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Select item 117370911.

Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma

Liuyan Chen, Lvying Wu, Minying Tang, Yuanhang Cheng, Kuanyin Wang, Jianan Zhang, Wenyi Deng, Lingfeng Zhu, Jin Chen

BMC Urol. 2025; 25: 8. Published online 2025 Jan 16. doi: 10.1186/s12894-025-01694-x

PMCID:: PMC11737091

Article PDF–7.6M

Select item 117342252.

TFE3-rearranged perivascular epithelioid cell tumors of the head and neck with rare fusion partners: clues to the differential diagnosis between benign and malignant tumors

Yuka Takahashi, Akihiko Yoshida, Seiichi Yoshimoto, Shigenobu Suzuki, Satsuki Kishikawa, Ayaka Mitsui, Eijitsu Ryo, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Taisuke Mori

Diagn Pathol. 2025; 20: 7. Published online 2025 Jan 15. doi: 10.1186/s13000-025-01602-9

PMCID:: PMC11734225

Article PDF–2.4M

Select item 117306303.

RSK4 promotes the metastasis of clear cell renal cell carcinoma by activating RUNX1-mediated angiogenesis

Jing Ma, Yanru Yang, Kaijing Wang, Jin Liu, Junyi Feng, Gongcheng Wang, Shuangping Guo, Linni Fan

Cancer Biol Ther. 2025; 26(1): 2452025. Published online 2025 Jan 10. doi: 10.1080/15384047.2025.2452025

PMCID:: PMC11730630

Article PDF–3.5M

Select item 117296944.

Shiga Toxins Produced by Enterohaemorrhagic Escherichia coli Induce Inflammation in Toxin-Sensitive Cells through the p38 MAPK/MK2/Tristetraprolin Signaling Pathway

Seo Young Park, Yu-Jin Jeong, Kyung-Soo Lee, Jun-Young Park, Jongsun Park, Vernon L. Tesh, Moo-Seung Lee

J Microbiol Biotechnol. 2024 Dec 28; 34(12): 2439–2449. Published online 2024 Nov 22. doi: 10.4014/jmb.2410.10016

PMCID:: PMC11729694

Article PDF–2.4M

Select item 117292635.

HIF1α Plays a Crucial Role in the Development of TFE3–Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis

Hidekazu Nishizawa, Shintaro Funasaki, Wenjuan Ma, Yoshiaki Kubota, Kazuhide Watanabe, Yuichiro Arima, Shoichiro Kuroda, Takaaki Ito, Mitsuko Furuya, Takanobu Motoshima, Akira Nishiyama, Sally Mehanna, Yorifumi Satou, Hisashi Hasumi, Ryosuke Jikuya, Kazuhide Makiyama, Tomohiko Tamura, Yuichi Oike, Yasuhito Tanaka, Toshio Suda, Laura S. Schmidt, W. Marston Linehan, Masaya Baba, Tomomi Kamba

Genes Cells. 2025 Jan; 30(1): e13195. Published online 2025 Jan 14. doi: 10.1111/gtc.13195

PMCID:: PMC11729263

Article PDF–9.0M

Select item 117249836.

Integrated RNA sequencing analysis and machine learning identifies a metabolism-related prognostic signature in clear cell renal cell carcinoma

Yunxun Liu, Zhiwei Yan, Cheng Liu, Rui Yang, Qingyuan Zheng, Jun Jian, Minghui Wang, Lei Wang, Xiaodong Weng, Zhiyuan Chen, Xiuheng Liu

Sci Rep. 2025; 15: 1691. Published online 2025 Jan 11. doi: 10.1038/s41598-025-85618-7

PMCID:: PMC11724983

Article PDF–11M

Select item 117240437.

Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trial

Pavlos Msaouel, Kai Yu, Ying Yuan, Jianfeng Chen, Xinmiao Yan, Menuka Karki, Fei Duan, Rahul A. Sheth, Priya Rao, Kanishka Sircar, Amishi Y. Shah, Amado J. Zurita, Giannicola Genovese, Min Li, Chih-Chen Yeh, Minghao Dang, Guangchun Han, Yanshuo Chu, Max Hallin, Peter Olson, Rui Yang, Daniela Slavin, Hirak Der-Torossian, Curtis D. Chin, Nizar M. Tannir, Linghua Wang, Jianjun Gao

Nat Commun. 2025; 16: 578. Published online 2025 Jan 10. doi: 10.1038/s41467-024-55642-8

PMCID:: PMC11724043

Article PDF–5.4M

Select item 117213058.

Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti–CTLA-4 in renal cell carcinoma

David A. Schoenfeld, Dijana Djureinovic, David G. Su, Lin Zhang, Benjamin Y. Lu, Larisa Kamga, Jacqueline E. Mann, John D. Huck, Michael Hurwitz, David A. Braun, Lucia Jilaveanu, Aaron M. Ring, Harriet M. Kluger

JCI Insight. 2025 Jan 9; 10(1): e184545. Published online 2024 Nov 19. doi: 10.1172/jci.insight.184545

PMCID:: PMC11721305

Article PDF–8.9M

Select item 117174939.

Characterisation of GPR17‐expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses

Stefano Raffaele, Bettina Hjelm Clausen, Francesca Carolina Mannella, Martin Wirenfeldt, Davide Marangon, Sarah Boe Tidgen, Silvia Corradini, Kirsten Madsen, Davide Lecca, Maria Pia Abbracchio, Kate Lykke Lambertsen, Marta Fumagalli

J Pathol. 2025 Feb; 265(2): 226–243. Published online 2024 Dec 20. doi: 10.1002/path.6381

PMCID:: PMC11717493

Article PDF–31M

Select item 1171631810.

miR-9-5p/HMMR regulates the tumorigenesis and progression of clear cell renal cell carcinoma through EMT and JAK1/STAT1 signaling pathway

Xinyang Niu, Dingheng Lu, Weitao Zhan, Jiazhu Sun, Yuxiao Li, Yuchen Shi, Kai Yu, Suyuelin Huang, Xueyou Ma, Xiaoyan Liu, Ben Liu

J Transl Med. 2025; 23: 36. Published online 2025 Jan 9. doi: 10.1186/s12967-024-05988-w

PMCID:: PMC11716318

Article PDF–4.0M

Select item 1171416711.

STAMBPL1/TRIM21 Balances AXL Stability Impacting Mesenchymal Phenotype and Immune Response in KIRC

Shiyu Huang, Xuke Qin, Shujie Fu, Juncheng Hu, Zhengyu Jiang, Min Hu, Banghua Zhang, Jiachen Liu, Yujie Chen, Minghui Wang, Xiuheng Liu, Zhiyuan Chen, Lei Wang

Adv Sci (Weinh) 2025 Jan; 12(1): 2405083. Published online 2024 Nov 11. doi: 10.1002/advs.202405083

PMCID:: PMC11714167

Article PDF–19M

Select item 1171167212.

Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis

Hongyun Wang, Feizhou Li, Qiong Wang, Xinyuan Guo, Xinbing Chen, Xinrong Zou, Jun Yuan

Sci Rep. 2025; 15: 1294. Published online 2025 Jan 8. doi: 10.1038/s41598-024-84018-7

PMCID:: PMC11711672

Article PDF–13M

Select item 1170924013.

A retrospective single-center pilot study of the genetic background of the transplanted kidney

Anna Novotna, Klara Horackova, Jana Soukupova, Petra Zemankova, Petr Nehasil, Pavel Just, Ludek Voska, Petra Kleiblova, Silvie Rajnochova Bloudickova

PLoS One. 2025; 20(1): e0316192. Published online 2025 Jan 8. doi: 10.1371/journal.pone.0316192

PMCID:: PMC11709240

Article PDF–744K

Select item 1170573214.

APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression

Nora Hase, Danny Misiak, Helge Taubert, Stefan Hüttelmaier, Michael Gekle, Marcel Köhn

Mol Oncol. 2025 Jan; 19(1): 114–132. Published online 2024 Aug 26. doi: 10.1002/1878-0261.13721

PMCID:: PMC11705732

Article PDF–2.8M

Select item 1170563415.

HIF-2α/LPCAT1 orchestrates the reprogramming of lipid metabolism in ccRCC by modulating the FBXW7-mediated ubiquitination of ACLY

Mintian Fei, Yi Zhang, Haolin Li, Qili Xu, Yu Gao, Cheng Yang, Weiyi Li, Chaozhao Liang, Baojun Wang, Haibing Xiao

Int J Biol Sci. 2025; 21(2): 614–631. Published online 2025 Jan 1. doi: 10.7150/ijbs.103032

PMCID:: PMC11705634

Article PDF–11M

Select item 1170515616.

Up-regulation of Cuproptosis-related lncRNAS in Patients Receiving Immunotherapy for Metastatic Clear Cell Renal Cell Carcinoma Indicates Progressive Disease

HECTOR KATIFELIS, STAMATIKI GRAMMATIKAKI, ROUBINI ZAKOPOULOU, ARISTOTELIS BAMIAS, MICHALIS V. KARAMOUZIS, KONSTANTINOS STRAVODIMOS, MARIA GAZOULI

In Vivo. 2025 Jan-Feb; 39(1): 146–151. Published online 2025 Jan 3. doi: 10.21873/invivo.13812

PMCID:: PMC11705156

Article PDF–312K

Select item 1170478117.

Long-read structural and epigenetic profiling of a kidney tumor-matched sample with nanopore sequencing and optical genome mapping

Sapir Margalit, Zuzana Tulpová, Tahir Detinis Zur, Yael Michaeli, Jasline Deek, Gil Nifker, Rita Haldar, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Hagit Baris Feldman, Assaf Grunwald, Yuval Ebenstein

NAR Genom Bioinform. 2025 Mar; 7(1): lqae190. Published online 2025 Jan 7. doi: 10.1093/nargab/lqae190

PMCID:: PMC11704781

Article PDF–1.5M

Select item 1170083718.

Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication

Ran Yehuda, Ido Dromi, Yishai Levin, Thomas Carell, Nicholas Geacintov, Zvi Livneh

Oncogene. 2025; 44(1): 42–49. Published online 2024 Oct 28. doi: 10.1038/s41388-024-03192-0

PMCID:: PMC11700837

Article PDF–2.1M

Select item 1169763619.

Non-coding RNAs secreted by renal cancer include piR_004153 that promotes migration of mesenchymal stromal cells

Joanna Bogusławska, Małgorzata Grzanka, Piotr Popławski, Weronika Zarychta-Wiśniewska, Anna Burdzinska, Karolina Hanusek, Helena Kossowska, Roksana Iwanicka-Nowicka, Alex Białas, Beata Rybicka, Anna Adamiok-Ostrowska, Joanna Życka-Krzesińska, Marta Koblowska, Leszek Pączek, Agnieszka Piekiełko-Witkowska

Cell Commun Signal. 2025; 23: 3. Published online 2025 Jan 3. doi: 10.1186/s12964-024-02001-1

PMCID:: PMC11697636

Article PDF–2.0M

Select item 1169762520.

Discovering the interactome, functions, and clinical relevance of enhancer RNAs in kidney renal clear cell carcinoma

Zhaohui Sun, Haojie Du, Xudong Zheng, Hepeng Zhang, Huajie Hu

BMC Med Genomics. 2025; 18: 3. Published online 2025 Jan 3. doi: 10.1186/s12920-024-02081-5

PMCID:: PMC11697625

Article PDF–3.8M

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