Fatima Rahman, Shazia Maqbool, Muhammad Naeem, Stephanie Efthymiou, Henry Houlden

Mol Biol Rep. 2025; 52(1): 101. Published online 2025 Jan 4. doi: 10.1007/s11033-024-10183-7

PMCID:: PMC11700059

Abstract Article PDF–1.7M

Select item 116997404.

Reduced S-nitrosylation of TGFβ1 elevates its binding affinity toward the receptor and promotes fibrogenic signaling in the breast

Joshua Letson, Gang Ren, Xunzhen Zheng, Osama Sweef, Yalitza Lopes Corcino, Saori Furuta

J Biol Chem. 2024 Dec; 300(12): 108011. Published online 2024 Nov 20. doi: 10.1016/j.jbc.2024.108011

PMCID:: PMC11699740

Abstract Article PDF–4.8M

Select item 116991675.

IDO1 inhibitor enhances the effectiveness of PD-1 blockade in microsatellite stable colorectal cancer by promoting macrophage pro-inflammatory phenotype polarization

Lv Guangzhao, Wang Xin, Wu Miaoqing, Ma Wenjuan, Liu Ranyi, Pan Zhizhong, Zhang Rongxin, Chen Gong

Cancer Immunol Immunother. 2025 Feb; 74(2): 71. Published online 2025 Jan 3. doi: 10.1007/s00262-024-03925-w

PMCID:: PMC11699167

Abstract Article PDF–14M

Select item 116979116.

Role of the Notch signaling pathway in porcine oocyte maturation

Pil-Soo Jeong, Hyo-Gu Kang, Dabin Cha, Se-Been Jeon, Min Ju Kim, Bong-Seok Song, Bo-Woong Sim, Sanghoon Lee

Cell Commun Signal. 2025; 23: 1. Published online 2025 Jan 2. doi: 10.1186/s12964-024-01996-x

PMCID:: PMC11697911

Abstract Article PDF–8.9M

Select item 116938627.

Structural basis for the inhibition of coronaviral main proteases by PF-00835231: Crystal structures of M ^pro and M ^pro mutants bound to PF-00835231

Xuelan Zhou, Xiaolu Lu, Cheng Lin, Xiaofang Zou, Wenwen Li, Xiangyi Zeng, Jie Wang, Pei Zeng, Weiwei Wang, Jin Zhang, Haihai Jiang, Jian Li

Acta Biochim Biophys Sin (Shanghai) 2024 Dec 25; 56(12): 1813–1822. Published online 2024 Jul 29. doi: 10.3724/abbs.2024122

PMCID:: PMC11693862

Abstract Article PDF–2.3M

Select item 116870208.

YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway

Tai Tian, Shiming He, Han Hao, Bao Guan, Yanqing Gong, Jian Fan, Zhenpeng Zhu, Wenzhi Gao, Yucai Wu, Ninghan Feng, Aixiang Wang, Yuexian Guo, Xuesong Li

J Transl Med. 2024; 22: 1159. Published online 2024 Dec 31. doi: 10.1186/s12967-024-06003-y

PMCID:: PMC11687020

Abstract Article PDF–5.3M

Select item 116857729.

HDAC3 inhibitors induce drug resistance by promoting IL-17 A production by T cells

Hao Chen, Anqi Qin, Fan Xu, Shuai Guo, Ge Zhang, Aihong Zhang, WenTing Li, Feng Tian, Quanhui Zheng

Sci Rep. 2024; 14: 31937. Published online 2024 Dec 30. doi: 10.1038/s41598-024-83447-8

PMCID:: PMC11685772

Abstract Article PDF–2.3M

Select item 1168545510.

Computational biology assisted exploration of phytochemicals derived natural inhibitors to block BZLF1 gene activation of Epstein–Bar virus in host

Muhammad Naveed, Muzamal Hussain, Tariq Aziz, Nimra Hanif, Nazia Kanwal, Arooj Arshad, Ayaz Ali Khan, Abdulrahman Alshammari, Metab Alharbi

Sci Rep. 2024; 14: 31664. Published online 2024 Dec 30. doi: 10.1038/s41598-024-81037-2

PMCID:: PMC11685455

Abstract Article PDF–2.3M

Select item 1168504111.

Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages

Wulin Aerbajinai, Jianqiong Zhu, Kyung Chin, Griffin P Rodgers

J Leukoc Biol. 2025 Jan; 117(1): qiae197. Published online 2024 Sep 7. doi: 10.1093/jleuko/qiae197

PMCID:: PMC11685041

Abstract Article PDF–1.3M

Select item 1168275312.

Clinical and molecular identification of Newcastle disease virus in naturally infected chicks in Thi-Qar province of Iraq

Hakeem Jawad Kadhim, Abbas Kamil Shlaga, Safaa Hussein Ali

Open Vet J. 2024 Nov; 14(11): 2817–2826. Published online 2024 Nov 30. doi: 10.5455/OVJ.2024.v14.i11.10

PMCID:: PMC11682753

Abstract Article PDF–1.0M

Select item 1167275213.

A gain‐of‐function mutation at the C‐terminus of FT‐D1 promotes heading by interacting with 14‐3‐3A and FDL6 in wheat

Yuting Li, Hongchun Xiong, Huijun Guo, Yongdun Xie, Linshu Zhao, Jiayu Gu, Huiyuan Li, Shirong Zhao, Yuping Ding, Chunyun Zhou, Zhengwu Fang, Luxiang Liu

Plant Biotechnol J. 2025 Jan; 23(1): 20–35. Published online 2024 Sep 14. doi: 10.1111/pbi.14474

PMCID:: PMC11672752

Abstract Article PDF–9.4M

Select item 1166882814.

Production of virus-like particles of FMDV by 3C protease cleaving precursor polyprotein P1 in vitro

Zhiyao Li, Yuqing Ma, Xu Nan, Hu Dong, Jianli Tang, Shuanghui Yin, Shiqi Sun, Endong Bao, Huichen Guo

Appl Microbiol Biotechnol. 2024; 108(1): 542. Published online 2024 Dec 24. doi: 10.1007/s00253-024-13376-z

PMCID:: PMC11668828

Abstract Article PDF–1.3M

Select item 1166802115.

TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway

Tong Sun, Zhiguang Yang

Biol Direct. 2024; 19: 135. Published online 2024 Dec 24. doi: 10.1186/s13062-024-00584-w

PMCID:: PMC11668021

Abstract Article PDF–17M

Select item 1166751316.

The pathogenicity of PSEN2 variants is tied to Aβ production and homology to PSEN1

Lei Liu, Stephanie A. Schultz, Adriana Saba, Hyun‐Sik Yang, Amy Li, Dennis J. Selkoe, Jasmeer P. Chhatwal

Alzheimers Dement. 2024 Dec; 20(12): 8867–8877. Published online 2024 Nov 19. doi: 10.1002/alz.14339

PMCID:: PMC11667513

Abstract Article PDF–1.5M

Select item 1166652617.

In silico neoantigen screening and HLA multimer-based validation identify immunogenic neopeptide in multifocal lung adenocarcinoma

Xin Wang, Lang Jiang, Juan Zhao, Mi Wu, Jin Xiong, Xiongwen Wu, Xiufang Weng

Front Immunol. 2024; 15: 1456209. Published online 2024 Dec 10. doi: 10.3389/fimmu.2024.1456209

PMCID:: PMC11666526

Abstract Article PDF–5.6M

Select item 1166646418.

Pharmacological restoration of GTP hydrolysis by mutant RAS

Antonio Cuevas-Navarro, Yasin Pourfarjam, Feng Hu, Diego J. Rodriguez, Alberto Vides, Ben Sang, Shijie Fan, Yehuda Goldgur, Elisa de Stanchina, Piro Lito

Nature. 2025; 637(8044): 224–229. Published online 2024 Oct 30. doi: 10.1038/s41586-024-08283-2

PMCID:: PMC11666464

Abstract Article PDF–7.5M

Select item 1165828219.

Candidate genes associated with fatty acid compositions in north American Atlantic salmon (Salmo salar)

Barbara L. Langille, Manuel Juárez, Nuria Prieto, Solomon Boison, Panya Sae Lim, Bruce D. Swift, Amber F. Garber

BMC Genomics. 2024; 25: 1208. Published online 2024 Dec 18. doi: 10.1186/s12864-024-11131-2

PMCID:: PMC11658282

Abstract Article PDF–2.4M

Select item 1165618820.

Tetracarpidium conophorum nuts (African walnuts) up‐regulated adiponectin and PPAR‐γ expressions with reciprocal suppression of TNF‐α gene in obesity

Grace Ufedo Umoru, Item Justin Atangwho, Esien David‐Oku, Daniel Ejim Uti, Eyuwa Ignatius Agwupuye, Uket Nta Obeten, Swastika Maitra, Vetriselvan Subramaniyan, Ling Shing Wong, Nada H. Aljarba, Vinoth Kumarasamy

J Cell Mol Med. 2024 Dec; 28(24): e70086. Published online 2024 Dec 19. doi: 10.1111/jcmm.70086