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Select item 111310441.

Comprehensive understanding of glioblastoma molecular phenotypes: classification, characteristics, and transition

Can Xu, Pengyu Hou, Xiang Li, Menglin Xiao, Ziqi Zhang, Ziru Li, Jianglong Xu, Guoming Liu, Yanli Tan, Chuan Fang

Cancer Biol Med. 2024 May 15; 21(5): 363–381. Published online 2024 May 6. doi: 10.20892/j.issn.2095-3941.2023.0510

PMCID:: PMC11131044

Abstract Article PDF–1007K

Select item 110936152.

STING activation reprograms the microenvironment to sensitize NF1-related malignant peripheral nerve sheath tumors for immunotherapy

Bandarigoda N. Somatilaka, Laasya Madana, Ali Sadek, Zhiguo Chen, Sanjay Chandrasekaran, Renee M. McKay, Lu Q. Le

J Clin Invest. 2024 May 15; 134(10): e176748. Published online 2024 Mar 19. doi: 10.1172/JCI176748

PMCID:: PMC11093615

Abstract Article PDF–17M

Select item 110678153.

Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol

Ilse A C Spiekman, Birgit S Geurts, Laurien J Zeverijn, Gijs F de Wit, Vincent van der Noort, Paul Roepman, Wendy W J de Leng, Anne M L Jansen, Benno Kusters, Laurens V Beerepoot, Filip Y F L de Vos, Derk-Jan A de Groot, Jan Willem B de Groot, Ann Hoeben, Jan Buter, Hans A J Gelderblom, Emile E Voest, Henk M W Verheul

Oncologist. 2024 May; 29(5): 431–440. Published online 2023 Dec 18. doi: 10.1093/oncolo/oyad320

PMCID:: PMC11067815

Abstract Article PDF–3.6M

Select item 110669214.

Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3 K27M-mutant glioma

Yazmin Odia, Carl Koschmann, Nicholas A Vitanza, Peter de Blank, Dolly Aguilera, Jeffrey Allen, Doured Daghistani, Matthew Hall, Ziad Khatib, Cassie Kline, Tobey MacDonald, Sabine Mueller, Shamia L Faison, Joshua E Allen, Odin J Naderer, Samuel C Ramage, Rohinton S Tarapore, Susan Lynne McGovern, Soumen Khatua, Wafik Zaky, Sharon L Gardner

Neuro Oncol. 2024 Apr; 26(Suppl 2): S155–S164. Published online 2024 May 3. doi: 10.1093/neuonc/noae001

PMCID:: PMC11066921

Abstract Article PDF–255K

Select item 110377685.

A case report: Immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy

K. A. O. Ellem, Michael G. E. O’Rourke, Gregory R. Johnson, Gordon Parry, Ihor S. Misko, Christopher W. Schmidt, Peter G. Parsons, Scott R. Burrows, Simone Cross, Andrew Fell, Chung-Leung Li, John R. Bell, Philip J. Dubois, Denis J. Moss, Michael F. Good, Anne Kelso, Lawrence K. Cohen, Glenn Dranoff, Richard C. Mulligan

Cancer Immunol Immunother. 1997 Mar; 44(1): 10–20. Published online 1997 Mar 1. doi: 10.1007/s002620050349

PMCID:: PMC11037768

Abstract Article PDF–1.1M

Select item 110070206.

Application of plasma circulating KRAS mutations as a predictive biomarker for targeted treatment of pancreatic cancer

Mi Rim Lee, Sang Myung Woo, Min Kyeong Kim, Sung‐Sik Han, Sang‐Jae Park, Woo Jin Lee, Dong‐eun Lee, Sun Il Choi, Wonyoung Choi, Kyong‐Ah Yoon, Jung Won Chun, Yun‐Hee Kim, Sun‐Young Kong

Cancer Sci. 2024 Apr; 115(4): 1283–1295. Published online 2024 Feb 13. doi: 10.1111/cas.16104

Correction in:: Cancer Sci. 2024 May 29

PMCID:: PMC11007020

Abstract Article PDF–6.8M

Select item 109130757.

Glioblastoma heterogeneity at single cell resolution

David Eisenbarth, Y. Alan Wang

Oncogene. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: Oncogene. 2023 Jun; 42(27): 2155–2165. Published online 2023 Jun 5. doi: 10.1038/s41388-023-02738-y

PMCID:: PMC10913075

Abstract Article PDF–990K

Select item 108094498.

mRNA-based precision targeting of neoantigens and tumor-associated antigens in malignant brain tumors

Vrunda Trivedi, Changlin Yang, Kelena Klippel, Oleg Yegorov, Christina von Roemeling, Lan Hoang-Minh, Graeme Fenton, Elizabeth Ogando-Rivas, Paul Castillo, Ginger Moore, Kaytora Long-James, Kyle Dyson, Bently Doonan, Catherine Flores, Duane A. Mitchell

Genome Med. 2024; 16: 17. Published online 2024 Jan 25. doi: 10.1186/s13073-024-01281-z

PMCID:: PMC10809449

Abstract Article PDF–5.9M

Select item 107212759.

The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling

Hye-Min Jeon, Yong Jae Shin, Jaehyun Lee, Nakho Chang, Dong-Hun Woo, Won Jun Lee, Dayna Nguyen, Wonyoung Kang, Hee Jin Cho, Heekyoung Yang, Jin-Ku Lee, Jason K. Sa, Yeri Lee, Dong Geon Kim, Benjamin W. Purow, Yeup Yoon, Do-Hyun Nam, Jeongwu Lee

JCI Insight. 2023 Nov 8; 8(21): e167049. Published online 2023 Nov 8. doi: 10.1172/jci.insight.167049

PMCID:: PMC10721275

Abstract Article PDF–14M

Select item 1069009710.

Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency

Anirban Das, Uri Tabori, Lauren C. Sambira Nahum, Natalie B. Collins, Rebecca Deyell, Rina Dvir, Cecile Faure-Conter, Timothy E. Hassall, Jane E. Minturn, Melissa Edwards, Elissa Brookes, Vanessa Bianchi, Adrian Levine, Simone C. Stone, Sumedha Sudhaman, Santiago Sanchez Ramirez, Ayse B. Ercan, Lucie Stengs, Jill Chung, Logine Negm, Gad Getz, Yosef E. Maruvka, Birgit Ertl-Wagner, Pamela S. Ohashi, Trevor Pugh, Cynthia Hawkins, Eric Bouffet, Daniel A. Morgenstern

Clin Cancer Res. 2023 Dec 1; 29(23): 4770–4783. Published online 2023 May 1. doi: 10.1158/1078-0432.CCR-23-0411

PMCID:: PMC10690097

Abstract Article PDF–8.3M

Select item 1068949711.

Caveolin-1 mediates the utilization of extracellular proteins for survival in refractory gastric cancer

Nahee Hwang, Bo Kyung Yoon, Kyu-Hye Chun, Hyeonhui Kim, Yoseob Lee, Jae-Won Kim, Hyeonuk Jeon, Tae-Hyun Kim, Mi-Young Kim, Sungsoon Fang, Jae-Ho Cheong, Jae-woo Kim

Exp Mol Med. 2023 Nov; 55(11): 2461–2472. Published online 2023 Nov 2. doi: 10.1038/s12276-023-01109-7

PMCID:: PMC10689497

Abstract Article PDF–7.0M

Select item 1065066512.

Aggressive PitNETs and Potential Target Therapies: A Systematic Review of Molecular and Genetic Pathways

Simona Serioli, Ludovico Agostini, Alberto Pietrantoni, Federico Valeri, Flavia Costanza, Sabrina Chiloiro, Barbara Buffoli, Amedeo Piazza, Pietro Luigi Poliani, Maria Peris-Celda, Federica Iavarone, Simona Gaudino, Marco Gessi, Giovanni Schinzari, Pier Paolo Mattogno, Antonella Giampietro, Laura De Marinis, Alfredo Pontecorvi, Marco Maria Fontanella, Liverana Lauretti, Guido Rindi, Alessandro Olivi, Antonio Bianchi, Francesco Doglietto

Int J Mol Sci. 2023 Nov; 24(21): 15719. Published online 2023 Oct 29. doi: 10.3390/ijms242115719

PMCID:: PMC10650665

Abstract Article PDF–3.2M

Select item 1063259813.

Advances in treatment of alveolar soft part sarcoma: an updated review

Tomohiro Fujiwara, Toshiyuki Kunisada, Eiji Nakata, Kenji Nishida, Hiroyuki Yanai, Tomoki Nakamura, Kazuhiro Tanaka, Toshifumi Ozaki

Jpn J Clin Oncol. 2023 Nov; 53(11): 1009–1018. Published online 2023 Aug 25. doi: 10.1093/jjco/hyad102

PMCID:: PMC10632598

Abstract Article PDF–967K

Select item 1054661814.

Intratumoral Injection of HSV1716, an Oncolytic Herpes Virus, is Safe and Shows Evidence of Immune Response and Viral Replication in Young Cancer Patients

Keri A. Streby, James I. Geller, Mark A. Currier, Patrick S. Warren, John M. Racadio, Alexander J. Towbin, Michele R. Vaughan, Melinda Triplet, Kristy Ott-Napier, Devon J. Dishman, Lori R. Backus, Beth Stockman, Marianne Brunner, Kathleen Simpson, Robert Spavin, Joe Conner, Timothy P. Cripe

Clin Cancer Res. Author manuscript; available in PMC 2023 Oct 3.

Published in final edited form as: Clin Cancer Res. 2017 Jul 15; 23(14): 3566–3574. Published online 2017 May 11. doi: 10.1158/1078-0432.CCR-16-2900

PMCID:: PMC10546618

Abstract Article PDF–705K

Select item 1048114215.

Refractory response to entrectinib for ROS‐1 rearranged NSCLC with concurrent de novo TP53 mutation showing good response to CNS lesion, but poor duration of response: A case report

Kentaro Ito, Miho Nishio, Kentaro Fujiwara, Yoichi Nishii, Kengo Ushiro, Hiroki Yasui, Osamu Hataji

Thorac Cancer. 2023 Sep; 14(25): 2622–2626. Published online 2023 Aug 6. doi: 10.1111/1759-7714.15044

PMCID:: PMC10481142

Abstract Article PDF–1.4M

Select item 1042322116.

Co-inhibition of glutaminolysis and one-carbon metabolism promotes ROS accumulation leading to enhancement of chemotherapeutic efficacy in anaplastic thyroid cancer

Yeseong Hwang, Hyeok Jun Yun, Jae Woong Jeong, Minki Kim, Seyeon Joo, Hae-Kyung Lee, Hang-Seok Chang, Seok-Mo Kim, Sungsoon Fang

Cell Death Dis. 2023 Aug; 14(8): 515. Published online 2023 Aug 12. doi: 10.1038/s41419-023-06041-2

PMCID:: PMC10423221

Abstract Article PDF–6.8M

Select item 1033341017.

Refractory corticotroph adenomas

Amit K. S. Sumal, Dongyun Zhang, Anthony P. Heaney

Pituitary. 2023; 26(3): 269–272. Published online 2023 Mar 14. doi: 10.1007/s11102-023-01308-5

PMCID:: PMC10333410

Abstract Article PDF–574K

Select item 1031483018.

Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors

Naoki Shinojima, Kazutaka Ozono, Haruaki Yamamoto, Sakiko Abe, Rumi Sasaki, Yusuke Tomita, Azusa Kai, Ryosuke Mori, Takahiro Yamamoto, Ken Uekawa, Hirotaka Matsui, Kisato Nosaka, Hiroaki Matsuzaki, Yoshihiro Komohara, Yoshiki Mikami, Akitake Mukasa

Brain Tumor Pathol. 2023; 40(3): 185–190. Published online 2023 Apr 22. doi: 10.1007/s10014-023-00461-w

PMCID:: PMC10314830

Abstract Article PDF–1.5M

Select item 1024883919.

Randomized Trial of First-Line Tyrosine Kinase Inhibitor With or Without Radiotherapy for Synchronous Oligometastatic EGFR-Mutated Non-Small Cell Lung Cancer

Xiao-Shan Wang, Yi-Feng Bai, Vivek Verma, Rui-Lian Yu, Wei Tian, Rui Ao, Ying Deng, Xue-Qiang Zhu, Hao Liu, Hai-Xia Pan, Lan Yang, Han-Song Bai, Xing Luo, Yan Guo, Ming-Xiu Zhou, Yue-Mei Sun, Zi-Can Zhang, Si-Min Li, Xue Cheng, Bang-Xian Tan, Liang-Fu Han, Ying-Yi Liu, Kai Zhang, Fan-Xin Zeng, Lin Jia, Xin-Bao Hao, You-Yu Wang, Gang Feng, Ke Xie, You Lu, Ming Zeng

J Natl Cancer Inst. 2023 Jun; 115(6): 742–748. Published online 2022 Jan 30. doi: 10.1093/jnci/djac015

Correction in:: J Natl Cancer Inst. 2023 Jun; 115(6): 773.

Expression of Concern in:: J Natl Cancer Inst. 2023 Jun; 115(6): 769.

PMCID:: PMC10248839

Abstract Article PDF–342K

Select item 1023663420.

Single‐cell RNA sequencing reveals tumor heterogeneity, microenvironment, and drug‐resistance mechanisms of recurrent glioblastoma

Haibin Wu, Chengcheng Guo, Chaoye Wang, Jiang Xu, Suyue Zheng, Jian Duan, Yiyun Li, Hongming Bai, Qiuyan Xu, Fangling Ning, Feng Wang, Qunying Yang

Cancer Sci. 2023 Jun; 114(6): 2609–2621. Published online 2023 Mar 10. doi: 10.1111/cas.15773

PMCID:: PMC10236634

Abstract Article PDF–13M

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